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Extract from the Register of European Patents

EP About this file: EP1483256

EP1483256 - PROCESS FOR MAKING CHIRAL 1,4-DISUBSTITUTED PIPERAZINES [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  24.07.2009
Database last updated on 19.10.2024
Most recent event   Tooltip24.07.2009Withdrawal of applicationpublished on 26.08.2009  [2009/35]
Applicant(s)For all designated states
Wyeth
Five Giralda Farms
Madison, NJ 07940-0874 / US
[N/P]
Former [2004/50]For all designated states
Wyeth
Five Giralda Farms
Madison, New Jersey 07940-0874 / US
Inventor(s)01 / JIRKOVSKY, Ivo
P.O. Box 1209
Waitsfield, VT 05673 / US
02 / ZELDIS, Joseph
195 Long Clove Road
New City, NY 10956 / US
03 / FEIGELSON, Gregg, Brian
One Independence Lane
Monsey, NY 10952 / US
 [2004/50]
Representative(s)Bradley, Adrian
Wyeth Pharmaceuticals, Patent Department
Huntercombe Lane South
Taplow
Maidenhead, Berkshire SL6 0PH / GB
[N/P]
Former [2004/50]Bradley, Adrian, Dr.
Wyeth Pharmaceuticals, Patent Department Huntercombe Lane South Taplow
Maidenhead, Berkshire SL6 0PH / GB
Application number, filing date03716403.510.03.2003
[2004/50]
WO2003US07176
Priority number, dateUS20020363458P12.03.2002         Original published format: US 363458 P
[2004/50]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03078420
Date:25.09.2003
Language:EN
[2003/39]
Type: A2 Application without search report 
No.:EP1483256
Date:08.12.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 25.09.2003 takes the place of the publication of the European patent application.
[2004/50]
Search report(s)International search report - published on:EP11.03.2004
ClassificationIPC:C07D401/00
[2004/50]
CPC:
C07D487/10 (EP,US); C07D405/06 (KR); A61P25/00 (EP);
C07C229/12 (EP,US); C07C309/06 (EP,US); C07D319/18 (EP,US);
C07D405/10 (KR); C07B2200/07 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2004/50]
Extension statesAL07.09.2004
LT07.09.2004
LV07.09.2004
MK07.09.2004
TitleGerman:VERFAHREN ZUR HERSTELLUNG CHIRALER 1,4-DISUBSTITUIERTER PIPERAZINE[2004/50]
English:PROCESS FOR MAKING CHIRAL 1,4-DISUBSTITUTED PIPERAZINES[2004/50]
French:METHODE DE PRODUCTION DE PIPERAZINES CHIRAUX 1,4-DISUBSTITUES[2004/50]
Entry into regional phase07.09.2004National basic fee paid 
07.09.2004Designation fee(s) paid 
07.09.2004Examination fee paid 
Examination procedure24.09.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
07.09.2004Examination requested  [2004/50]
13.02.2009Communication of intention to grant the patent
21.07.2009Application withdrawn by applicant  [2009/35]
Fees paidRenewal fee
04.03.2005Renewal fee patent year 03
06.03.2006Renewal fee patent year 04
05.03.2007Renewal fee patent year 05
10.03.2008Renewal fee patent year 06
06.03.2009Renewal fee patent year 07
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Cited inInternational search[A]DE960203  (YOSHITOMI PHARMACEUTICAL) [A] 10 * examples 1-4; claim 1 *;
 [A]  - CROSSFIRE BEILSTEIN, Beilstein Institut zur Förderung der Chemischen Wissenschaften, Frankfurt am Main, DE, Database accession no. 3915193, XP002252515 [A] 10 * abstract *
    [ ] - G. AIKO, PHARM. BULL., (1957), vol. 5, page 487
 [A]  - CROSSFIRE BEILSTEIN, Beilstein Institut zur Förderung der Chemischen Wissenschaften, Frankfurt am Main, DE, Database accession no. 1512459, XP002252516 [A] 1-15 * abstract *
    [ ] - F. EFFENBERGER ET AL., LIEBIGS ANN. CHEM., (1986), no. 2, pages 314 - 333
 [A]  - S. J. STACHEL ET AL., "A Chiral C3 Triisopropylamine and its Silatrane Derivatives", TETRAHEDON LETTERS, (1999), vol. 40, pages 5811 - 5812, XP002252511 [A] 1-10 * Scheme 1 *

DOI:   http://dx.doi.org/10.1016/S0040-4039(99)01135-1
 [A]  - J. M. C. GOLEC ET AL., "Structure-based design of non-peptidic pyridone aldehydes as inhibitors of interleukin-1.beta. converting enzyme", BIORG. MED. CHEM. LETT., (1997), vol. 7, no. 17, pages 2181 - 2186, XP002252512 [A] 1-10 * Scheme 1 *

DOI:   http://dx.doi.org/10.1016/S0960-894X(97)00394-6
 [A]  - D. MULLER ET AL., "Building Units for N-Backbone Cyclic Peptides. 3. Synthesis of Protected N.alpha.-(.omega.-Aminoalkyl)amino Acids and N.alpha.-(.omega.-Carboxyalkyl)amino Acids", J. ORG. CHEM., (1997), vol. 62, no. 2, pages 411 - 416, XP002252513 [A] 1-10 * Scheme 3 *

DOI:   http://dx.doi.org/10.1021/jo961580e
 [A]  - G. M. TAYLOR ET AL., "On The Ritter Reaction of Cyclic Hydroxyamines: Synthesis of Conformationally-Restricted Reduced Amide Dipeptide Isosteres", TETRAHEDRON LETTERS, (1996), vol. 37, no. 8, pages 1297 - 1300, XP002252514 [A] 1-10 * figure 1 *

DOI:   http://dx.doi.org/10.1016/0040-4039(95)02378-X
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