blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP1352061

EP1352061 - METHOD FOR INHIBITING THE EXPRESSION OF A TARGET GENE [Right-click to bookmark this link]
StatusOpposition rejected
Status updated on  28.03.2014
Database last updated on 14.09.2024
Most recent event   Tooltip28.03.2014Opposition rejectedpublished on 30.04.2014  [2014/18]
Applicant(s)For all designated states
Alnylam Europe AG
Schleissheimer Str. 25
80333 München / DE
[2007/38]
Former [2005/21]For all designated states
Alnylam Europe AG
Fritz-Hornschuch-Strasse 9
95326 Kulmbach / DE
Former [2004/06]For all designated states
Ribopharma AG
Fritz-Hornschuch-Strasse 9
95326 Kulmbach / DE
Former [2003/42]For all designated states
Ribopharma AG
Universitätsstrasse 30
95447 Bayreuth / DE
Inventor(s)01 / KREUTZER, Roland
Glotzdorf 26
95466 Weidenberg / DE
02 / LIMMER, Stephan
Am Buttergraben 11
95326 Kulmbach / DE
03 / LIMMER, Sylvia
Am Buttergraben 11
95326 Kulmbach / DE
04 / HADWIGER, Philipp
Rotsteinweg 16a
95326 Kulmbach / DE
 [2007/28]
Former [2005/39]01 / KREUTZER, Roland
Glotzdorf 26
95466 Weidenberg / DE
02 / LIMMER, Stephan
Am Buttergraben 11
95326 Kulmbach / DE
03 / LIMMER, Sylvia
Am Buttergraben 11
95326 Kulmbach / DE
04 / HADWIGER, Philipp
Schlesierstr. 6
96264 Altenkunstadt / DE
Former [2003/50]01 / KREUTZER, Roland
Glotzdorf 26
95466 Weidenberg / DE
02 / LIMMER, Stephan
Am Buttergraben 11
95326 Kulmbach / DE
03 / LIMMER, Sylvia
Am Buttergraben 11
95326 Kulmbach / DE
04 / HADWIGER, Philipp
Almstr.5
95488 Bayreuth / DE
Former [2003/42]01 / KREUTZER, Roland
Universitätsstrasse 30
95447 Bayreuth / DE
02 / LIMMER, Stephan
Universitätsstrasse 30
95447 Bayreuth / DE
03 / ROST, Sylvia
Universitätsstrasse 30
95447 Bayreuth / DE
04 / HADWIGER, Philipp
Universitätsstrasse 30
95447 Bayreuth / DE
Representative(s)Wachenfeld, Joachim, et al
Vossius & Partner
Postfach 86 07 67
81634 München / DE
[N/P]
Former [2008/36]Wachenfeld, Joachim, et al
Vossius & Partner Postfach 86 07 67
81634 München / DE
Former [2007/38]Wachenfeld, Joachim, et al
Vossius & Partner Postfach 86 07 67
D-81634 München / DE
Former [2004/06]Gassner, Wolfgang, Dr., et al
Patentanwalt, Nägelsbachstrasse 49a
91052 Erlangen / DE
Former [2003/42]Gassner, Wolfgang, Dr.
Patentanwalt, Nägelsbachstrasse 49a
91052 Erlangen / DE
Application number, filing date02710786.109.01.2002
[2003/42]
WO2002EP00152
Priority number, dateDE200110058609.01.2001         Original published format: DE 10100586
DE200115528026.10.2001         Original published format: DE 10155280
DE200115841129.11.2001         Original published format: DE 10158411
DE200116015107.12.2001         Original published format: DE 10160151
[2003/42]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report
No.:WO02055693
Date:18.07.2002
Language:DE
[2002/29]
Type: A2 Application without search report 
No.:EP1352061
Date:15.10.2003
Language:DE
The application published by WIPO in one of the EPO official languages on 18.07.2002 takes the place of the publication of the European patent application.
[2003/42]
Type: B1 Patent specification 
No.:EP1352061
Date:31.05.2006
Language:DE
[2006/22]
Type: B9 Corrected patent specification 
No.:EP1352061
Date:07.03.2007
[2007/10]
Search report(s)International search report - published on:EP17.07.2003
ClassificationIPC:C12N15/11
[2003/42]
CPC:
C12N15/1138 (EP,US); A61P25/28 (EP); A61P31/12 (EP);
A61P33/06 (EP); A61P35/00 (EP); A61P35/04 (EP);
A61P37/02 (EP); A61P43/00 (EP); A61P5/00 (EP);
A61P9/00 (EP); C12N15/111 (EP,US); C12N15/1131 (EP,US);
A61K38/00 (EP,US); C12N2310/14 (EP,US); C12N2310/53 (EP,US);
C12N2320/50 (EP,US); Y02A50/30 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/42]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:VERFAHREN ZUR HEMMUNG DER EXPRESSION EINE ZIELGENS[2003/42]
English:METHOD FOR INHIBITING THE EXPRESSION OF A TARGET GENE[2003/42]
French:PROCEDE POUR INHIBER L'EXPRESSION D'UN GENE CIBLE[2003/42]
Entry into regional phase27.05.2003National basic fee paid 
27.05.2003Designation fee(s) paid 
27.05.2003Examination fee paid 
Examination procedure23.07.2002Request for preliminary examination filed
International Preliminary Examining Authority: EP
27.05.2003Amendment by applicant (claims and/or description)
27.05.2003Examination requested  [2003/42]
06.05.2004Despatch of a communication from the examining division (Time limit: M06)
05.11.2004Reply to a communication from the examining division
02.05.2005Communication of intention to grant the patent
08.08.2005Fee for grant paid
08.08.2005Fee for publishing/printing paid
12.10.2005Despatch of a communication from the examining division (Time limit: M02)
03.11.2005Reply to a communication from the examining division
Opposition(s)Opponent(s)01  28.02.2007  09.03.2007  ADMISSIBLE
Sirna Therapeutics
1700 Owens Street 4th Floor
San Francisco CA 94158 / US
Opponents representative
Weber, Martin, et al, et al
Jones Day
Prinzregentenstrasse 11
80538 München / DE
 [2012/45]
Former [2007/15]
Opponent(s)01  28.02.2007   
Sirna Therapeutics
1700 Owens Street 4th Floor
San Francisco CA 94158 / US
Opponents representative
Bezzubova, Olga, et al, et al
Uexküll & Stolberg Patentanwälte Thomas-Wimmer-Ring 9
D-80539 München / DE
05.04.2007Invitation to proprietor to file observations on the notice of opposition
15.10.2007Reply of patent proprietor to notice(s) of opposition
14.07.2009Date of oral proceedings
25.08.2009Despatch of minutes of oral proceedings
25.08.2009Date of despatch of rejection of opposition
11.03.2014Legal effect of rejection of opposition [2014/18]
Appeal following opposition23.10.2009Appeal received No.  T2104/09
04.01.2010Statement of grounds filed
11.03.2014Result of appeal procedure: appeal of the opponent withdrawn
Fees paidRenewal fee
27.05.2003Renewal fee patent year 03
14.12.2004Renewal fee patent year 04
08.12.2005Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY31.05.2006
FI31.05.2006
NL31.05.2006
TR31.05.2006
DK31.08.2006
SE31.08.2006
GR01.09.2006
ES11.09.2006
PT31.10.2006
IT09.01.2007
LU09.01.2007
BE31.01.2007
FR31.01.2007
MC31.01.2007
[2009/42]
Former [2009/41]CY31.05.2006
FI31.05.2006
NL31.05.2006
DK31.08.2006
SE31.08.2006
GR01.09.2006
ES11.09.2006
PT31.10.2006
IT09.01.2007
LU09.01.2007
BE31.01.2007
FR31.01.2007
MC31.01.2007
Former [2009/38]CY31.05.2006
FI31.05.2006
NL31.05.2006
DK31.08.2006
SE31.08.2006
GR01.09.2006
ES11.09.2006
PT31.10.2006
LU09.01.2007
BE31.01.2007
FR31.01.2007
MC31.01.2007
Former [2009/27]FI31.05.2006
NL31.05.2006
DK31.08.2006
SE31.08.2006
GR01.09.2006
ES11.09.2006
PT31.10.2006
BE31.01.2007
FR31.01.2007
MC31.01.2007
Former [2008/21]FI31.05.2006
NL31.05.2006
DK31.08.2006
SE31.08.2006
GR01.09.2006
ES11.09.2006
PT31.10.2006
BE31.01.2007
MC31.01.2007
Former [2008/04]FI31.05.2006
NL31.05.2006
DK31.08.2006
SE31.08.2006
ES11.09.2006
PT31.10.2006
BE31.01.2007
MC31.01.2007
Former [2007/48]FI31.05.2006
NL31.05.2006
DK31.08.2006
SE31.08.2006
ES11.09.2006
PT31.10.2006
MC31.01.2007
Former [2007/19]FI31.05.2006
NL31.05.2006
DK31.08.2006
SE31.08.2006
ES11.09.2006
PT31.10.2006
Former [2007/12]FI31.05.2006
DK31.08.2006
SE31.08.2006
ES11.09.2006
PT31.10.2006
Former [2007/11]FI31.05.2006
DK31.08.2006
SE31.08.2006
ES11.09.2006
Former [2006/52]FI31.05.2006
SE31.08.2006
ES11.09.2006
Former [2006/50]SE31.08.2006
ES11.09.2006
Former [2006/48]SE31.08.2006
Cited inInternational search[A]WO9401550  (HYBRIDON INC [US], et al);
 [Y]WO9805770  (DEUTCHES KREBSFORSCHUNGSZENTRU [DE], et al) [Y] 1-240 * the whole document *;
 [Y]WO9932619  (CARNEGIE INST OF WASHINGTON [US], et al) [Y] 1-240 * the whole document *;
 [X]WO0044895  (KREUTZER ROLAND [DE], et al) [X] 1-240 * the whole document *;
 [Y]WO0044914  (MED COLLEGE GEORGIA RES INST [US], et al) [Y] 1-240 * the whole document *;
 [Y]  - ZAMORE PHILLIP D ET AL, "RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals", CELL, CELL PRESS, CAMBRIDGE, NA, US, (20000331), vol. 101, no. 1, ISSN 0092-8674, pages 25 - 33, XP002208683 [Y] 1-240 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0092-8674(00)80620-0
 [Y]  - BASS BRENDA L, "Double-stranded RNA as a template for gene silencing", CELL, CELL PRESS, CAMBRIDGE, NA, US, (20000428), vol. 101, no. 3, ISSN 0092-8674, pages 235 - 238, XP002194756 [Y] 1-240 * figure 1 *

DOI:   http://dx.doi.org/10.1016/S0092-8674(02)71133-1
 [Y]  - UHLMANN E ET AL, "ANTISENSE OLIGONUCLEOTIDES: A NEW THERAPEUTIC PRINCIPLE", CHEMICAL REVIEWS, AMERICAN CHEMICAL SOCIETY. EASTON, US, (19900601), vol. 90, no. 4, ISSN 0009-2665, pages 543 - 584, XP000141412 [Y] 20-30,60-70,99-109,140-150,180-190,219-229 * the whole document *

DOI:   http://dx.doi.org/10.1021/cr00102a001
 [Y]  - PARRISH S., FLEENOR J., ET AL., "Functional Anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference.", MOL. CELL, (200011), vol. 6, pages 1077 - 187, XP002226361 [Y] 1-240 * the whole document *

DOI:   http://dx.doi.org/10.1016/S1097-2765(00)00106-4
 [YP]  - AMBROS VICTOR, "Dicing up RNAs", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, (20010803), vol. 293, no. 5531, ISSN 0036-8075, pages 811 - 813, XP002183122 [YP] 1-240 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.1064400
 [YP]  - ELBASHIR SAYDA M ET AL, "RNA interference is mediated by 21- and 22-nucleotide RNAs", GENES AND DEVELOPMENT, COLD SPRING HARBOR LABORATORY PRESS, NEW YORK, US, (20010115), vol. 15, no. 2, ISSN 0890-9369, pages 188 - 200, XP002204651 [YP] 1-240 * the whole document *

DOI:   http://dx.doi.org/10.1101/gad.862301
ExaminationWO0175164
 WO0244321
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.