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Extract from the Register of European Patents

EP About this file: EP1366149

EP1366149 - MODIFIED TARGET ENZYMES HAVING CATALYTIC TRIADS AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.04.2013
Database last updated on 16.11.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): LU		published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
Danisco US Inc.
925 Page Mill Road
Palo Alto, CA 94304 / US
[2012/19]
Former [2003/49]For all designated states
Genencor International, Inc.
926 Page Mill Road
Palo Alto, California 94304 / US
Inventor(s)01 / SHAW, Andrew
2560 Hyde Street
San Francisco, CA 94109 / US
 [2003/49]
Representative(s)Kiddle, Simon John, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2012/22]Kiddle, Simon John, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Former [2003/49]Kiddle, Simon John, et al
Mewburn Ellis, York House, 23 Kingsway
London WC2B 6HP / GB
Application number, filing date02717393.904.02.2002
[2003/49]
WO2002US03347
Priority number, dateUS20010268347P12.02.2001         Original published format: US 268347 P
[2003/49]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO02064738
Date:22.08.2002
Language:EN
[2002/34]
Type: A2 Application without search report 
No.:EP1366149
Date:03.12.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 22.08.2002 takes the place of the publication of the European patent application.
[2003/49]
Type: B1 Patent specification 
No.:EP1366149
Date:30.05.2012
Language:EN
[2012/22]
Search report(s)International search report - published on:US20.02.2003
(Supplementary) European search report - dispatched on:EP14.07.2008
ClassificationIPC:A61K38/47, C11D3/386, C12N9/14, C12N9/42
[2008/33]
CPC:
C12N9/2437 (EP,US); A61K38/47 (EP,US); C11D3/386 (EP,US);
C11D3/38645 (EP,US); C12N9/14 (EP,US); C12Y302/01004 (EP,US)
Former IPC [2003/49]C12N9/14, C12N9/42
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/49]
TitleGerman:MODIFIZIERTE ZIELENZYME MIT KATALYTISCHEN TRIADEN UND DEREN VERWENDUNG[2003/49]
English:MODIFIED TARGET ENZYMES HAVING CATALYTIC TRIADS AND USES THEREOF[2003/49]
French:ENZYMES CIBLES MODIFIEES RENFERMANT DES TRIADES CATALYTIQUES ET UTILISATIONS DE CES DERNIERES[2003/49]
Entry into regional phase01.09.2003National basic fee paid 
01.09.2003Search fee paid 
01.09.2003Designation fee(s) paid 
01.09.2003Examination fee paid 
Examination procedure09.09.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
01.09.2003Amendment by applicant (claims and/or description)
01.09.2003Examination requested  [2003/49]
26.01.2009Despatch of a communication from the examining division (Time limit: M06)
09.09.2009Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
12.11.2009Reply to a communication from the examining division
23.02.2011Despatch of a communication from the examining division (Time limit: M06)
20.07.2011Reply to a communication from the examining division
29.11.2011Communication of intention to grant the patent
23.03.2012Fee for grant paid
23.03.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.01.2009
Opposition(s)01.03.2013No opposition filed within time limit [2013/19]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
12.11.2009Request for further processing filed
12.11.2009Full payment received (date of receipt of payment)
Fees paidRenewal fee
12.02.2004Renewal fee patent year 03
14.02.2005Renewal fee patent year 04
14.02.2006Renewal fee patent year 05
14.02.2007Renewal fee patent year 06
13.02.2008Renewal fee patent year 07
26.02.2009Renewal fee patent year 08
24.02.2010Renewal fee patent year 09
23.02.2011Renewal fee patent year 10
24.02.2012Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
TR30.05.2012
GR31.08.2012
ES10.09.2012
PT01.10.2012
IE04.02.2013
LU04.02.2013
CH28.02.2013
LI28.02.2013
MC28.02.2013
[2015/34]
Former [2015/32]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
TR30.05.2012
GR31.08.2012
ES10.09.2012
PT01.10.2012
IE04.02.2013
CH28.02.2013
LI28.02.2013
MC28.02.2013
Former [2014/07]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
GR31.08.2012
ES10.09.2012
PT01.10.2012
IE04.02.2013
CH28.02.2013
LI28.02.2013
MC28.02.2013
Former [2013/48]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
GR31.08.2012
ES10.09.2012
PT01.10.2012
CH28.02.2013
LI28.02.2013
MC28.02.2013
Former [2013/42]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
GR31.08.2012
ES10.09.2012
PT01.10.2012
MC28.02.2013
Former [2013/22]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
GR31.08.2012
ES10.09.2012
PT01.10.2012
Former [2013/13]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
GR31.08.2012
PT01.10.2012
Former [2013/11]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
IT30.05.2012
NL30.05.2012
SE30.05.2012
GR31.08.2012
Former [2013/08]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
NL30.05.2012
SE30.05.2012
GR31.08.2012
Former [2013/07]AT30.05.2012
BE30.05.2012
CY30.05.2012
FI30.05.2012
SE30.05.2012
GR31.08.2012
Former [2013/04]BE30.05.2012
CY30.05.2012
FI30.05.2012
SE30.05.2012
GR31.08.2012
Former [2012/50]CY30.05.2012
FI30.05.2012
SE30.05.2012
GR31.08.2012
Former [2012/49]CY30.05.2012
FI30.05.2012
SE30.05.2012
Former [2012/48]FI30.05.2012
SE30.05.2012
Documents cited:Search[X]  - IENGAR P ET AL, "Knowledge-based modeling of the serine protease triad into non-proteases", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB, (19990801), vol. 12, no. 8, ISSN 0269-2139, pages 649 - 655, XP002984856 [X] 1-26 * abstract *

DOI:   http://dx.doi.org/10.1093/protein/12.8.649
 [X]  - LOWE M E, "Mutation of the catalytic site Asp-177 to Glu-177 in human pancreatic lipase produces an active lipase with increased sensitivity to proteases", BIOCHIMICA ET BIOPHYSICA ACTA - LIPIDS AND LIPID METABOLISM, ELSEVIER SCIENCE BV. AMSTERDAM, NL, (19960726), vol. 1302, no. 2, ISSN 0005-2760, pages 177 - 183, XP009102451 [X] 1-26 * abstract *

DOI:   http://dx.doi.org/10.1016/0005-2760(96)00058-6
International search[Y]EP0739982  (GENENCOR INT [US]);
 [Y]  - DAVIES ET AL., "Structure of the bacillus agaradherans family 5 endoglucanase at 1.6 A and its celobiose complex at 2.0 resolution", BIOCHEMISTRY, (1998), vol. 37, pages 1926 - 1932, XP002958212

DOI:   http://dx.doi.org/10.1021/bi972162m
 [Y]  - WANG ET AL., "Glu280 is te nucleophile in the active site of clostridium thermocellum Ce1C, a family A Endo-Beth-1,4-glucanase", J. BIOL. CHEM., (19930705), vol. 268, no. 19, pages 14096 - 14102, XP002958213
 [AP]  - SHIRAI ET AL., "Crystal structure of alkaline cellulase K: insight into the alkaline adaptation of an industrial enzyme", JOURNAL MOLECULAR BIOLOGY, (200107), vol. 310, pages 1079 - 1087, XP002958214

DOI:   http://dx.doi.org/10.1006/jmbi.2001.4835
 [A]  - DESANTIS ET AL., "Chemical modifications at a single site can induce significant shifts in tne pH profiles of a serine protease", J. AM. CHEM. SOC., (1998), vol. 120, pages 8582 - 8586, XP002918545

DOI:   http://dx.doi.org/10.1016/0022-2836(92)90234-B
 [A]  - DODSON ET AL., "Catalytic triads and their relatives", TIBS, (1998), vol. 23, no. 9, pages 347 - 352, XP004146829

DOI:   http://dx.doi.org/10.1016/S0968-0004(98)01254-7
 [A]  - BEGUIN P., "Molecular biology of cellulose degradation", ANN. REV. MICROBIOL., (1990), vol. 44, pages 219 - 248, XP002958215

DOI:   http://dx.doi.org/10.1146/annurev.mi.44.100190.001251
 [T]  - SHAW ET AL., "A novel combination of two classic catalytic schemes", J. MOL. BIOL., (200207), vol. 320, pages 303 - 309, XP002958216

DOI:   http://dx.doi.org/10.1016/S0022-2836(02)00387-X
by applicantEP0739982
    - VILLAFRANCA ET AL., SCIENCE, (1983), vol. 222, pages 782 - 788
    - PERRY ET AL., SCIENCE, (1984), vol. 226, pages 555 - 557
    - ESTELL ET AL., J. BIOL. CHEM, (1985), vol. 260, pages 6518 - 6521
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    - IENGAR ET AL., PROTEIN ENGINEERING, (1999), vol. 12, no. 8, pages 649 - 655
    - LOWE, BIOCHIMICA ET BIOPHYSICA ACTA, (1996), vol. 1302, pages 177 - 183
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.