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EP About this file: EP1419235

EP1419235 - KNOCK IN TRANSGENIC MAMMAL CONTAINING A NON-FUNCTIONAL N-TERMINUS OF KV BETA 1.1 SUBUNIT [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 18.12.2009 Database last updated on 19.07.2024
Most recent event Tooltip	18.12.2009	Application deemed to be withdrawn	published on 20.01.2010 [2010/03]
Applicant(s)	For all designated states Wyeth Five Giralda Farms Madison, NJ 07940-0874 / US
	[N/P]
Former [2004/21]	For all designated states Wyeth Five Giralda Farms Madison, New Jersey 07940-0874 / US
Inventor(s)	01 / KWAK, Seung, Poon 38C Chicopee Drive Princeton, NJ 08540 / US
	02 / RHODES, Kenneth, James 808 Atkinson Circle Hillsborough, NJ 08844 / US
	03 / MARQUIS, Karen, Lovell 269 Rock Run Road Yardley, PA 19067 / US
	04 / COMERY, Thomas, Anthony 219 Flowers Avenue Langhorne, PA 19047 / US
	05 / ASKEW, Roger 11 High Ridge Road Boxford, MA 01921 / US
	06 / BRANDT, Michael, Richard 16 Lenape Road Flemington, NJ 08822 / US
	07 / ROSENZWEIG-LIPSON, Sharon, Joy 25 Bosko Drive East Brunswick, NJ 08816 / US
	[2004/21]
Representative(s)	Denholm, Anna Marie, et al Wyeth Pharmaceuticals Huntercombe Lane South Taplow Maidenhead Berkshire SL6 0PH / GB
	[2009/26]
Former [2007/08]	Denholm, Anna Marie, et al Wyeth Pharmaceuticals Patents & Trade Marks Department Huntercombe Lane South Taplow, Maidenhead Berkshire SL6 0PH / GB
Former [2004/21]	Ingham, Stephen H. Wyeth Pharmaceuticals, Patents & Trade Marks Dept., Huntercombe Lane South, Taplow Maidenhead, Berks SL6 0PH / GB
Application number, filing date	02763360.1	25.07.2002
	[2004/21]
	WO2002US23790
Priority number, date	US20010308485P	27.07.2001 Original published format: US 308485 P
	US20010331140P	09.11.2001 Original published format: US 331140 P
	[2004/21]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO03012041
	Date:	13.02.2003
	Language:	EN
	[2003/07]
	Type:	A2 Application without search report
	No.:	EP1419235
	Date:	19.05.2004
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 13.02.2003 takes the place of the publication of the European patent application.
	[2004/21]
Search report(s)	International search report - published on:	US	12.02.2004
	(Supplementary) European search report - dispatched on:	EP	17.01.2008
Classification	IPC:	C07H21/04, C12N15/63, C12N5/00, C12N15/09, C12N15/00, A01K67/00	[2004/29]
	CPC:	C12N15/8509 (EP,US); A01K67/0275 (EP,US); A01K67/0276 (EP,US); C07K14/705 (EP,US); A01K2217/072 (EP,US); A01K2217/075 (EP,US); (+) A01K2227/105 (EP,US); A01K2267/03 (EP,US); A01K2267/0356 (EP,US); C07K2319/42 (EP,US); C12N2800/30 (EP,US); G01N2333/705 (EP,US); G01N2500/10 (EP,US) (-)
	Former IPC [2004/21]	C12N1/00
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, SK, TR [2004/21]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
	SI	Not yet paid
Title	German:	TRANSGENER KNOCK-IN-SÄUGER MIT NICHTFUNKTIONELLEM N-TERMINUS DER K V- BETA-1.1-UNTEREINHEIT	[2004/21]
	English:	KNOCK IN TRANSGENIC MAMMAL CONTAINING A NON-FUNCTIONAL N-TERMINUS OF KV BETA 1.1 SUBUNIT	[2004/21]
	French:	CHOC DANS UN ANIMAL TRANSGENIQUE CONTENANT UNE EXTREMITE N-TERMINALE NON FONCTIONNELLE D'UNE SOUS-UNITE KV BETA 1.1	[2004/21]
Entry into regional phase	20.02.2004	National basic fee paid
	20.02.2004	Search fee paid
	20.02.2004	Designation fee(s) paid
	20.02.2004	Examination fee paid
Examination procedure	20.02.2004	Examination requested [2004/21]
	17.03.2009	Despatch of a communication from the examining division (Time limit: M04)
	28.07.2009	Application deemed to be withdrawn, date of legal effect [2010/03]
	03.09.2009	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2010/03]
Fees paid	Renewal fee
	09.07.2004	Renewal fee patent year 03
	08.07.2005	Renewal fee patent year 04
	10.07.2006	Renewal fee patent year 05
	04.07.2007	Renewal fee patent year 06
	27.03.2008	Renewal fee patent year 07
	Penalty fee
	Additional fee for renewal fee
	31.07.2009	08 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A] - RETTIG J ET AL, "INACTIVATION PROPERTIES OF VOLTAGE-GATED K+ CHANNELS ALTERED BY PRESENCE OF BETA-SUBUNIT", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, (19940526), vol. 369, no. 6478, ISSN 0028-0836, pages 289 - 294, XP002036596 [A] 1-97 * page 291, column R, paragraph 2 * * figure 3f * DOI: http://dx.doi.org/10.1038/369289a0
		[A] - WISSMANN R ET AL, "NMR structure and functional characteristics of the hydrophilic N terminus of the potassium channel beta-subunit Kvbeta1.1.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 10 DEC 1999, (19991210), vol. 274, no. 50, ISSN 0021-9258, pages 35521 - 35525, XP002460738 [A] 1-97 * figures 1,2 * * page 35524, paragraph L * DOI: http://dx.doi.org/10.1074/jbc.274.50.35521
		[A] - BÄHRING R ET AL, "Coupling of voltage-dependent potassium channel inactivation and oxidoreductase active site of Kvbeta subunits.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 22 JUN 2001, (20010622), vol. 276, no. 25, ISSN 0021-9258, pages 22923 - 22929, XP002460739 [A] 1-97 * page 22928, paragraph L * DOI: http://dx.doi.org/10.1074/jbc.M100483200
		[PX] - KWAK S P ET AL, "Creation and characterization of Kvbeta1.1 knock-in mice lacking the N-terminus necessary for rapid inactivation", SOCIETY FOR NEUROSCIENCE ABSTRACTS, & 31ST ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; SAN DIEGO, CALIFORNIA, USA; NOVEMBER 10-15, 2001, (2001), vol. 27, no. 2, ISSN 0190-5295, page 2145, XP002460147 [PX] 1-97 * abstract *
		[PX] - COMERY T A ET AL, "Mice expressing an inactive Kvbeta1.1 subunit, but not Kvbeta1.1 knockout mice, display impaired contextual fear conditioning and different profiles on the elevated zero maze", SOCIETY FOR NEUROSCIENCE ABSTRACTS, & 31ST ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; SAN DIEGO, CALIFORNIA, USA; NOVEMBER 10-15, 2001, (2001), vol. 27, no. 2, ISSN 0190-5295, page 2145, XP002460148 [PX] 1-97 * abstract *
		[PX] - BRANDT M R ET AL, "Effects of knockout or inactive Kvbeta1.1 subunits on spatial learning and nociception in genically modified mice", SOCIETY FOR NEUROSCIENCE ABSTRACTS, & 31ST ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; SAN DIEGO, CALIFORNIA, USA; NOVEMBER 10-15, 2001, (2001), vol. 27, no. 2, ISSN 0190-5295, page 2146, XP002460149 [PX] 1-97 * abstract *
		[PX] - AIMOND FRANCK ET AL, "Modulation of voltage-gated K+ currents in mouse ventricular myocytes by KVbeta1 subunits", BIOPHYSICAL JOURNAL, & 46TH ANNUAL MEETING OF THE BIOPHYSICAL SOCIETY; SAN FRANCISCO, CALIFORNIA, USA; FEBRUARY 23-27, 2002, (200201), vol. 82, no. 1 Part 2, ISSN 0006-3495, page 26a, XP002460150 [PX] 1-97 * abstract *
		[T] - BRENNAN J A ET AL, "MICE EXPRESSING AN INACTIVE KVbeta1.1 SUBUNIT DISPLAY AN ANXIOLYTIC PHENOTYPE IN STRESS - INDUCED HYPERTHERMIA AND FOUR - PLATE MODELS.", SOCIETY FOR NEUROSCIENCE ABSTRACT VIEWER AND ITINERARY PLANNER, & 32ND ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; ORLANDO, FLORIDA, USA; NOVEMBER 02-07, 2002, (2002), vol. 2002, pages Abstract No. 398.12 URL - http://sf, XP002460146 [T] 1-97 * abstract *
	International search	[Y]WO0024871 (UNIV CALIFORNIA [US]);
		[YP]US6365370 (DUBIN ADRIENNE E [US], et al);
		[AE]US2003024001 (KWAK SEUNG P [US], et al);
		[Y] - PONHD O. ET AL., "Functional and molecular aspects of voltage-gated K+ channel beta subunits", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, (19990430), vol. 868, pages 344 - 355, XP001119013 DOI: http://dx.doi.org/10.1111/j.1749-6632.1999.tb11296.x

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