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Extract from the Register of European Patents

EP About this file: EP1285578

EP1285578 - Transgenic animal model of Alzheimer's disease [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.09.2008
Database last updated on 20.09.2024
Most recent event   Tooltip13.08.2010Lapse of the patent in a contracting state
New state(s): TR
published on 15.09.2010  [2010/37]
Applicant(s)For all designated states
SMITHKLINE BEECHAM PLC
980 Great West Road Brentford
Middlesex TW8 9GS / GB
[2007/44]
Former [2003/09]For all designated states
SMITHKLINE BEECHAM PLC
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
Inventor(s)01 / Geppert, Martin, c/o GlaxoSmithKline
New Frontiers Science Park
Harlow, Essex CM19 5AW / GB
02 / Harper, Alexander James, c/o GlaxoSmithKline
New Frontiers Science Park
Harlow, Essex CM19 5AW / GB
03 / Harrison, Steve Mark, c/o GlaxoSmithKline
New Frontiers Science Park
Harlow, Essex CM19 5AW / GB
04 / Prosser, Hayon, c/o GlaxoSmithKline
New Frontiers Science Park
Harlow, Essex CM19 5AW / GB
 [2003/09]
Representative(s)Giddings, Peter John
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[N/P]
Former [2003/09]Giddings, Peter John, Dr.
GlaxoSmithKline Corporate Intellectual Property (CN9.25.1) 980 Great West Road
Brentford, Middlesex TW8 9GS / GB
Application number, filing date02078428.620.08.2002
[2003/09]
Priority number, dateGB2001002034221.08.2001         Original published format: GB 0120342
GB2001002672307.11.2001         Original published format: GB 0126723
[2003/09]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1285578
Date:26.02.2003
Language:EN
[2003/09]
Type: A3 Search report 
No.:EP1285578
Date:17.09.2003
[2003/38]
Type: B1 Patent specification 
No.:EP1285578
Date:31.10.2007
Language:EN
[2007/44]
Search report(s)(Supplementary) European search report - dispatched on:EP07.08.2003
ClassificationIPC:A01K67/027, C12N15/57, C12N15/85, C12N15/89, C12Q1/37, G01N33/50, C07K14/47
[2003/38]
CPC:
C12N15/8509 (EP,US); A01K67/0275 (EP,US); C07K14/4711 (EP,US);
C12N9/6478 (EP,US); A01K2217/05 (EP,US); A01K2227/105 (EP,US);
A01K2267/0312 (EP,US); C12N2830/008 (EP,US); C12N2830/85 (EP,US);
C12N2840/203 (EP,US) (-)
Former IPC [2003/09]A01K67/027, C12N15/57, C12N15/85, C12N15/89, C12Q1/37, G01N33/50
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2003/09]
TitleGerman:Transgenes Tiermodell für Alzheimer-Erkrankung[2003/09]
English:Transgenic animal model of Alzheimer's disease[2003/09]
French:Modèle animal transgénique pour la maladie d'Alzheimer[2003/09]
Examination procedure20.08.2002Examination requested  [2003/09]
08.08.2005Despatch of a communication from the examining division (Time limit: M06)
02.02.2006Reply to a communication from the examining division
28.02.2006Despatch of a communication from the examining division (Time limit: M06)
07.09.2006Reply to a communication from the examining division
07.03.2007Communication of intention to grant the patent
04.07.2007Fee for grant paid
04.07.2007Fee for publishing/printing paid
Opposition(s)01.08.2008No opposition filed within time limit [2008/41]
Fees paidRenewal fee
06.08.2004Renewal fee patent year 03
08.08.2005Renewal fee patent year 04
07.08.2006Renewal fee patent year 05
03.08.2007Renewal fee patent year 06
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Lapses during opposition  TooltipAT31.10.2007
CH31.10.2007
CY31.10.2007
CZ31.10.2007
DK31.10.2007
EE31.10.2007
FI31.10.2007
LI31.10.2007
NL31.10.2007
SK31.10.2007
TR31.10.2007
BG31.01.2008
SE31.01.2008
GR01.02.2008
PT31.03.2008
[2010/37]
Former [2009/33]AT31.10.2007
CH31.10.2007
CY31.10.2007
CZ31.10.2007
DK31.10.2007
EE31.10.2007
FI31.10.2007
LI31.10.2007
NL31.10.2007
SK31.10.2007
BG31.01.2008
SE31.01.2008
GR01.02.2008
PT31.03.2008
Former [2009/22]AT31.10.2007
CH31.10.2007
CZ31.10.2007
DK31.10.2007
EE31.10.2007
FI31.10.2007
LI31.10.2007
NL31.10.2007
SK31.10.2007
BG31.01.2008
SE31.01.2008
GR01.02.2008
PT31.03.2008
Former [2009/15]AT31.10.2007
CH31.10.2007
CZ31.10.2007
DK31.10.2007
FI31.10.2007
LI31.10.2007
NL31.10.2007
SK31.10.2007
BG31.01.2008
SE31.01.2008
GR01.02.2008
PT31.03.2008
Former [2009/13]AT31.10.2007
CH31.10.2007
CZ31.10.2007
DK31.10.2007
FI31.10.2007
LI31.10.2007
NL31.10.2007
SK31.10.2007
BG31.01.2008
SE31.01.2008
GR01.02.2008
PT31.03.2008
Former [2008/39]AT31.10.2007
CH31.10.2007
CZ31.10.2007
DK31.10.2007
LI31.10.2007
NL31.10.2007
SK31.10.2007
BG31.01.2008
SE31.01.2008
PT31.03.2008
Former [2008/35]AT31.10.2007
CH31.10.2007
CZ31.10.2007
DK31.10.2007
LI31.10.2007
NL31.10.2007
BG31.01.2008
SE31.01.2008
PT31.03.2008
Former [2008/29]AT31.10.2007
CH31.10.2007
LI31.10.2007
NL31.10.2007
BG31.01.2008
SE31.01.2008
PT31.03.2008
Former [2008/24]CH31.10.2007
LI31.10.2007
NL31.10.2007
BG31.01.2008
SE31.01.2008
PT31.03.2008
Former [2008/23]CH31.10.2007
LI31.10.2007
NL31.10.2007
SE31.01.2008
Documents cited:Search[Y]  - HARPER A J ET AL, "Mouse models for AD;characterisation of beta-secretase (Asp2) overexpressing mice using a novel gene expression strategy.", SOCIETY FOR NEUROSCIENCE ABSTRACTS, 31st Annual Meeting of the Society for Neuroscience;San Diego, California, USA; November 10-15, 2001, (2001), vol. 27, no. 1, ISSN 0190-5295, page 852, XP009013867 [Y] 1-13 * abstract *
 [Y]  - HERNANDEZ-SANCHEZ CATALINA ET AL, "Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, March 13, 2001, (20010313), vol. 98, no. 6, ISSN 0027-8424, pages 3549 - 3554, XP002247671 [Y] 1-13 * page 3553, column 2, paragraph 3 - page 3554, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1073/pnas.051012898
 [YD]  - TANG Y-P ET AL, "Genetic enhancement of learning and memory in mice", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, (19990902), vol. 401, no. 6748, ISSN 0028-0836, pages 63 - 69, XP002199188 [YD] 1-13 * page 62, column 1, paragraph 3 *

DOI:   http://dx.doi.org/10.1038/43432
 [A]  - SKOVRONSKY D M ET AL, "beta-Secretase revealed: starting gate for race to novel therapies for Alzheimer's disease", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, (200005), vol. 21, no. 5, ISSN 0165-6147, pages 161 - 163, XP004198178 [A] * page 162, column 2, paragraph 3 - column 3, paragraph 3 *

DOI:   http://dx.doi.org/10.1016/S0165-6147(00)01467-X
 [A]  - JANUS C ET AL, "TRANSGENIC MOUSE MODELS OF ALZHEIMER'S DISEASE", BIOCHIMICA ET BIOPHYSICA ACTA, AMSTERDAM, NL, (20000726), vol. 1502, no. 1, ISSN 0006-3002, pages 63 - 75, XP001018988
 [DA]  - HUSSAIN I ET AL, "IDENTIFICATION OF A NOVEL ASPARTIC PROTEASE (ASP 2) AS SS-SECRETASE", MOLECULAR AND CELLULAR NEUROSCIENCES, SAN DIEGO, US, (1999), vol. 14, no. 6, ISSN 1044-7431, pages 419 - 427, XP000908710 [DA] * the whole document *

DOI:   http://dx.doi.org/10.1006/mcne.1999.0811
ExaminationWO0047618
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