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Extract from the Register of European Patents

EP About this file: EP1430133

EP1430133 - A SOLUBLE TOLL-LIKE RECEPTOR [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  14.03.2014
Database last updated on 31.08.2024
Most recent event   Tooltip11.04.2014Lapse of the patent in a contracting state
New state(s): CH, LI
published on 14.05.2014  [2014/20]
Applicant(s)For all designated states
SOCIETE DES PRODUITS NESTLE S.A.
Case postale 353
1800 Vevey / CH
[2007/17]
Former [2004/26]For all designated states
SOCIETE DES PRODUITS NESTLE S.A.
Case postale 353
1800 Vevey / CH
Inventor(s)01 / SCHIFFRIN, Eduardo
17, chemin de Riant-Mont
CH-1023 Crissier / CH
02 / AFFOLTER, Michael
8, chemin de la Séchaude
CH-1073 Savigny / CH
03 / LABETA, Mario O.
70 Dartington Drive
Cardiff, CF 23 8SA / GB
 [2004/26]
Representative(s)Caen, Thierry Alain
Cabinet Santarelli
14, avenue de la Grande Armée
75017 Paris / FR
[N/P]
Former [2011/03]Caen, Thierry Alain
Cabinet Santarelli 14, avenue de la Grande Armée
75017 Paris / FR
Former [2011/02]Caen, Thierry Alain, et al
Cabinet Santarelli 14, avenue de la Grande Armée
75017 Paris / FR
Former [2009/43]Corticchiato, Olivier, et al
Nestec S.A. Avenue Nestlé 55
1800 Vevey / CH
Former [2006/50]Dixon, Sarah, et al
Nestec S.A. IP Group/Patent Avenue Nestlé 55
1800 Vevey / CH
Former [2005/08]Becker Kurig Straus
Patentanwälte Bavariastrasse 7
80336 München / DE
Former [2004/26]Schneiter, Sorin
Avenue Nestlé 55
1800 Vevey / CH
Application number, filing date02777127.813.09.2002
[2004/26]
WO2002EP10410
Priority number, dateEP2001012169817.09.2001         Original published format: EP 01121698
[2004/26]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03025015
Date:27.03.2003
Language:EN
[2003/13]
Type: A2 Application without search report 
No.:EP1430133
Date:23.06.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 27.03.2003 takes the place of the publication of the European patent application.
[2004/26]
Type: B1 Patent specification 
No.:EP1430133
Date:25.04.2007
Language:EN
[2007/17]
Search report(s)International search report - published on:EP28.08.2003
ClassificationIPC:C12N15/12, C07K14/705, C07K16/28, C12N5/10, A61K38/17, // A61P1/00, A61P11/00, A61P17/00
[2004/26]
CPC:
C07K14/705 (EP,US); A61P1/00 (EP); A61P11/00 (EP);
A61P17/00 (EP); A61P29/00 (EP); A61P37/02 (EP);
A61P37/08 (EP); A61K38/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/26]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:EIN LÖSLICHER TOLL-ÄHNLICHER REZEPTOR[2004/26]
English:A SOLUBLE TOLL-LIKE RECEPTOR[2004/26]
French:MOLECULE REGULATRICE DU RECEPTEUR TOLL SOLUBLE[2004/26]
Entry into regional phase19.04.2004National basic fee paid 
19.04.2004Designation fee(s) paid 
19.04.2004Examination fee paid 
Examination procedure11.04.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
19.04.2004Examination requested  [2004/26]
23.08.2004Despatch of a communication from the examining division (Time limit: M06)
09.02.2005Reply to a communication from the examining division
08.07.2005Despatch of a communication from the examining division (Time limit: M08)
28.02.2006Reply to a communication from the examining division
09.03.2006Despatch of a communication from the examining division (Time limit: M04)
19.07.2006Reply to a communication from the examining division
13.10.2006Communication of intention to grant the patent
23.02.2007Fee for grant paid
23.02.2007Fee for publishing/printing paid
Opposition(s)Opponent(s)01  25.01.2008  09.04.2008  ADMISSIBLE
N.V. Nutricia
Eerste Stationsstraat 186
2712 HM Zoetermeer / NL
Opponent's representative
Nederlandsch Octrooibureau
P.O. Box 29720
2502 LS The Hague / NL
 [N/P]
Former [2013/32]
Opponent(s)01  25.01.2008  09.04.2008  ADMISSIBLE
N.V. Nutricia
Eerste Stationsstraat 186
2712 HM Zoetermeer / NL
Opponent's representative
Nederlandsch Octrooibureau
P.O. Box 29720
2502 LS The Hague / NL
Former [2011/03]
Opponent(s)01  25.01.2008  09.04.2008  ADMISSIBLE
N.V. Nutricia
Eerste Stationsstraat 186
2712 HM Zoetermeer / NL
Opponent's representative
Meekel, Arthur Augustinus P.
Nederlandsch Octrooibureau P.O. Box 29720
2502 LS Den Haag / NL
Former [2010/52]
Opponent(s)01  25.01.2008  09.04.2008  ADMISSIBLE
N.V. Nutricia
Eerste Stationsstraat 186
2712 HM Zoetermeer / NL
Opponent's representative
Caen, Thierry Alain
Santarelli, 14 Avenue de la Grande Armée
75822 Paris Cedex 17 / FR
Former [2008/10]
Opponent(s)01  25.01.2008   
N.V. Nutricia
Eerste Stationsstraat 186
2712 HM Zoetermeer / NL
Opponent's representative
Meekel, Arthur Augustinus P.
Nederlandsch Octrooibureau P.O. Box 29720
2502 LS Den Haag / NL
07.05.2008Invitation to proprietor to file observations on the notice of opposition
09.09.2008Reply of patent proprietor to notice(s) of opposition
26.01.2010Date of oral proceedings
26.03.2010Despatch of interlocutory decision in opposition
26.03.2010Despatch of minutes of oral proceedings
16.01.2014Legal effect of revocation of patent [ N /P ]
16.01.2014Legal effect of revocation of patent [2014/16]
12.02.2014Despatch of communication that the patent will be revoked
Appeal following opposition27.05.2010Appeal received No.  T1222/10
22.07.2010Statement of grounds filed
16.01.2014Result of appeal procedure: revocation of the patent
16.01.2014Date of oral proceedings
23.01.2014Minutes of the oral proceedings despatched
Fees paidRenewal fee
14.09.2004Renewal fee patent year 03
14.09.2005Renewal fee patent year 04
11.09.2006Renewal fee patent year 05
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCH25.04.2007
CY25.04.2007
EE25.04.2007
LI25.04.2007
SK25.04.2007
BG25.07.2007
LU13.09.2007
MC30.09.2007
[2014/20]
Former [2009/38]CY25.04.2007
EE25.04.2007
SK25.04.2007
BG25.07.2007
LU13.09.2007
MC30.09.2007
Former [2009/34]CY25.04.2007
EE25.04.2007
SK25.04.2007
BG25.07.2007
MC30.09.2007
Former [2009/10]EE25.04.2007
SK25.04.2007
BG25.07.2007
MC30.09.2007
Former [2008/22]SK25.04.2007
BG25.07.2007
MC30.09.2007
Former [2008/13]SK25.04.2007
BG25.07.2007
Former [2008/09]BG25.07.2007
Cited inInternational search[X]EP0864585  (HAYASHIBARA BIOCHEM LAB [JP]) [X] 1,2,8,10-27 * the whole document *;
 [X]WO9937772  (IMMUNEX CORP [US], et al) [X] 1,2,8,10-27 * the whole document *;
 [X]  - FLO T H ET AL, "Detection of soluble TLR2 in human serum samples by ELISA.", JOURNAL OF ENDOTOXIN RESEARCH, 6th Conference of the International Endotoxin Society;Paris, France; August 24-27, 2000, (2000), vol. 6, no. 2, ISSN 0968-0519, page 106, XP001052916 [X] 1-7,10 * the whole document *
 [X]  - FILIPP DOMINIK ET AL, "Soluble CD14 enriched in colostrum and milk induces B cell growth and differentiation.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, January 16, 2001, (20010116), vol. 98, no. 2, ISSN 0027-8424, pages 603 - 608, XP002187481 [X] 1-6,8-27 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.98.2.603
 [X]  - LABETA MARIO O ET AL, "Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14.", JOURNAL OF EXPERIMENTAL MEDICINE, (20000515), vol. 191, no. 10, ISSN 0022-1007, pages 1807 - 1812, XP002187480 [X] 1-6,8-12,14-19,21-25,27 * the whole document *

DOI:   http://dx.doi.org/10.1084/jem.191.10.1807
 [X]  - DU ET AL., "Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor", BLOOD CELLS, MOLECULES AND DISEASES, (19991115), vol. 25, no. 6, pages 328 - 338, XP002183507 [X] 1-6,10-27 * the whole document *

DOI:   http://dx.doi.org/10.1006/bcmd.1999.0262
 [X]  - XU YINGWU ET AL, "Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.", NATURE (LONDON), (2000), vol. 408, no. 6808, ISSN 0028-0836, pages 111 - 115, XP002183508 [X] 1,2,7,8,11-13 * the whole document *

DOI:   http://dx.doi.org/10.1038/35047056
 [X]  - PRUITT JEFFREY H ET AL, "Increased soluble interleukin-1 type II receptor concentrations in postoperative patients and in patients with sepsis syndrome.", BLOOD, (1996), vol. 87, no. 8, ISSN 0006-4971, pages 3282 - 3288, XP001041460 [X] 1,2,8,10 * the whole document *
 [A]  - O'NEILL L A J ET AL, "The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense", IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, (200005), vol. 21, no. 5, ISSN 0167-5699, pages 206 - 209, XP004198146 [A] 14-27 * page 209, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1016/S0167-5699(00)01611-X
 [A]  - MANTOVANI A ET AL, "Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines", TRENDS IN IMMUNOLOGY, ELSEVIER, CAMBRIDGE, GB, (20010601), vol. 22, no. 6, ISSN 1471-4906, pages 328 - 336, XP004249049 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/S1471-4906(01)01941-X
 [A]  - KOLB A F, "The prospects of modifying the antimicrobial properties of milk", BIOTECHNOLOGY ADVANCES, ELSEVIER PUBLISHING, BARKING, GB, (200107), vol. 19, no. 4, ISSN 0734-9750, pages 299 - 316, XP004274975 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/S0734-9750(01)00069-6
ExaminationWO9920756
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