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EP1287146

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Extract from the Register of European Patents

EP About this file: EP1287146

EP1287146 - COLD SENSITIVE MUTANT DNA POLYMERASES [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 23.06.2006 Database last updated on 25.09.2024
Most recent event Tooltip	05.12.2008	Lapse of the patent in a contracting state New state(s): CY	published on 07.01.2009 [2009/02]
Applicant(s)	For all designated states Washington University 1 Brookings Drive St. Louis, MO 63130 / US
	[N/P]
Former [2003/10]	For all designated states WASHINGTON UNIVERSITY 1 Brookings Drive St. Louis, MO 63130 / US
Inventor(s)	01 / BARNES, Wayne, M. 11 Princeton Avenue University City, MO 63130 / US
	02 / KERMEKCHIEV, Milko, B. 6665 West Park Avenue St. Louis, MO 63139 / US
	[2003/10]
Representative(s)	Maiwald GmbH Elisenhof Elisenstraße 3 80335 München / DE
	[N/P]
Former [2003/10]	Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3 80335 München / DE
Application number, filing date	01944300.1	05.06.2001
	[2003/10]
	WO2001US18236
Priority number, date	US20000587856	06.06.2000 Original published format: US 587856
	[2003/10]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO0194562
	Date:	13.12.2001
	Language:	EN
	[2001/50]
	Type:	A2 Application without search report
	No.:	EP1287146
	Date:	05.03.2003
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 13.12.2001 takes the place of the publication of the European patent application.
	[2003/10]
	Type:	B1 Patent specification
	No.:	EP1287146
	Date:	17.08.2005
	Language:	EN
	[2005/33]
Search report(s)	International search report - published on:	EP	30.05.2002
Classification	IPC:	C12N15/55, C12N15/10, C12N15/66, C12N9/12, C12Q1/68	[2003/10]
	CPC:	C12N9/1252 (EP,US); C12Q1/686 (EP,US)
	C-Set:	C12Q1/686, C12Q2549/107, C12Q2527/101, C12Q2521/101 (EP,US)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2003/10]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
	SI	Not yet paid
Title	German:	KÄLTEEMPFINDLICHE DNA-POLYMERASEMUTANTEN	[2003/10]
	English:	COLD SENSITIVE MUTANT DNA POLYMERASES	[2003/10]
	French:	POLYMERASES D'ADN MUTANTES SENSIBLES AU FROID	[2003/10]
Biological material	This application mentions deposited biological material, check the file for details
Entry into regional phase	05.12.2002	National basic fee paid
	05.12.2002	Designation fee(s) paid
	05.12.2002	Examination fee paid
Examination procedure	03.01.2002	Request for preliminary examination filed International Preliminary Examining Authority: EP
	05.12.2002	Examination requested [2003/10]
	30.01.2004	Despatch of a communication from the examining division (Time limit: M06)
	03.08.2004	Reply to a communication from the examining division
	07.02.2005	Communication of intention to grant the patent
	07.06.2005	Fee for grant paid
	07.06.2005	Fee for publishing/printing paid
Opposition(s)	18.05.2006	No opposition filed within time limit [2006/30]
Fees paid	Renewal fee
	12.06.2003	Renewal fee patent year 03
	14.06.2004	Renewal fee patent year 04
	14.06.2005	Renewal fee patent year 05
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	CY	17.08.2005
	FI	17.08.2005
	IT	17.08.2005
	NL	17.08.2005
	TR	17.08.2005
	DK	17.11.2005
	GR	17.11.2005
	SE	17.11.2005
	PT	17.01.2006
	[2009/02]
Former [2007/36]	FI	17.08.2005
	IT	17.08.2005
	NL	17.08.2005
	TR	17.08.2005
	DK	17.11.2005
	GR	17.11.2005
	SE	17.11.2005
	PT	17.01.2006
Former [2006/51]	FI	17.08.2005
	NL	17.08.2005
	TR	17.08.2005
	DK	17.11.2005
	GR	17.11.2005
	SE	17.11.2005
	PT	17.01.2006
Former [2006/26]	FI	17.08.2005
	NL	17.08.2005
	DK	17.11.2005
	GR	17.11.2005
	SE	17.11.2005
	PT	17.01.2006
Former [2006/25]	FI	17.08.2005
	NL	17.08.2005
	GR	17.11.2005
	SE	17.11.2005
	PT	17.01.2006
Former [2006/14]	FI	17.08.2005
	NL	17.08.2005
	GR	17.11.2005
	SE	17.11.2005
Former [2006/13]	FI	17.08.2005
	SE	17.11.2005
Cited in	International search	[A]WO9206188 (BARNES WAYNE M [US]) [A] * the whole document *;
		[A]WO9426766 (BARNES WAYNE M [US]) [A] * the whole document *;
		[A]WO9641010 (NEXSTAR PHARMACEUTICALS INC [US], et al) [A] * the whole document *;
		[A]WO9840496 (PERKIN ELMER CORP [US]) [A] * Mutation E681G;;; claims 1-15 *;
		[A]EP0902035 (HOFFMANN LA ROCHE [CH]) [A] * page 3, line 44 - line 51 * * page 6, line 21 - line 28; claims 1-26 *;
		[A] - NAGANO KOHJI ET AL, "fcsA29 mutation is an allele of polA gene of Escherichia coli.", BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, (199902), vol. 63, no. 2, ISSN 0916-8451, pages 427 - 429, XP002190820 [A] * the whole document * DOI: http://dx.doi.org/10.1271/bbb.63.427
		[A] - BARNES W M, "THE FIDELITY OF TAQ POLYMERASE CATALYZING PCR IS IMPROVED BY AN N-TERMINAL DELETION", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, (199204), vol. 112, ISSN 0378-1119, pages 29 - 35, XP002915507 [A] * the whole document * DOI: http://dx.doi.org/10.1016/0378-1119(92)90299-5
		[A] - BARNES W M, "PCR AMPLIFICATION OF UP TO 35-KB DNA WITH HIGH FIDELITY AND HIGH YIELD FROM LAMBDA BACTERIOPHAGE TEMPLATES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (19940301), vol. 91, ISSN 0027-8424, pages 2216 - 2220, XP002030133 [A] * the whole document * DOI: http://dx.doi.org/10.1073/pnas.91.6.2216
		[A] - KELLOGG ET AL, "TaqStart Antibody", BIOTECHNIQUES, EATON PUBLISHING, NATICK, US, (1994), vol. 16, no. 6, ISSN 0736-6205, pages 1134 - 1137, XP002103159 [A] * the whole document *
		[A] - HORTON R M ET AL, "AMPLIGREASE: HOT START PCR USING PETROLEUM JELLY", BIOTECHNIQUES, EATON PUBLISHING, NATICK, US, (1994), vol. 16, no. 1, ISSN 0736-6205, pages 42 - 43, XP000420681 [A] * the whole document *
		[A] - HANSEN H ET AL, "AUTOMATED HOT START PCR USING MINERAL OIL AND PARAFFIN WAX", BIOTECHNIQUES, EATON PUBLISHING, NATICK, US, (1993), vol. 14, no. 1, ISSN 0736-6205, pages 30 - 34, XP000331736 [A] * the whole document *
		[A] - CADWELL R AND JOYCE G ET AL, "Randomization of genes by PCR mutagenesis", PCR METHODS AND APPLICATIONS, COLD SPRING HARBOR, NY, US, (1992), vol. 2, ISSN 1054-9803, pages 28 - 33, XP002087462 [A] * the whole document *
		[A] - CHOU Q ET AL, "PREVENTION OF PRE-PCR MIS-PRIMING AND PRIMER DIMERIZATION IMPROVES LOW-COPY-NUMBER AMPLIFICATIONS", NUCLEIC ACIDS RESEARCH, (1992), vol. 20, no. 7, ISSN 0305-1048, pages 1717 - 1723, XP002190821 [A] * the whole document *
		[A] - B. HÉBERT ET AL., "Increased PCR sensitivity by using paraffin wax as a reaction mix overlay", MOL. AND CELL. PROBES, ACADEMIC PRESS, NEW YORK, US, (1993), vol. 7, pages 249 - 252, XP002190822 [A] * the whole document * DOI: http://dx.doi.org/10.1006/mcpr.1993.1036

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