Extract from the Register of European Patents

EP About this file: EP1394174

EP1394174 - PROCESS FOR PRODUCING METHYLCOBALAMIN [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.09.2016
Database last updated on 14.03.2026
Most recent event   Tooltip13.07.2018Lapse of the patent in a contracting state
New state(s): CY, LU, TR
published on 15.08.2018  [2018/33]
Applicant(s)For all designated states
Eisai R&D Management Co., Ltd.
6-10, Koishikawa 4-chome
Bunkyo-ku
Tokyo 112-8088 / JP
[N/P]
Former [2015/46]For all designated states
Eisai R&D Management Co., Ltd.
6-10, Koishikawa 4-chome Bunkyo-ku
Tokyo 112-8088 / JP
Former [2007/08]For all designated states
Eisai R&D Management Co., Ltd.
6-10, Koishikawa, 4-chome Bunkyo-ku
Tokyo 112-8088 / JP
Former [2004/10]For all designated states
Eisai Co., Ltd.
6-10, Koishikawa 4-chome, Bunkyo-ku
Tokyo 112-8088 / JP
Inventor(s)01 / HISATAKE, Yoshihiko
63-15, Kyuchu
Kashima-shi, Ibaraki 314-0031 / JP
02 / TANAKA, Takuo
3428-130, Shitte, Kamisumachi
Kashima-gun, Ibaraki 314-0115 / JP
03 / TSURUGI, Tomio
1-1044-130, Toyosatodai
Choshi-shi, Chiba 288-0874 / JP
04 / KURODA, Hiroshi
2-13-10, Fukashibaminami, Kamisumachi
Kashima-gun, Ibaraki 314-0142 / JP
 [2004/10]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2015/46]
Former [2004/10]HOFFMANN - EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date02733293.104.06.2002
[2004/10]
WO2002JP05510
Priority number, dateJP2001016910705.06.2001         Original published format: JP 2001169107
[2004/10]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO02098896
Date:12.12.2002
Language:EN
[2002/50]
Type: A1 Application with search report 
No.:EP1394174
Date:03.03.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 12.12.2002 takes the place of the publication of the European patent application.
[2004/10]
Type: B1 Patent specification 
No.:EP1394174
Date:11.11.2015
Language:EN
[2015/46]
Search report(s)International search report - published on:JP12.12.2002
(Supplementary) European search report - dispatched on:EP25.07.2007
ClassificationIPC:C07H23/00
[2004/10]
CPC:
C07H23/00 (EP,KR,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2015/46]
Former [2004/10]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE,  TR 
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON METHYLCOBALAMIN[2004/10]
English:PROCESS FOR PRODUCING METHYLCOBALAMIN[2004/10]
French:PROCEDE DE PRODUCTION DE METHYLCOBALAMINE[2004/10]
Entry into regional phase03.11.2003Translation filed 
03.11.2003National basic fee paid 
03.11.2003Search fee paid 
03.11.2003Designation fee(s) paid 
03.11.2003Examination fee paid 
Examination procedure22.10.2002Request for preliminary examination filed
International Preliminary Examining Authority: JP
03.11.2003Examination requested  [2004/10]
14.12.2004Amendment by applicant (claims and/or description)
21.12.2010Despatch of a communication from the examining division (Time limit: M04)
28.03.2011Reply to a communication from the examining division
10.06.2015Communication of intention to grant the patent
28.09.2015Fee for grant paid
28.09.2015Fee for publishing/printing paid
28.09.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.12.2010
Opposition(s)12.08.2016No opposition filed within time limit [2016/42]
Fees paidRenewal fee
25.06.2004Renewal fee patent year 03
29.06.2005Renewal fee patent year 04
28.06.2006Renewal fee patent year 05
26.06.2007Renewal fee patent year 06
26.06.2008Renewal fee patent year 07
25.06.2009Renewal fee patent year 08
31.03.2010Renewal fee patent year 09
27.06.2011Renewal fee patent year 10
31.03.2012Renewal fee patent year 11
20.06.2013Renewal fee patent year 12
31.03.2014Renewal fee patent year 13
19.06.2015Renewal fee patent year 14
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Lapses during opposition  TooltipAT11.11.2015
BE11.11.2015
CY11.11.2015
DK11.11.2015
FI11.11.2015
IT11.11.2015
MC11.11.2015
NL11.11.2015
SE11.11.2015
TR11.11.2015
GR12.02.2016
PT11.03.2016
GB04.06.2016
IE04.06.2016
LU04.06.2016
CH30.06.2016
LI30.06.2016
[2018/29]
Former [2017/23]AT11.11.2015
BE11.11.2015
DK11.11.2015
FI11.11.2015
IT11.11.2015
MC11.11.2015
NL11.11.2015
SE11.11.2015
GR12.02.2016
PT11.03.2016
GB04.06.2016
IE04.06.2016
CH30.06.2016
LI30.06.2016
Former [2017/23]AT11.11.2015
BE11.11.2015
DK11.11.2015
FI11.11.2015
IT11.11.2015
MC11.11.2015
NL11.11.2015
SE11.11.2015
GR12.02.2016
PT11.03.2016
GB04.06.2016
CH30.06.2016
LI30.06.2016
Former [2017/07]AT11.11.2015
BE11.11.2015
DK11.11.2015
FI11.11.2015
IT11.11.2015
MC11.11.2015
NL11.11.2015
SE11.11.2015
GR12.02.2016
PT11.03.2016
Former [2017/03]AT11.11.2015
BE11.11.2015
DK11.11.2015
FI11.11.2015
IT11.11.2015
NL11.11.2015
SE11.11.2015
GR12.02.2016
PT11.03.2016
Former [2016/39]AT11.11.2015
DK11.11.2015
FI11.11.2015
IT11.11.2015
NL11.11.2015
SE11.11.2015
GR12.02.2016
PT11.03.2016
Former [2016/24]AT11.11.2015
FI11.11.2015
IT11.11.2015
NL11.11.2015
SE11.11.2015
GR12.02.2016
PT11.03.2016
Former [2016/23]IT11.11.2015
NL11.11.2015
SE11.11.2015
Former [2016/21]IT11.11.2015
Documents cited:Search  No further relevant documents disclosed
International search[Y]   AMIJEE M. ET AL.: "Direct on-column derivatisation in gas chromatography II. Comparison of various on-column methylation reagents and the development of a new selective methylation reagent", JOURNAL OF CHROMATOGRPAHY, vol. 738, 1996, pages 43 - 55, XP004038973 [Y]

DOI:   http://dx.doi.org/10.1016/0021-9673(96)00087-8
 [Y]   DATABASE CAPLUS [online] MATOS J.R. ET AL.: "S-adenosylmethionine: studies on chemical and enzymic synthesis", XP002954480, accession no. STN Database accession no. 1987:210255 [Y]
 [Y]   BIOTECHNOL. APPL. BIOCHEM., vol. 9, no. 1, 1987, pages 39 - 52
 [A]   BYRNE B. ET AL.: "The preparation of trimethylsulfonium chloride from methyl chloroformate and dimethyl sulfide", TETRAHEDRON LETTERS, vol. 27, no. 11, 1986, pages 1233 - 1236, XP002954481 [A]

DOI:   http://dx.doi.org/10.1016/S0040-4039(00)84225-2
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