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Extract from the Register of European Patents

EP About this file: EP1348760

EP1348760 - Production of inactive mutants or mutants with a low activity of an alkaline phosphatase and their expression in yeast [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.11.2010
Database last updated on 22.08.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  SE  SI  SK  TR 
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2010/02]For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  SE  SI  SK  TR 
F.HOFFMANN-LA ROCHE AG
Grenzacherstrasse 124
4070 Basel / CH
Former [2003/40]For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  SE  SI  SK  TR 
F.HOFFMANN-LA ROCHE AG
Grenzacherstrasse 124
4070 Basel / CH
Inventor(s)01 / Mueller, Rainer, Dr.
An der Freiheit 54
82377 Penzberg / DE
02 / Thalhofer, Johann-Peter, Dr.
Krottenkopfstrasse 9b
82362 Weilheim / DE
03 / Geipel, Frank, Dr.
Nelkenstrasse 23
82377 Penzberg / DE
04 / Hoelke, Werner, Dr.
An der Freiheit 73
82377 Penzberg / DE
05 / Kirschbaum, Thomas, Dr.
Humboldtstrasse 3
81543 Muenchen / DE
 [2003/40]
Representative(s)Jung, Michael
Roche Diagnostics GmbH Patentabteilung Sandhofer Strasse 116
68305 Mannheim / DE
[N/P]
Former [2003/40]Jung, Michael, Dr.
Roche Diagnostics GmbH Patentabteilung
68298 Mannheim / DE
Application number, filing date03006426.521.03.2003
[2003/40]
Priority number, dateDE200211320125.03.2002         Original published format: DE 10213201
[2003/40]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report 
No.:EP1348760
Date:01.10.2003
Language:DE
[2003/40]
Type: A3 Search report 
No.:EP1348760
Date:07.01.2004
[2004/02]
Type: B1 Patent specification 
No.:EP1348760
Date:13.01.2010
Language:DE
[2010/02]
Search report(s)(Supplementary) European search report - dispatched on:EP20.11.2003
ClassificationIPC:C12N9/16, C12N5/10
[2003/40]
CPC:
C12N9/16 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2003/40]
TitleGerman:Erzeugung von schwach aktiven oder inaktiven Mutanten von Alkalischer Phosphatase und deren Expression in Hefe[2003/40]
English:Production of inactive mutants or mutants with a low activity of an alkaline phosphatase and their expression in yeast[2003/40]
French:Production de mutants d'une phosphatase alcaline inactifs ou ayant une activité reduite et leur expression dans la levure[2003/40]
Examination procedure07.07.2004Examination requested  [2004/37]
10.08.2004Despatch of a communication from the examining division (Time limit: M06)
11.01.2005Reply to a communication from the examining division
19.03.2007Despatch of a communication from the examining division (Time limit: M04)
14.07.2007Reply to a communication from the examining division
11.05.2009Despatch of a communication from the examining division (Time limit: M04)
27.05.2009Reply to a communication from the examining division
07.08.2009Communication of intention to grant the patent
27.11.2009Fee for grant paid
27.11.2009Fee for publishing/printing paid
Opposition(s)14.10.2010No opposition filed within time limit [2010/51]
Fees paidRenewal fee
04.03.2005Renewal fee patent year 03
06.03.2006Renewal fee patent year 04
05.03.2007Renewal fee patent year 05
10.03.2008Renewal fee patent year 06
06.03.2009Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY13.01.2010
CZ13.01.2010
DK13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
TR13.01.2010
AT21.03.2010
LU21.03.2010
BE31.03.2010
CH31.03.2010
LI31.03.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
HU14.07.2010
[2012/47]
Former [2012/43]CY13.01.2010
CZ13.01.2010
DK13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
AT21.03.2010
LU21.03.2010
BE31.03.2010
CH31.03.2010
LI31.03.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
HU14.07.2010
Former [2012/42]CY13.01.2010
CZ13.01.2010
DK13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
AT21.03.2010
BE31.03.2010
CH31.03.2010
LI31.03.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
HU14.07.2010
Former [2011/43]CY13.01.2010
CZ13.01.2010
DK13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
AT21.03.2010
BE31.03.2010
CH31.03.2010
LI31.03.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
Former [2011/14]CY13.01.2010
CZ13.01.2010
DK13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
BE31.03.2010
CH31.03.2010
LI31.03.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
Former [2011/10]CY13.01.2010
CZ13.01.2010
DK13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
CH31.03.2010
LI31.03.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
Former [2011/07]CY13.01.2010
CZ13.01.2010
DK13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
Former [2010/51]CY13.01.2010
CZ13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
MC31.03.2010
BG13.04.2010
GR14.04.2010
PT13.05.2010
Former [2010/49]CY13.01.2010
CZ13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
SK13.01.2010
MC31.03.2010
GR14.04.2010
PT13.05.2010
Former [2010/48]CY13.01.2010
EE13.01.2010
FI13.01.2010
IE13.01.2010
RO13.01.2010
SE13.01.2010
SI13.01.2010
MC31.03.2010
GR14.04.2010
PT13.05.2010
Former [2010/46]FI13.01.2010
IE13.01.2010
SI13.01.2010
MC31.03.2010
GR14.04.2010
PT13.05.2010
Former [2010/38]FI13.01.2010
SI13.01.2010
PT13.05.2010
Former [2010/36]SI13.01.2010
PT13.05.2010
Former [2010/35]PT13.05.2010
Documents cited:Search[XY]US5707853  (MILLAN JOSE L [US]) [X] 6-8 * das ganze Dokument, insbesondere Fig.1C und SEQ ID NO: 9 * [Y] 13-16;
 [XY]EP0955369  (ROCHE DIAGNOSTICS GMBH [DE]) [X] 6-8 * das ganze Dokument, insbesondere SEQ ID NO: 2 * [Y] 13-16;
 [YA]EP1176205  (ROCHE DIAGNOSTICS GMBH [DE], et al) [Y] 13-16 * das ganze Dokument, insbesondere Ansprüche 1, 4, 5 * [A] 1-12;
 [XY]  - WEISSIG H ET AL, "CLONING AND EXPRESSION OF THE BOVINE INTESTINAL ALKALINE PHOSPHATASE GENE: BIOCHEMICAL CHARACTERIZATION OF THE RECOMBINANT ENZYME", BIOCHEMICAL JOURNAL, PORTLAND PRESS, LONDON, GB, vol. 290, no. 2, ISSN 0264-6021, (19930301), Database accession no. P19111, pages 503 - 508, URL: EMBL, XP002070998 [X] 6-8 * das ganze Dokument, insbesondere Fig.2 * [Y] 13-16
 [XY]  - MANES T ET AL, "GENETIC COMPLEXITY, STRUCTURE, AND CHARACTERIZATION OF HIGHLY ACTIVE BOVINE INTESTINAL ALKALINE PHOSPHATASES", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (19980904), vol. 273, no. 36, ISSN 0021-9258, pages 23353 - 23360, XP001029065 [X] 6-8 * das ganze Dokument, insbesondere Seite 23359 * [Y] 13-16

DOI:   http://dx.doi.org/10.1074/jbc.273.36.23353
 [A]  - BESMAN M ET AL, "ISOZYMES OF BOVINE INTESTINAL ALKALINE PHOSPHATASE", JOURNAL OF BIOLOGICAL CHEMISTRY. (MICROFILMS), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (19850915), vol. 260, no. 20, pages 11190 - 11193, XP000606610
 [XY]  - WEISSIG H ET AL, "Alkaline phosphatase, intestinal precursor (EC 3.1.3.1)", EMBL, EBI, (19901101), Database accession no. P19111, URL: EMBL, XP002259394 [X] 6-8 * s. Sequenz * [Y] 13-16
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.