Extract from the Register of European Patents

EP About this file: EP1391509

EP1391509 - TRANSFORMED SILKWORM PRODUCING HUMAN COLLAGEN [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.06.2008
Database last updated on 28.03.2026
Most recent event   Tooltip27.06.2008Application deemed to be withdrawnpublished on 30.07.2008  [2008/31]
Applicant(s)For all designated states
Japan Science and Technology Agency
1-8, Honcho 4-chome Kawaguchi-shi
Saitama 332-0012 / JP
For all designated states
Hiroshima Industrial Promotion Organization
7-47, Senda-machi, 3-chome, Naka-ku Hiroshima-shi
Hiroshima 730-0052 / JP
For all designated states
Terumo Kabushiki Kaisha
44-1, Hatagaya 2-chome, Shibuya-ku
Tokyo 151-0072 / JP
For all designated states
KOKEN CO., Ltd.
14-3, Mejiro 3-chome
Toshima-ku
Tokyo 171-0031 / JP
For all designated states
NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES
1-2 Kannondai 2-chome Tsukuba-shi
Ibaraki 305-8602 / JP
[N/P]
Former [2004/41]For all designated states
Japan Science and Technology Agency
1-8, Honcho 4-chome
Kawaguchi-shi, Saitama 332-0012 / JP
For all designated states
Hiroshima Industrial Promotion Organization
7-47, Senda-machi, 3-chome, Naka-ku
Hiroshima-shi, Hiroshima 730-0052 / JP
For all designated states
TERUMO KABUSHIKI KAISHA
44-1, Hatagaya 2-chome, Shibuya-ku
Tokyo 151-0072 / JP
For all designated states
KOKEN CO., LTD.
14-3, Mejiro 3-chome
Toshima-ku, Tokyo 171-0031 / JP
For all designated states
National Institute of Agrobiological Sciences
1-2 Kannondai 2-chome
Tsukuba-shi, Ibaraki 305-8602 / JP
Former [2004/09]For all designated states
JAPAN SCIENCE AND TECHNOLOGY CORPORATION
1-8, Honcho 4-chome
Kawaguchi-shi, Saitama 332-0012 / JP
For all designated states
Hiroshima Industrial Promotion Organization
7-47, Senda-machi, 3-chome, Naka-ku
Hiroshima-shi, Hiroshima 730-0052 / JP
For all designated states
TERUMO KABUSHIKI KAISHA
44-1, Hatagaya 2-chome, Shibuya-ku
Tokyo 151-0072 / JP
For all designated states
KOKEN CO., LTD.
14-3, Mejiro 3-chome
Toshima-ku, Tokyo 171-0031 / JP
For all designated states
National Institute of Agrobiological Sciences
1-2 Kannondai 2-chome
Tsukuba-shi, Ibaraki 305-8602 / JP
Inventor(s)01 / YOSHIZATO, Katsutoshi
22-13, Hachihonmatsu-minami 7-chome
Higashihiroshima-shi, Hiroshima 739-0144 / JP
02 / TOMITA, Masahiro
1-19, Saijyo-chuo 5-chome
Higashihiroshima-shi, Hiroshima 739-0025 / JP
03 / SATOU, Tsutomu
23-6, Nishigaoka 1-chome
Kita-ku, Tokyo / JP
04 / MORI, Hajime
27-1, Osanaikawara-machi, Kita-ku
Kyoto-shi, Kyoto 603-8131 / JP
05 / TAMURA, Toshiki
2, Ooowashi 1-chome
Tsukuba-shi, Ibaraki 305-0851 / JP
06 / ADACHI, Takahiro
4215-1, Shitami, Saijyou-cho
Higashihiroshima-shi, Hiroshima 739-0044 / JP
07 / MUNETSUNA, Hiroto
4-1, Kanpoda, Kurose-cho
Kamo-gun, Hiroshima / JP
 [2004/09]
Representative(s)Webber, Philip Michael
Dehns
St Bride's House
10 Salisbury Square
London
EC4Y 8JD / GB
[N/P]
Former [2004/09]Webber, Philip Michael
Frank B. Dehn & Co., 179 Queen Victoria Street
London EC4V 4EL / GB
Application number, filing date01938587.111.06.2001
[2004/09]
WO2001JP04906
Priority number, dateJP2001012015518.04.2001         Original published format: JP 2001120155
[2004/09]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO02086119
Date:31.10.2002
Language:EN
[2002/44]
Type: A1 Application with search report 
No.:EP1391509
Date:25.02.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 31.10.2002 takes the place of the publication of the European patent application.
[2004/09]
Search report(s)International search report - published on:JP31.10.2002
(Supplementary) European search report - dispatched on:EP16.11.2004
ClassificationIPC:C12N15/09, A01K67/04, C12N9/02
[2004/09]
CPC:
C12N15/8509 (EP,US); A01K67/61 (EP,US); A01K67/68 (EP,US);
A01K2217/05 (EP,US); A01K2267/01 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/09]
TitleGerman:MENSCHLICHES KOLLAGEN PRODUZIERENDE TRANSFORMIERTE SEIDENRAUPE[2004/09]
English:TRANSFORMED SILKWORM PRODUCING HUMAN COLLAGEN[2004/09]
French:VER A SOIE TRANSFORME PRODUISANT DU COLLAGENE HUMAIN[2004/09]
Entry into regional phase17.11.2003Translation filed 
17.11.2003National basic fee paid 
17.11.2003Search fee paid 
17.11.2003Designation fee(s) paid 
17.11.2003Examination fee paid 
Examination procedure20.11.2001Request for preliminary examination filed
International Preliminary Examining Authority: JP
17.11.2003Examination requested  [2004/09]
19.09.2005Despatch of a communication from the examining division (Time limit: M06)
21.07.2006Reply to a communication from the examining division
04.09.2006Despatch of a communication from the examining division (Time limit: M06)
27.06.2007Reply to a communication from the examining division
26.07.2007Despatch of a communication from the examining division (Time limit: M06)
06.02.2008Application deemed to be withdrawn, date of legal effect  [2008/31]
13.03.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/31]
Request for further processing for:27.06.2007Request for further processing filed
27.06.2007Full payment received (date of receipt of payment)
Request granted
13.07.2007Decision despatched
21.07.2006Request for further processing filed
21.07.2006Full payment received (date of receipt of payment)
Request granted
04.08.2006Decision despatched
Fees paidRenewal fee
17.11.2003Renewal fee patent year 03
29.06.2004Renewal fee patent year 04
23.06.2005Renewal fee patent year 05
26.06.2006Renewal fee patent year 06
25.06.2007Renewal fee patent year 07
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Documents cited:Search[T]   TOMITA M ET AL: "Transgenic silkworms produce recombinant human type III procollagen in cocoons", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, vol. 21, no. 1, January 2003 (2003-01-01), pages 52 - 56, XP002975379, ISSN: 1087-0156 [T] 1-24

DOI:   http://dx.doi.org/10.1038/nbt771
 [T]   WURM FLORIAN M: "Human therapeutic proteins from silkworms.", NATURE BIOTECHNOLOGY. JAN 2003, vol. 21, no. 1, January 2003 (2003-01-01), pages 34 - 35, XP002303198, ISSN: 1087-0156 [T] 1-24

DOI:   http://dx.doi.org/10.1038/nbt0103-34
 [A]   DATABASE EMBL EBI, HINXTON, CAMBS UK; 1 February 2000 (2000-02-01), MITA K: "Bombyx Mori cDNA", XP002303199, Database accession no. EM_EST:AV403044 [A] 18,19,23,24 * column A *
 [A]   LEES J F ET AL: "THE ROLE OF CYSTEINE RESIDUES IN THE FOLDING AND ASSOCIATION OF THECOOH-TERMINAL PROPEPTIDE OF TYPES I AND III PROCOLLAGEN", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 269, no. 39, 30 September 1994 (1994-09-30), pages 24354 - 24360, XP002071356, ISSN: 0021-9258 [A] * the whole document *
International search[Y]   YAMAO M. ET AL: "Gene targeting in the silkworm by use of a baculovirus", GENES AND DEVELOPMENT, vol. 13, no. 5, 1999, pages 511 - 516, XP002945820 [Y]
 [Y]   TOSHIKI T. ET AL: "Germline transformation of the silkworm Bombyx mori L. using a piggyBac transposon-derived vector", NATURE BIOTECHNOLOGY, vol. 18, no. 1, January 2000 (2000-01-01), pages 81 - 84, XP002945821 [Y]

DOI:   http://dx.doi.org/10.1038/71978
 [Y]   TARJA H. ET AL: "Cloning, baculovirus expression and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha2beta2 tetramer with the protein disulfide-isomerase/beta subunit", PROC. NATL. ACAD. SCI. USA, vol. 92, 1995, pages 4427 - 4431, XP002945822 [Y]

DOI:   http://dx.doi.org/10.1073/pnas.92.10.4427
 [Y]   HOPKINSON I. ET AL: "The complete cDNA derived sequence of the rat prolyl 4-hydroxylase alpha subunit", GENE, vol. 149, 1994, pages 391 - 392, XP002945823 [Y]

DOI:   http://dx.doi.org/10.1016/0378-1119(94)90188-0
 [XP]   YOSHISATO K.: "Kumikae-tai konchuu riyou e no teigen", SANSHI KONCHUU KEN SHIRYOU, vol. 28, March 2001 (2001-03-01), pages 93 - 95, XP002945824 [XP]
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