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Extract from the Register of European Patents

EP About this file: EP1285918

EP1285918 - C7 Ester substituted taxanes as antitumor agents [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  04.11.2005
Database last updated on 25.09.2024
Most recent event   Tooltip04.11.2005Application deemed to be withdrawnpublished on 21.12.2005  [2005/51]
Applicant(s)For all designated states
Florida State University Research Foundation, Inc.
100 Sliger Building, MC 2763 Tallahassee
Florida 32306-2763 / US
[N/P]
Former [2003/09]For all designated states
Florida State University Research Foundation, Inc.
100 Sliger Building, MC 2763
Tallahassee, Florida 32306-2763 / US
Inventor(s)01 / Holton, Robert A.
7125 Upland Glade
Tallahassee, Florida 32312 / US
 [2003/09]
Representative(s)Maiwald, Walter
Maiwald GmbH
Elisenhof
Elisenstraße 3
80335 München / DE
[N/P]
Former [2003/09]Maiwald, Walter, Dr. Dipl.-Chem.
Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3
80335 München / DE
Application number, filing date01118729.106.08.2001
[2003/09]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1285918
Date:26.02.2003
Language:EN
[2003/09]
Search report(s)(Supplementary) European search report - dispatched on:EP12.11.2001
ClassificationIPC:C07D407/12, A61K31/335, A61P35/00
[2003/09]
CPC:
C07D305/14 (EP); A61P35/00 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/09]
TitleGerman:C7-Estersubstituierte Taxane als Antitumormittel[2003/09]
English:C7 Ester substituted taxanes as antitumor agents[2003/09]
French:Taxanes substitués par ester en C7 utilisés comme agents anticancereux[2003/09]
Examination procedure24.01.2002Amendment by applicant (claims and/or description)
13.08.2003Examination requested  [2003/42]
02.02.2005Despatch of a communication from the examining division (Time limit: M04)
14.06.2005Application deemed to be withdrawn, date of legal effect  [2005/51]
21.07.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2005/51]
Fees paidRenewal fee
13.08.2003Renewal fee patent year 03
12.08.2004Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.08.200505   M06   Not yet paid
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Documents cited:Search[X]US5415869  (STRAUBINGER ROBERT M [US], et al) [X] 1-178 * claims 6,16,22 *;
 [X]WO9513053  (UNIV NEW YORK STATE RES FOUND [US]) [X] 1-178 * claim 8 *;
 [X]WO9744063  (NEUROMEDICA INC [US]) [X] 1-178 * claims 10,16-18 *;
 [X]WO9744026  (NEUROMEDICA INC [US]) [X] 1-178 * claims 6,12 *;
 [X]WO0001366  (NEOPHARM [US], et al) [X] 1-178 * claim 2 *;
 [X]WO0125223  (UNIV NEW YORK STATE RES FOUND [US]) [X] 1-178 * claim 5 *;
 [X]US2001002404  (WEBB NIGEL L [US], et al) [X] 1-178 * page 11 *;
 [E]WO0157013  (UNIV FLORIDA STATE RES FOUND [US]) [E] 1-178 * claims 1-123 *;
 [E]WO0157027  (UNIV FLORIDA STATE RES FOUND [US]) [E] 1-178 * claims 1-177 *;
 [X]  - B.-X. SHI ET AL., "Studies on the Quantitative Structure-activity Relationships of Paclitaxel Analogues", GOADENG XUEXIAO HUAXUE XUEBAO, (2000), vol. 21, no. 3, pages 401 - 406, XP000999959 [X] 1-178 * table 1 *
 [X]  - J. DUBOIS ET AL., "Fluorescent and Biotinylated Analogues of Docetaxel: Synthesis and Biological Evaluation", BIOORG. MED. CHEM., (1995), vol. 3, no. 10, pages 1357 - 1368, XP001022129 [X] 1-178 * Scheme I *

DOI:   http://dx.doi.org/10.1016/0968-0896(95)00115-W
 [X]  - J. DUBOIS ET AL., "Fluorescent and Biotinylated Analogues of Docetaxel: Synthesis and Biological Evaluation", BIOORG. MED. CHEM., (1995), vol. 3, no. 10, pages 1357 - 1368, XP000999888 [X] 1-178 * Scheme 1 *

DOI:   http://dx.doi.org/10.1016/0968-0896(95)00115-W
 [X]  - D. GUENARD ET AL., "Effects of the Hydrophobicity of Taxoids on their Interaction with Tubulin", BIOORG. MED. CHEM., (2000), vol. 8, no. 1, pages 145 - 156, XP001000434 [X] 1-178 * tables 1,4 *

DOI:   http://dx.doi.org/10.1016/S0968-0896(99)00279-5
 [X]  - F. GUERITTE-VOEGELEIN ET AL., "Relationships between the Structue of Taxol Analogues and Their Antimitotic Activity", J. MED. CHEM., (1991), vol. 34, no. 3, pages 992 - 998, XP000650581 [X] 1-178 * tables I,II *

DOI:   http://dx.doi.org/10.1021/jm00107a017
 [X]  - FERLINI, C. ET AL, "Antitumor activity of novel taxanes that act at the same time as cytotoxi agents and P-glycoprotein inhibitors", BR. J. CANCER (2000), 83(12), 1762-1768, XP001029698 [X] 1-178 * table 1 *

DOI:   http://dx.doi.org/10.1054/bjoc.2000.1500
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