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Extract from the Register of European Patents

EP About this file: EP1455824

EP1455824 - LYOPHILIZED PREPARATION CONTAINING ANTIBODIES TO THE EGF RECEPTOR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.06.2009
Database last updated on 03.05.2025
Most recent event   Tooltip29.10.2010Lapse of the patent in a contracting state
New state(s): GR		published on 01.12.2010  [2010/48]
Applicant(s)For all designated states
Merck Patent GmbH
Frankfurter Strasse 250
64293 Darmstadt / DE
[2008/32]
Former [2004/38]For all designated states
MERCK PATENT GmbH
Frankfurter Strasse 250
64293 Darmstadt / DE
Inventor(s)01 / MAHLER, Hanns-Christian
Buschungstrasse 54a
65205 Wiesbaden / DE
02 / ZOBEL, Hans-Peter
Bahnweg 5A
65439 Flörsheim / DE
03 / MÜLLER, Robert
Rhönring 131
64289 Darmstadt / DE
04 / BACHMANN, Christiane
Am Mattes 33
66773 Gladbach / DE
05 / HAAS, Udo
Trinkbornstrasse 30
64293 Darmstadt / DE
06 / KRÜGER, Ludwig
Ruhlandstrasse 75
63741 Aschaffenburg / DE
07 / MARTINI-MARR, Ulrike
Mühleweg 9
D- 79591 Eimeldingen / DE
 [2004/43]
Former [2004/38]01 / MAHLER, Hanns-Christian
Buschungstrasse 54a
65205 Wiesbaden / DE
02 / ZOBEL, Hans-Peter
Bahnweg 5A
65439 Flörsheim / DE
03 / MÜLLER, Robert
Rhönring 131
64289 Darmstadt / DE
04 / BACHMANN, Christiane
Am Mattes 33
66773 Gladbach / DE
05 / HAAS, Udo
Trinkbornstrasse 30
64293 Darmstadt / DE
06 / KRÜGER, Ludwig
Ruhlandstrasse 75
63741 Aschaffenburg / DE
07 / MARTINI-MARR, Ulrike
Im Schöffenstuhl 8
64319 Pfungstadt / DE
Application number, filing date02792797.925.11.2002
[2004/38]
WO2002EP13223
Priority number, dateDE200116345921.12.2001         Original published format: DE 10163459
[2004/38]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report
No.:WO03053465
Date:03.07.2003
Language:DE
[2003/27]
Type: A2 Application without search report 
No.:EP1455824
Date:15.09.2004
Language:DE
The application published by WIPO in one of the EPO official languages on 03.07.2003 takes the place of the publication of the European patent application.
[2004/38]
Type: B1 Patent specification 
No.:EP1455824
Date:06.08.2008
Language:DE
[2008/32]
Search report(s)International search report - published on:EP04.12.2003
ClassificationIPC:A61K39/395, A61K47/18, A61K47/26, A61K47/34, A61P35/00
[2004/38]
CPC:
C07K16/2863 (EP,US); A61K39/395 (KR); A61K47/02 (EP,US);
A61K47/10 (EP,US); A61K47/12 (EP,US); A61K47/18 (KR);
A61K47/183 (EP,US); A61K47/26 (EP,KR,US); A61K9/0019 (EP,US);
A61K9/19 (EP,US); A61P35/00 (EP); A61K2039/505 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2008/32]
Former [2004/38]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE,  SK,  TR 
Extension statesALNot yet paid
LT06.05.2004
LV06.05.2004
MKNot yet paid
RO06.05.2004
SI06.05.2004
TitleGerman:LYOPHILISIERTE ZUBEREITUNG ENTHALTEND ANTIKÖRPER GEGEN DEN EGF-REZEPTOR[2004/38]
English:LYOPHILIZED PREPARATION CONTAINING ANTIBODIES TO THE EGF RECEPTOR[2004/38]
French:PREPARATION LYOPHILISEE RENFERMANT DES ANTICORPS LUTTANT CONTRE LE RECEPTEUR DU FACTEUR DE CROISSANCE EPIDERMIQUE EGF[2004/38]
Entry into regional phase06.05.2004National basic fee paid 
06.05.2004Designation fee(s) paid 
06.05.2004Examination fee paid 
Examination procedure26.06.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
06.05.2004Examination requested  [2004/38]
28.11.2006Despatch of a communication from the examining division (Time limit: M04)
09.03.2007Reply to a communication from the examining division
12.04.2007Despatch of a communication from the examining division (Time limit: M04)
25.07.2007Reply to a communication from the examining division
26.09.2007Despatch of a communication from the examining division (Time limit: M02)
21.11.2007Reply to a communication from the examining division
28.01.2008Communication of intention to grant the patent
25.04.2008Fee for grant paid
25.04.2008Fee for publishing/printing paid
Opposition(s)07.05.2009No opposition filed within time limit [2009/29]
Fees paidRenewal fee
12.11.2004Renewal fee patent year 03
14.11.2005Renewal fee patent year 04
14.11.2006Renewal fee patent year 05
15.11.2007Renewal fee patent year 06
31.03.2008Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY06.08.2008
CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
TR06.08.2008
BG06.11.2008
SE06.11.2008
GR07.11.2008
AT25.11.2008
LU25.11.2008
BE30.11.2008
MC30.11.2008
PT06.01.2009
[2010/48]
Former [2010/37]CY06.08.2008
CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
TR06.08.2008
BG06.11.2008
SE06.11.2008
AT25.11.2008
LU25.11.2008
BE30.11.2008
MC30.11.2008
PT06.01.2009
Former [2010/34]CY06.08.2008
CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
SE06.11.2008
AT25.11.2008
LU25.11.2008
BE30.11.2008
MC30.11.2008
PT06.01.2009
Former [2010/32]CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
SE06.11.2008
AT25.11.2008
LU25.11.2008
BE30.11.2008
MC30.11.2008
PT06.01.2009
Former [2010/09]CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
SE06.11.2008
AT25.11.2008
BE30.11.2008
MC30.11.2008
PT06.01.2009
Former [2010/08]CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
AT25.11.2008
BE30.11.2008
MC30.11.2008
PT06.01.2009
Former [2009/43]CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
BE30.11.2008
MC30.11.2008
PT06.01.2009
Former [2009/36]CZ06.08.2008
DK06.08.2008
EE06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
MC30.11.2008
PT06.01.2009
Former [2009/29]CZ06.08.2008
DK06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
MC30.11.2008
PT06.01.2009
Former [2009/25]CZ06.08.2008
DK06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
PT06.01.2009
Former [2009/24]CZ06.08.2008
DK06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
SK06.08.2008
BG06.11.2008
Former [2009/23]DK06.08.2008
FI06.08.2008
IE06.08.2008
NL06.08.2008
BG06.11.2008
Former [2009/20]DK06.08.2008
FI06.08.2008
NL06.08.2008
Former [2009/12]FI06.08.2008
NL06.08.2008
Cited inInternational search[DY]WO9822136  (BOEHRINGER MANNHEIM GMBH [DE], et al) [DY] 1-15 * page 10, line 21 - line 30; claim - * * page 12, paragraph 1 *;
 [Y]  - A.A. MORALES MORALES ET AL., "Freeze-dried formulation for direct 99mTc-labeling ior-egf/r3 MAb: Additives, biodistribution, and stability.", NUCLEAR MEDICINE & BIOLOGY, (199908), vol. 26, no. 6, pages 717 - 723, XP002252112 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0969-8051(99)00038-4
 [Y]  - J. BASELGA, "The EGFR as a target for anticancer therapy-focus on cetuximab", EUROPEAN JOURNAL OF CANCER, PERGAMON PRESS, OXFORD, GB, (200109), vol. 37, no. Suppl. 4, ISSN 0959-8049, pages S16 - S22, XP004307911 [Y] 1-15 * Seite S16, Zusammenfassung *

DOI:   http://dx.doi.org/10.1016/S0959-8049(01)00233-7
 [DY]  - H. BIER ET AL., "Anti-(epidermal growth factor) receptor monoclonal antibodies for the induction of antibody-dependent cell-mediated cytotoxicity against squamous cell carcinoma lines of the head and neck.", CANCER IMMUNOLOGY IMMUNOTHERAPY, (199805), vol. 46, no. 3, pages 167 - 173, XP002252113 [DY] 1-15 * Seite 167, Zusammenfassung *

DOI:   http://dx.doi.org/10.1007/s002620050475
Examination   - LAI M.C.; TOPP E.M., "Solid-State Chemical Stability of Proteins and Peptides", JOURNAL OF PHARMACEUTICAL SCIENCES, (199905), vol. 88, no. 5, pages 489 - 500
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.