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Extract from the Register of European Patents

EP About this file: EP1261701

EP1261701 - FULL-LENGTH INFECTIOUS cDNA CLONES OF TICK BORNE FLAVIVIRUS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  27.11.2009
Database last updated on 05.10.2024
Most recent event   Tooltip07.10.2011Lapse of the patent in a contracting state
New state(s): CY, TR		published on 09.11.2011  [2011/45]
Applicant(s)For all designated states
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
The National Institute of Health, Office of Technology Transfer, 6011 Executive Boulevard, Suite 325
Rockville, MD 20852 / US
[2009/04]
Former [2002/49]For all designated states
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
c/o National Institutes of Health, Office of Technology Transfer, 6011 Executive Boulevard, Suite 325
Rockville, MD 20852-3804 / US
Inventor(s)01 / PLETNEV, Alexander
12510 Village Square Terrace 302
Rockville, MD 20852 / US
02 / CHANOCK, Robert
7001 Longwood Drive
Bethesda, MD 20817 / US
 [2002/49]
Representative(s)Van Malderen, Joëlle, et al
pronovem - Office Van Malderen
Avenue Josse Goffin 158
1082 Bruxelles / BE
[N/P]
Former [2002/49]Van Malderen, Joelle, et al
Office Van Malderen, Place Reine Fabiola 6/1
1083 Bruxelles / BE
Application number, filing date01910561.809.02.2001
[2002/49]
WO2001US04460
Priority number, dateUS20000181490P10.02.2000         Original published format: US 181490 P
[2002/49]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0159093
Date:16.08.2001
Language:EN
[2001/33]
Type: A2 Application without search report 
No.:EP1261701
Date:04.12.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 16.08.2001 takes the place of the publication of the European patent application.
[2002/49]
Type: B1 Patent specification 
No.:EP1261701
Date:21.01.2009
Language:EN
[2009/04]
Search report(s)International search report - published on:EP14.02.2002
ClassificationIPC:C12N15/00
[2002/49]
CPC:
C07K14/005 (EP,US); A61K39/12 (EP,US); A61P31/14 (EP);
C12N7/00 (EP,US); A61K2039/5254 (EP,US); C12N2770/24122 (EP,US);
C12N2770/24134 (EP,US); C12N2770/24161 (EP,US); C12N2770/24164 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2002/49]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:VOLLSTÄNDIGER, INFEKTIÖSER CDNA KLON DES TICK BORNE FLAVIVIRUS[2002/49]
English:FULL-LENGTH INFECTIOUS cDNA CLONES OF TICK BORNE FLAVIVIRUS[2002/49]
French:CLONES D'ADNc INFECTIEUX DE PLEINE LONGUEUR DE FLAVIVIRUS A TIQUES[2002/49]
Entry into regional phase02.09.2002National basic fee paid 
02.09.2002Designation fee(s) paid 
02.09.2002Examination fee paid 
Examination procedure10.09.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
02.09.2002Amendment by applicant (claims and/or description)
02.09.2002Examination requested  [2002/49]
07.11.2003Despatch of a communication from the examining division (Time limit: M06)
03.05.2004Reply to a communication from the examining division
16.06.2004Despatch of a communication from the examining division (Time limit: M06)
16.12.2004Reply to a communication from the examining division
17.11.2005Despatch of a communication from the examining division (Time limit: M06)
22.06.2006Reply to a communication from the examining division
25.01.2007Despatch of a communication from the examining division (Time limit: M02)
19.03.2007Reply to a communication from the examining division
30.11.2007Communication of intention to grant the patent
31.03.2008Fee for grant paid
31.03.2008Fee for publishing/printing paid
Divisional application(s)EP08103265.8  / EP1978027
Opposition(s)22.10.2009No opposition filed within time limit [2009/53]
Request for further processing for:22.06.2006Request for further processing filed
22.06.2006Full payment received (date of receipt of payment)
Request granted
12.07.2006Decision despatched
Fees paidRenewal fee
02.09.2002Renewal fee patent year 03
23.02.2004Renewal fee patent year 04
22.02.2005Renewal fee patent year 05
27.02.2006Renewal fee patent year 06
27.02.2007Renewal fee patent year 07
25.02.2008Renewal fee patent year 08
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT21.01.2009
CY21.01.2009
DK21.01.2009
FI21.01.2009
NL21.01.2009
TR21.01.2009
IE09.02.2009
LU09.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE21.04.2009
GR22.04.2009
ES02.05.2009
PT22.06.2009
[2011/44]
Former [2011/21]AT21.01.2009
DK21.01.2009
FI21.01.2009
NL21.01.2009
IE09.02.2009
LU09.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE21.04.2009
GR22.04.2009
ES02.05.2009
PT22.06.2009
Former [2010/47]AT21.01.2009
DK21.01.2009
FI21.01.2009
NL21.01.2009
IE09.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE21.04.2009
GR22.04.2009
ES02.05.2009
PT22.06.2009
Former [2010/07]AT21.01.2009
DK21.01.2009
FI21.01.2009
NL21.01.2009
IE09.02.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE21.04.2009
ES02.05.2009
PT22.06.2009
Former [2009/47]AT21.01.2009
DK21.01.2009
FI21.01.2009
NL21.01.2009
CH28.02.2009
LI28.02.2009
MC28.02.2009
SE21.04.2009
ES02.05.2009
PT22.06.2009
Former [2009/46]AT21.01.2009
DK21.01.2009
FI21.01.2009
NL21.01.2009
MC28.02.2009
SE21.04.2009
ES02.05.2009
PT22.06.2009
Former [2009/42]AT21.01.2009
FI21.01.2009
NL21.01.2009
MC28.02.2009
SE21.04.2009
ES02.05.2009
PT22.06.2009
Former [2009/40]AT21.01.2009
FI21.01.2009
NL21.01.2009
SE21.04.2009
ES02.05.2009
PT22.06.2009
Former [2009/37]FI21.01.2009
NL21.01.2009
SE21.04.2009
ES02.05.2009
PT22.06.2009
Former [2009/33]NL21.01.2009
ES02.05.2009
Former [2009/26]NL21.01.2009
Cited inInternational search[A]RU2070929  (SANKT PETERBURGSKIJ NII EPIDEM [RU]) [A] 4,17-22 * abstract *;
 [XY]WO9918216  (US HEALTH [US], et al) [X] 1-16 * the whole document * [Y] 22;
 [A]US6010894  (BARRETT ALAN [US], et al) [A] 4,17-22 * column 2, lines 39-41; table IX *;
 [Y]  - MANDL C W ET AL, "Spontaneous and engineered deletions in the 3' noncoding region of tick-borne encephalitis virus: Construction of highly attenuated mutants of a flavivirus", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (199803), vol. 72, no. 3, ISSN 0022-538X, pages 2132 - 2140, XP002151482 [Y] 22 * the whole document *
 [A]  - LEVKOVICH E N ET AL, "CHARACTERISTICS OF IMMUNOGENESIS IN MONKEYS INFECTED WITH ATTENUATED TICK-BORNE ENCEPHALITIS AND LANGAT VIRUS STRAINS", VOPROSY VIRUSOLOGII, (1981), no. 2, ISSN 0507-4088, pages 160 - 164, XP001018713 [A] 4,17-22 * abstract *
 [A]  - SOKOLOVA E D ET AL, "[Characteristics of neurovirulence, stability, and immunogenicity of attenuated variants of TP-21 Langat virus]. Kharakteristiki neirovirulentnosti, stabil'nosti i immunogennosti oslablennykh variantov virusa Langat TP-21.", VOPROSY VIRUSOLOGII, (1994 SEP-OCT) 39 (5) 220-3., XP001018703 [A] 4,17-22 * abstract *
 [A]  - IACONO-CONNORS L C AND SCHMALJOHN C S, "Cloning and sequence analysis of the genes encoding the nonstructural proteins of Langat virus and comparative analysis with other flaviviruses", VIROLOGY, ACADEMIC PRESS,ORLANDO, US, (199206), vol. 188, no. 2, ISSN 0042-6822, pages 875 - 880, XP002098290 [A] 1-16 * figure 2 *

DOI:   http://dx.doi.org/10.1016/0042-6822(92)90545-Z
 [A]  - MANDL C W ET AL, "SEQUENCE OF THE GENES ENCODING THE STRUCTURAL PROTEINS OF THE LOW-VIRULENCE TICK-BORNE FLAVIVIRUSES LANGAT TP21 AND YELANTSEV", VIROLOGY, (1991), vol. 185, no. 2, ISSN 0042-6822, pages 891 - 895, XP001019192 [A] 1-16 * figure 1 *

DOI:   http://dx.doi.org/10.1016/0042-6822(91)90567-U
 [PX]  - CAMPBELL MARY S ET AL, "Infectious cDNA clones of Langat tick-borne flavivirus that differ from their parent in peripheral neurovirulence.", VIROLOGY, (20000330), vol. 269, no. 1, ISSN 0042-6822, pages 225 - 237, XP002179932 [PX] 1-22 * the whole document *

DOI:   http://dx.doi.org/10.1006/viro.2000.0220
 [PA]  - PLETNEV ALEXANDER G ET AL, "Chimeric Langat/dengue viruses protect mice from heterologous challenge with the highly virulent strains of tick-borne encephalitis virus.", VIROLOGY, (20000815), vol. 274, no. 1, ISSN 0042-6822, pages 26 - 31, XP002179933 [PA] * the whole document *

DOI:   http://dx.doi.org/10.1006/viro.2000.0426
 [T]  - PLETNEV ALEXANDER G, "Infectious cDNA clone of attenuated Langat tick-borne flavivirus (strain E5) and a 3' deletion mutant constructed from it exhibit decreased neuroinvasiveness in immunodeficient mice.", VIROLOGY, (20010410), vol. 282, no. 2, ISSN 0042-6822, pages 288 - 300, XP002179934 [T] * the whole document *

DOI:   http://dx.doi.org/10.1006/viro.2001.0846
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.