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Extract from the Register of European Patents

EP About this file: EP1339399

EP1339399 - COMBINATIONS OF DRUGS (E.G., CHLORPROMAZINE AND PENTAMIDINE) FOR THE TREATMENT OF NEOPLASTIC DISORDERS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.01.2007
Database last updated on 20.07.2024
Most recent event   Tooltip09.11.2007Change - lapse in a contracting state
State(s) deleted from list of lapses: IT
published on 12.12.2007  [2007/50]
Applicant(s)For all designated states
CombinatoRx, Incorporated
650 Albany Street
Boston, MA 02118 / US
[2006/09]
Former [2003/36]For all designated states
Combinatorx, Incorporated
650 Albany Street
Boston, MA 02118 / US
Inventor(s)01 / BORISY, Alexis
31 Revere Street, Apartment 2
Boston, MA 02114 / US
02 / KEITH, Curtis
42 Rutland Square, Apartment 2
Boston, MA 02118 / US
03 / FOLEY, Michael, A.
93 Wolcott Road
Chestnut Hill, MA 02467 / US
04 / STOCKWELL, Brent, R.
59 West Cedar Street, Apartment 4
Boston, MA 02114 / US
 [2003/36]
Representative(s)Gervasi, Gemma
Notarbartolo & Gervasi GmbH
Bavariaring 21
80336 München / DE
[N/P]
Former [2003/36]Gervasi, Gemma, Dr.
Notarbartolo & Gervasi GmbH, Bavariaring 21
80336 München / DE
Application number, filing date01994213.530.10.2001
[2003/36]
WO2001US47959
Priority number, dateUS2000070692906.11.2000         Original published format: US 706929
[2003/36]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO02058684
Date:01.08.2002
Language:EN
[2002/31]
Type: A2 Application without search report 
No.:EP1339399
Date:03.09.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 01.08.2002 takes the place of the publication of the European patent application.
[2003/36]
Type: B1 Patent specification 
No.:EP1339399
Date:01.03.2006
Language:EN
[2006/09]
Search report(s)International search report - published on:EP17.04.2003
ClassificationIPC:A61K31/155, A61P35/00
[2005/29]
CPC:
A61K45/06 (EP,US); A61K31/5415 (EP,KR,US); A61K31/155 (EP,US);
A61K31/495 (EP,US); A61K31/54 (EP,US); A61P35/00 (EP);
A61P43/00 (EP) (-)
C-Set:
A61K31/155, A61K2300/00 (US,EP);
A61K31/495, A61K2300/00 (US,EP);
A61K31/5415, A61K2300/00 (EP,US);
A61K31/54, A61K2300/00 (US,EP);
A61K31/54, A61K31/135 (EP,US)
(-)
Former IPC [2003/36]A61K31/155
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/36]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:ARZNEIMITTELKOMBINATIONEN (Z.B. CHLORPROMAZIN UND PENTAMIDIN) ZUR THERAPIE VON NEOPLASTISCHEN ERKRANKUNGEN[2003/36]
English:COMBINATIONS OF DRUGS (E.G., CHLORPROMAZINE AND PENTAMIDINE) FOR THE TREATMENT OF NEOPLASTIC DISORDERS[2003/36]
French:COMBINAISONS DE MEDICAMENTS (PAR EXEMPLE DE CHLORPROMAZINE ET DE PENTAMIDINE) POUR LE TRAITEMENT DE TROUBLES NEOPLASIQUES[2003/36]
Entry into regional phase05.06.2003National basic fee paid 
05.06.2003Designation fee(s) paid 
05.06.2003Examination fee paid 
Examination procedure30.05.2002Request for preliminary examination filed
International Preliminary Examining Authority: EP
05.06.2003Amendment by applicant (claims and/or description)
05.06.2003Examination requested  [2003/36]
03.02.2004Despatch of a communication from the examining division (Time limit: M06)
02.08.2004Reply to a communication from the examining division
12.08.2004Despatch of a communication from the examining division (Time limit: M04)
23.09.2004Reply to a communication from the examining division
18.01.2005Despatch of a communication from the examining division (Time limit: M04)
27.05.2005Reply to a communication from the examining division
02.08.2005Communication of intention to grant the patent
01.12.2005Fee for grant paid
01.12.2005Fee for publishing/printing paid
Opposition(s)04.12.2006No opposition filed within time limit [2007/06]
Fees paidRenewal fee
23.10.2003Renewal fee patent year 03
25.10.2004Renewal fee patent year 04
27.10.2005Renewal fee patent year 05
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Lapses during opposition  Tooltipdeleted
[2007/50]
Former [2007/37]IT01.03.2006
Cited inInternational search[XY]CH681780  (PATRINOVE, et al) [X] 10 * claims 1,4,6 * [Y] 1-9,11-20;
 [XY]  - HAIT W N ET AL, "Phase I trial of combined therapy with bleomycin and the calmodulin antagonist, trifluoperazine.", CANCER CHEMOTHERAPY AND PHARMACOLOGY, (1989) 23 (6) 358-62. JOURNAL CODE: 7806519. ISSN: 0344-5704., Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510., XP001095611 [X] 10 * abstract * [Y] 1-9,11-20

DOI:   http://dx.doi.org/10.1007/BF00435836
 [XY]  - DANIEL D. VON HOFF, "Use of Daunorubicin in Patients With Solid Tumors", SEMINARS IN ONCOLOGY, (1984), vol. 11, no. 4, pages 23 - 27, XP001098570 [X] 10 * page 25, column L * [Y] 1-9,11-20
 [Y]  - D.R. MAKULU ET AL, "Effects of Pentamidine Upon Murine Leukemia and the Walker 256 Carcinoma (W256)", THE PHARMACOLOGIST, (1974), vol. 16, no. 2, page abs. no. 105, XP001095144 [Y] 1-9,11-20 * abstract *
 [Y]  - SHIN-ICHI AKIYAMA ET AL, "Circumvention of Multiple-Drug Resistance in Human Cancer Cells by Thioridazine, Trifluoperazine, and Chlorpromazine", JOURNAL OF THE NATIONAL CANCER INSTITUTE, (1986), vol. 76, no. 5, pages 839 - 844, XP001098572 [Y] 1-9,11-20 * abstract *
 [Y]  - RADERER M. ET AL, "Clinical trials of agents that reverse multidrug resistance: A literature review.", CANCER, (1993) 72/12 (3553-3563)., XP001095140 [Y] 1-9,11-20 * page 3559 *
Examination   - VALERIOTE F.; LIN H.-S., "SYNERGISTIC INTERACTION OF ANTICANCER AGENTS: A CELLULAR PERSPECTIVE", CANCER CHEMOTHERAPY REPORTS, (197509), vol. 59, no. 5, pages 895 - 900, XP009019750
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.