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Extract from the Register of European Patents

EP About this file: EP1298207

EP1298207 - Methods of producing protein libraries and selection of proteins from them [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  27.11.2015
Database last updated on 02.11.2024
Most recent event   Tooltip05.02.2016Lapse of the patent in a contracting state
New state(s): ES		published on 09.03.2016  [2016/10]
Applicant(s)For all designated states
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts
Im Neuenheimer Feld 280
69120 Heidelberg / DE
[2010/31]
Former [2003/14]For all designated states
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts
Im Neuenheimer Feld 280
69120 Heidelberg / DE
Inventor(s)01 / Breitling, Frank
Bergheimerstr. 123
69115 Heidelberg / DE
02 / Moldenhauer, Gerhard
Keplerstr. 22
69120 Heidelberg / DE
03 / Poustka, Annemarie
Ladenburger Str. 41
60120 Heidelberg / DE
04 / Kühlwein, Thorsten
Waldstr. 34
68519 Viernheim / DE
05 / Lüttgau, Sandra
Frauenpfad 22
69221 Dossenheim / DE
 [2003/45]
Former [2003/14]01 / Breitling, Frank
Bergheimerstr. 123
69115 Heidelberg / DE
02 / Moldenhauer, Gerhard
Keplerstr. 22
69120 Heidelberg / DE
03 / Poustka, Annemarie
Ladenburger Str. 41
60120 Heidelberg / DE
04 / Kühlwein, Thorsten
Waldstr. 34
68519 Viernheim / DE
Representative(s)Schüssler, Andrea
Kanzlei Huber & Schüssler
Truderinger Strasse 246
81825 München / DE
[2016/01]
Former [2003/14]Schüssler, Andrea, Dr.
Kanzlei Huber & Schüssler Truderinger Strasse 246
81825 München / DE
Application number, filing date01123596.701.10.2001
[2003/14]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report 
No.:EP1298207
Date:02.04.2003
Language:DE
[2003/14]
Type: B1 Patent specification 
No.:EP1298207
Date:04.08.2010
Language:DE
[2010/31]
Type: B2 New European patent specification 
No.:EP1298207
Date:30.12.2015
Language:DE
[2015/53]
Search report(s)(Supplementary) European search report - dispatched on:EP02.05.2002
ClassificationIPC:C12N15/10
[2003/14]
CPC:
C40B40/02 (EP,US); C07K16/30 (EP,US); C07K16/40 (EP,US);
C07K16/461 (EP,US); C12N15/1037 (EP,US); C07K2317/31 (EP,US);
C07K2317/55 (EP,US); C07K2317/622 (EP,US); C07K2319/035 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2016/01]
Former [2003/14]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE,  TR 
TitleGerman:Verfahren zur Herstellung von Protein-Bibliotheken und zur Selektion von Proteinen daraus[2003/14]
English:Methods of producing protein libraries and selection of proteins from them[2003/14]
French:Méthodes pour construire des banques de protéines et pour isoler des protéines de ces banques[2003/14]
Examination procedure24.09.2003Examination requested  [2003/47]
28.07.2005Despatch of a communication from the examining division (Time limit: M04)
02.12.2005Reply to a communication from the examining division
27.09.2007Despatch of a communication from the examining division (Time limit: M04)
23.01.2008Reply to a communication from the examining division
09.06.2009Despatch of a communication from the examining division (Time limit: M04)
09.10.2009Reply to a communication from the examining division
22.01.2010Communication of intention to grant the patent
14.04.2010Fee for grant paid
14.04.2010Fee for publishing/printing paid
Divisional application(s)EP06002567.3  / EP1652920
Opposition(s)Opponent(s)01  04.05.2011  10.05.2011  ADMISSIBLE
Franke & Partner Patent- und Rechtsanwaltskanzlei
Widenmayerstrasse 25
80538 München / DE
 [2013/25]
Former [2011/23]
Opponent(s)01  04.05.2011   
Hards & Franke
Patentanwälte Partnerschaft Widenmayerstraße 25
80538 München / DE
10.06.2011Invitation to proprietor to file observations on the notice of opposition
20.12.2011Reply of patent proprietor to notice(s) of opposition
18.09.2013Legal effect of interlocutory decision in opposition
18.09.2013Date of oral proceedings
27.11.2013Despatch of interlocutory decision in opposition
27.11.2013Despatch of minutes of oral proceedings
28.08.2015Despatch of communication that the patent will be maintained as amended
20.11.2015Fee for printing new specification paid
Fees paidRenewal fee
30.10.2003Renewal fee patent year 03
29.10.2004Renewal fee patent year 04
03.11.2005Renewal fee patent year 05
31.10.2006Renewal fee patent year 06
31.10.2007Renewal fee patent year 07
31.10.2008Renewal fee patent year 08
02.11.2009Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
24.11.200505   M06   Fee paid on   25.04.2006
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
TR04.08.2010
LU01.10.2010
BE31.10.2010
MC31.10.2010
GR05.11.2010
AT01.10.2014
ES02.10.2014
CH31.10.2014
LI31.10.2014
PT01.04.2015
NL01.05.2015
[2016/10]
Former [2015/39]CY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
TR04.08.2010
LU01.10.2010
BE31.10.2010
MC31.10.2010
GR05.11.2010
AT01.10.2014
CH31.10.2014
LI31.10.2014
PT01.04.2015
NL01.05.2015
Former [2015/38]CY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
TR04.08.2010
LU01.10.2010
BE31.10.2010
MC31.10.2010
GR05.11.2010
AT01.10.2014
CH31.10.2014
LI31.10.2014
PT01.04.2015
Former [2015/35]CY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
TR04.08.2010
LU01.10.2010
BE31.10.2010
MC31.10.2010
GR05.11.2010
CH31.10.2014
LI31.10.2014
PT01.04.2015
Former [2015/33]CY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
TR04.08.2010
LU01.10.2010
BE31.10.2010
MC31.10.2010
GR05.11.2010
CH31.10.2014
LI31.10.2014
Former [2015/21]CY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
TR04.08.2010
LU01.10.2010
BE31.10.2010
MC31.10.2010
GR05.11.2010
Former [2011/24]CY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
MC31.10.2010
GR05.11.2010
Former [2011/19]CY04.08.2010
DK04.08.2010
FI04.08.2010
IE04.08.2010
SE04.08.2010
GR05.11.2010
Former [2011/15]CY04.08.2010
FI04.08.2010
SE04.08.2010
GR05.11.2010
Former [2011/13]CY04.08.2010
FI04.08.2010
Former [2011/10]FI04.08.2010
Documents cited:Search[X]US5202238  (FELL JR H PERRY [US], et al) [X] 27-34 * column 13 - column 23; claims 1,2 *;
 [A]US5871907  (WINTER GREGORY PAUL [GB], et al) [A] 1-26* the whole document *;
 [A]US6010884  (GRIFFITHS ANDREW DAVID [GB], et al) [A] 1-26 * claim 15 *;
 [A]WO0005355  (BAYLOR COLLEGE MEDICINE [US]) [A] 1-26 * page 32, line 5 - line 33; example 10 *;
 [A]WO0031236  (LEXICON GENETICS INC [US]) [A] 1-26 * page 27 - page 52 *;
 [X]US6091001  (JAKOBOVITS AYA [US], et al) [X] 27-34 * column 5, line 24 - line 7; examples 1,2; claims 1-4 * * column 6; figures 1-3 *;
 [X]WO0076310  (ABGENIX INC [US], et al) [X] 27-34 * the whole document *;
 [X]US6284536  (MORRISON SHERIE L [US], et al) [X] 27-34 * column 4, line 31 - line 54; examples 1,2; claims 16-21 *
by applicant   - NATURE, vol. 256, pages 495 - 497
    - MOLDENHAUER ET AL., BR J CANCER, (1987), vol. 56, pages 714 - 722
OppositionWO9319172
 WO9920780
 US6091001
    - WATERHOUSE P. ET AL, "Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires", NUCLEIC ACIDS RESEARCH, (1993), vol. 21, no. 9, pages 2265 - 2266
    - HIGUCHI K. ET AL, "Cell display library for gene cloning of variable regions of human antibodies tohepatitis B surface antigen", JOURNAL OF IMMUNOLOGICAL METHODS, (1997), vol. 202, pages 193 - 204
    - O'GORMAN S. ET AL, "Recombinase-Mediated Gene Activation and Site-Specific Integration in Mammalian Cells", SCIENCE, (19910315), vol. 251, pages 1351 - 1355
    - LITTLE M. ET AL, "Of mice and men: hybridoma and recombinant antibodies", REVIEW IMMUNOLOGY TODAY, (200008), vol. 21, no. 8, pages 364 - 370
    - JAMES D. ET AL, Recombinant DNA, COPYRIGHT, (1992), vol. 12, pages 228 - 232
    - JIANG R. ET AL, "Gene targeting: Things go better with Cre", CURRENT BIOLOGY, (1997), vol. 7, no. 5, pages R321 - R323
    - NAGY A., "Cre Recombinase: The Universal Reagent for Genome Tailoring", GENESIS, (2000), no. 26, pages 99 - 109
    - PETERSON M.L. ET AL, "Regulated production of µm and µs mRNA requires linkage of the poly(A) addition sites and is dependent on the length of the µs-µm intron", PROC. NATL. ACAD. SCI. USA, (198612), vol. 83, pages 8883 - 8887
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.