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Extract from the Register of European Patents

EP About this file: EP1257547

EP1257547 - 1,3-DISUBSTITUTED PYRROLIDINES AS ALPHA-2-ADRENOCEPTOR ANTAGONISTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  28.11.2008
Database last updated on 05.10.2024
Most recent event   Tooltip09.07.2010Lapse of the patent in a contracting state
New state(s): LU		published on 11.08.2010  [2010/32]
Applicant(s)For:BE  CH  CY  DE  DK  ES  FI  FR  GB  GR  IE  IT  LI  LU  MC  NL  PT  SE  TR 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
[N/P]
Former [2008/04]For:BE  CH  CY  DE  DK  ES  FI  FR  GB  GR  IE  IT  LI  LU  MC  NL  PT  SE  TR 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
Former [2003/11]For:BE  CH  CY  DE  DK  ES  FI  FR  GB  GR  IE  IT  LU  MC  NL  PT  SE  TR  LI 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
Former [2003/10]For:BE  CH  CY  DE  DK  ES  FI  FR  GB  GR  IE  IT  LU  MC  NL  PT  SE  TR  LI 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1235 Vienna / AT
Former [2002/47]For:BE  CH  CY  DE  DK  ES  FI  FR  GB  GR  IE  IT  LU  MC  NL  PT  SE  TR  LI 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis-Erfindungen Verwaltungsgesellschaft m.b.H.
Brunnerstrasse 59
1230 Wien / AT
Inventor(s)01 / SEILER, Max, Peter
Bockrainweg 16
CH-4125 Riehen / CH
02 / NOZULAK, Joachim
In der Ziegelei 1
79423 Heitersheim / DE
 [2002/47]
Representative(s)Gros, Florent
Novartis AG
4002 Basel / CH
[2002/47]
Application number, filing date01946858.626.01.2001
[2002/47]
WO2001EP00861
Priority number, dateGB2000000210028.01.2000         Original published format: GB 0002100
[2002/47]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0155132
Date:02.08.2001
Language:EN
[2001/31]
Type: A1 Application with search report 
No.:EP1257547
Date:20.11.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 02.08.2001 takes the place of the publication of the European patent application.
[2002/47]
Type: B1 Patent specification 
No.:EP1257547
Date:23.01.2008
Language:EN
[2008/04]
Search report(s)International search report - published on:EP02.08.2001
ClassificationIPC:C07D405/06, C07D401/06, C07D207/06, C07D405/12, C07D413/06, C07D403/06, A61K31/4025, A61P25/18, A61P25/24
[2002/47]
CPC:
C07D207/08 (EP,KR,US); A61P15/00 (EP); A61P15/10 (EP);
A61P25/00 (EP); A61P25/02 (EP); A61P25/16 (EP);
A61P25/18 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/26 (EP); A61P25/28 (EP); A61P25/30 (EP);
A61P27/00 (EP); A61P27/06 (EP); A61P3/10 (EP);
A61P43/00 (EP); C07D207/09 (EP,KR,US); C07D401/06 (EP,KR,US);
C07D403/06 (EP,KR,US); C07D405/06 (EP,KR,US); C07D405/08 (EP,KR,US);
C07D413/06 (EP,KR,US); C07D417/06 (EP,KR,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2002/47]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RO21.06.2002
SI21.06.2002
TitleGerman:1,3 - DISUBSTITUIERTE PYRROLIDINE ALS ALPHA -2- ADRENOZEPTORANTAGONISTEN[2002/47]
English:1,3-DISUBSTITUTED PYRROLIDINES AS ALPHA-2-ADRENOCEPTOR ANTAGONISTS[2002/47]
French:PYRROLIDINES 1,3-DISUBSTITUEES EN TANT QU'ANTAGONISTES DU RECEPTEUR ADRENERGIQUE ALPHA 2[2002/47]
Entry into regional phase21.06.2002National basic fee paid 
21.06.2002Designation fee(s) paid 
21.06.2002Examination fee paid 
Examination procedure13.06.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
21.06.2002Amendment by applicant (claims and/or description)
21.06.2002Examination requested  [2002/47]
26.03.2004Despatch of a communication from the examining division (Time limit: M06)
19.01.2005Reply to a communication from the examining division
24.04.2006Despatch of a communication from the examining division (Time limit: M06)
13.12.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
23.02.2007Reply to a communication from the examining division
30.07.2007Communication of intention to grant the patent
10.12.2007Fee for grant paid
10.12.2007Fee for publishing/printing paid
Opposition(s)24.10.2008No opposition filed within time limit [2009/01]
Request for further processing for:23.02.2007Request for further processing filed
23.02.2007Full payment received (date of receipt of payment)
Request granted
13.04.2007Decision despatched
19.01.2005Request for further processing filed
19.01.2005Full payment received (date of receipt of payment)
Request granted
03.02.2005Decision despatched
Fees paidRenewal fee
31.01.2003Renewal fee patent year 03
02.02.2004Renewal fee patent year 04
31.01.2005Renewal fee patent year 05
31.01.2006Renewal fee patent year 06
31.01.2007Renewal fee patent year 07
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY23.01.2008
DK23.01.2008
FI23.01.2008
LU26.01.2008
IE28.01.2008
MC31.01.2008
SE23.04.2008
[2010/32]
Former [2009/33]CY23.01.2008
DK23.01.2008
FI23.01.2008
IE28.01.2008
MC31.01.2008
SE23.04.2008
Former [2009/08]DK23.01.2008
FI23.01.2008
IE28.01.2008
MC31.01.2008
SE23.04.2008
Former [2008/46]DK23.01.2008
FI23.01.2008
MC31.01.2008
SE23.04.2008
Former [2008/39]FI23.01.2008
MC31.01.2008
Cited inInternational search[XY]WO9218475  (UPJOHN CO [US]) [X] 1,5,7 * example 78; claim 1 * * examples S-18,,S-39; table 1 * [Y] 6,8-10;
 [A]US5185364  (DEBERNARDIS JOHN F [US], et al) [A] 1,5-10* example 49 *;
 [X]WO0003714  (WATERS ROSS NICHOLAS [SE], et al) [X] 1,5,7 * claim 1 *;
 [X]  - CHEMICAL ABSTRACTS, (1965), vol. 62, no. 4, Database accession no. 3995b, XP002164442 [X] 1,3,5,7 * abstract *
    [ ] - A.V.EL'TSOV ET AL, "N-Aralkyl derivatives of phenylpyrrolidines", ZH. OBSHCH. KHIM., (1964), vol. 34, no. 10, pages 3344 - 3351
 [AY]  - AHN, KYO HAN ET AL, "N-Substituted 3-arylpyrrolidines: potent and selective ligands at the serotonin 1A receptor", BIOORG. MED. CHEM. LETT. (1999), 9(10), 1379-1384, XP004164896 [A] 1 * Examples 3, 8a, 8b, 8c, Table 1 * [Y] 6,8-10

DOI:   http://dx.doi.org/10.1016/S0960-894X(99)00201-2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.