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Extract from the Register of European Patents

EP About this file: EP1258530

EP1258530 - Gaba-A receptor subunits (alpha-2, alpha-3, alpha-5, alpha -6, beta-2) and transfected cells expressing them [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.08.2004
Database last updated on 20.09.2024
Most recent event   Tooltip05.06.2009Change - representativepublished on 08.07.2009  [2009/28]
Applicant(s)For all designated states
MERCK SHARP & DOHME LTD.
Hertford Road
Hoddesdon, Hertfordshire EN11 9NU / GB
[N/P]
Former [2002/47]For all designated states
MERCK SHARP & DOHME LTD.
Hertford Road
Hoddesdon Hertfordshire EN11 9NU / GB
Inventor(s)01 / Handingham, Karen Louise
Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR / GB
02 / Le Bourdelles, Beatrice
Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR / GB
03 / Whiting, Paul John
Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR / GB
04 / Wingrove, Peter Baxter
Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR / GB
 [2002/47]
Representative(s)Horgan, James Michael Frederic
Merck & Co., Inc.
European Patent Department
Terlings Park
Eastwick Road, Harlow
Essex CM20 2QR / GB
[N/P]
Former [2009/28]Horgan, James Michael Frederic
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow
Essex CM20 2QR / GB
Former [2002/47]Horgan, James Michael Frederic
Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR / GB
Application number, filing date02078136.509.06.1992
[2002/47]
Priority number, dateGB1991001250411.06.1991         Original published format: GB 9112504
[2002/47]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1258530
Date:20.11.2002
Language:EN
[2002/47]
Type: A3 Search report 
No.:EP1258530
Date:27.11.2002
[2002/48]
Search report(s)(Supplementary) European search report - dispatched on:EP16.10.2002
ClassificationIPC:C12N15/12, C12N5/10, C07K14/705, G01N33/566
[2002/47]
CPC:
C07K14/70571 (EP); A61K38/00 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [2002/47]
TitleGerman:Gaba-a Rezeptoruntereinheiten (alpha-2, alpha-3, alpha-5, alpha-6, beta-2) und transfektierte Zellen, die diese expremieren[2002/47]
English:Gaba-A receptor subunits (alpha-2, alpha-3, alpha-5, alpha -6, beta-2) and transfected cells expressing them[2002/47]
French:Sous-unités (alpha-2, alpha-3, alpha-5, alpha-6, beta-2) de récepteur de gaba-a et cellules transfectées les exprimant[2002/47]
Examination procedure27.05.2003Examination requested  [2003/31]
18.09.2003Despatch of a communication from the examining division (Time limit: M06)
30.03.2004Application deemed to be withdrawn, date of legal effect  [2004/42]
10.05.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2004/42]
Parent application(s)   TooltipEP92911528.5  / EP0589930
Fees paidRenewal fee
02.12.2002Renewal fee patent year 03
02.12.2002Renewal fee patent year 04
02.12.2002Renewal fee patent year 05
02.12.2002Renewal fee patent year 06
02.12.2002Renewal fee patent year 07
02.12.2002Renewal fee patent year 08
02.12.2002Renewal fee patent year 09
02.12.2002Renewal fee patent year 10
02.12.2002Renewal fee patent year 11
30.06.2003Renewal fee patent year 12
Penalty fee
Additional fee for renewal fee
30.06.200413   M06   Not yet paid
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Documents cited:Search[X]  - YMER S ET AL, "GABAA RECEPTOR BETA SUBUNIT HETEROGENEITY: FUNCTIONAL EXPRESSION OF CLONED CDNAS", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, (1989), vol. 8, no. 6, ISSN 0261-4189, pages 1665 - 1670, XP000674574 [X] 9-11 * The whole document especially figure 2 the bovine and rat GABA A receptor beta 2 subunit sequences *
 [XY]  - SCHOFIELD P R ET AL, "SEQUENCE AND EXPRESSION OF HUMAN GABAA RECEPTOR ALPHA 1 AND BETA1 SUBUNITS", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (19890227), vol. 244, no. 2, ISSN 0014-5793, pages 361 - 364, XP000653686 [X] 10,11 * page 364 * [Y] 1-3

DOI:   http://dx.doi.org/10.1016/0014-5793(89)80563-0
 [Y]  - YMER S ET AL, "STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF THE GAMMA-1 SUBUNIT OF GABA-A BENZODIAZEPINE RECEPTORS", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, (1990), vol. 9, no. 10, ISSN 0261-4189, pages 3261 - 3267, XP002213588 [Y] 1-3 * the whole document *
 [X]  - SCHOFIELD P R ET AL, "SEQUENCE AND FUNCTIONAL EXPRESSION OF THE GABAA RECEPTOR SHOWS A LIGAND-GATED RECEPTOR SUPER-FAMILY", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, (19870716), vol. 328, ISSN 0028-0836, pages 221 - 227, XP000197555 [X] 10 * figure 1 *

DOI:   http://dx.doi.org/10.1038/328221a0
 [PX]  - HADINGHAM K L ET AL, "STABLE EXPRESSION OF MAMMALIAN TYPE A GAMMA AMINOBUTYRIC ACID RECEPTORS IN MOUSE CELLS DEMONSTRATION OF FUNCTIONAL ASSEMBLY OF BENZODIAZEPINE-RESPONSIVE SITES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, 1992, (1992), vol. 89, no. 14, ISSN 0027-8424, pages 6378 - 6382, XP002213589 [PX] 1-11,16 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.89.14.6378
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