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Extract from the Register of European Patents

EP About this file: EP1343916

EP1343916 - NUCLEIC ACID AMPLIFICATION METHODS [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  06.05.2011
Database last updated on 22.01.2025
Most recent event   Tooltip06.05.2011Refusal of applicationpublished on 08.06.2011  [2011/23]
Applicant(s)For all designated states
Hamilton Thorne Biosciences, Inc
100 Cummings Center, Suite 465E
Beverly, MA 01915 / US
[2007/01]
Former [2003/38]For all designated states
Zhang, David Y.
82-84 165th Street
Jamaica, NY 11432 / US
For all designated states
Brandwein, Margaret
180-20 Hovenden Road
Jamaica Estates, NY 11432 / US
For all designated states
Hsuih, Terence
4-74 48th Avenue 10B
Long Island City, NY 11109 / US
Inventor(s)01 / see applicant
...
 [2003/38]
Representative(s)Raggers, René John, et al
Exter Polak & Charlouis B.V. P.O. Box 3241
2280 GE Rijswijk / NL
[2010/46]
Former [2003/38]Wittop Koning, Tom Hugo, et al
Exter Polak & Charlouis B.V., P.O. Box 3241
2280 GE Rijswijk / NL
Application number, filing date01998621.503.12.2001
[2003/38]
WO2001US45822
Priority number, dateUS2000072826501.12.2000         Original published format: US 728265
[2003/38]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0244339
Date:06.06.2002
Language:EN
[2002/23]
Type: A2 Application without search report 
No.:EP1343916
Date:17.09.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 06.06.2002 takes the place of the publication of the European patent application.
[2003/38]
Search report(s)International search report - published on:US30.05.2003
(Supplementary) European search report - dispatched on:EP28.12.2004
ClassificationIPC:C12Q1/68, C12P19/34
[2003/38]
CPC:
C12Q1/682 (EP,US); C12P19/34 (US); C12Q1/6834 (EP,US);
C12Q1/6862 (EP,US); Y10T436/143333 (US)
C-Set:
C12Q1/682, C12Q2537/137, C12Q2533/107, C12Q2531/125 (EP,US);
C12Q1/6834, C12Q2563/143, C12Q2537/137, C12Q2533/107 (US,EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/38]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:NUKLEINSÄUREAMPLIFIKATIONSVERFAHREN[2003/38]
English:NUCLEIC ACID AMPLIFICATION METHODS[2003/38]
French:PROCEDE D'AMPLIFICATION DE L'ACIDE NUCLEIQUE[2003/38]
Entry into regional phase13.06.2003National basic fee paid 
13.06.2003Search fee paid 
13.06.2003Designation fee(s) paid 
13.06.2003Examination fee paid 
Examination procedure01.07.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
13.06.2003Examination requested  [2003/38]
22.07.2003Amendment by applicant (claims and/or description)
17.03.2005Despatch of a communication from the examining division (Time limit: M06)
27.09.2005Reply to a communication from the examining division
20.01.2006Despatch of a communication from the examining division (Time limit: M04)
19.05.2006Reply to a communication from the examining division
03.04.2008Despatch of a communication from the examining division (Time limit: M06)
13.10.2008Reply to a communication from the examining division
05.06.2009Despatch of a communication from the examining division (Time limit: M06)
19.01.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
24.03.2010Reply to a communication from the examining division
17.01.2011Cancellation of oral proceeding that was planned for 20.01.2011
20.01.2011Despatch of communication that the application is refused, reason: substantive examination [2011/23]
20.01.2011Date of oral proceedings (cancelled)
30.01.2011Application refused, date of legal effect [2011/23]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  17.03.2005
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
24.03.2010Request for further processing filed
24.03.2010Full payment received (date of receipt of payment)
Request granted
01.04.2010Decision despatched
Fees paidRenewal fee
23.12.2003Renewal fee patent year 03
07.01.2005Renewal fee patent year 04
30.12.2005Renewal fee patent year 05
28.12.2006Renewal fee patent year 06
20.12.2007Renewal fee patent year 07
29.12.2008Renewal fee patent year 08
30.12.2009Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
31.12.200404   M06   Fee paid on   28.01.2005
31.12.201010   M06   Not yet paid
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Documents cited:Search[X]WO9804746  (SINAI SCHOOL MEDICINE [US]) [X] 1-28 * figures 1-19; examples 1-11; claims 1-22 *;
 [X]WO9804745  (SINAI SCHOOL MEDICINE [US]) [X] 1-28 * figures 1-19; examples 1-11; claims 1-20 *;
 [DX]US5942391  (ZHANG DAVID Y [US], et al) [DX] 1-28 * column 17; examples 1-11; claims 1-21 * * column 21, line 55 - line 63 * * column 23, line 38 * * column 25; figures 1-19 *;
 [X]  - ZHANG D Y ET AL, "Amplification of target-specific, ligation-dependent circular probe", GENE 12 MAY 1998 NETHERLANDS, (19980512), vol. 211, no. 2, ISSN 0378-1119, pages 277 - 285, XP004120590 [X] 1-14,22,23 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0378-1119(98)00113-9
 [X]  - THOMAS D C ET AL, "AMPLIFICATION OF PADLOCK PROBES FOR DNA DIAGNOSTICS BY CASCADE ROLLING CIRCLE AMPLIFICATION OR THE POLYMERASE CHAIN REACTION", ARCHIVES OF PATHOLOGY, AMERICAN MEDICAL ASSOCIATION, CHICAGO, IL,, US, (199912), vol. 123, no. 12, ISSN 0003-9985, pages 1170 - 1176, XP008001739 [X] 1-14,22,23 * the whole document *
 [X]  - ZHANG D Y ET AL, "Detection of infectious agents by RAM amplification", ABSTRACTS OF THE GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, & 99TH GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY; CHICAGO, ILLINOIS, USA; MAY 30-JUNE 3, 1999, (1999), vol. 99, ISSN 1060-2011, pages 203 - 204, XP009040693 [X] 1-14,22,23 * abstract * * page 1174, column R - page 1176 *
 [X]  - WU F ET AL, "Detection of cytomegalovirus (CMV) immediate early mRNA in infected cells by novel ligation-dependent PCR assay", ABSTRACTS OF THE GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, & 97TH GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY; MIAMI BEACH, FLORIDA, USA; MAY 4-8, 1997, (1997), vol. 97, no. 0, ISSN 1060-2011, page 155, XP009040694 [X] 15-21 * abstract *
 [X]  - PUNWANEY R ET AL, "Human papillomavirus may be common within nasopharyngeal carcinoma of Caucasian Americans: Investigation of Epstein-Barr virus and human papillomavirus in eastern and western nasopharyngeal carcinoma using ligation-dependent polymerase chain reaction", HEAD AND NECK 1999 UNITED STATES, (1999), vol. 21, no. 1, ISSN 1043-3074, pages 21 - 29, XP009040696 [X] 15-21 * abstract *

DOI:   http://dx.doi.org/10.1002/(SICI)1097-0347(199901)21:1<21::AID-HED3>3.0.CO;2-Z
International search[Y]US5854033  (LIZARDI PAUL M [MX]);
 [X]US5942391  (ZHANG DAVID Y [US], et al)
Examination   - ZHANG D Y ET AL, "THE RAM ASSAY: AN ISOTHERMAL GENE AMPLIFICATION METHOD", LABORATORY INVESTIGATION, NATURE PUBLISHING GROUP, US, (19980101), vol. 78, no. 1, ISSN 0023-6837, page 189A,ABSTR.NO.1109, XP009040692
    - UNRAU P ET AL, "NON-CLONING AMPLIFICATION OF SPECIFIC DNA FRAGMENTS FROM WHOLE GENOMIC DNA DIGESTS USING DNA INDEXERS", GENE, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/0378-1119(94)90001-9, (19940805), vol. 145, no. 2, ISSN 0378-1119, pages 163 - 169, XP002008283

DOI:   http://dx.doi.org/10.1016/0378-1119(94)90001-9
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.