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EP About this file: EP1515981

EP1515981 - NOVEL MOLECULES OF THE PYRIN/NBS/LRR PROTEIN FAMILY AND USES THEREOF [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 21.12.2007 Database last updated on 18.11.2024
Most recent event Tooltip	21.12.2007	Application deemed to be withdrawn	published on 23.01.2008 [2008/04]
Applicant(s)	For all designated states MILLENNIUM PHARMACEUTICALS, INC. 75 Sidney Street Cambridge, MA 02139-4169 / US
	For all designated states Wyeth Five Giralda Farms Madison, NJ 07940 / US
	[N/P]
Former [2005/12]	For all designated states MILLENNIUM PHARMACEUTICALS, INC. 75 Sidney Street Cambridge, MA 02139-4169 / US
	For all designated states Wyeth Five Giralda Farms Madison, New Jersey 07940 / US
Inventor(s)	01 / BERTIN, John 475 Arsenal Street, Apt. 1 Watertown, MA 02172 / US
	02 / WANG, Weiye 168 Thoreau Drive Plainsboro, NJ 08536 / US
	03 / BLATCHER, Maria 720 Cox Road Moorestown, NJ 08057 / US
	[2005/12]
Representative(s)	Schnappauf, Georg, et al ZSP Patentanwälte PartG mbB Hansastraße 32 80686 München / DE
	[N/P]
Former [2006/10]	Schnappauf, Georg, et al Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6 81679 München / DE
Former [2005/12]	Grund, Martin, Dr., et al Dr. Volker Vossius, Patentanwaltskanzlei, Geibelstrasse 6 81679 München / DE
Application number, filing date	02713524.3	31.01.2002
	[2005/12]
	WO2002US02967
Priority number, date	US20010265231P	31.01.2001 Original published format: US 265231 P
	US20010318645P	10.09.2001 Original published format: US 318645 P
	[2005/12]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO02061049
	Date:	08.08.2002
	Language:	EN
	[2002/32]
	Type:	A2 Application without search report
	No.:	EP1515981
	Date:	23.03.2005
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 08.08.2002 takes the place of the publication of the European patent application.
	[2005/12]
Search report(s)	International search report - published on:	US	13.01.2005
	(Supplementary) European search report - dispatched on:	EP	09.06.2004
Classification	IPC:	C07H17/00, C07K16/18, C12N15/12, G01N33/53, C12Q1/68	[2005/12]
	CPC:	C07K14/47 (EP,US); A61K38/00 (EP,US)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2005/12]
Title	German:	NEUE MOLEKÜLE DER PYRIN/NBS/LRR-PROTEINFAMILIE UND DEREN VERWENDUNGEN	[2005/12]
	English:	NOVEL MOLECULES OF THE PYRIN/NBS/LRR PROTEIN FAMILY AND USES THEREOF	[2005/12]
	French:	NOUVELLES MOLECULES DE LA FAMILLE DES PROTEINES PYRIN/NBS/LRR ET LEURS UTILISATIONS	[2005/12]
Entry into regional phase	05.08.2003	National basic fee paid
	05.08.2003	Search fee paid
	05.08.2003	Designation fee(s) paid
	05.08.2003	Examination fee paid
Examination procedure	05.08.2003	Examination requested [2005/12]
	30.09.2003	Amendment by applicant (claims and/or description)
	28.08.2004	Request for preliminary examination filed International Preliminary Examining Authority: US
	01.08.2007	Application deemed to be withdrawn, date of legal effect [2008/04]
	05.09.2007	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2008/04]
Fees paid	Renewal fee
	26.01.2004	Renewal fee patent year 03
	07.01.2005	Renewal fee patent year 04
	09.01.2006	Renewal fee patent year 05
	Penalty fee
	Additional fee for renewal fee
	31.01.2007	06 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[PX]WO0161005 (MILLENNIUM PHARM INC [US], et al) [PX] 5 * the whole document *;
		[PX]WO0175067 (HYSEQ INC [US], et al) [PX] 1-18* 91,08% identity in 213 aa overlap (total 655 aa) of SEQ ID NO: 38153 with SEQ ID NO: 13; 96,5% identity in 653 nt overlap (total 1968 nt) of SEQ ID NO: 7785 with SEQ ID NO: 12 *;
		[PX]WO0192527 (INCYTE GENOMICS INC [US], et al) [PX] 1-18 * 99,85% identity in 655 aa overlap (total 655 aa) of SEQ ID NO: 2 with SEQ ID NO: 13; 99,95% identity in 1986 nt overlap (total 1968 nt) of SEQ ID NO: 5 with SEQ ID NO: 12 of the application *;
		[E]WO0214500 (CHIRON CORP [US], et al) [E] 5,16 * SEQ ID NO: 4731 shows 88,095% identity in 378 nt overlap (total 1506 nt) with SEQ ID NO: 1 of the present application *;
		[E]WO0232955 (US GOV HEALTH & HUMAN SERV [US], et al) [E] 1-18 * 95,9% identity in 1145 aa overlap (total 1344 aa) of SEQ ID NO:24 with SEQ ID NO: 6; 99,9% identity of SEQ ID NO:23 in 2908 nt overlap (total 4035 nt) with SEQ ID NO: 5 of the application *;
		[E]WO0240668 (APOTECH RES & DEV LTD [CH], et al) [E] 1-18 * NALP9/Py13: 96,97% identity in 96 aa (total 501 aa); NALP5/Py8-hs: 91,6% identity in 1203 aa (total 1344 aa); NALP10/Py14: 84,75% identity in 577 aa (total 655 aa) with SEQ ID NO: 2,6,13 *;
		[E]WO0248362 (INCYTE GENOMICS INC [US], et al) [E] 1-18 * 95,16% identity of SEQ ID NO: 1 in 1158 aa overlap (total 1344 aa) with SEQ ID NO: 6; 99,84% identity of SEQ ID NO: 3 in 3025 nt overlap (total 4035 nt) with SEQ ID NO: 5 of the application *;
		[E]EP1285964 (SCHERING AG [DE]) [E] 1-18 * 95,16% identity in 1158 aa overlap (total 1344 aa) of SEQ ID NO: 2 with SEQ ID NO: 6; 99,84% identity in 3025 nt overlap (total 4035 nt) of SEQ ID NO: 1 with SEQ ID NO: 5 of the application *;
		[X] - ZHAO, S. ET AL., "CITBI-E1-2565K18.TF CITBI-E1 homo sapiens genomic clone 2565K18, genomic survey sequence", EMBL, (19990325), Database accession no. AQ424752, URL: EBI, XP002269231 [X] 5,16 * abstract *
		[X] - DIAS NETA, E. ET AL., "IL2-UT0074-040900-153-G02 UT0074 homo sapiens cDNA, mRNA sequence", EMBL, (20001130), Database accession no. BF380801, URL: EBI, XP002269232 [X] 3,5,16 * abstract *
		[X] - BERTIN J ET AL, "THE PYRIN DOMAIN: A NOVEL MOTIF FOUND IN APOPTOSIS AND INFLAMMATION PROTEINS", CELL DEATH AND DIFFERENTIATION, EDWARD ARNOLD, OXFORD, GB, (200012), vol. 12, no. 7, ISSN 1350-9047, pages 1273 - 1274, XP008006072 [X] 1-18 * the whole document * DOI: http://dx.doi.org/10.1038/sj.cdd.4400774
		[A] - MASUMOTO J ET AL, "Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (20010126), vol. 280, no. 3, ISSN 0006-291X, pages 652 - 655, XP002213123 DOI: http://dx.doi.org/10.1006/bbrc.2000.4190
	International search	[XT]WO0232955 (US GOV HEALTH & HUMAN SERV [US], et al);
		[XT]WO0240668 (APOTECH RES & DEV LTD [CH], et al);
		[XT] - TONG ET AL, "A human homologue of mouse Mater, a maternal effect gene essential for easerly embryonic develoment.", HUMAN REPRODUCTION, vol. 17, no. 4, pages 903 - 911, XP002984425 DOI: http://dx.doi.org/10.1093/humrep/17.4.903

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