Extract from the Register of European Patents

EP About this file: EP1404699

EP1404699 - ANTISENSE MODULATION OF SRC-C EXPRESSION [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  25.03.2005
Database last updated on 14.03.2026
Most recent event   Tooltip13.11.2009Change - representativepublished on 16.12.2009  [2009/51]
Applicant(s)For all designated states
Isis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
[N/P]
Former [2004/15]For all designated states
ISIS PHARMACEUTICALS, INC.
2292 Faraday Avenue
Carlsbad, CA 92008 / US
Inventor(s)01 / BENNETT, Frank, C.
1347 Cassins Street
Carlsbad, CA 92008 / US
02 / WATT, Andrew, T.
1500 Shadowridge Drive, Apt 154
Vista, CA 92083 / US
 [2004/15]
Representative(s)Hallybone, Huw George, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2009/51]Hallybone, Huw George, et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Former [2004/15]Hallybone, Huw George, et al
Carpmaels and Ransford, 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date02747842.916.05.2002
[2004/15]
WO2002US15684
Priority number, dateUS2001086047318.05.2001         Original published format: US 860473
[2004/15]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO02095053
Date:28.11.2002
Language:EN
[2002/48]
Type: A2 Application without search report 
No.:EP1404699
Date:07.04.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 28.11.2002 takes the place of the publication of the European patent application.
[2004/15]
Search report(s)International search report - published on:US01.05.2003
ClassificationIPC:C07H21/02, C07H21/04, A61K48/00, C12N15/85, C12N15/86, C12Q1/68, C12P19/34
[2004/15]
CPC:
C12N15/1137 (EP,US); A61K38/00 (EP,US); C12N2310/315 (EP,US);
C12N2310/321 (EP,US); C12N2310/3341 (EP,US); C12N2310/341 (EP,US);
C12N2310/346 (EP,US); Y02P20/582 (EP,US) (-)
C-Set:
C12N2310/321, C12N2310/3525 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/15]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:ANTISENSE-MODULATION DER SRC-C-EXPRESSION[2004/15]
English:ANTISENSE MODULATION OF SRC-C EXPRESSION[2004/15]
French:MODULATION ANTISENS DE L'EXPRESSION DES SRC-C[2004/15]
Entry into regional phase15.12.2003National basic fee paid 
15.12.2003Search fee paid 
15.12.2003Designation fee(s) paid 
15.12.2003Examination fee paid 
Examination procedure13.12.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
15.12.2003Amendment by applicant (claims and/or description)
15.12.2003Examination requested  [2004/15]
09.02.2005Application withdrawn by applicant  [2005/19]
Fees paidRenewal fee
15.12.2003Renewal fee patent year 03
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Cited inInternational search[X]   CHELLAIAH ET AL.: "c-Scr is required for stimulation of gelsolin-associated phosphatidylinositol 3-kinase", THE JOURNAL OF BOLOGICAL CHEMISTRY, vol. 273, no. 19, 8 May 1998 (1998-05-08), pages 11908 - 11916, XP002956434 [X]

DOI:   http://dx.doi.org/10.1074/jbc.273.19.11908
 [X]   TANAKA ET AL.: "c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption", NATURE, vol. 383, 10 October 1996 (1996-10-10), pages 528 - 531, XP002956435 [X]

DOI:   http://dx.doi.org/10.1038/383528a0
 [X]   STALEY ET AL.: "Decreased turmorigenicity of a human colon adenocarcinoma cell line by an antisense expression vector specific for c-Src", CELL GROWTH AND DIFFERENTIATION, vol. 8, March 1997 (1997-03-01), pages 269 - 274, XP002956436 [X]
 [X]   NARUSE ET AL.: "Uni-axial cyclic stretch induces c-scr activation and translocation in human endothelial cells via SA channel activation", FEBS LETTERS, vol. 441, December 1998 (1998-12-01), pages 111 - 115, XP004258882 [X]

DOI:   http://dx.doi.org/10.1016/S0014-5793(98)01528-2
 [X]   MARZIA ET AL.: "Decreased c-Scr expression enhances osteoblast differentation and bone formation", THE JOURNAL OF CELL BIOLOGY, vol. 151, no. 2, 16 October 2000 (2000-10-16), pages 311 - 320, XP002956437 [X]

DOI:   http://dx.doi.org/10.1083/jcb.151.2.311
 [A]   BRANCH A.D.: "A good antisense is hard to find", TIBS, vol. 23, February 1998 (1998-02-01), pages 45 - 50, XP000938938 [A]

DOI:   http://dx.doi.org/10.1016/S0968-0004(97)01155-9
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