blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP1436310

EP1436310 - ANTISENSE MODULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 EXPRESSION [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  18.02.2005
Database last updated on 13.11.2024
Most recent event   Tooltip13.11.2009Change - representativepublished on 16.12.2009  [2009/51]
Applicant(s)For all designated states
Isis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
[N/P]
Former [2004/29]For all designated states
ISIS PHARMACEUTICALS, INC.
2292 Faraday Avenue
Carlsbad, CA 92008 / US
Inventor(s)01 / BENNETT, C., Frank
1347 Cassing Street
Carlsbad, CA 92008 / US
02 / WATT, Andrew, T.
1500 Shadowridge Drive Apartment 154
Vista, CA 92083 / US
 [2004/29]
Representative(s)Hallybone, Huw George, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2009/51]Hallybone, Huw George, et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Former [2004/29]Hallybone, Huw George, et al
Carpmaels and Ransford, 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date02763756.026.09.2002
[2004/29]
WO2002US30734
Priority number, dateUS2001096765528.09.2001         Original published format: US 967655
[2004/29]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03029266
Date:10.04.2003
Language:EN
[2003/15]
Type: A1 Application with search report 
No.:EP1436310
Date:14.07.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 10.04.2003 takes the place of the publication of the European patent application.
[2004/29]
Search report(s)International search report - published on:US10.04.2003
ClassificationIPC:C07H21/04, C07H21/02, A61K48/00, C12Q1/68, C12N15/85, C12N15/86, C12P19/34, C12N15/11
[2005/13]
CPC:
C12N15/1138 (EP,US); A61K38/00 (EP,US); C12N2310/315 (EP,US);
C12N2310/321 (EP,US); C12N2310/3341 (EP,US); C12N2310/341 (EP,US);
C12N2310/346 (EP,US); Y02P20/582 (EP,US) (-)
C-Set:
C12N2310/321, C12N2310/3525 (EP,US)
Former IPC [2004/29]C07H21/04, C07H21/02, A61K48/00, C12Q1/68, C12N15/85, C12N15/86, C12P19/34
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/29]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:ANTISENSE-MODULATION DES VASKULÄREN ENDOTHELWACHSTUMSFAKTOR REZEPTORS 2[2004/29]
English:ANTISENSE MODULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 EXPRESSION[2004/29]
French:MODULATION ANTISENS DE L'EXPRESSION DU RECEPTEUR 2 DU FACTEUR DE CROISSANCE DE L'ENDOTHELIUM VASCULAIRE[2004/29]
Entry into regional phase22.04.2004National basic fee paid 
22.04.2004Search fee paid 
22.04.2004Designation fee(s) paid 
22.04.2004Examination fee paid 
Examination procedure16.04.2003Request for preliminary examination filed
International Preliminary Examining Authority: US
22.04.2004Amendment by applicant (claims and/or description)
22.04.2004Examination requested  [2004/29]
09.02.2005Application withdrawn by applicant  [2005/14]
Fees paidRenewal fee
22.04.2004Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[Y]US5801154  (BARACCHINI EDGARDO [US], et al);
 [A]US6346398  (PAVCO PAMELA [US], et al);
 [X]  - PARRY ET AL., "Bioactivity of anti-angiogenic ribozymes targeting Flt-1 and KDR mRNA", NUCLEIC ACIDS RESEARCH, (199905), vol. 27, no. 13, pages 2569 - 2577, XP002971041

DOI:   http://dx.doi.org/10.1093/nar/27.13.2569
 [X]  - PAVCO ET AL., "Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors", CLINICAL CANCER RESEARCH, (200005), vol. 6, pages 2094 - 2103, XP002971042
 [X]  - HENDERSON ET AL., "The basic-helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (20010302), vol. 276, no. 9, pages 6169 - 6176, XP002971043

DOI:   http://dx.doi.org/10.1074/jbc.M008506200
 [X]  - BERNATCHEZ ET AL., "Vascular endothelial growth factor effect on endothelial cell proliferation, migration and platelet-activating factor synthesis is Flk-1-dependent", JOURNAL OF BIOLOGICAL CHEMISTRY, (19991022), vol. 274, no. 43, pages 31047 - 31054, XP002971044

DOI:   http://dx.doi.org/10.1074/jbc.274.43.31047
 [X]  - BERARD ET AL., "Vascular endothelial growth factor confers a growth advantage in vitro and in vivo to stromal cells cultured from neonatal hemangiomas", AMERICAN JOURNAL OF PATHOLOGY, (199704), vol. 150, no. 4, pages 1315 - 1326, XP002971045
 [Y]  - MILNER ET AL., "Selecting effective antisense reagents on combinatorial oligonucleotide arrays", NATURE BIOTECHNOLOGY, (199706), vol. 15, pages 537 - 541, XP002971046

DOI:   http://dx.doi.org/10.1038/nbt0697-537
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.