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EP1315729
European procedure
Extract from the Register of European Patents
EP About this file: EP1315729
| EP1315729 - COMPOUNDS IN THE FORM OF HOMODIMERIC OR HETERODIMERIC PRODRUGS; PROCESS FOR OBTAINING THESE PRODRUGS AND THEIR ACCEPTABLE PHARMACEUTICAL SALTS AND USE OF COMPOUNDS IN THE TREATMENT OF PHOSPHODIESTERASES-MEDIATED DISEASES OR DYSFUNCTION [Right-click to bookmark this link] | |||
| Former [2003/23] | COMPOUNDS IN THE FORM OF HOMODIMERIC, HETERODIMERIC AND/OR HOMO AND HETEROMULTIMERIC PRO-DRUGS; PROCESS FOR OBTAINING THESE PRO-DRUGS AND THEIR ACCEPTABLE PHARMACEUTICAL SALTS AND USE OF COMPOUNDS IN THE TREATMENT OF PHOSPHODIESTERASIS-MEDIATED DISEASES OR DYSFUNCTION | ||
| [2008/02] | Status | No opposition filed within time limit Status updated on 14.11.2008 Database last updated on 03.06.2024 | Most recent event Tooltip | 10.07.2009 | Lapse of the patent in a contracting state New state(s): CY | published on 12.08.2009 [2009/33] | Applicant(s) | For all designated states Cristália Produtos Químicos Farmacêuticos Ltda. 363 Paoletti Av., Itapira 13970-000 Sao Paulo, SP / BR | For all designated states De Castro, Pacheco Ogari D. Pedro I St., 109, Itapira CEP-13970-000 Sao Paulo, SP / BR | [2008/02] |
| Former [2003/23] | For all designated states Cristalia Produtos Quimicos e Farmaceuticos Ltda Paoletti Av.,363, Itapira CEP-13970-000 Sao Paulo, SP / BR | ||
| For all designated states De Castro, Pacheco Ogari D. Pedro I St., 109, Itapira CEP-13970-000 Sao Paulo, SP / BR | Inventor(s) | 01 /
RUSSO, Elisa, Mannochio de Souza Dos IpêS St., 118, Jardim Santa Marta,Itapira CEP-13970-000 Sao Paulo, SP / BR | 02 /
RUSSO, Valter, Freire, Torres Dos IpêS St., 118, Jardim Santa Marta, Itapira CEP-13970-000 Sao Paulo, SP / BR | [2004/11] |
| Former [2003/23] | 01 /
DE SOUZA, Russo, Elisa, Mannochio Dos IpêS St., 118, Jardim Santa Marta,Itapira CEP-13970-000 Sao Paulo, SP / BR | ||
| 02 /
TORRES RUSSO, Valter, Freire Dos IpêS St., 118, Jardim Santa Marta, Itapira CEP-13970-000 Sao Paulo, SP / BR | Representative(s) | Alves Moreira, Pedro Raul César Ferreira (Herd.), Lda. Rua do Patrocinio, 94 1399-019 Lisbon / PT | [N/P] |
| Former [2007/51] | Alves Moreira, Pedro Raul César Ferreira (Herd.), Lda. Rua do Patrocinio, 94 1399-019 Lisbon / PT | ||
| Former [2003/23] | Alves Moreira, Pedro Rua do Patrocinio, 94 1399-019 Lisboa / PT | Application number, filing date | 01953709.1 | 07.08.2001 | [2003/23] | WO2001BR00096 | Priority number, date | BR20000033863 | 08.08.2000 Original published format: BR 0033863 | [2003/23] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO0212241 | Date: | 14.02.2002 | Language: | EN | [2002/07] | Type: | A1 Application with search report | No.: | EP1315729 | Date: | 04.06.2003 | Language: | EN | The application published by WIPO in one of the EPO official languages on 14.02.2002 takes the place of the publication of the European patent application. | [2003/23] | Type: | B1 Patent specification | No.: | EP1315729 | Date: | 09.01.2008 | Language: | EN | [2008/02] | Search report(s) | International search report - published on: | US | 14.02.2002 | (Supplementary) European search report - dispatched on: | EP | 26.05.2004 | Classification | IPC: | C07D519/00, A61K31/519, A61P15/12 | [2007/35] | CPC: |
C07D487/04 (EP,US);
A61K47/56 (EP,US);
A61P15/10 (EP);
A61P15/12 (EP)
|
| Former IPC [2004/28] | C07D519/00, A61K31/519, A61P15/12, // (C07D519/00, 487:00, 487:00) | ||
| Former IPC [2003/23] | C07D487/04 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2003/23] | Extension states | AL | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | RO | Not yet paid | SI | Not yet paid | Title | German: | VERBINDUNGEN IN FORM HOMODIMERER ODER HETERODIMERER PRODRUGS; VERFAHREN ZUR HERSTELLUNG DIESER PRODRUGS UND DEREN PHARMAKOLOGISCH VERTRÄGLICHEN SALZEN UND VERWENDUNG VON VERBINDUNGEN IN DER BEHANDLUNG VON PHOSPHODIESTERASE VERMITTELTEN KRANKHEITEN UND FUNKTIONSSTÖRUNGEN | [2008/02] | English: | COMPOUNDS IN THE FORM OF HOMODIMERIC OR HETERODIMERIC PRODRUGS; PROCESS FOR OBTAINING THESE PRODRUGS AND THEIR ACCEPTABLE PHARMACEUTICAL SALTS AND USE OF COMPOUNDS IN THE TREATMENT OF PHOSPHODIESTERASES-MEDIATED DISEASES OR DYSFUNCTION | [2008/02] | French: | COMPOSES SOUS FORME DE PROMEDICAMENTS HOMODIMERIQUES OU HETERODIMERIQUES; PROCEDES PERMETTANT D'OBTENIR CES PROMEDICAMENTS AINSI QUE LEURS SELS PHARMACEUTIQUEMENT ACCEPTABLES; UTILISATION DE CES COMPOSES DANS LE TRAITEMENT DU DYSFONCTIONNEMENT ET/OU DES MALADIES INDUI | [2008/02] |
| Former [2003/23] | VERBINDUNGEN IN FORM HOMODIMERER, HETERODIMERER UND/ODER HOMO- UND HETEROMULTIMERER PRO-DRUGS; VERFAHREN ZUR HERSTELLUNG DIESER PRO-DRUGS UND DEREN PHARMAKOLOGISCH VERTRÄGLICHEN SALZEN UND VERWENDUNG VON VERBINDUNGEN IN DER BEHANDLUNG VON PHOSPHODIESTERASE VERMITTELTEN KRANKHEITEN UND FUNKTIONSSTÖRUNGEN | ||
| Former [2003/23] | COMPOUNDS IN THE FORM OF HOMODIMERIC, HETERODIMERIC AND/OR HOMO AND HETEROMULTIMERIC PRO-DRUGS; PROCESS FOR OBTAINING THESE PRO-DRUGS AND THEIR ACCEPTABLE PHARMACEUTICAL SALTS AND USE OF COMPOUNDS IN THE TREATMENT OF PHOSPHODIESTERASIS-MEDIATED DISEASES OR DYSFUNCTION | ||
| Former [2003/23] | COMPOSES SOUS FORME DE PROMEDICAMENTS HOMODIMERIQUES, HETERODIMERIQUES ET/OU HOMO ET HETEROMULTIMERIQUES; PROCEDES PERMETTANT D'OBTENIR CES PROMEDICAMENTS AINSI QUE LEURS SELS PHARMACEUTIQUEMENT ACCEPTABLES; UTILISATION DE CES COMPOSES DANS LE TRAITEMENT DU DYSFONCTIONNEMENT ET/OU DES MALADIES INDUI | Entry into regional phase | 21.02.2003 | National basic fee paid | 21.02.2003 | Search fee paid | 21.02.2003 | Designation fee(s) paid | 21.02.2003 | Examination fee paid | Examination procedure | 04.02.2002 | Request for preliminary examination filed International Preliminary Examining Authority: US | 21.02.2003 | Examination requested [2003/23] | 27.07.2004 | Amendment by applicant (claims and/or description) | 18.08.2004 | Despatch of a communication from the examining division (Time limit: M04) | 16.12.2004 | Reply to a communication from the examining division | 26.04.2006 | Despatch of a communication from the examining division (Time limit: M06) | 24.10.2006 | Reply to a communication from the examining division | 23.01.2007 | Despatch of a communication from the examining division (Time limit: M04) | 23.05.2007 | Reply to a communication from the examining division | 16.08.2007 | Communication of intention to grant the patent | 20.11.2007 | Fee for grant paid | 20.11.2007 | Fee for publishing/printing paid | Opposition(s) | 10.10.2008 | No opposition filed within time limit [2008/51] | Fees paid | Renewal fee | 24.11.2003 | Renewal fee patent year 03 | 02.03.2004 | Renewal fee patent year 04 | 07.04.2005 | Renewal fee patent year 05 | 05.06.2006 | Renewal fee patent year 06 | 12.06.2007 | Renewal fee patent year 07 | Penalty fee | Additional fee for renewal fee | 31.08.2003 | 03 M06 Fee paid on 24.11.2003 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CY | 09.01.2008 | MC | 31.08.2008 | [2009/33] |
| Former [2009/18] | MC | 31.08.2008 | Documents cited: | Search | [A]WO9312143 (KABI PHARMACIA AB [SE]) [A] 2-11,13-31* page 8, line 2 - page 8, line 8; claims 1,12 *; | [Y]WO9428902 (PFIZER LTD [GB], et al) [Y] 2-11,13-31 * claims 1,5 *; | [Y] - CHRISTIAANS, J. AND TIMMERMANN H., "Cardiovascular hybrid drugs: combination of more than one pharmacological property in one single molecule", EUROP. J. PHARM. SCI., (1996), vol. 4, no. 1, pages 1 - 22, XP002279965 [Y] 2-11,13-31 * part 1 (Introduction) and 2 (Classification of hybrid molecules) * DOI: http://dx.doi.org/10.1016/0928-0987(95)00029-1 | [A] - MAHFOUZ N M ET AL, "Metronidazole twin ester prodrugs: synthesis, physicochemical properties, hydrolysis kinetics and antigiardial activity", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, (19980901), vol. 33, no. 9, ISSN 0223-5234, pages 675 - 683, XP004140822 [A] 2-11,13-31 * part 1 (Introduction) and 4 (Conclusion) * DOI: http://dx.doi.org/10.1016/S0223-5234(98)80026-3 | [A] - STEFANO DI A ET AL, "Dimeric L-Dopa Derivatives as Potential Prodrugs", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, (2001), vol. 11, ISSN 0960-894X, pages 1085 - 1088, XP002233238 [A] 2-11,13-31 * page 1085 * DOI: http://dx.doi.org/10.1016/S0960-894X(01)00140-8 | International search | [X]WO9964033 (ADVANCED MEDICINE INC [US], et al); | [Y]US6051576 (ASHTON PAUL [US], et al) |