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Extract from the Register of European Patents

EP About this file: EP1307469

EP1307469 - NUCLEIC ACID BINDING COMPOUNDS CONTAINING PYRAZOLO 3,4-D PYRIMIDINE ANALOGUES OF PURIN-2,6-DIAMINE AND THEIR USES [Right-click to bookmark this link]
Former [2003/19]NUCLEIC ACID BINDING COMPOUNDS CONTAINING PYRAZOLO[3,4-D]PYRIMIDINE ANALOGUES OF PURIN-2,6-DIAMINE AND THEIR USES
[2007/45]
StatusNo opposition filed within time limit
Status updated on  28.11.2008
Database last updated on 25.09.2024
Most recent event   Tooltip19.08.2011Lapse of the patent in a contracting state
New state(s): GR
published on 21.09.2011  [2011/38]
Applicant(s)For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  CH  CY  DE  DK  ES  FI  FR  GB  GR  IE  IT  LI  LU  MC  NL  PT  SE  TR 
F. Hoffmann-La Roche AG
Grenzacherstrasse 24
4070 Basle / CH
[2008/04]
Former [2003/19]For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  CH  CY  DE  DK  ES  FI  FR  GB  GR  IE  IT  LI  LU  MC  NL  PT  SE  TR 
F. HOFFMANN-LA ROCHE AG
Grenzacherstrasse 24
4070 Basle / CH
Inventor(s)01 / SEELA, Frank
Gutenbergstrasse 44
49076 Osnabrueck / DE
02 / BERGMANN, Frank
Faltergatter 5
82393 Iffeldorf / DE
03 / VON DER ELTZ, Herbert
In der Au 21
82362 Weilheim / DE
04 / HEINDL, Dieter
Waldschmidtstrasse 1
82327 Tutzing / DE
05 / SEIDEL, Christoph
Ammerstrasse 39
82362 Weilheim / DE
06 / BECHER, Georg
4413 Feldspar Ct., Apt 1B
Greensboro, NC 27409 / US
 [2003/23]
Former [2003/19]01 / SEELA, Frank
Gutenbergstrasse 44
49076 Osnabrueck / DE
02 / BERGMANN, Frank
Faltergatter 5
82393 Iffeldorf / DE
03 / VON DER ELTZ, Herbert
In der Au 21
82362 Weilheim / DE
04 / HEINDL, Dieter
Waldschmidtstrasse 1
82327 Tutzing / DE
05 / SEIDEL, Christoph
Ammerstrasse 39
82362 Weilheim / DE
06 / BECHER, Georg
Spindelstrasse 24
49080 Osnabrueck / DE
Representative(s)Herren, Barbara, et al
Roche Diagnostics AG
Patent Department
Forrenstrasse
6343 Rotkreuz / CH
[N/P]
Former [2008/33]Herren, Barbara, et al
Roche Diagnostics AG Forrentstrasse
6343 Rotkreuz / CH
Application number, filing date01956576.131.07.2001
[2003/19]
WO2001EP08850
Priority number, dateEP2000011681603.08.2000         Original published format: EP 00116816
EP2001010943824.04.2001         Original published format: EP 01109438
[2003/19]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0212263
Date:14.02.2002
Language:EN
[2002/07]
Type: A1 Application with search report 
No.:EP1307469
Date:07.05.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 14.02.2002 takes the place of the publication of the European patent application.
[2003/19]
Type: B1 Patent specification 
No.:EP1307469
Date:23.01.2008
Language:EN
[2008/04]
Search report(s)International search report - published on:EP14.02.2002
ClassificationIPC:C07H19/16, C07H21/00, C12Q1/68
[2003/19]
CPC:
C07H21/00 (EP,US); C07H19/16 (EP,US); Y10T436/143333 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/19]
TitleGerman:NUKLEINSÄUREBINDENDE VERBINDUNGEN MIT PYRAZOLO 3,4-D PYRIMIDINANALOGEN VON PURIN-2,6-DIAMIN UND IHRE VERWENDUNG[2007/45]
English:NUCLEIC ACID BINDING COMPOUNDS CONTAINING PYRAZOLO 3,4-D PYRIMIDINE ANALOGUES OF PURIN-2,6-DIAMINE AND THEIR USES[2007/45]
French:COMPOSES DE FIXATION D'ACIDES NUCLEIQUES CONTENANT DES ANALOGUES PYRAZOLO 3,4-D PYRIMIDINE DE PURINE 2,6-DIAMINE ET LEURS UTILISATIONS[2007/45]
Former [2003/19]NUKLEINSÄUREBINDENDE VERBINDUNGEN MIT PYRAZOLO[3,4-D]PYRIMIDINANALOGEN VON PURIN-2,6-DIAMIN UND IHRE VERWENDUNG
Former [2003/19]NUCLEIC ACID BINDING COMPOUNDS CONTAINING PYRAZOLO[3,4-D]PYRIMIDINE ANALOGUES OF PURIN-2,6-DIAMINE AND THEIR USES
Former [2003/19]COMPOSES DE FIXATION D'ACIDES NUCLEIQUES CONTENANT DES ANALOGUES PYRAZOLO[3,4-D]PYRIMIDINE DE PURINE 2,6-DIAMINE ET LEURS UTILISATIONS
Entry into regional phase03.03.2003National basic fee paid 
03.03.2003Designation fee(s) paid 
03.03.2003Examination fee paid 
Examination procedure07.02.2002Request for preliminary examination filed
International Preliminary Examining Authority: EP
03.03.2003Examination requested  [2003/19]
11.07.2006Despatch of a communication from the examining division (Time limit: M04)
02.08.2006Reply to a communication from the examining division
23.11.2006Despatch of a communication from the examining division (Time limit: M04)
08.02.2007Reply to a communication from the examining division
28.03.2007Despatch of a communication from the examining division (Time limit: M04)
22.05.2007Reply to a communication from the examining division
10.08.2007Communication of intention to grant the patent
06.12.2007Fee for grant paid
06.12.2007Fee for publishing/printing paid
Opposition(s)24.10.2008No opposition filed within time limit [2009/01]
Fees paidRenewal fee
14.07.2003Renewal fee patent year 03
09.07.2004Renewal fee patent year 04
08.07.2005Renewal fee patent year 05
10.07.2006Renewal fee patent year 06
04.07.2007Renewal fee patent year 07
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See the Register of the Unified Patent Court for opt-out data
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Lapses during opposition  TooltipBE23.01.2008
CY23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
TR23.01.2008
SE23.04.2008
PT23.06.2008
GR31.07.2008
IE31.07.2008
LU31.07.2008
MC31.07.2008
[2011/38]
Former [2010/37]BE23.01.2008
CY23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
TR23.01.2008
SE23.04.2008
PT23.06.2008
IE31.07.2008
LU31.07.2008
MC31.07.2008
Former [2010/32]BE23.01.2008
CY23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
SE23.04.2008
PT23.06.2008
IE31.07.2008
LU31.07.2008
MC31.07.2008
Former [2009/34]BE23.01.2008
CY23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
SE23.04.2008
PT23.06.2008
IE31.07.2008
MC31.07.2008
Former [2009/33]BE23.01.2008
CY23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
SE23.04.2008
PT23.06.2008
MC31.07.2008
Former [2009/18]BE23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
SE23.04.2008
PT23.06.2008
MC31.07.2008
Former [2008/48]BE23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
SE23.04.2008
PT23.06.2008
Former [2008/46]BE23.01.2008
DK23.01.2008
FI23.01.2008
SE23.04.2008
PT23.06.2008
Former [2008/43]BE23.01.2008
FI23.01.2008
PT23.06.2008
Former [2008/42]FI23.01.2008
PT23.06.2008
Former [2008/39]FI23.01.2008
Cited inInternational search[AD]WO9003370  (MICROPROBE CORP [US]) [AD] 1,3-92 * the whole document *;
 [A]WO9951775  (EPOCH PHARMACEUTICALS INC [US]) [A] 1,3-92 * the whole document *;
 [A]DE19823454  (EPIGENOMICS GMBH [DE]) [A] 15* abstract *;
 [XD]  - F. SEELA ET AL., "8-Aza-7-deazapurine DNA: Synthesis and duplex stability of oligonucleotides containing 7-substituted bases", NUCLEOSIDES & NUCLEOTIDES, (1999), vol. 18, pages 1399 - 1400, XP002157790 [XD] 1,3-11,14,20,23,24,26-29,31,34-48 * the whole document *
 [AD]  - OERTEL, FRANK ET AL, "Synthesis and properties of methylthiopyrazolo[3,4-d]pyrimidine 2'-deoxy-.beta.-D-ribonucleosides", LIEBIGS ANN. CHEM. (1992), (11), 1165-70, XP002157791 [AD] 1 * page 1165, structure 3b *
 [AD]  - GARAEVA, L. D. ET AL, "Studies on glycosides of 3,4,6-trisubstituted pyrazolo[3,4-d]pyrimidines. Synthesis of 2'-deoxyribonucleosides", NUCLEOSIDES NUCLEOTIDES (1991), 10(6), 1295-303, XP000980295 [AD] 1 * page 1297, structure 8 *
 [A]  - PETRIE C R ET AL, "A NOVEL BIOTINYLATED ADENYLATE ANALOGUE DERIVED FROM PYRAZOLOU3,4-DPYRIMIDINE FOR LABELING DNA PROBES", BIOCONJUGATE CHEMISTRY,US,AMERICAN CHEMICAL SOCIETY, WASHINGTON, (19911101), vol. 2, no. 6, ISSN 1043-1802, pages 441 - 446, XP000572789 [A] 1 * abstract page 442, structure 9 *

DOI:   http://dx.doi.org/10.1021/bc00012a011
 [AD]  - F. SEELA ET AL., "Duplex stability of oligonucleotides containing 7-substituted 7-deaza- and 8-aza-7-deazapurine nucleosides", NUCLEOSIDES & NUCLEOTIDES, (1997), vol. 16, pages 963 - 966, XP002157792 [AD] 1 * abstract page 963-964, structure 1-11 *
 [AD]  - G. BALOW ET AL., "Biophysical and antisense properties of oligodeoxynucleotides containing 7-propenyl-, 7-iodo- and 7-cyano-7-deaza-2-amino-2'-deoxyadenosines", NUCLEIC ACIDS RESEARCH, (1998), vol. 26, no. 14, pages 3350 - 3357, XP002157793 [AD] 1 * page 3351-3353, structures 1-21 *

DOI:   http://dx.doi.org/10.1093/nar/26.14.3350
 [AD]  - N. RAMZAEVA ET AL., "7-Deaza-2'-deoxyguanosines functionalized with 7-(omega-aminoalk-1-ynyl) residues", NUCLEOSIDES & NUCLEOTIDES, (1999), vol. 18, pages 1439 - 1440, XP002157794 [AD] 1,23 * the whole document *
ExaminationWO0164958
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