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Extract from the Register of European Patents

EP About this file: EP1444890

EP1444890 - RS1 deficient transgenic animal and uses thereof [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.11.2009
Database last updated on 19.10.2024
Most recent event   Tooltip07.10.2011Lapse of the patent in a contracting state
New state(s): CY, TR		published on 09.11.2011  [2011/45]
Applicant(s)For all designated states
Koepsell, Hermann
Anatomisches Institut, Koellikerstrasse 6
97070 Würzburg / DE
[2009/02]
Former [2004/33]For all designated states
Koepsell, Hermann
Anatomisches Institut, Koellikerstrasse 6
97070 Würzburg / DE
Inventor(s)01 / Koepsell, Hermann
Inst. für Anatomie u. Zellbiologie Koellikerstr. 6
97070 Würzburg / DE
02 / Lang, Florian
Physiologisches Institut Gmelinstr. 5
72076 Tübingen / DE
03 / Osswald, Christina
Unterer Torweinberg, 10
97084 Würzburg / DE
 [2004/33]
Representative(s)Patentanwälte Ruff, Wilhelm, Beier, Dauster & Partner mbB
Kronenstrasse 30
70174 Stuttgart / DE
[N/P]
Former [2004/33]Patentanwälte Ruff, Wilhelm, Beier, Dauster & Partner
Kronenstrasse 30
70174 Stuttgart / DE
Application number, filing date03002465.705.02.2003
[2004/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1444890
Date:11.08.2004
Language:EN
[2004/33]
Type: B1 Patent specification 
No.:EP1444890
Date:07.01.2009
Language:EN
[2009/02]
Search report(s)(Supplementary) European search report - dispatched on:EP22.08.2003
ClassificationIPC:A01K67/027, C07K14/47, G01N33/50, A61K38/17, A61K48/00, G01N33/53, C12Q1/68
[2004/33]
CPC:
C12N15/8509 (EP,US); A01K67/0276 (EP,US); C07K14/4702 (EP,US);
C12Q1/6883 (EP,US); A01K2217/075 (EP,US); A01K2227/105 (EP,US);
A01K2267/03 (EP,US); A01K2267/0362 (EP,US); A61K38/00 (EP,US);
A61K48/00 (EP,US); C12Q2600/156 (EP,US); C12Q2600/158 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SI,   SK,   TR [2004/33]
TitleGerman:RS1 defizientes transgenes Tier und dessen Verwendungen[2007/48]
English:RS1 deficient transgenic animal and uses thereof[2004/33]
French:Animal transgénique présentant une déficience en RS1 et ses utilisations[2008/26]
Former [2004/33]RS1 defiziertes transgenes Tier und dessen Verwendungen
Former [2004/33]Animal transgénique présentant une déficience en RS1 et son utilisation
Examination procedure03.02.2005Examination requested  [2005/13]
08.11.2005Despatch of a communication from the examining division (Time limit: M06)
16.05.2006Reply to a communication from the examining division
04.06.2007Despatch of a communication from the examining division (Time limit: M04)
05.10.2007Reply to a communication from the examining division
04.02.2008Despatch of a communication from the examining division (Time limit: M02)
11.04.2008Reply to a communication from the examining division
28.07.2008Communication of intention to grant the patent
28.10.2008Fee for grant paid
28.10.2008Fee for publishing/printing paid
Opposition(s)08.10.2009No opposition filed within time limit [2009/51]
Fees paidRenewal fee
25.02.2005Renewal fee patent year 03
27.02.2006Renewal fee patent year 04
15.02.2007Renewal fee patent year 05
26.02.2008Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT07.01.2009
BE07.01.2009
CY07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
IT07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
TR07.01.2009
IE05.02.2009
LU05.02.2009
MC28.02.2009
BG07.04.2009
SE07.04.2009
GR08.04.2009
ES18.04.2009
PT08.06.2009
HU08.07.2009
[2011/44]
Former [2011/31]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
IT07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
IE05.02.2009
LU05.02.2009
MC28.02.2009
BG07.04.2009
SE07.04.2009
GR08.04.2009
ES18.04.2009
PT08.06.2009
HU08.07.2009
Former [2011/21]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
IT07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
IE05.02.2009
LU05.02.2009
MC28.02.2009
BG07.04.2009
SE07.04.2009
GR08.04.2009
ES18.04.2009
PT08.06.2009
Former [2011/14]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
IT07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
IE05.02.2009
MC28.02.2009
BG07.04.2009
SE07.04.2009
GR08.04.2009
ES18.04.2009
PT08.06.2009
Former [2010/48]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
IE05.02.2009
MC28.02.2009
BG07.04.2009
SE07.04.2009
GR08.04.2009
ES18.04.2009
PT08.06.2009
Former [2010/08]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
IE05.02.2009
MC28.02.2009
BG07.04.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2010/07]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
IE05.02.2009
MC28.02.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/50]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
SK07.01.2009
MC28.02.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/49]AT07.01.2009
BE07.01.2009
CZ07.01.2009
DK07.01.2009
EE07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
MC28.02.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/46]AT07.01.2009
BE07.01.2009
DK07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
MC28.02.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/43]AT07.01.2009
BE07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
MC28.02.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/42]AT07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
MC28.02.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/40]AT07.01.2009
FI07.01.2009
NL07.01.2009
SI07.01.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/38]FI07.01.2009
NL07.01.2009
SI07.01.2009
SE07.04.2009
ES18.04.2009
PT08.06.2009
Former [2009/34]NL07.01.2009
SI07.01.2009
ES18.04.2009
Former [2009/25]NL07.01.2009
SI07.01.2009
Documents cited:Search[X]DE10006887  (KOEPSELL HERMANN [DE]) [X] 17 * examples 1,7; claims 3,4,9 *;
 [X]  - KORN THOMAS ET AL, "The plasma membrane-associated protein RS1 decreases transcription of the transporter SGLT1 in confluent LLC-PK1 cells.", JOURNAL OF BIOLOGICAL CHEMISTRY, November 30, 2001, (20011130), vol. 276, no. 48, ISSN 0021-9258, pages 45330 - 45340, XP002250381 [X] 17 * page 45331, column 2 - page 45332, column 1; figures 1,2 *

DOI:   http://dx.doi.org/10.1074/jbc.M105975200
 [A]  - FUJITA Y ET AL, "Increased intestinal glucose absorption and postprandial hyperglycaemia at the early step of glucose intolerance in Otsuka Long-Evans Tokushima fatty rats.", DIABETOLOGIA, (199812), vol. 41, no. 12, ISSN 0012-186X, pages 1459 - 1466, XP002250382 [A] 1-9,12-17 * the whole document *

DOI:   http://dx.doi.org/10.1007/s001250051092
 [A]  - THOMSON A B R ET AL, "Adaptation of intestinal nutrient transport in health and disease: Part I.", DIGESTIVE DISEASES AND SCIENCES, (1997), vol. 42, no. 3, ISSN 0163-2116, pages 453 - 469, XP008020466 [A] 1-9,12-17 * page 456 - page 458 *

DOI:   http://dx.doi.org/10.1023/A:1018807120691
Examination   - BOHLEN H.G.; NASE G.P., "Obesity lowers hyperglycemic threshold for impaired in vivo endothelial nitric oxide function", AM. J. PHYSIOL. HEART CIRC PHYSIOL., (200207), vol. 283, pages H391 - H397
    - MASON J.C. ET AL, "Statin-induced expression of decay-accelerating factor protects vascular endothelium against complement mediated injury", CIRCULATION RESEARCH, (20021018), vol. 91, pages 696 - 703
    - TAKADA Y. ET AL, "Retinoschisin expression and localization in rodent and human pineal and consequences of mouse RS1 gene knockout", MOLECULAR VISION, (20060928), vol. 12, pages 1108 - 1116
    - WIDERA A. ET AL, "Mechanisms of TfR-mediated transcytosis and sorting in epithelial cells and applications toward drug delivery", ADVANCED DRUG DELIVERY REVIEWS, (2003), vol. 55, pages 1439 - 1466
    - BERNKOP-SCHNUERCH A.; PASTA M., "Intestinal peptide and protein delivery: novel bioadhesive drug-carrier matrix shielding from enzymatic attack", JOURNAL OF PHARMACEUTICAL SCIENCES, (199804), vol. 87, no. 4, pages 430 - 434
    - FRETZ ET AL, INT. J. PHARMACEUTICS, (2005), vol. 298, page 305
    - SNYDER; DOWDY, PHARM. RES., (2004), vol. 21, page 389
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.