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Extract from the Register of European Patents

EP About this file: EP1292313

EP1292313 - METHODS FOR TREATING HEPATITIS DELTA VIRUS INFECTION WITH BETA-L-2' DEOXY-NUCLEOSIDES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  15.07.2005
Database last updated on 16.11.2024
Most recent event   Tooltip14.12.2007Lapse of the patent in a contracting state
New state(s): PT		published on 16.01.2008  [2008/03]
Applicant(s)For all designated states
Idenix (Cayman) Limited
Walker Secretaries, Walker House
Grand Cayman / KY
[N/P]
Former [2003/12]For all designated states
Idenix (Cayman) Limited
Walker Secretaries, Walker House
Grand Cayman / KY
Inventor(s)01 / SOMMADOSSI, Jean-Pierre
5075 Greystone Way
Birmingham, AL 3524 / US
02 / BRYANT, Martin, L.
65 Hickory Lane
Carlisle, MA 01741 / US
 [2003/12]
Representative(s)Hallybone, Huw George, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2003/12]Hallybone, Huw George, et al
Carpmaels and Ransford, 43 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date01937785.229.05.2001
[2003/12]
WO2001US17301
Priority number, dateUS20000207538P26.05.2000         Original published format: US 207538 P
[2003/12]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0191737
Date:06.12.2001
Language:EN
[2001/49]
Type: A2 Application without search report 
No.:EP1292313
Date:19.03.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 06.12.2001 takes the place of the publication of the European patent application.
[2003/12]
Type: B1 Patent specification 
No.:EP1292313
Date:08.09.2004
Language:EN
[2004/37]
Search report(s)International search report - published on:EP30.05.2002
ClassificationIPC:A61K31/706, A61K31/7064, A61K31/7068, A61K31/7072, A61K31/7076, A61K31/708, A61P31/12, A61K31/70
[2003/12]
CPC:
A61K45/06 (EP,US); A61K31/7076 (EP,KR,US); A61K31/7068 (EP,US);
A61K31/7072 (EP,US); A61K31/708 (EP,US); A61P31/12 (EP);
A61P31/20 (EP) (-)
C-Set:
A61K31/7068, A61K2300/00 (EP,US);
A61K31/7072, A61K2300/00 (US,EP);
A61K31/7076, A61K2300/00 (US,EP);
A61K31/708, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/12]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RO11.12.2002
SINot yet paid
TitleGerman:METHODEN ZUR BEHANDLUNG VON DELTA HEPATITIS VIRUS INFEKTIONEN MIT BETA-L-2' DEOXY-NUCLEOSIDEN[2003/12]
English:METHODS FOR TREATING HEPATITIS DELTA VIRUS INFECTION WITH BETA-L-2' DEOXY-NUCLEOSIDES[2003/12]
French:PROCEDES DE TRAITEMENT DE L'INFECTION PAR LE VIRUS DELTA DE L'HEPATITE PAR BETA-L-2' DEOXY-NUCLEOSIDES[2003/12]
Entry into regional phase11.12.2002National basic fee paid 
11.12.2002Designation fee(s) paid 
11.12.2002Examination fee paid 
Examination procedure11.12.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
12.12.2002Examination requested  [2003/12]
26.02.2003Despatch of a communication from the examining division (Time limit: M06)
02.10.2003Reply to a communication from the examining division
12.02.2004Communication of intention to grant the patent
30.06.2004Fee for grant paid
30.06.2004Fee for publishing/printing paid
Opposition(s)09.06.2005No opposition filed within time limit [2005/35]
Request for further processing for:02.10.2003Request for further processing filed
02.10.2003Full payment received (date of receipt of payment)
Request granted
17.10.2003Decision despatched
Fees paidRenewal fee
11.12.2002Renewal fee patent year 03
13.05.2004Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT08.09.2004
FI08.09.2004
NL08.09.2004
DK08.12.2004
SE08.12.2004
PT08.02.2005
CY29.05.2005
[2008/03]
Former [2007/20]AT08.09.2004
FI08.09.2004
NL08.09.2004
DK08.12.2004
SE08.12.2004
CY29.05.2005
Former [2006/14]AT08.09.2004
FI08.09.2004
NL08.09.2004
DK08.12.2004
SE08.12.2004
Former [2005/46]AT08.09.2004
FI08.09.2004
DK08.12.2004
SE08.12.2004
Former [2005/13]AT08.09.2004
FI08.09.2004
SE08.12.2004
Former [2005/11]FI08.09.2004
SE08.12.2004
Former [2005/10]SE08.12.2004
Cited inInternational search[X]WO0009531  (NORIVIO PHARMACEUTICALS LTD [FR], et al) [X] 1-65 * the whole document *;
 [A]  - BEERS M.H.; BERKOW R. (EDS.)., MERCK MANUAL OF DIAGNOSIS AND THERAPY (17th ed.), WHITEHOUSE STATION N.J., MERCK RESEARCH LABORATORIES, (1999), 236240, XP002187299 [A] 1-65 * page 379, column 2, paragraph 2 - page 380, column 1, paragraph 1 *
 [X]  - MARCHAND, ARNAUD ET AL, "Stereospecific synthesis of unnatural.beta.-L-enantiomers of 2-chloroadenine pentofuranonucleoside derivatives", J. CHEM. SOC., PERKIN TRANS. 1 (1999), (16), 2249-2254, XP001052612 [X] 1,2,22,24,25,45,46 * abstract * * page 2251, column 1, paragraph 2 - column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1039/a904380b
 [X]  - VON JANTA-LIPINSKI, MARTIN ET AL, "Newly Synthesized L-Enantiomers of 3'-Fluoro-Modified ss-2'-Deoxyribonucleoside 5'-Triphosphates Inhibit Hepatitis B DNA Polymerases But Not the Five Cellular DNA Polymerases.alpha.,.beta.,.gamma.,.delta., and.epsilon. Nor HIV-1 Reverse Transcriptase", J. MED. CHEM. (1998), 41(12), 2040-2046, XP001052614 [X] 1,10,17,18,22,24,33,40,41,45,54,61,62 * abstract *

DOI:   http://dx.doi.org/10.1021/jm9704210
 [X]  - VERRI, ANNALISA ET AL, "Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogs", BIOCHEM. J. (1997), 328(1), 317-320, XP001058113 [X] 1,10,17,18,22,24,33,40,41,45,54,61,62 * the whole document *
 [X]  - LIN T-S ET AL, "Synthesis of Several Pyrimidine l-Nucleoside Analogues as Potential Antiviral Agents", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (19950123), vol. 51, no. 4, ISSN 0040-4020, pages 1055 - 1068, XP004104973 [X] 1,10,16,22,24,33,39,45,54,60 * abstract * * page 1060, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/0040-4020(94)00997-9
 [A]  - GAUBERT, GILLES ET AL, "Unnatural enantiomers of 5-azacytidine analogs: syntheses and enzymic properties", EUR. J. MED. CHEM. (2000), 35(11), 1011-1019, XP004227516 [A] 1-65 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0223-5234(00)01184-3
 [A]  - LIN, TAI-SHUN ET AL, "Design and Synthesis of 2',3'-Dideoxy-2',3'-didehydro-.beta.-L- cytidine (.beta.-L-d4C) and 2',3'-Dideoxy-2',3'-didehydro-.beta.-L-5- fluorocytidine (.beta.-L-Fd4C), Two Exceptionally Potent Inhibitors of Human Hepatitis B Virus ( HBV ) and Potent Inhibitors of Human Immunodeficiency Virus (HIV) in", J. MED. CHEM. (1996), 39(9), 1757-9, XP001052613 [A] 1-65 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm950836q
 [A]  - MANSOUR, T. S. ET AL, "Stereochemical aspects of the anti-HCMV activity of cytidine nucleoside analogs", ANTIVIRAL CHEM. CHEMOTHER. (1995), 6(3), 138-42, XP001058115 [A] 1-65 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.