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Extract from the Register of European Patents

EP About this file: EP1484394

EP1484394 - PRIMERS FOR NUCLEIC ACID AMPLIFICATION IN DETECTING HOUSEKEEPING GENE MRNA AND TEST METHOD USING THESE PRIMERS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  30.10.2009
Database last updated on 03.10.2024
Most recent event   Tooltip30.10.2009Application deemed to be withdrawnpublished on 02.12.2009  [2009/49]
Applicant(s)For all designated states
SYSMEX CORPORATION
1-5-1, Wakinohama-Kaigandori, Chuo-ku Kobe-shi
Hyogo 651-0073 / JP
[N/P]
Former [2004/50]For all designated states
Sysmex Corporation
1-5-1, Wakinohama-Kaigandori, Chuo-ku
Kobe-shi, Hyogo 651-0073 / JP
Inventor(s)01 / TADA, Sachiyo, c/o SYSMEX CORPORATION
5-1, Wakinohama-kaigandori 1-chome, Chuo-ku
Kobe-shi, Hyogo 651-0073 / JP
 [2004/50]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[N/P]
Former [2004/50]HOFFMANN - EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date03705099.413.02.2003
[2004/50]
WO2003JP01474
Priority number, dateJP2002004386620.02.2002         Original published format: JP 2002043866
JP2002004386720.02.2002         Original published format: JP 2002043867
[2004/50]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03070935
Date:28.08.2003
Language:EN
[2003/35]
Type: A1 Application with search report 
No.:EP1484394
Date:08.12.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 28.08.2003 takes the place of the publication of the European patent application.
[2004/50]
Search report(s)International search report - published on:JP28.08.2003
(Supplementary) European search report - dispatched on:EP22.09.2005
ClassificationIPC:C12N15/09, C12Q1/68
[2004/50]
CPC:
C12Q1/6876 (EP,US); C12Q1/6851 (EP,US); C12Q2545/101 (EP,US);
C12Q2600/158 (EP,US); C12Q2600/16 (EP,US); C12Q2600/166 (EP,US)
C-Set:
C12Q1/6851, C12Q2545/101, C12Q2531/119 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SI,   SK,   TR [2004/50]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
TitleGerman:PRIMER ZUR NUKLEINSÄUREAMPLIFIKATION BEIM NACHWEISEN VON HAUSHALTUNGSGEN-mRNA SOWIE TESTVERFAHREN MIT DIESEN PRIMERN[2004/50]
English:PRIMERS FOR NUCLEIC ACID AMPLIFICATION IN DETECTING HOUSEKEEPING GENE MRNA AND TEST METHOD USING THESE PRIMERS[2004/50]
French:AMORCES POUR L'AMPLIFICATION D'ACIDES NUCLEIQUES SERVANT A LA DETECTION DE L'ARNM D'UN GENE DOMESTIQUE ET METHODE D'ESSAI FAISANT INTERVENIR CES AMORCES[2004/50]
Entry into regional phase07.09.2004Translation filed 
07.09.2004National basic fee paid 
07.09.2004Search fee paid 
07.09.2004Designation fee(s) paid 
07.09.2004Examination fee paid 
Examination procedure29.08.2003Request for preliminary examination filed
International Preliminary Examining Authority: JP
07.09.2004Examination requested  [2004/50]
27.11.2008Despatch of a communication from the examining division (Time limit: M06)
09.06.2009Application deemed to be withdrawn, date of legal effect  [2009/49]
14.07.2009Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2009/49]
Divisional application(s)EP09007530.0  / EP2107113
Fees paidRenewal fee
21.02.2005Renewal fee patent year 03
22.02.2006Renewal fee patent year 04
23.02.2007Renewal fee patent year 05
21.02.2008Renewal fee patent year 06
27.03.2008Renewal fee patent year 07
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Documents cited:Search[XA]WO9417086  (APOLLON INC [US], et al) [X] 1-3 * 100% identity in overlap of SEQ ID No 4 (20 nt in length) of the present application and Seq ID No 34 (24 nt in length) of the citation.; page 25 - page 27 * [A] 4,7-13,21,22,24-27;
 [XA]WO9423023  (UNIV ROCHESTER [US]) [X] 1,2,5,7 * pAGE 19, SEQ ID NO 9 of citation is a GAPDH, sense primer (24 bp) that has a 100% identiy to SEQ ID NO 51 between bases 169 to 192.; page 14, paragraph 1 * [A] 14-21,23-27;
 [XA]WO9738098  (UNIV MANITOBA [CA], et al) [X] 1-4,7 * Forward primer of 32 bp shows a 100% identity in overlap with SEQ ID No 1 between nt 253 to nt 284.; page 30, line 31 - line 36 * [A] 8-13,21,22,24-27;
 [X]WO9831707  (BMRA CORP BV [NL]) [X] 1,2,7 * 21 nt GAPDH primer of SEQ ID No 5 of the citation has a 100% overlap with SEQ ID No 53 (20 nt in length) of the present application.; page 24 - page 25; example 4 *;
 [X]WO9940221  (DAHM MICHAEL W [DE], et al) [X] 1,2 * page 16, paragraph 5 - page 17, paragraph 3; sequences ACT1,ACT2 *;
 [X]WO9954510  (GENENTECH INC [US]) [X] 1,2 * page 12 - page 13; tables 1a,1b *;
 [XA]WO9967634  (UNIV CALIFORNIA [US]) [X] 1,2,5,7 * Page 15, Seq ID No 20 of citatation is an antisense GAPDH primer (29 bp) that has a 100% identity to SEQ ID 51 of the application between bases 387 to 414; page 22, line 5. * [A] 14-21,23-27;
 [X]DE19909503  (BOEHRINGER INGELHEIM INT [DE]) [X] 1,2,5* GAPDH primer, SEQ ID NO 25 of citation, has a 100% identity in overlap in 20 bp with the 22 bp primer, SEq ID No 52, of the present application. *;
 [A]WO0077972  (GEN INSTRUMENT CORP [US], et al) [A] 3 * Example 4: SEQ ID No 13 of citation (22 nt in length) has a 100% identity in, ungapped overlap of 13 nt with SEQ ID No 2 (16 nt in length) of the present application. *;
 [X]US6258543  (GERDES JOHN C [US], et al) [X] 1,2,5,7 * Probe, Seq ID No 7 of the citation (30 nt in length) corresponds to the region 114 -143 of SEQ ID No 51 relating to GAPDH gene fragment of the present application.; column 3, lines 5-10; table 1 *
International search[X]JPH07123984  (HITACHI CHEMICAL CO LTD);
 [Y]WO9858083  (OHIO MED COLLEGE [US], et al);
 [Y]WO0028082  (EIKEN CHEMICAL [JP], et al);
 [Y]  - DUMOULIN F.L. ET AL., "Semiquantitation of human chemokine mRNA levels with a newly constructed multispecific competitor fragment", J. IMMUNOL. METHODS, (1999), vol. 224, no. 1-2, pages 61 - 67, XP004165510

DOI:   http://dx.doi.org/10.1016/S0022-1759(99)00009-5
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