EP1373491 - PURIFIED LACTASE [Right-click to bookmark this link] | Status | Patent revoked Status updated on 24.06.2022 Database last updated on 31.08.2024 | |
Former | The patent has been granted Status updated on 10.09.2019 | Most recent event Tooltip | 29.07.2022 | Lapse of the patent in a contracting state New state(s): GB, IE | published on 31.08.2022 [2022/35] | Applicant(s) | For all designated states DSM IP Assets B.V. Het Overloon 1 6411 TE Heerlen / NL | [2016/01] |
Former [2004/01] | For all designated states DSM IP Assets B.V. Het Overloon 1 6411 TE Heerlen / NL | Inventor(s) | 01 /
BECKHOVEN VAN, Rudolf Franciscus Wilhelmus C. Hofwijkstraat 69 4834 EK Breda / NL | 02 /
PARIDON, VAN, Petrus, Andreas G.J. van der Veenstraat 15 NL-2264 DS Leidschendam / NL | [2004/01] | Representative(s) | dsm-firmenich IP P.O. Box 4 6100 AA Echt / NL | [N/P] |
Former [2016/01] | van Grieken-Plooster, Izabella Johanna, et al DSM Intellectual Property P.O. Box 4 6100 AA Echt / NL | ||
Former [2011/11] | Matulewicz, Emil Rudolf Antonius, et al DSM Intellectual Property P.O. Box 130 6100 AC Echt / NL | ||
Former [2004/01] | Matulewicz, Emil Rudolf Antonius, Dr., et al DSM N.V. Patents & Trademarks Department Office Delft 600-0240 P.O. Box 1 2600 MA Delft / NL | Application number, filing date | 02759791.3 | 03.04.2002 | [2004/01] | WO2002EP03680 | Priority number, date | EP20010000102 | 04.04.2001 Original published format: EP 01000102 | [2004/01] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO02081673 | Date: | 17.10.2002 | Language: | EN | [2002/42] | Type: | A1 Application with search report | No.: | EP1373491 | Date: | 02.01.2004 | Language: | EN | The application published by WIPO in one of the EPO official languages on 17.10.2002 takes the place of the publication of the European patent application. | [2004/01] | Type: | B1 Patent specification | No.: | EP1373491 | Date: | 30.12.2015 | Language: | EN | [2015/53] | Search report(s) | International search report - published on: | EP | 17.10.2002 | Classification | IPC: | A23C9/12, C12N9/38 | [2015/09] | CPC: |
A23C9/1206 (EP,US);
C12N9/2402 (EP,US);
C12N9/2471 (EP,US);
C12Y302/01023 (EP,US);
A23C2210/208 (EP,US);
C12Y302/01108 (EP,US)
|
Former IPC [2004/01] | C12N9/38, A23J1/18, A23J3/20, A23C9/14 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2016/01] |
Former [2004/01] | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR | Extension states | AL | 11.09.2003 | LT | 11.09.2003 | LV | 11.09.2003 | MK | 11.09.2003 | Title | German: | GEREINIGTE LACTASE | [2004/01] | English: | PURIFIED LACTASE | [2004/01] | French: | LACTASE PURIFIEE | [2004/01] | Entry into regional phase | 11.09.2003 | National basic fee paid | 11.09.2003 | Designation fee(s) paid | 11.09.2003 | Examination fee paid | Examination procedure | 01.10.2002 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 11.09.2003 | Examination requested [2004/01] | 20.02.2007 | Despatch of a communication from the examining division (Time limit: M06) | 13.08.2007 | Reply to a communication from the examining division | 24.04.2008 | Despatch of a communication from the examining division (Time limit: M04) | 26.05.2008 | Reply to a communication from the examining division | 20.10.2008 | Despatch of a communication from the examining division (Time limit: M04) | 16.02.2009 | Reply to a communication from the examining division | 10.09.2009 | Despatch of a communication from the examining division (Time limit: M06) | 04.03.2010 | Reply to a communication from the examining division | 20.11.2010 | Observations by third parties | 07.12.2010 | Despatch of a communication from the examining division (Time limit: M06) | 16.06.2011 | Reply to a communication from the examining division | 25.07.2011 | Observations by third parties | 30.12.2011 | Despatch of a communication from the examining division (Time limit: M06) | 09.07.2012 | Reply to a communication from the examining division | 14.06.2013 | Despatch of a communication from the examining division (Time limit: M04) | 16.10.2013 | Reply to a communication from the examining division | 16.01.2015 | Cancellation of oral proceeding that was planned for 29.01.2015 | 29.01.2015 | Date of oral proceedings (cancelled) | 24.07.2015 | Communication of intention to grant the patent | 05.11.2015 | Fee for grant paid | 05.11.2015 | Fee for publishing/printing paid | 05.11.2015 | Receipt of the translation of the claim(s) | Divisional application(s) | EP10176987.5 / EP2280065 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 20.02.2007 | Opposition(s) | Opponent(s) | 01
28.09.2016
06.10.2016
ADMISSIBLE Novozymes A/S Krogshøjvej 36 2880 Bagsværd / DK Opponent's representative Wichmann, Hendrik Wuesthoff & Wuesthoff Patentanwälte und Rechtsanwalt PartG mbB Schweigerstraße 2 81541 München / DE | 02
30.09.2016
06.10.2016
ADMISSIBLE DuPont Nutrition Biosciences ApS Langebrogade 1 P.O. Box 17 1001 Copenhagen K / DK Opponent's representative D Young & Co LLP, et al, et al 3 Noble Street London EC2V 7BQ / GB | 03
30.09.2016
06.10.2016
ADMISSIBLE Chr. Hansen A/S Bøge Allé 10-12 2970 Hørsholm / DK Opponent's representative Uexküll & Stolberg, et al, et al Partnerschaft von Patent- und Rechtsanwälten mbB Beselerstraße 4 22607 Hamburg / DE | [N/P] |
Former [2019/20] | |||
Opponent(s) | 01
28.09.2016
06.10.2016
ADMISSIBLE Novozymes A/S Krogshøjvej 36 2880 Bagsværd / DK Opponent's representative Wichmann, Hendrik Wuesthoff & Wuesthoff Patentanwälte PartG mbB Schweigerstraße 2 81541 München / DE | ||
02
30.09.2016
06.10.2016
ADMISSIBLE DuPont Nutrition Biosciences ApS Langebrogade 1 P.O. Box 17 1001 Copenhagen K / DK Opponent's representative D Young & Co LLP, et al, et al 120 Holborn London EC1N 2DY / GB | |||
03
30.09.2016
06.10.2016
ADMISSIBLE Chr. Hansen A/S Bøge Allé 10-12 2970 Hørsholm / DK Opponent's representative Uexküll & Stolberg, et al, et al Partnerschaft von Patent- und Rechtsanwälten mbB Beselerstraße 4 22607 Hamburg / DE | |||
Former [2016/45] | |||
Opponent(s) | 01
28.09.2016
06.10.2016
ADMISSIBLE Novozymes A/S Krogshøjvej 36 2880 Bagsværd / DK Opponent's representative Wichmann, Hendrik Wuesthoff & Wuesthoff Patentanwälte PartG mbB Schweigerstraße 2 81541 München / DE | ||
02
30.09.2016
06.10.2016
ADMISSIBLE DuPont Nutrition BioSciences ApS Langebrogade 1 P.O. Box 17 1001 Copenhagen K / DK Opponent's representative D Young & Co LLP, et al, et al 120 Holborn London EC1N 2DY / GB | |||
03
30.09.2016
06.10.2016
ADMISSIBLE Chr. Hansen A/S Bøge Allé 10-12 2970 Hørsholm / DK Opponent's representative Uexküll & Stolberg, et al, et al Partnerschaft von Patent- und Rechtsanwälten mbB Beselerstraße 4 22607 Hamburg / DE | 08.11.2016 | Invitation to proprietor to file observations on the notice of opposition | 20.03.2017 | Reply of patent proprietor to notice(s) of opposition | 06.06.2019 | Date of oral proceedings | 11.09.2019 | Despatch of minutes of oral proceedings | 11.09.2019 | Despatch of communication that the patent will be revoked | 13.06.2022 | Legal effect of revocation of patent [2022/30] | Appeal following opposition | 11.11.2019 | Appeal received No. T2991/19 | 19.12.2019 | Statement of grounds filed | 13.06.2022 | Result of appeal procedure: appeal of the proprietor withdrawn | Fees paid | Renewal fee | 26.04.2004 | Renewal fee patent year 03 | 20.04.2005 | Renewal fee patent year 04 | 26.04.2006 | Renewal fee patent year 05 | 27.04.2007 | Renewal fee patent year 06 | 25.04.2008 | Renewal fee patent year 07 | 29.04.2009 | Renewal fee patent year 08 | 26.04.2010 | Renewal fee patent year 09 | 25.04.2011 | Renewal fee patent year 10 | 28.03.2012 | Renewal fee patent year 11 | 12.04.2013 | Renewal fee patent year 12 | 25.03.2014 | Renewal fee patent year 13 | 10.04.2015 | Renewal fee patent year 14 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CY | 30.12.2015 | MC | 30.12.2015 | LU | 03.04.2016 | GB | 02.04.2022 | IE | 03.04.2022 | ES | 04.04.2022 | PT | 12.04.2022 | [2022/35] |
Former [2022/34] | CY | 30.12.2015 | |
MC | 30.12.2015 | ||
LU | 03.04.2016 | ||
ES | 04.04.2022 | ||
PT | 12.04.2022 | ||
Former [2018/29] | CY | 30.12.2015 | |
MC | 30.12.2015 | ||
LU | 03.04.2016 | ||
Former [2017/04] | LU | 03.04.2016 | Cited in | International search | [XY]WO0104276 (UNIV LIEGE [BE]) [X] 1-3,8,11-14,19 * Table I; page 12 * [Y] 4-7,9,10,15-18; | [XY]US4237230 (IIDA TAKAO, et al) [X] 1-3,8,11-14,19 * column 4, lines 1-13; example 3 * [Y] 4-7,9,10,15-18; | [X]US4007283 (CRISAN ELI V, et al) [X] 1-3,11,12 * column 4, lines 17-22 *; | [X]GB1306751 (BAXTER LABORATORIES INC) [X] 1-3,11,12 * example 4 *; | [YD]EP0145092 (GIST BROCADES NV [NL]) [YD] 4-7,9,10,15-18 * page 4, lines 33-39 *; | [X] - RAHIM AND LEE, "Production and characterization of beta galactosidase from psychrotrophic Bacillus subtilis KL88", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1991), XP002174412 [X] 1-3,11,12 * abstract * | [X] - HUSSEIN L. ET AL., "Reduction of Lactose in Milk by purified Lactase produced by Kluyveromyces lactis", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1989), XP002174413 [X] 1-3,10-12 * abstract * | [X] - PARK ET AL., "Production and characterization of beta galactosidase EC 3.2.1.23 from Aspergillus orizae", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1979), XP002174414 [X] 1-3,12 * abstract * | other | - DICKSON R.C. ET AL, "Purification and properties on an inducible beta-galactosidase isolated from the yeast Kluyveromyces lactis", JOURNAL OF BACTERIOLOGY, (197901), vol. 137, no. 1, pages 51 - 61, XP003028171 | - OPTIM(TM) GLYCERINE, "Viscosity of Aqueous Glycerine Solutions", DOW CHEMICAL COMPANY WEBSITE, (2010), page 1, URL: http://www.dow.com/glycerine/resources/table18.htm, (20101011), XP003028172 | - BECERRA M. ET AL, "Micro-scale purification of beta-galactosidase from Kluyveromyces lactis reveals that dimeric and tetrameric forms are active", BIOTECHNOLOGY TECHNIQUES, (199803), vol. 12, no. 3, pages 253 - 256, XP002378514 DOI: http://dx.doi.org/10.1023/A:1008885827560 | Opposition | EP0145092 | US5357852 | FR2500269 | US4612169 | EP0037667 | EP0026672 | US5821350 | US6146902 | GB1477087 | US4007283 | WO02081673 | US4237230 | US3919049 | US5283189 | EP0020781 | EP0919132 | US3753725 | - Declaration of Morten Krog Larsen | - CAVAILLE, D. et al., "characterization of galactosidase fro kluyveromyces lactis", Biotechnol. Appl. Biochem., (19950000), vol. 22, pages 55 - 64, XP055312198 | - WIDMER, F. et al., "galactosidase from aspergillus niger", Eur. J. Biochem., (19790000), vol. 100, pages 559 - 567, XP055312203 | - DAHLQVIST, A et al., "hydrolysis of lactose in milk and whey with minute amounts of lactase", J. Dairy Res., (19770000), vol. 44, pages 541 - 548, XP009157855 DOI: http://dx.doi.org/10.1017/S0022029900020495 | - MBUYI-KALALA, A et al., "separation and characterization of four enzyme forms of galactosidase from saccharomyces lactis", Eur. J. Biochem., (19880000), vol. 178, pages 437 - 443, XP055022811 DOI: http://dx.doi.org/10.1111/j.1432-1033.1988.tb14467.x | - DA SILVA, M. et al., "purification of microbial galactosidase from kluyveromyces fragilis by bioaffinity partitioning", T. Revista de Micobiologia, (19990000), vol. 30, pages 324 - 331, XP055312209 | - BECERRA, M. et al., "micro scale purification of galactosidase from kluyveromyces", Biotechnol. Techniques, (19980000), vol. 12, pages 253 - 256, XP002378514 DOI: http://dx.doi.org/10.1023/A:1008885827560 | - BECERRA, M et al., "dealing with different methods for kluyveromyces", Biological Procedures, (19980000), vol. 1, pages 48 - 58, XP002378487 DOI: http://dx.doi.org/10.1251/bpo4 | - STEERS, E. et al., "the purification of galactosidase from escheridia coli", J. Biol. Chem., (19710000), vol. 246, pages 196 - 200, XP055312215 | - MAHONEY et al., "Beta-D-Galactosidase", Encyclopedia of Dairy Sciences, (20020000), pages 907 - 914 | - DICKSON et al., Journal of Bacteriology, (19790000), vol. 137, no. 1, pages 51 - 61 | - WIDMER et al., "beta-Galactosidase from Aspergillus niger", Eur. J. Biochem, (19790000), vol. 100, pages 559 - 567 | - FCC, (19960701), pages 801 - 802 | - Voedingsmiddelentechnologie, (19800000), vol. 13, no. 23 | - Anonymous, "Melk met gereduceerd lactose gehalte", Voedingsmiddelentechnologie, (19800306), vol. 13, no. 5, page 23, XP055313331 | - RICHMOND et al., "Beta-Galactosidase: Review of Recent Research related to technological application, nutritional concerns, and immobilization", J. Dairy Sci, (19810900), vol. 64, no. 9, pages 1759 - 1771, XP001314507 | - MAHONEY et al., "Purification and physicochemical properties of Ã?- galactosidase from Kluyveromyces fragilis", J. Food Sci, (19780000), vol. 43, pages 584 - 591, XP055313346 | - STEERS et al., "The purification of Beta-galactosidase from Escherichia coli by affinity chromatography", JBC, (19710000), vol. 246, pages 196 - 200, XP055313346 | - BECERRA M et al., "Dealing with different methods for Kluyveromyces lactis beta-galactosidase purification", Biological Procedures online, (19980514), vol. 1, no. 1, pages 48 - 58, XP002378487 DOI: http://dx.doi.org/10.1251/bpo4 | - BECERRA M et al., "Micro-scale purification of beta-galactosidase from Kluyveromyces lactis reveals that dimeric and tetrameric forms are active", Biotechnol. Techniques, (19980300), vol. 12, no. 3, pages 253 - 256, XP002378514 DOI: http://dx.doi.org/10.1023/A:1008885827560 | - DA SILVA M E et al., "Purification of microbial Beta-galactosidase from Kluyveromyces fragilis by bioaffinity partitioning", Revista de Microbiologia, vol. 30, (19990000), pages 324 - 331, URL: http://www.scielo.br/pdf/rm/v30n4/06_99-45.pdf, XP055312209 | - MITTAL et al., "The effect of protease contamination in lactase on the flavour of lactose-hydrolyzed milks", Austr. J Dairy Technol., (19910500), vol. 46, no. 1, pages 46 - 48, XP000214450 | - WEIQUN et al., "Purification and characterization of beta- galactosidase from Kluyveromyces lactis", Chin. J Biotechnol., (19930000), vol. 9, no. 4, pages 348 - 354, XP003031057 | - JIEYAN et al., "Lactose hydrolysis of milks by Klyveromyces lactis lactase", Food & Fermentation Industries, (19910000), pages 354 - 360, XP055316113 | - COENEN et al., "Safety evaluation of a lactase enzyme prepara- tion derived from Kluyveromyces lactis", Food Chem. Toxicol., (20000800), vol. 38, pages 671 - 677, XP055316549 DOI: http://dx.doi.org/10.1016/S0278-6915(00)00053-3 | - HUSSEIN et al., "Reduction of lactose in milk by purification lactase produced by Kluyveromyces lactis", J Food Protection, (19880100), vol. 52, no. 1, pages 30 - 34, XP003028138 | - DE VRESE et al., "Probiotics-compensation for lactase insufficiency", Am J Clin Nutr, (20010000), vol. 73, pages 421S - 429S, XP000984968 | - Anonymous, "List of compounds", Sigma Biochemikalien organische verbindungen und diagnostika, (19960000), pages 492 - 493, XP055316554 | - PORTNOY et al., "Separation of Alternaria into protein and carbohydrate fractions with phenyl Sepharose", J. Allergy Clin Immunol., vol. 87, no. 4, (19910400), pages 789 - 793, URL: 10.1016/0091-6749(91)90124-7, XP055316563 DOI: http://dx.doi.org/10.1016/0091-6749(91)90124-7 |