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Extract from the Register of European Patents

EP About this file: EP1282616

EP1282616 - HYDROXYPHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATEMENT OF PAIN [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.04.2005
Database last updated on 03.10.2024
Most recent event   Tooltip22.04.2005No opposition filed within time limitpublished on 08.06.2005  [2005/23]
Applicant(s)For all designated states
AstraZeneca AB
151 85 Södertälje / SE
[2003/07]
Inventor(s)01 / BROWN, William AstraZeneca R & D Montreal
7171 Frederick-Banting
St. Laurent, Quebec H4S 1Z9 / CA
02 / WALPOLE, Christopher AstraZeneca R & D Montreal
7171 Frederick-Banting
St. Laurent, Quebec H4S 1Z9 / CA
03 / WEI, Zhongyong AstraZeneca R&D Montreal
7171 Frederick-Banting
St. Laurent, Quebec H4S 1Z9 / CA
 [2003/07]
Application number, filing date01918113.030.03.2001
[2003/07]
WO2001SE00707
Priority number, dateSE2000000120704.04.2000         Original published format: SE 0001207
[2003/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0174804
Date:11.10.2001
Language:EN
[2001/41]
Type: A1 Application with search report 
No.:EP1282616
Date:12.02.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 11.10.2001 takes the place of the publication of the European patent application.
[2003/07]
Type: B1 Patent specification 
No.:EP1282616
Date:16.06.2004
Language:EN
[2004/25]
Search report(s)International search report - published on:SE11.10.2001
ClassificationIPC:C07D401/06, C07D405/06, C07D409/06, C07D211/68, A61K31/4523, A61P25/04, A61P25/00
[2003/07]
CPC:
C07D401/06 (EP,KR,US); A61K31/445 (KR); A61P1/00 (EP);
A61P25/00 (EP); A61P25/02 (EP); A61P25/04 (EP);
C07D211/70 (EP,KR,US); C07D405/06 (EP,KR,US); C07D409/06 (EP,KR,US);
C07D417/06 (EP,KR,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/07]
Extension statesAL04.11.2002
LT04.11.2002
LV04.11.2002
MK04.11.2002
RO04.11.2002
SI04.11.2002
TitleGerman:HYDROXYPHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDDERIVATE ZUR SCHMERZBEKÄMPFUNG[2003/07]
English:HYDROXYPHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATEMENT OF PAIN[2003/07]
French:DERIVES D'HYDROXYPHENYL-PIPERIDINE-4-YLIDENE-METHYL-BENZAMIDE UTILISES COMME ANALGESIQUES[2003/07]
Entry into regional phase04.11.2002National basic fee paid 
04.11.2002Designation fee(s) paid 
04.11.2002Examination fee paid 
Examination procedure12.10.2001Request for preliminary examination filed
International Preliminary Examining Authority: SE
04.11.2002Examination requested  [2003/07]
02.06.2003Despatch of a communication from the examining division (Time limit: M04)
22.09.2003Reply to a communication from the examining division
20.10.2003Communication of intention to grant the patent
13.01.2004Fee for grant paid
13.01.2004Fee for publishing/printing paid
Opposition(s)17.03.2005No opposition filed within time limit [2005/23]
Fees paidRenewal fee
31.03.2003Renewal fee patent year 03
31.03.2004Renewal fee patent year 04
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Cited inInternational search[X]WO9723466  (ASTRA PHARMA INC [CA], et al);
 [X]WO9828275  (ASTRA PHARMA INC [CA], et al);
 [X]WO9933806  (ORTHO MCNEIL PHARM INC [US], et al);
 [X]  - XIAOYAN ZHANG ET AL., "Probes for narcotic receptor mediated phenomena. 26. 1-3 Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands", J. MED. CHEM., (1999), vol. 42, pages 5455 - 5463, XP002943072

DOI:   http://dx.doi.org/10.1021/jm9903895
 [X]  - ZHONG-YONG WEI ET AL., "N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl) benzamide: A novel, exceptionally selective, potent delta opioid receptor agonist with oral biovailability and its analogues", J. MED. CHEM., (2000), vol. 43, pages 3895 - 3905, XP002943073

DOI:   http://dx.doi.org/10.1021/jm000229p
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.