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Extract from the Register of European Patents

EP About this file: EP1274693

EP1274693 - METHOD FOR PRODUCING 2,5-DIKETOPIPERAZINES, 2,5-DIKETOPIPERAZINES, DIPEPTIDES AND THE USE THEREOF [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  14.05.2010
Database last updated on 03.09.2024
Most recent event   Tooltip14.05.2010Withdrawal of applicationpublished on 16.06.2010  [2010/24]
Applicant(s)For all designated states
Evonik Degussa GmbH
Rellinghauser Straße 1-11
45128 Essen / DE
[N/P]
Former [2008/32]For all designated states
Evonik Degussa GmbH
Rellinghauser Strasse 1-11
45128 Essen / DE
Former [2007/45]For all designated states
Evonik Degussa GmbH
Bennigsenplatz 1
40474 Düsseldorf / DE
Former [2007/08]For all designated states
Degussa GmbH
Bennigsenplatz 1
40474 Düsseldorf / DE
Former [2003/03]For all designated states
Degussa AG
Bennigsenplatz 1
40474 Düsseldorf / DE
Inventor(s)01 / DRAUZ, Karlheinz
Zur Marienruhe 13
63579 Freigericht / DE
02 / KNAUP, Günter
Friedhofstrasse 8
63486 Bruchköbel / DE
 [2003/03]
Application number, filing date01927786.223.03.2001
[2003/03]
WO2001EP03322
Priority number, dateDE2000101987920.04.2000         Original published format: DE 10019879
[2003/03]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report
No.:WO0181321
Date:01.11.2001
Language:DE
[2001/44]
Type: A1 Application with search report 
No.:EP1274693
Date:15.01.2003
Language:DE
The application published by WIPO in one of the EPO official languages on 01.11.2001 takes the place of the publication of the European patent application.
[2003/03]
Search report(s)International search report - published on:EP01.11.2001
ClassificationIPC:C07D241/08, C07K5/12, C07K5/06
[2003/03]
CPC:
C07D241/08 (EP,US); C07K5/06086 (EP,US); C07K5/06191 (EP,US);
C07K5/12 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/03]
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON 2,5-DIKETOPIPERAZINEN, 2,5-DIKETOPIPERAZINE, DIPEPTIDE UND DEREN VERWENDUNG[2003/03]
English:METHOD FOR PRODUCING 2,5-DIKETOPIPERAZINES, 2,5-DIKETOPIPERAZINES, DIPEPTIDES AND THE USE THEREOF[2003/03]
French:PROCEDE DE PREPARATION DE 2,3-DICETOPIPERAZINES, 2,5-DICETOPIPERAZINES, DIPEPTIDES ET LEUR UTILISATION[2003/03]
Entry into regional phase09.10.2002National basic fee paid 
09.10.2002Designation fee(s) paid 
09.10.2002Examination fee paid 
Examination procedure06.10.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
09.10.2002Examination requested  [2003/03]
28.04.2006Despatch of a communication from the examining division (Time limit: M04)
01.06.2006Reply to a communication from the examining division
18.07.2008Despatch of a communication from the examining division (Time limit: M04)
20.11.2008Reply to a communication from the examining division
05.05.2010Application withdrawn by applicant  [2010/24]
Fees paidRenewal fee
26.02.2003Renewal fee patent year 03
27.02.2004Renewal fee patent year 04
08.03.2005Renewal fee patent year 05
15.03.2006Renewal fee patent year 06
14.03.2007Renewal fee patent year 07
13.03.2008Renewal fee patent year 08
13.03.2009Renewal fee patent year 09
26.03.2010Renewal fee patent year 10
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[A]EP0365992  (ABBOTT LAB [US]) [A] 1 * page 46, line 29 * * und Seite 49, Schema 2 *;
 [A]WO9114378  (NUTRASWEET CO [US]) [A] 1 * page 5, lines 4-6 * * page 10, lines 4-16; example 3 *;
 [A]US5503852  (STEINER SOLOMON S [US], et al) [A] 7* example 1 *;
 [XA]  - I.J. FRIGERIO ET AL., "Ring Current Shielding and Molecular Motions in Piperazine-2,5-diones", AUST.J.CHEM., (1982), vol. 35, no. 8, pages 1609 - 1614, XP001013047 [X] 1,2,4,5 * page 1613, paragraph 4 * * page 1613, paragraph 4 * [A] 3,6-11
 [XA]  - C.A. LOVELETTE ET AL., "A convenient Synthesis of 1-Substituted 2,5(4H)-Piperazinediones", J.HETEROCYCL.CHEM., (1986), vol. 23, pages 229-229 - 231, XP001008649 [X] 1,2,4,5 * page 230, paragraph 3 * * page 231; example 4A * * page 231; example 4A * [A] 3,6-11

DOI:   http://dx.doi.org/10.1002/jhet.5570230147
 [A]  - S. KLUTCHKO ET AL., "Synthesis of Novel Angiotensin Converting Enzyme Inhibitor Quinapril and Related Compounds", J.MED.CHEM., (1986), vol. 29, no. 10, pages 1953 - 1961, XP001008772 [A] 1 * Seite 1956: Herstellung von (37) und (39) unter Schema II; und Seite 1960, Methode H *

DOI:   http://dx.doi.org/10.1021/jm00160a026
 [A]  - D.E. NITECKI ET AL., "A Simple Route to Sterically Pure Diketopiperazines", J.ORG.CHEM., (1968), vol. 33, no. 2, pages 864 - 866, XP001008667 [A] 1 * page 864, column 1 * * Preparation of 2,5-Diketopiperazines:; page 864, column 2 *

DOI:   http://dx.doi.org/10.1021/jo01266a091
 [A]  - S. STEINBERG, "Diketopiperazine Formation During Investigations of Amino Acid Racemisation in Dipeptides", SCIENCE, (1981), vol. 213, pages 544 - 545, XP001013307 [A] 5 * column W *

DOI:   http://dx.doi.org/10.1126/science.213.4507.544
 [A]  - E. ABDERHALDEN ET AL, "Über die Entstehung von Diketopiperazinen aus Polypeptiden unter verschiedenen Bedingungen", HOPPE-SEYLER'S Z.PHYSIOL.CHEM., (1924), vol. 139, pages 152 - 161, XP001008646 [A] 6 * Variante e):; page 166 - page 167 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.