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EP About this file: EP1305635

EP1305635 - METHODS TO IDENTIFY COMPOUNDS THAT MODULATE RAGE [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 20.07.2007 Database last updated on 19.10.2024
Most recent event Tooltip	11.09.2009	Lapse of the patent in a contracting state New state(s): TR	published on 14.10.2009 [2009/42]
Applicant(s)	For all designated states Trans Tech Pharma, Inc. Suite 110, 4170 Mendenhall Oaks Parkway High Point, NC 27265 / US
	[2006/37]
Former [2003/18]	For all designated states Trans Tech Pharma, Inc. Suite 110, 4170 Mendenhall Oaks Parkway High Point, NC 27265 / US
Inventor(s)	01 / SHAHBAZ, Manouchehr 8504 Rosedale Drive Oak Ridge, NC 27310 / US
	[2003/18]
Representative(s)	Boff, James Charles, et al Phillips & Leigh 5 Pemberton Row London EC4A 3BA / GB
	[N/P]
Former [2005/10]	Boff, James Charles, et al Phillips & Leigh, 5 Pemberton Row London EC4A 3BA / GB
Former [2003/18]	Farwell, William Robert, et al PHILLIPS & LEIGH 5 Pemberton Row London EC4A 3BA / GB
Application number, filing date	01941698.1	30.05.2001
	[2003/18]
	WO2001US17447
Priority number, date	US20000207342P	30.05.2000 Original published format: US 207342 P
	US20010799152	05.03.2001 Original published format: US 799152
	[2003/18]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO0192892
	Date:	06.12.2001
	Language:	EN
	[2001/49]
	Type:	A2 Application without search report
	No.:	EP1305635
	Date:	02.05.2003
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 06.12.2001 takes the place of the publication of the European patent application.
	[2003/18]
	Type:	B1 Patent specification
	No.:	EP1305635
	Date:	13.09.2006
	Language:	EN
	[2006/37]
Search report(s)	International search report - published on:	EP	27.02.2003
Classification	IPC:	G01N33/68	[2003/18]
	CPC:	G01N33/566 (EP,US); A61P13/12 (EP); A61P15/10 (EP); A61P25/28 (EP); A61P29/00 (EP); A61P3/10 (EP); (+) A61P35/00 (EP); A61P43/00 (EP); G01N2333/70503 (EP,US) (-)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2003/18]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
	SI	Not yet paid
Title	German:	VERFAHREN ZUR IDENTIFIZIERUNG VON RAGE-MODULIERENDEN VERBINDUNGEN	[2003/18]
	English:	METHODS TO IDENTIFY COMPOUNDS THAT MODULATE RAGE	[2003/18]
	French:	PROCEDES D'IDENTIFICATION DE COMPOSES QUI MODULENT RAGE	[2006/03]
	Former [2003/18]	PROCEDES D'IDENTIFICATION DE COMPOSES QUI MODULENT LE RECEPTEUR RAGE
Entry into regional phase	25.02.2002	National basic fee paid
	25.02.2002	Designation fee(s) paid
	25.02.2002	Examination fee paid
Examination procedure	19.12.2001	Request for preliminary examination filed International Preliminary Examining Authority: EP
	28.02.2002	Examination requested [2003/18]
	21.02.2003	Amendment by applicant (claims and/or description)
	12.11.2004	Despatch of a communication from the examining division (Time limit: M06)
	20.05.2005	Reply to a communication from the examining division
	16.01.2006	Communication of intention to grant the patent
	25.04.2006	Fee for grant paid
	25.04.2006	Fee for publishing/printing paid
Divisional application(s)	EP06019068.3 / EP1724589
Opposition(s)	14.06.2007	No opposition filed within time limit [2007/34]
Fees paid	Renewal fee
	28.07.2003	Renewal fee patent year 03
	13.05.2004	Renewal fee patent year 04
	12.05.2005	Renewal fee patent year 05
	23.03.2006	Renewal fee patent year 06
	Penalty fee
	Additional fee for renewal fee
	31.05.2003	03 M06 Fee paid on 28.07.2003
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	CY	13.09.2006
	FI	13.09.2006
	NL	13.09.2006
	TR	13.09.2006
	GR	14.12.2006
	PT	26.02.2007
	[2009/42]
Former [2009/37]	CY	13.09.2006
	FI	13.09.2006
	NL	13.09.2006
	GR	14.12.2006
	PT	26.02.2007
Former [2008/20]	FI	13.09.2006
	NL	13.09.2006
	GR	14.12.2006
	PT	26.02.2007
Former [2008/04]	FI	13.09.2006
	NL	13.09.2006
	PT	26.02.2007
Former [2007/36]	FI	13.09.2006
	IT	13.09.2006
	NL	13.09.2006
	PT	26.02.2007
Former [2007/26]	FI	13.09.2006
	NL	13.09.2006
	PT	26.02.2007
Former [2007/19]	FI	13.09.2006
	NL	13.09.2006
Former [2007/10]	FI	13.09.2006
Cited in	International search	[XY]WO9739121 (SCHERING AG [DE]) [X] 28-42 * claims 1-40 * [Y] 1-27,43-58;
		[XY]WO9918987 (UNIV COLUMBIA [US]) [X] 28-42 * examples 1,3; claims 6-14,37-67,70-74 * [Y] 1-27,43-58;
		[XY]WO0020458 (UNIV COLUMBIA [US]) [X] 28-42 * page 8, line 8 - line 18; claims 1-57 * * page 11, line 20 - line 36 * * page 13, line 28 - page 14, line 16 * * examples 1,2 * [Y] 1-27,43-58;
		[YD] - NEEPER M. ET AL., "Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.", J. BIOL. CHEM., (19920725), vol. 267, no. 21, pages 14998 - 15004, XP002036214 [YD] 1-58 * the whole document * DOI: http://dx.doi.org/10.1016/S0021-9258(18)42138-2
		[XDY] - PARK L. ET AL., "Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts.", NATURE MED., (199809), vol. 4, no. 9, pages 1025 - 1031, XP002923420 [XD] 28-42 * the whole document * [Y] 1-27,43-58 DOI: http://dx.doi.org/10.1038/2012
		[Y] - KISLINGER T. ET AL., "N-epsilon-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression.", J. BIOL. CHEM., (19991029), vol. 274, no. 44, pages 31740 - 31749, XP002217809 [Y] 1-58 * the whole document * DOI: http://dx.doi.org/10.1074/jbc.274.44.31740
		[XDY] - HOFMANN M.A. ET AL., "RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.", CELL, (19990625), vol. 97, pages 889 - 901, XP002935188 [XD] 28-42 * the whole document * [Y] 1-27,43-58 DOI: http://dx.doi.org/10.1016/S0092-8674(00)80801-6
		[Y] - SCHMIDT A.M. ET AL., "Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis.", CIRC. RES., (1999), vol. 84, pages 489 - 497, XP002909514 [Y] 1-58 * the whole document *

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