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Extract from the Register of European Patents

EP About this file: EP1388544

EP1388544 - Anti-idiotypic antibodies against factor VIII inhibitor and uses thereof [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  08.04.2005
Database last updated on 02.11.2024
Most recent event   Tooltip25.09.2009Change - representativepublished on 28.10.2009  [2009/44]
Applicant(s)For all designated states
D. Collen Research Foundation vzw
Onderwijs en Navorsing, Campus Gasthuisberg K.U. Leuven, Herestraat 49
3000 Leuven / BE
[N/P]
Former [2004/07]For all designated states
D. Collen Research Foundation vzw
Onderwijs en Navorsing, Campus Gasthuisberg K.U. Leuven, Herestraat 49
3000 Leuven / BE
Inventor(s)01 / Gille, Jean Guy G.
avenue de l'Exposition 410
1090 Bruxelles / BE
02 / Saint-Remy, Jean-Marie R.
Rue du Lambais 79
1390 Grez-Doiceau / BE
03 / Jacquemin, Marc G.
rue Morimont 45
5330 Sart-Bernard / BE
 [2004/07]
Representative(s)Bird, Ariane, et al
Bird Goën & Co
Wetenschapspark Arenberg
Gaston Geenslaan 9
3001 Heverlee / BE
[N/P]
Former [2009/44]Bird, Ariane, et al
Bird Goën & Co. Klein Dalenstraat 42A
3020 Winksele / BE
Former [2004/07]Hertoghe, Kris Angèle Louisa, et al
Bird Goen & Co, Klein Dalenstraat 42A
3020 Winksele / BE
Application number, filing date02447150.031.07.2002
[2004/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1388544
Date:11.02.2004
Language:EN
[2004/07]
Search report(s)(Supplementary) European search report - dispatched on:EP10.02.2003
ClassificationIPC:C07K16/42, C07K14/705, C12N5/16, A61K38/17, A61K38/08
[2004/07]
CPC:
C07K16/4241 (EP,US); A61P43/00 (EP); A61P7/04 (EP);
A61K2039/505 (EP,US)
Designated contracting states(deleted) [2004/45]
Former [2004/07]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE,  SK,  TR 
TitleGerman:Anti-Idiotypische Antikörper gegen Factor VIII-Inhibitor und Verwendungen davon[2004/07]
English:Anti-idiotypic antibodies against factor VIII inhibitor and uses thereof[2004/07]
French:Anticorps anti-idiotypes dirigés contre l'inhibiteur de facteur VIII et leurs applications[2004/07]
Biological materialThis application mentions deposited biological material, check the file for details
Examination procedure12.08.2004Application deemed to be withdrawn, date of legal effect  [2005/21]
16.12.2004Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2005/21]
Fees paidPenalty fee
Penalty fee Rule 85a EPC 1973
20.09.2004BE   M01   Not yet paid
20.09.2004DE   M01   Not yet paid
20.09.2004FR   M01   Not yet paid
20.09.2004GB   M01   Not yet paid
20.09.2004IT   M01   Not yet paid
20.09.2004NL   M01   Not yet paid
Penalty fee Rule 85b EPC 1973
20.09.2004M01   Not yet paid
Additional fee for renewal fee
31.07.200403   M06   Not yet paid
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Documents cited:Search[A]WO9958680  (SANQUIN BLOEDVOORZIENING [NL], et al) [A] 1 * page 1, line 29 - page 3, line 19 ** page 5, lines 14-36 *;
 [DY]  - JACQUEMIN M G ET AL, "MECHANISM AND KINETICS OF FACTOR VIII INACTIVATION: STUDY WITH AN IGG4 MONOCLONAL ANTIBODY DERIVED FROM A HEMOPHILIA A PATIENT WITH INHIBITOR", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, (1998), vol. 92, no. 2, ISSN 0006-4971, pages 496 - 506, XP000906844 [DY] 1-4,9,11,12 * abstract * * page 503, column R, paragraph 1 - page 504, column R, paragraph L *
 [Y]  - SAINT-REMY J-M R ET AL, "ANTI-IDIOTYPIC ANTIBODIES: FROM REGULATION TO THERAPY OF FACTOR VIII INHIBITORS", VOX SANGUINIS, S. KARGER AG, BASEL, CH, (1999), vol. 77, no. SUPPL 1, ISSN 0042-9007, pages 21 - 24, XP008012175 [Y] 1-4,9,11,12 * page 23, column L, paragraph 3 - column R, paragraph L *

DOI:   http://dx.doi.org/10.1159/000056709
 [DA]  - GILLES JEAN GUY G ET AL, "Antibodies to idiotypes of human monoclonal anti-factor VIII (FVIII) antibodies neutralise their inhibitory activity.", BLOOD, Forty-first Annual Meeting of the American Society of Hematology;New Orleans, Louisiana, USA; December 3-7, 1999, (19991115), vol. 94, no. 10 SUPPL. 1 PART 1, ISSN 0006-4971, page 460a, XP001109476 [DA] 1-4,9,11,12 * abstract *
 [DA]  - LUBAHN B C ET AL, "Characterization of a monoclonal anti-idiotype antibody to human anti-factor VIII antibodies.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. UNITED STATES NOV 1990, (199011), vol. 87, no. 21, ISSN 0027-8424, pages 8232 - 8236, XP002227743 [DA] 1,9,11,12 * abstract * * page 8234, column L, paragraph 1 - column R, lines 19-21 * * page 8235, column R, paragraph 3 - page 8236, column R, paragraph 2 *

DOI:   http://dx.doi.org/10.1073/pnas.87.21.8232
 [DA]  - GILLES JEAN GUY ET AL, "Neutralizing antiidiotypic antibodies to factor VIII inhibitors after desensitization in patients with hemophilia A.", JOURNAL OF CLINICAL INVESTIGATION, (1996), vol. 97, no. 6, ISSN 0021-9738, pages 1382 - 1388, XP002227744 [DA] 1 * page 1385, column R, paragraph 2 - column R, paragraph L; figure 5 *

DOI:   http://dx.doi.org/10.1172/JCI118558
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