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Extract from the Register of European Patents

EP About this file: EP1259595

EP1259595 - INTEGRIN ANTAGONISTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.02.2008
Database last updated on 03.10.2024
Most recent event   Tooltip13.08.2010Lapse of the patent in a contracting state
New state(s): TR		published on 15.09.2010  [2010/37]
Applicant(s)For all designated states
Immunex Corporation
1201 Amgen Court West
Seattle, WA 91119-3105 / US
[N/P]
Former [2007/07]For all designated states
IMMUNEX CORPORATION
1201 Amgen Court West
Seattle, WA 91119-3105 / US
Former [2006/50]For all designated states
IMMUNEX CORPORATION
1201 Amgen Court West
Seattle, WA 98119-3105 / US
Former [2002/48]For all designated states
IMMUNEX CORPORATION
51 University Street
Seattle Washington 98101 / US
Inventor(s)01 / FANSLOW, William, C., III
404 S.W. 197th Street
Normandy Park, WA 98166 / US
02 / CERRETTI, Douglas, Pat
1607 North 197th Place
Seattle, WA 98133 / US
03 / POINDEXTER, Kurt, Matthew
9247 Interlake Avenue North, Apt. 2
Seattle, WA 98103 / US
04 / BLACK, Roy, Alvin
8062 30th Avenue Northeast
Seattle, WA 98115 / US
 [2002/48]
Representative(s)Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2002/48]Cornish, Kristina Victoria Joy, et al
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date01920133.423.02.2001
[2002/48]
WO2001US05701
Priority number, dateUS20000184865P25.02.2000         Original published format: US 184865 P
[2002/48]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0162905
Date:30.08.2001
Language:EN
[2001/35]
Type: A2 Application without search report 
No.:EP1259595
Date:27.11.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 30.08.2001 takes the place of the publication of the European patent application.
[2002/48]
Type: B1 Patent specification 
No.:EP1259595
Date:04.04.2007
Language:EN
[2007/14]
Search report(s)International search report - published on:EP21.03.2002
ClassificationIPC:C12N9/64, C12N15/57, A61K38/16, A61P35/00, A61P37/00, A61P27/00, A61P17/02
[2002/48]
CPC:
C12N9/6489 (EP,US); A61P1/04 (EP); A61P17/02 (EP);
A61P17/06 (EP); A61P19/02 (EP); A61P19/10 (EP);
A61P27/00 (EP); A61P27/02 (EP); A61P27/06 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P31/04 (EP);
A61P35/00 (EP); A61P35/04 (EP); A61P37/00 (EP);
A61P43/00 (EP); A61P7/02 (EP); A61P9/10 (EP);
C07K14/705 (EP,US); A61K38/00 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2002/48]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:INTEGRIN ANTAGONISTEN[2002/48]
English:INTEGRIN ANTAGONISTS[2002/48]
French:ANTAGONISTES DES INTEGRINES[2002/48]
Entry into regional phase25.09.2002National basic fee paid 
25.09.2002Designation fee(s) paid 
25.09.2002Examination fee paid 
Examination procedure19.09.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
25.09.2002Examination requested  [2002/48]
06.10.2003Despatch of a communication from the examining division (Time limit: M06)
16.04.2004Reply to a communication from the examining division
12.08.2004Despatch of a communication from the examining division (Time limit: M06)
22.02.2005Reply to a communication from the examining division
10.05.2006Despatch of a communication from the examining division (Time limit: M02)
13.07.2006Reply to a communication from the examining division
18.08.2006Communication of intention to grant the patent
14.12.2006Fee for grant paid
14.12.2006Fee for publishing/printing paid
Divisional application(s)EP06026259.9  / EP1803810
Opposition(s)07.01.2008No opposition filed within time limit [2008/11]
Fees paidRenewal fee
12.02.2003Renewal fee patent year 03
12.02.2004Renewal fee patent year 04
14.02.2005Renewal fee patent year 05
14.02.2006Renewal fee patent year 06
14.02.2007Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT04.04.2007
BE04.04.2007
CY04.04.2007
DK04.04.2007
FI04.04.2007
NL04.04.2007
TR04.04.2007
SE04.07.2007
GR05.07.2007
ES15.07.2007
PT04.09.2007
[2010/37]
Former [2009/33]AT04.04.2007
BE04.04.2007
CY04.04.2007
DK04.04.2007
FI04.04.2007
NL04.04.2007
SE04.07.2007
GR05.07.2007
ES15.07.2007
PT04.09.2007
Former [2008/19]AT04.04.2007
BE04.04.2007
DK04.04.2007
FI04.04.2007
NL04.04.2007
SE04.07.2007
GR05.07.2007
ES15.07.2007
PT04.09.2007
Former [2008/09]AT04.04.2007
BE04.04.2007
DK04.04.2007
FI04.04.2007
NL04.04.2007
SE04.07.2007
ES15.07.2007
PT04.09.2007
Former [2008/08]AT04.04.2007
BE04.04.2007
DK04.04.2007
FI04.04.2007
SE04.07.2007
ES15.07.2007
PT04.09.2007
Former [2008/04]AT04.04.2007
BE04.04.2007
FI04.04.2007
SE04.07.2007
ES15.07.2007
PT04.09.2007
Former [2007/50]AT04.04.2007
FI04.04.2007
SE04.07.2007
ES15.07.2007
PT04.09.2007
Former [2007/48]FI04.04.2007
SE04.07.2007
ES15.07.2007
PT04.09.2007
Former [2007/47]ES15.07.2007
Cited inInternational search[DA]WO9923228  (IMMUNEX CORP [US], et al) [DA] 1-42 * page 6, paragraph 2 * * page 8, paragraph 2 *;
 [DA]WO9936549  (IMMUNEX CORP [US], et al) [DA] 1-42 * page 4, line 24 - line 30 * * page 7, line 25 - page 8, line 26 *;
 [AD]WO9941388  (IMMUNEX CORP [US], et al) [AD] 1-42 * the whole document *;
 [PX]WO0043493  (HUMAN GENOME SCIENCES INC [US], et al) [PX] 1-9,11-29,31,32,34-42 * page 13, line 3 * * page 17, line 6 - line 7 * * page 196, line 31 - page 204, line 33 * * page 227 - page 234 * * examples 10,39,41-43,49 *;
 [E]WO0174857  (BRISTOL MYERS SQUIBB CO [US], et al) [E] 1-18,20,27,28,30-42 * page 4, line 26 - page 6, line 16 * * page 7, line 11 - page 8, line 26 ** page 14, line 17 - line 34; example 12 *;
 [X]  - SCHLUESENER HERMANN J, "The disintegrin domain of ADAM 8 enhances protection against rat experimental autoimmune encephalomyelitis, neuritis and uveitis by a polyvalent autoantigen vaccine.", JOURNAL OF NEUROIMMUNOLOGY, (19980701), vol. 87, no. 1-2, ISSN 0165-5728, pages 197 - 202, XP000926791 [X] 1-3,16,17,26 * page 199 - page 201; figure 2A *

DOI:   http://dx.doi.org/10.1016/S0165-5728(98)00080-0
    [DXAY] - NATH DEEPA ET AL, "Interaction of metargidin (ADAM-15) with alphavbeta3 and alpha5beta1 integrins on different haemopoietic cells.", JOURNAL OF CELL SCIENCE, LONDON GB, (199902), vol. 112, no. 4, ISSN 0021-9533, pages 579 - 587, XP002186267 [DX] 1-3,7-18,27,31,33-41 * the whole document, especially page 586, column 1 * [A] 35-42 [Y] 4
 [X]  - ZHANG XI-PING ET AL, "Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3.", JOURNAL OF BIOLOGICAL CHEMISTRY, WASHINGTON US, (19980327), vol. 273, no. 13, ISSN 0021-9258, pages 7345 - 7350, XP002186268 [X] 1-3,9-18,27,31,33 * the whole document, especially page 7349, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1074/jbc.273.13.7345
 [Y]  - SHEU J-R ET AL, "Inhibition of angiogenesis in vitro and in vivo: comparison of the relative activities of triflavin, an Arg-Gly-Asp-containing peptide and anti-alphavbeta3 integrin monoclonal antibody", BBA - GENERAL SUBJECTS, ELSEVIER SCIENCE PUBLISHERS, NL, (19971020), vol. 1336, no. 3, ISSN 0304-4165, pages 445 - 454, XP004276037 [Y] 4 * abstract *

DOI:   http://dx.doi.org/10.1016/S0304-4165(97)00057-3
 [Y]  - TSELEPIS VICKY H ET AL, "An RGD to LDV motif conversion within the disintegrin kistrin generates an integrin antagonist that retains potency but exhibits altered receptor specificity: Evidence for a functional equivalence of acidic integrin-binding motifs", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (1997), vol. 272, no. 34, ISSN 0021-9258, pages 21341 - 21348, XP002149905 [Y] 4 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.272.34.21341
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.