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Extract from the Register of European Patents

EP About this file: EP1458411

EP1458411 - ANTI-RANK LIGAND MONOCLONAL ANTIBODIES USEFUL IN TREATMENT OF RANK LIGAND MEDIATED DISORDERS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  28.07.2006
Database last updated on 15.11.2024
Most recent event   Tooltip28.07.2006Application deemed to be withdrawnpublished on 30.08.2006  [2006/35]
Applicant(s)For all designated states
SMITHKLINE BEECHAM CORPORATION
One Franklin Plaza P.O. Box 7929 Philadelphia
Pennsylvania 19103 / US
For all designated states
SMITHKLINE BEECHAM PLC
New Horizons Court Brentford
Middlesex TW8 9EP / GB
[N/P]
Former [2004/39]For all designated states
SMITHKLINE BEECHAM CORPORATION
One Franklin Plaza P.O. Box 7929
Philadelphia Pennsylvania 19103 / US
For all designated states
SMITHKLINE BEECHAM PLC
New Horizons Court
Brentford, Middlesex TW8 9EP / GB
Inventor(s)01 / SWEET, Raymond, W.
108 Edgehill Road
Bala-Cynwyd, PA 19004 / US
02 / TORNETTA, Mark, A.
200 Great Valley Parkway
Malvern, PA 19355 / US
03 / TRUNEH, Alemseged
709 Swedeland Road
King of Prussia, PA / US
04 / WATTAM, Trevor A.
New Frontiers Science Park South, Third Avenue
Harlow, Essex CM19 5AW / GB
 [2004/39]
Representative(s)Giddings, Peter John, et al
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[N/P]
Former [2004/39]Giddings, Peter John, Dr., et al
GlaxoSmithKline Corporate Intellectual Property (CN9.25.1) 980 Great West Road
Brentford, Middlesex TW8 9GS / GB
Application number, filing date01968064.421.08.2001
[2004/39]
WO2001US26161
Priority number, dateUS20000226524P21.08.2000         Original published format: US 226524 P
US20000230639P07.09.2000         Original published format: US 230639 P
[2004/39]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0215846
Date:28.02.2002
Language:EN
[2002/09]
Type: A2 Application without search report 
No.:EP1458411
Date:22.09.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 28.02.2002 takes the place of the publication of the European patent application.
[2004/39]
Search report(s)International search report - published on:US01.07.2004
(Supplementary) European search report - dispatched on:EP12.07.2004
ClassificationIPC:A61K39/395, C07K16/28, C12N5/18
[2004/39]
CPC:
C07K16/2875 (EP,US); A61P1/04 (EP); A61P17/06 (EP);
A61P19/02 (EP); A61P19/08 (EP); A61P19/10 (EP);
A61P25/28 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P43/00 (EP); A61K2039/505 (EP,US); C07K2317/56 (EP,US);
C07K2317/565 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/39]
TitleGerman:ANTI-RANK LIGANDEN MONOKLONALE ANTIKÖRPER NÜTZLICH ZUR BEHANDLUNG VON RANK LIGANDEN VERMITTELTEN STÖRUNGEN[2004/39]
English:ANTI-RANK LIGAND MONOCLONAL ANTIBODIES USEFUL IN TREATMENT OF RANK LIGAND MEDIATED DISORDERS[2004/39]
French:ANTICORPS MONOCLONAUX LIGANDS ANTI-RANK CONVENANT AU TRAITEMENT DE TROUBLES LIES AUX LIGANDS DE RANK[2004/39]
Entry into regional phase21.02.2003National basic fee paid 
21.02.2003Search fee paid 
21.02.2003Designation fee(s) paid 
21.02.2003Examination fee paid 
Examination procedure05.02.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
21.02.2003Examination requested  [2004/39]
01.03.2006Application deemed to be withdrawn, date of legal effect  [2006/35]
06.04.2006Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2006/35]
22.05.2006Despatch of a communication from the examining division (Time limit: M04)
Fees paidRenewal fee
06.08.2003Renewal fee patent year 03
06.08.2004Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.08.200505   M06   Not yet paid
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Documents cited:Search[X]WO9525167  (MERCK PATENT GMBH [DE], et al) [X] 5,7,9,10 * page 65; claim 4 *;
 [X]EP0921395  (PFIZER PROD INC [US]) [X] 5,7,9,10* page 45; claim 10 *;
 [X]WO9929865  (UNIV ROCKEFELLER [US]) [X] 1,13 * abstract * * page 5, lines 3-11 * * page 9, lines 6-27 * * page 11, line 15 - page 12, line 15 * * page 32, line 3 - page 33, line 7 * * page 51, line 19 - page 54, line 17 *;
 [X]WO0015807  (M & E BIOTECH A S [DK], et al) [X] 1,13 * abstract * * page 1, lines 3-18 * * page 7, lines 9-25 * * page 9, lines 11-15 * * page 40, line 25 - page 41, line 7 *;
 [X]  - MENAA C ET AL, "Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone.", THE JOURNAL OF CLINICAL INVESTIGATION. JUN 2000, (200006), vol. 105, no. 12, ISSN 0021-9738, pages 1833 - 1838, XP002278692 [X] 1,13 * abstract * * page 1834, column 2, paragraph 3 *

DOI:   http://dx.doi.org/10.1172/JCI9133
 [X]  - TSUKII KATSUYOSHI ET AL, "Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, &, (19980519), vol. 246, no. 2, ISSN 0006-291X, pages 337 - 341, XP002278693 [X] 1,13 * abstract * * page 338, column 1, paragraph 4 *

DOI:   http://dx.doi.org/10.1006/bbrc.1998.8610
 [X]  - NAGAI MASAZUMI ET AL, "Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, &, (20000316), vol. 269, no. 2, ISSN 0006-291X, pages 532 - 536, XP002278694 [X] 1,13 * abstract * * page 535, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1006/bbrc.2000.2314
International search[X]US5530101  (QUEEN CARY L [US], et al);
 [X]US5840299  (BENDIG MARY M [GB], et al);
 [Y]US6017729  (ANDERSON DIRK M [US]);
 [Y]  - YASUDA ET AL., "Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL", PROC. NATL. ACAD. SCI. USA, (199803), vol. 95, pages 3597 - 3602, XP002906679

DOI:   http://dx.doi.org/10.1073/pnas.95.7.3597
 [Y]  - KWON ET AL., "Functions of newly identified members of the tumor necrosis factor receptor/ligand superfamilies in lymphocytes", CURRENT OPINION IN IMMUNOLOGY, (1999), vol. 11, pages 340 - 345, XP004257544

DOI:   http://dx.doi.org/10.1016/S0952-7915(99)80054-5
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.