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Extract from the Register of European Patents

EP About this file: EP1129717

EP1129717 - Use of homologues of staphylococcal enterotoxins for cancer treatment [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  01.02.2013
Database last updated on 17.12.2024
Most recent event   Tooltip28.06.2013Lapse of the patent in a contracting state
New state(s): DE		published on 31.07.2013  [2013/31]
Applicant(s)For all designated states
Terman, David S.
3183 Palmero Way
Pebble Beach, CA 93953 / US
For all designated states
STONE, Jay L.
2695 Estate Drive
Aptos, CA 95003 / US
[2013/10]
Former [2005/37]For all designated states
TERMAN, David S.
3183 Palmero Way
Pebble Beach, CA 93953 / US
For all designated states
STONE, Jay L.
2695 Estate Drive
Aptos, CA 95003 / US
Former [2001/36]For all designated states
TERMAN, David S.
3183 Palermo Way
Pebble Beach, CA 93953 / US
For all designated states
STONE, Jay L.
2695 Estate Drive
Aptos, CA 95003 / US
Inventor(s)01 / see applicant
...
 [2001/36]
Representative(s)Wichmann, Hendrik, et al
Wuesthoff & Wuesthoff
Patentanwälte und Rechtsanwalt PartG mbB
Schweigerstraße 2
81541 München / DE
[N/P]
Former [2013/10]Wichmann, Hendrik, et al
Wuesthoff & Wuesthoff Schweigerstrasse 2
81541 München / DE
Former [2010/42]Wichmann, Hendrik, et al
Wuesthoff & Wuesthoff Schweigstrasse 2
81541 München / DE
Former [2008/38]Wichmann, Hendrik, et al
Isenbruck Bösl Hörschler Wichmann Huhn Patentanwälte Prinzregentenstrasse 68
81675 München / DE
Former [2003/28]Wichmann, Hendrik, Dr., et al
Patentanwälte Isenbruck Bösl Hörschler Wichmann Huhn Postfach 86 08 80
81635 München / DE
Former [2001/36]Dost, Wolfgang, Dr. rer.nat., Dipl.-Chem., et al
Bardehle, Pagenberg & Partner, Galileiplatz 1
81679 München / DE
Application number, filing date01104586.117.01.1991
[2001/36]
Priority number, dateUS1990046657717.01.1990         Original published format: US 466577
[2001/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1129717
Date:05.09.2001
Language:EN
[2001/36]
Type: B1 Patent specification 
No.:EP1129717
Date:14.09.2005
Language:EN
[2005/37]
Type: B2 New European patent specification 
No.:EP1129717
Date:06.03.2013
Language:EN
[2013/10]
Search report(s)(Supplementary) European search report - dispatched on:EP24.07.2001
ClassificationIPC:A61K38/16, A61P35/00
[2001/36]
CPC:
C07K14/315 (EP); A61K31/192 (EP); A61K39/4611 (EP);
A61K39/4622 (EP); A61K39/4632 (EP); A61K39/464821 (EP);
A61K39/464822 (EP); A61K45/06 (EP); A61P35/00 (EP);
C07K14/31 (EP); A61K38/00 (EP); C12N2510/00 (EP) (-)
C-Set:
A61K31/192, A61K2300/00 (EP);
A61K39/464821, A61K2300/00 (EP);
A61K39/464822, A61K2300/00 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [2001/36]
TitleGerman:Verwendung von Staphylococcus Enterotoxin Homologe für Krebs-Therapie[2001/36]
English:Use of homologues of staphylococcal enterotoxins for cancer treatment[2001/36]
French:Utilisation des homologues des enterotoxines de Staphylococcus pour le traitement du cancer[2001/36]
Examination procedure06.03.2001Examination requested  [2001/36]
19.03.2002Despatch of a communication from the examining division (Time limit: M06)
17.09.2002Reply to a communication from the examining division
09.01.2003Despatch of a communication from the examining division (Time limit: M06)
25.08.2003Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
04.11.2003Reply to a communication from the examining division
17.05.2004Despatch of a communication from the examining division (Time limit: M04)
03.06.2004Reply to a communication from the examining division
03.12.2004Despatch of a communication from the examining division (Time limit: M04)
24.03.2005Reply to a communication from the examining division
06.05.2005Despatch of a communication from the examining division (Time limit: M04)
13.05.2005Reply to a communication from the examining division
24.06.2005Communication of intention to grant the patent
05.07.2005Fee for grant paid
05.07.2005Fee for publishing/printing paid
Parent application(s)   TooltipEP91903963.6  / EP0511306
Opposition(s)Opponent(s)01  13.06.2006  28.06.2006  ADMISSIBLE
Active Biotech AB
Scheelevägen 22, Box 724
220 07 Lund / SE
Opponent's representative
Roques, Sarah Elizabeth, et al, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
 [N/P]
Former [2009/50]
Opponent(s)01  13.06.2006  28.06.2006  ADMISSIBLE
Active Biotech AB
Scheelevägen 22, Box 724
220 07 Lund / SE
Opponent's representative
Roques, Sarah Elizabeth, et al, et al
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Former [2006/29]
Opponent(s)01  13.06.2006   
Active Biotech AB
Scheelevägen 22, Box 724
220 07 Lund / SE
Opponent's representative
Roques, Sarah Elizabeth
J.A. Kemp & Co. 14 South Square Gray's Inn
GB-London WC1R 5JJ / GB
24.07.2006Invitation to proprietor to file observations on the notice of opposition
04.12.2006Reply of patent proprietor to notice(s) of opposition
15.04.2008Date of oral proceedings
30.06.2008Despatch of interlocutory decision in opposition
30.06.2008Despatch of minutes of oral proceedings
17.10.2012Legal effect of interlocutory decision in opposition
04.12.2012Despatch of communication that the patent will be maintained as amended
17.01.2013Fee for printing new specification paid
Appeal following opposition28.08.2008Appeal received No.  T1881/08
06.11.2008Statement of grounds filed
17.10.2012Result of appeal procedure: appeal of the opponent withdrawn
Request for further processing for:04.11.2003Request for further processing filed
04.11.2003Full payment received (date of receipt of payment)
Request granted
18.11.2003Decision despatched
Fees paidRenewal fee
06.03.2001Renewal fee patent year 03
06.03.2001Renewal fee patent year 04
06.03.2001Renewal fee patent year 05
06.03.2001Renewal fee patent year 06
06.03.2001Renewal fee patent year 07
06.03.2001Renewal fee patent year 08
06.03.2001Renewal fee patent year 09
06.03.2001Renewal fee patent year 10
06.03.2001Renewal fee patent year 11
04.02.2002Renewal fee patent year 12
31.01.2003Renewal fee patent year 13
29.01.2004Renewal fee patent year 14
28.01.2005Renewal fee patent year 15
Penalty fee
Additional fee for renewal fee
31.01.200212   M06   Fee paid on   19.06.2002
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT14.09.2005
BE14.09.2005
CH14.09.2005
IT14.09.2005
LI14.09.2005
NL14.09.2005
DK14.12.2005
GR14.12.2005
SE14.12.2005
ES25.12.2005
LU31.01.2006
GB16.01.2011
DE17.01.2011
[2013/31]
Former [2011/35]AT14.09.2005
BE14.09.2005
CH14.09.2005
IT14.09.2005
LI14.09.2005
NL14.09.2005
DK14.12.2005
GR14.12.2005
SE14.12.2005
ES25.12.2005
LU31.01.2006
GB16.01.2011
Former [2007/36]AT14.09.2005
BE14.09.2005
CH14.09.2005
IT14.09.2005
LI14.09.2005
NL14.09.2005
DK14.12.2005
GR14.12.2005
SE14.12.2005
ES25.12.2005
LU31.01.2006
Former [2007/09]AT14.09.2005
BE14.09.2005
CH14.09.2005
LI14.09.2005
NL14.09.2005
DK14.12.2005
GR14.12.2005
SE14.12.2005
ES25.12.2005
LU31.01.2006
Former [2006/34]AT14.09.2005
BE14.09.2005
CH14.09.2005
LI14.09.2005
NL14.09.2005
DK14.12.2005
GR14.12.2005
SE14.12.2005
ES25.12.2005
Former [2006/33]BE14.09.2005
CH14.09.2005
LI14.09.2005
NL14.09.2005
GR14.12.2005
SE14.12.2005
ES25.12.2005
Former [2006/25]BE14.09.2005
CH14.09.2005
LI14.09.2005
NL14.09.2005
GR14.12.2005
SE14.12.2005
Former [2006/22]CH14.09.2005
LI14.09.2005
NL14.09.2005
GR14.12.2005
SE14.12.2005
Former [2006/14]CH14.09.2005
LI14.09.2005
GR14.12.2005
SE14.12.2005
Former [2006/13]SE14.12.2005
Documents cited:Search[XY]WO8909619  (ROTHMAN ULF SVEN ERIK [SE]) [X] 1-5 * page 6, line 1 - page 7, line 22 * * page 10, line 1 - page 12, line 27 * [Y] 6-9;
 [E]WO9104053  (PHARMACIA AB [SE]) [E] 1,2,5 * page 1, line 31 - page 2, line 25 * * page 3, line 19 - line 32 ** page 8, line 7 - line 34; claim - *;
 [Y]  - PETER H. SCHEUBER ET AL., "Skin reactivity of unsensitized monkeys upon challenge with staphylococcal Enterotoxin B: A new approach for investigating the site of toxin action", INFECTION AND IMMUNITY, WASHINGTON US, (198512), vol. 50, no. 3, pages 869 - 876, XP002171579 [Y] 6-9 * abstract * * page 871, column L, paragraph L - column R, paragraph 5 *
 [X]  - PILAR GARCIA-PEÑARRUBIA ET AL., "Selective proliferation of natural killer cells among monocyte-depleted peripheral blood mononuclear cells as a result of stimulation with Staphylococcal enterotoxin B", INFECTION AND IMMUNITY., AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON., US, (198907), vol. 57, no. 7, ISSN 0019-9567, pages 2057 - 2065, XP002164733 [X] 1-5 * abstract * * page 2060, column L, paragraph 2 *
 [X]  - ALAKHOV V Y ET AL, "THE EFFECT OF STAPHYLOCOCCUS AUREUS ENTEROTOXIN A ON PROLIFERATION OF LYMPHOID AND NERVE CELLS", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY,US,ACADEMIC PRESS, (198812), vol. 10, no. 6, ISSN 0885-4513, pages 563 - 567, XP000881483 [X] 1-5 * abstract * * page 564, paragraph 4 - page 565, paragraph 4 *
 [X]  - SHCHEGLOVITOVA, O.N. ET AL., "Effect of Staphylococcus enterotoxin A on the development of Lewis lung carcinoma in mice", BIOLOGICAL ABSTRACTS, (1989), vol. 88, no. 7, Database accession no. 75810, page 639, XP002164734 [X] 1-5 * abstract *
 [X]  - SHCHEGLOVITOVA, O.N. ET AL., "Nonspecific antitumor activity od staphylococcal enterotoxin", BIOLOGICAL ABSTRACTS, (1987), vol. 84, no. 5, Database accession no. 48345, page 685, XP002164735 [X] 1-5 * abstract *
 [X]  - SHCHEGLOVITOVA, O.N. ET AL., "Effect of staphylococcal enterotoxin A-sensitized spleen cells on the metastasizing of mouse Lewis lung carcinoma", BIOLOGICAL ABSTRACTS, (1989), vol. 88, no. 8, Database accession no. 87362, page 700, XP002164736 [X] 1-5 * abstract *
 [X]  - CHRIS D. PLATSOUCAS ET AL., "Immunomodulation of human leukocytes by Staphylococcal Enterotoxin A: Augmentation of natural killer cells and induction of supressor cells", CELLULAR IMMUNOLOGY, (198602), vol. 97, no. 2, pages 371 - 385, XP000990882 [X] 1-5 * abstract * * page 376, paragraph 2 - page 384, paragraph 2 *

DOI:   http://dx.doi.org/10.1016/0008-8749(86)90407-7
    [ ] - EKSP ONKOL, (1989), vol. 11, no. 1, pages 73 - 74
    [ ] - EKSP ONKOL, (1987), vol. 9, no. 1, pages 28 - 30
    [ ] - EKSP ONKOL, (1989), vol. 11, no. 2, pages 54 - 57
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.