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Extract from the Register of European Patents

EP About this file: EP1319016

EP1319016 - MODIFIED FACTOR VIII [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 07.12.2007 Database last updated on 03.08.2024
Most recent event Tooltip	07.12.2007	Application deemed to be withdrawn	published on 09.01.2008 [2008/02]
Applicant(s)	For all designated states Emory University 1784 North Decatur Road, North Decatur Building, Suite 130 Atlanta, Georgia 30322 / US
	[N/P]
Former [2003/25]	For all designated states Emory University 1784 North Decatur Road, North Decatur Building, Suite 130 Atlanta, Georgia 30322 / US
Inventor(s)	01 / LOLLAR, John, S. 2568 Oak Crossing Drive Decatur, GA 80033 / US
	[2003/25]
Representative(s)	Fisher, Adrian John, et al Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB
	[N/P]
Former [2003/25]	Fisher, Adrian John, et al CARPMAELS & RANSFORD 43 Bloomsbury Square London WC1A 2RA / GB
Application number, filing date	01973263.5	19.09.2001
	[2003/25]
	WO2001US29431
Priority number, date	US20000234047P	19.09.2000 Original published format: US 234047 P
	US20000236460P	29.09.2000 Original published format: US 236460 P
	[2003/25]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO0224723
	Date:	28.03.2002
	Language:	EN
	[2002/12]
	Type:	A1 Application with search report
	No.:	EP1319016
	Date:	18.06.2003
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 28.03.2002 takes the place of the publication of the European patent application.
	[2003/25]
Search report(s)	International search report - published on:	US	28.03.2002
	(Supplementary) European search report - dispatched on:	EP	29.03.2006
Classification	IPC:	C07K14/00, C07K17/00, A61K38/00	[2003/25]
	CPC:	C07K14/755 (EP,US); C07K14/47 (KR); A61K38/37 (EP,US); A61P7/00 (EP); Y10S930/10 (EP,US)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2003/25]
Extension states	AL	28.02.2003
	LT	28.02.2003
	LV	28.02.2003
	MK	28.02.2003
	RO	28.02.2003
	SI	28.02.2003
Title	German:	MODIFIZIERTER FAKTOR VIII	[2003/25]
	English:	MODIFIED FACTOR VIII	[2003/25]
	French:	FACTEUR VIII MODIFIE	[2003/25]
Entry into regional phase	28.02.2003	National basic fee paid
	28.02.2003	Search fee paid
	28.02.2003	Designation fee(s) paid
	28.02.2003	Examination fee paid
Examination procedure	08.04.2002	Request for preliminary examination filed International Preliminary Examining Authority: US
	28.02.2003	Examination requested [2003/25]
	22.05.2006	Amendment by applicant (claims and/or description)
	28.12.2006	Despatch of a communication from the examining division (Time limit: M06)
	10.07.2007	Application deemed to be withdrawn, date of legal effect [2008/02]
	14.08.2007	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2008/02]
Fees paid	Renewal fee
	28.02.2003	Renewal fee patent year 03
	23.09.2004	Renewal fee patent year 04
	21.09.2005	Renewal fee patent year 05
	27.09.2006	Renewal fee patent year 06
	Penalty fee
	Additional fee for renewal fee
	30.09.2007	07 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[XDY]US5888974 (LOLLAR JOHN S [US], et al) [XD] 24-29 * column 2, line 54 - column 4, line 19; claim - * [Y] 1-23,30-49;
		[X]WO9946274 (UNIV EMORY [US]) [X] 1-49 * page 41, lines 1-13; example -; claim -; table 4 * * page 4, line 26 - page 7, line 33 *;
		[PY]WO0112836 (HUTCHINSON FRED CANCER RES [US], et al) [PY] 1-49 * page 7, line 16 - line 30; figure 4; claim - *;
		[E]WO0170968 (OCTAGENE GMBH [DE], et al) [E] 1,9-11,16,20-30,33,36,40,43,46 * example -; claim - *;
		[DY] - BARROW R T ET AL, "Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/oorcine factor VIII molecules", BLOOD, W.B.SAUNDERS COMPANY, ORLANDO, FL, US, (20000115), vol. 95, no. 2, ISSN 0006-4971, pages 564 - 568, XP002963601 [DY] 1-49 * abstract *
		[DY] - HEALEY J F ET AL, "RESIDUES GLU2181-VAL2243 CONTAIN A MAJOR DETERMINANT OF THE INHIBITORY EPITOPE IN THE C2 DOMAIN OF HUMAN FACTOR VIII", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, (19981115), vol. 92, no. 10, ISSN 0006-4971, pages 3701 - 3709, XP000973753 [DY] 1-49 * abstract *
		[X] - LIU M-L ET AL, "Hemophilic factor VIIIC1- and C2-domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure", BLOOD, W.B.SAUNDERS COMPANY, ORLANDO, FL, US, (20000801), vol. 96, no. 3, ISSN 0006-4971, pages 979 - 987, XP002963100 [X] 1,9-11,20-30,33,36,40,43,46 * abstract *
	International search	[Y] - LIN S.W. ET AL., "Characterization of genetic defects of hemophilia A in patients of Chinese origin", GENOMICS, (199312), vol. 18, no. 3, pages 496 - 504, XP002906122 DOI: http://dx.doi.org/10.1016/S0888-7543(05)80367-2
		[A] - GILBERT G. ET AL., "Four hydrophobic amino acids of the factor VIII C2 domain contribute to the membrane-binding motif", BLOOD, (200011), vol. 96, no. 11, PART 1, page 633A, XP002906123

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