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Extract from the Register of European Patents

EP About this file: EP1420794

EP1420794 - PROSTAGLANDIN ANALOGS AS CHLORIDE CHANNEL OPENERS [Right-click to bookmark this link]
Former [2004/22]PROSTAGLANDIN ANALOGS AS CHLORIDE CHANNEL OPENER
[2017/23]
StatusNo opposition filed within time limit
Status updated on  02.11.2018
Database last updated on 07.10.2024
FormerThe patent has been granted
Status updated on  24.11.2017
FormerGrant of patent is intended
Status updated on  05.07.2017
Most recent event   Tooltip19.06.2020Lapse of the patent in a contracting state
New state(s): IE		published on 22.07.2020  [2020/30]
Applicant(s)For all designated states
Sucampo AG
Baarerstrasse 22
6300 Zug / CH
[2017/52]
Former [2004/22]For all designated states
Sucampo AG
Graben 5
6300 Zug / CH
Inventor(s)01 / UENO, Ryuji
11025 Stanmore Drive, Potomac
Montgomery, MD 20854 / US
02 / CUPPOLETTI, John
56 Bayham Drive
Cincinnati, OH 45218 / US
 [2004/22]
Representative(s)Beckmann, Claus, et al
Kraus & Weisert
Patentanwälte PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
[2014/41]
Former [2014/38]Adam, Holger, et al
Kraus & Weisert
Patentanwälte PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
Former [2004/22]Albrecht, Thomas, Dr.
Kraus & Weisert Patent- und Rechtsanwälte Thomas-Wimmer-Ring 15
80539 München / DE
Application number, filing date02767866.329.08.2002
[2004/22]
WO2002JP08705
Priority number, dateUS20010315917P31.08.2001         Original published format: US 315917 P
US20020372104P15.04.2002         Original published format: US 372104 P
[2004/22]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03030912
Date:17.04.2003
Language:EN
[2003/16]
Type: A1 Application with search report 
No.:EP1420794
Date:26.05.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 17.04.2003 takes the place of the publication of the European patent application.
[2004/22]
Type: B1 Patent specification 
No.:EP1420794
Date:27.12.2017
Language:EN
[2017/52]
Search report(s)International search report - published on:EP17.04.2003
ClassificationIPC:A61K31/557, C07C405/00
[2004/22]
CPC:
C07C405/00 (EP,US); A61K31/557 (EP,US); A61P1/00 (EP);
A61P11/00 (EP); A61P11/06 (EP); A61P11/08 (EP);
A61P13/12 (EP); A61P21/02 (EP); A61P25/00 (EP);
A61P25/08 (EP); A61P25/20 (EP); A61P25/22 (EP);
A61P25/28 (EP); A61P3/14 (EP); A61P43/00 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2017/52]
Former [2004/22]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE,  SK,  TR 
TitleGerman:PROSTAGLANDIN-ANALOGA ALS CHLORIDKANALÖFFNER[2004/22]
English:PROSTAGLANDIN ANALOGS AS CHLORIDE CHANNEL OPENERS[2017/23]
French:ANALOGUES DE LA PROSTAGLANDINE EN TANT QU'AGENTS D'OUVERTURE DES CANAUX DE CHLORURE[2017/23]
Former [2004/22]PROSTAGLANDIN ANALOGS AS CHLORIDE CHANNEL OPENER
Former [2004/22]ANALOGUES A LA PROSTAGLANDINE EN TANT QU'AGENTS D'OUVERTURE DES CANAUX DE CHLORURE
Entry into regional phase18.03.2004National basic fee paid 
18.03.2004Designation fee(s) paid 
18.03.2004Examination fee paid 
Examination procedure24.04.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
18.03.2004Examination requested  [2004/22]
19.05.2004Amendment by applicant (claims and/or description)
27.06.2006Despatch of a communication from the examining division (Time limit: M06)
05.01.2007Reply to a communication from the examining division
22.09.2008Despatch of a communication from the examining division (Time limit: M06)
16.03.2009Reply to a communication from the examining division
08.03.2011Despatch of a communication from the examining division (Time limit: M06)
04.08.2011Reply to a communication from the examining division
06.07.2017Communication of intention to grant the patent
15.11.2017Fee for grant paid
15.11.2017Fee for publishing/printing paid
15.11.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  27.06.2006
Opposition(s)28.09.2018No opposition filed within time limit [2018/49]
Fees paidRenewal fee
12.08.2004Renewal fee patent year 03
12.08.2005Renewal fee patent year 04
14.08.2006Renewal fee patent year 05
14.08.2007Renewal fee patent year 06
14.08.2008Renewal fee patent year 07
12.08.2009Renewal fee patent year 08
13.08.2010Renewal fee patent year 09
04.08.2011Renewal fee patent year 10
07.08.2012Renewal fee patent year 11
09.08.2013Renewal fee patent year 12
19.08.2014Renewal fee patent year 13
21.07.2015Renewal fee patent year 14
14.07.2016Renewal fee patent year 15
17.08.2017Renewal fee patent year 16
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
MC27.12.2017
NL27.12.2017
PT27.12.2017
SE27.12.2017
SK27.12.2017
TR27.12.2017
BG27.03.2018
GR28.03.2018
GB29.08.2018
IE29.08.2018
LU29.08.2018
BE31.08.2018
CH31.08.2018
FR31.08.2018
LI31.08.2018
[2020/30]
Former [2020/28]AT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
MC27.12.2017
NL27.12.2017
PT27.12.2017
SE27.12.2017
SK27.12.2017
TR27.12.2017
BG27.03.2018
GR28.03.2018
GB29.08.2018
LU29.08.2018
BE31.08.2018
CH31.08.2018
FR31.08.2018
LI31.08.2018
Former [2020/16]AT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
MC27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
TR27.12.2017
BG27.03.2018
GR28.03.2018
GB29.08.2018
LU29.08.2018
BE31.08.2018
CH31.08.2018
FR31.08.2018
LI31.08.2018
Former [2019/47]AT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
MC27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
GB29.08.2018
LU29.08.2018
BE31.08.2018
CH31.08.2018
FR31.08.2018
LI31.08.2018
Former [2019/38]AT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
MC27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
LU29.08.2018
BE31.08.2018
CH31.08.2018
FR31.08.2018
LI31.08.2018
Former [2019/21]AT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
MC27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
LU29.08.2018
CH31.08.2018
LI31.08.2018
Former [2019/15]AT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
MC27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
Former [2018/51]AT27.12.2017
CY27.12.2017
CZ27.12.2017
DK27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
Former [2018/40]AT27.12.2017
CY27.12.2017
CZ27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
IT27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
Former [2018/38]AT27.12.2017
CY27.12.2017
CZ27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
Former [2018/37]CY27.12.2017
CZ27.12.2017
EE27.12.2017
ES27.12.2017
FI27.12.2017
NL27.12.2017
SE27.12.2017
SK27.12.2017
BG27.03.2018
GR28.03.2018
Former [2018/34]FI27.12.2017
NL27.12.2017
SE27.12.2017
BG27.03.2018
GR28.03.2018
Former [2018/24]FI27.12.2017
SE27.12.2017
BG27.03.2018
GR28.03.2018
Former [2018/22]FI27.12.2017
Cited inInternational search[E]WO02089812  (SUCAMPO AG [CH], et al) [E] 2,4-13,16-28,32,34-43,45 * page 19, line 14 - line 24 * * claims 1-39 *;
 [XP]WO0176593  (R TECH UENO LTD [JP]) [XP] 16-19,21,23,25,27,28,46 * claims 1-73 * * page 16, line 16 - line 18 *;
 [XP]WO0170233  (R TECH UENO LTD [JP]) [XP] 16-19,21,23,25,27,28,46 * claims 1-57 * * page 17, line 8 - line 10 *;
 [XY]EP0979651  (R TECH UENO LTD [JP]) [X] 16-19,21,23,25,27,28,46 * claims 1-58 * * page 5, paragraph 38 * [Y] 2,4-13,32,34-43;
 [X]EP0978284  (R TECH UENO LTD [JP]) [X] 16-19,21,23,25,27,28,46 * claims 1-33 * * page 5, paragraph 40 *;
 [X]EP0690049  (R TECH UENO LTD [JP]) [X] 16-19,21,23,25,27 * claims 1-28 *;
 [X]EP0430552  (UENO SEIYAKU OYO KENKYUJO KK [JP]) [X] 2,4-13,16-19,21,23,25,27,28,32,34,36,38,40,42,43,46 * page 3, lines 1,2 * * page 4, line 20 - page 5, line 42 * * claims 1-8 *;
 [X]EP1082961  (TAISHO PHARMA CO LTD [JP], et al) [X] 2,4,16-19,32,34 * the whole document *;
 [X]EP0310305  (UENO SEIYAKU OYO KENKYUJO KK [JP]) [X] 16-19,21,23,25,27 * the whole document *;
 [X]GB2075015  (ONO PHARMACEUTICAL CO) [X] 16-19,28 * the whole document *;
 [Y]US6015828  (CUPPOLETTI JOHN [US]) [Y] 2,3,32,33 * claims 1-17 *;
 [Y]  - DAJANI E Z ET AL, "EFFECTS OF E PROSTAGLANDINS, DIPHENOXYLATE AND MORPHINE ON INTESTINAL MOTILITY IN VIVO", EUROPEAN JOURNAL OF PHARMACOLOGY, AMSTERDAM, NL, (197511), vol. 1, no. 34, ISSN 0014-2999, pages 105 - 113, XP001095316 [Y] 2,4-13,32,34-43 * the whole document *

DOI:   http://dx.doi.org/10.1016/0014-2999(75)90230-7
 [XD]  - DEACHAPUNYA C ET AL, "Regulation of chloride secretion across porcine endometrial epithelial cells by prostaglandin E2.", MEDLINE, (19980401), Database accession no. NLM9490813, XP002227298 [XD] 1,31 * abstract *
    [ ] - THE JOURNAL OF PHYSIOLOGY. ENGLAND 1 APR 1998, (19980401), vol. 508 ( Pt 1), ISSN 0022-3751, pages 31 - 47
 [XD]  - H. SAKAI ET AL, "A Gastric Housekeeping Cl- Channel Activated via Prostaglandin EP3 Receptor-mediated Ca2+/Nitric Oxide/cGMP Pathway", JOURNAL OF BIOLOGICAL CHEMISTRY, (19950811), vol. 270, no. 32, pages 18781 - 18785, XP002227295 [XD] 1,31 * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.270.32.18781
 [XY]  - KA. A. YURKO-MAURO ET AL, "Prostaglandin F2alpha stimulates CFTR activity by PKA- and PKC-dependent phosphorylation", AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, (1998), vol. 275, pages C653 - C660, XP002227296 [X] 1,31 * abstract * [Y] 2,3,32,33
 [XDY]  - L.N. CHAN ET AL, "Activation of an Adenosine 3' ,5'-Cyclic Monophosphate-Dependent CL- Conductance in Response to Neurohormonal Stimuli in Mouse Endometrial Epithelial Cells: The Role of Cystic Fibrosis Transmembrane Conductance Regulator", BIOLOGY OF REPRODUCTION, (1999), vol. 60, no. 2, pages 374 - 380, XP002227297 [XD] 1,31 * abstract * [Y] 2,3,32,33

DOI:   http://dx.doi.org/10.1095/biolreprod60.2.374
 [Y]  - DALEMANS W ET AL, "ALTERED CHLORIDE ION CHANNEL KINETICS ASSOCIATED WITH THE AF508 CYSTIC FIBROSIS MUTATION", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, (19911219), vol. 354, ISSN 0028-0836, pages 526 - 528, XP000611996 [Y] 2,3,32,33 * abstract *

DOI:   http://dx.doi.org/10.1038/354526a0
ExaminationEP0978284
by applicantWO02089812
 WO0176593
 WO0170233
 EP0978284
 EP0430552
 EP0310305
 US6015828
 US5073569
 US5166174
 US5221763
 US5212324
 US5739161
 US6242485
    - BIOLOGY OF REPRODUCTION, (1999), vol. 60, no. 2
    - J. PHYSIOL., (1998), vol. 508, pages 31 - 47
    - J. BIOL. CHEM., (1995), vol. 270, no. 32, pages 18781 - 5
    - AM. J. PHYSIOL., vol. 199H, no. Z/B, pages CB5J - 60
    - BIOL. REPROD., (1999), vol. 60, no. 2, pages 374 - 80
    - NATURE, (1991), vol. 354, no. 6354, pages 526 - 8
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.