EP1348760 - Production of inactive mutants or mutants with a low activity of an alkaline phosphatase and their expression in yeast [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 19.11.2010 Database last updated on 22.08.2024 | Most recent event Tooltip | 19.10.2012 | Lapse of the patent in a contracting state New state(s): TR | published on 21.11.2012 [2012/47] | Applicant(s) | For:DE
Roche Diagnostics GmbH Sandhofer Strasse 116 68305 Mannheim / DE | For:AT
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F. Hoffmann-La Roche AG Grenzacherstrasse 124 4070 Basel / CH | [N/P] |
Former [2010/02] | For:DE
Roche Diagnostics GmbH Sandhofer Strasse 116 68305 Mannheim / DE | ||
For:AT
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F.HOFFMANN-LA ROCHE AG Grenzacherstrasse 124 4070 Basel / CH | |||
Former [2003/40] | For:DE
Roche Diagnostics GmbH Sandhofer Strasse 116 68305 Mannheim / DE | ||
For:AT
BE
BG
CH
CY
CZ
DK
EE
ES
FI
FR
GB
GR
HU
IE
IT
LI
LU
MC
NL
PT
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SI
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TR
F.HOFFMANN-LA ROCHE AG Grenzacherstrasse 124 4070 Basel / CH | Inventor(s) | 01 /
Mueller, Rainer, Dr. An der Freiheit 54 82377 Penzberg / DE | 02 /
Thalhofer, Johann-Peter, Dr. Krottenkopfstrasse 9b 82362 Weilheim / DE | 03 /
Geipel, Frank, Dr. Nelkenstrasse 23 82377 Penzberg / DE | 04 /
Hoelke, Werner, Dr. An der Freiheit 73 82377 Penzberg / DE | 05 /
Kirschbaum, Thomas, Dr. Humboldtstrasse 3 81543 Muenchen / DE | [2003/40] | Representative(s) | Jung, Michael Roche Diagnostics GmbH Patentabteilung Sandhofer Strasse 116 68305 Mannheim / DE | [N/P] |
Former [2003/40] | Jung, Michael, Dr. Roche Diagnostics GmbH Patentabteilung 68298 Mannheim / DE | Application number, filing date | 03006426.5 | 21.03.2003 | [2003/40] | Priority number, date | DE2002113201 | 25.03.2002 Original published format: DE 10213201 | [2003/40] | Filing language | DE | Procedural language | DE | Publication | Type: | A2 Application without search report | No.: | EP1348760 | Date: | 01.10.2003 | Language: | DE | [2003/40] | Type: | A3 Search report | No.: | EP1348760 | Date: | 07.01.2004 | [2004/02] | Type: | B1 Patent specification | No.: | EP1348760 | Date: | 13.01.2010 | Language: | DE | [2010/02] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 20.11.2003 | Classification | IPC: | C12N9/16, C12N5/10 | [2003/40] | CPC: |
C12N9/16 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, RO, SE, SI, SK, TR [2003/40] | Title | German: | Erzeugung von schwach aktiven oder inaktiven Mutanten von Alkalischer Phosphatase und deren Expression in Hefe | [2003/40] | English: | Production of inactive mutants or mutants with a low activity of an alkaline phosphatase and their expression in yeast | [2003/40] | French: | Production de mutants d'une phosphatase alcaline inactifs ou ayant une activité reduite et leur expression dans la levure | [2003/40] | Examination procedure | 07.07.2004 | Examination requested [2004/37] | 10.08.2004 | Despatch of a communication from the examining division (Time limit: M06) | 11.01.2005 | Reply to a communication from the examining division | 19.03.2007 | Despatch of a communication from the examining division (Time limit: M04) | 14.07.2007 | Reply to a communication from the examining division | 11.05.2009 | Despatch of a communication from the examining division (Time limit: M04) | 27.05.2009 | Reply to a communication from the examining division | 07.08.2009 | Communication of intention to grant the patent | 27.11.2009 | Fee for grant paid | 27.11.2009 | Fee for publishing/printing paid | Opposition(s) | 14.10.2010 | No opposition filed within time limit [2010/51] | Fees paid | Renewal fee | 04.03.2005 | Renewal fee patent year 03 | 06.03.2006 | Renewal fee patent year 04 | 05.03.2007 | Renewal fee patent year 05 | 10.03.2008 | Renewal fee patent year 06 | 06.03.2009 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CY | 13.01.2010 | CZ | 13.01.2010 | DK | 13.01.2010 | EE | 13.01.2010 | FI | 13.01.2010 | IE | 13.01.2010 | RO | 13.01.2010 | SE | 13.01.2010 | SI | 13.01.2010 | SK | 13.01.2010 | TR | 13.01.2010 | AT | 21.03.2010 | LU | 21.03.2010 | BE | 31.03.2010 | CH | 31.03.2010 | LI | 31.03.2010 | MC | 31.03.2010 | BG | 13.04.2010 | GR | 14.04.2010 | PT | 13.05.2010 | HU | 14.07.2010 | [2012/47] |
Former [2012/43] | CY | 13.01.2010 | |
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EE | 13.01.2010 | ||
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IE | 13.01.2010 | ||
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SI | 13.01.2010 | ||
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AT | 21.03.2010 | ||
LU | 21.03.2010 | ||
BE | 31.03.2010 | ||
CH | 31.03.2010 | ||
LI | 31.03.2010 | ||
MC | 31.03.2010 | ||
BG | 13.04.2010 | ||
GR | 14.04.2010 | ||
PT | 13.05.2010 | ||
HU | 14.07.2010 | ||
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AT | 21.03.2010 | ||
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CH | 31.03.2010 | ||
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MC | 31.03.2010 | ||
BG | 13.04.2010 | ||
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PT | 13.05.2010 | ||
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AT | 21.03.2010 | ||
BE | 31.03.2010 | ||
CH | 31.03.2010 | ||
LI | 31.03.2010 | ||
MC | 31.03.2010 | ||
BG | 13.04.2010 | ||
GR | 14.04.2010 | ||
PT | 13.05.2010 | ||
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SI | 13.01.2010 | ||
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BE | 31.03.2010 | ||
CH | 31.03.2010 | ||
LI | 31.03.2010 | ||
MC | 31.03.2010 | ||
BG | 13.04.2010 | ||
GR | 14.04.2010 | ||
PT | 13.05.2010 | ||
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CH | 31.03.2010 | ||
LI | 31.03.2010 | ||
MC | 31.03.2010 | ||
BG | 13.04.2010 | ||
GR | 14.04.2010 | ||
PT | 13.05.2010 | ||
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MC | 31.03.2010 | ||
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PT | 13.05.2010 | ||
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MC | 31.03.2010 | ||
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MC | 31.03.2010 | ||
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MC | 31.03.2010 | ||
GR | 14.04.2010 | ||
PT | 13.05.2010 | ||
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MC | 31.03.2010 | ||
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Former [2010/35] | PT | 13.05.2010 | Documents cited: | Search | [XY]US5707853 (MILLAN JOSE L [US]) [X] 6-8 * das ganze Dokument, insbesondere Fig.1C und SEQ ID NO: 9 * [Y] 13-16; | [XY]EP0955369 (ROCHE DIAGNOSTICS GMBH [DE]) [X] 6-8 * das ganze Dokument, insbesondere SEQ ID NO: 2 * [Y] 13-16; | [YA]EP1176205 (ROCHE DIAGNOSTICS GMBH [DE], et al) [Y] 13-16 * das ganze Dokument, insbesondere Ansprüche 1, 4, 5 * [A] 1-12; | [XY] - WEISSIG H ET AL, "CLONING AND EXPRESSION OF THE BOVINE INTESTINAL ALKALINE PHOSPHATASE GENE: BIOCHEMICAL CHARACTERIZATION OF THE RECOMBINANT ENZYME", BIOCHEMICAL JOURNAL, PORTLAND PRESS, LONDON, GB, vol. 290, no. 2, ISSN 0264-6021, (19930301), Database accession no. P19111, pages 503 - 508, URL: EMBL, XP002070998 [X] 6-8 * das ganze Dokument, insbesondere Fig.2 * [Y] 13-16 | [XY] - MANES T ET AL, "GENETIC COMPLEXITY, STRUCTURE, AND CHARACTERIZATION OF HIGHLY ACTIVE BOVINE INTESTINAL ALKALINE PHOSPHATASES", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (19980904), vol. 273, no. 36, ISSN 0021-9258, pages 23353 - 23360, XP001029065 [X] 6-8 * das ganze Dokument, insbesondere Seite 23359 * [Y] 13-16 DOI: http://dx.doi.org/10.1074/jbc.273.36.23353 | [A] - BESMAN M ET AL, "ISOZYMES OF BOVINE INTESTINAL ALKALINE PHOSPHATASE", JOURNAL OF BIOLOGICAL CHEMISTRY. (MICROFILMS), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (19850915), vol. 260, no. 20, pages 11190 - 11193, XP000606610 | [XY] - WEISSIG H ET AL, "Alkaline phosphatase, intestinal precursor (EC 3.1.3.1)", EMBL, EBI, (19901101), Database accession no. P19111, URL: EMBL, XP002259394 [X] 6-8 * s. Sequenz * [Y] 13-16 |