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EP About this file: EP1501803

EP1501803 - TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 19.06.2009 Database last updated on 22.08.2024
Most recent event Tooltip	30.09.2011	Lapse of the patent in a contracting state New state(s): CY, TR	published on 02.11.2011 [2011/44]
Applicant(s)	For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 / US
	For all designated states MERCK SHARP & DOHME LTD. Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB
	[2008/33]
Former [2005/05]	For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 / US
	For all designated states MERCK SHARP & DOHME LTD. Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB
Inventor(s)	01 / JIAO, Richard 540 Collings Avenue, Suite A705 Collingswood, New Jersey 08107 / US
	02 / GOBLE, Stephen, D. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	03 / MILLS, Sander, G. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	04 / MORRIELLO, Gregori 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	05 / PASTERNAK, Alexander 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	06 / YANG, Lihu 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	07 / ZHOU, Changyou 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	08 / BUTORA, Gabor 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	09 / KOTHANDARAMAN, Shankaran 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	10 / GUIADEEN, Deodialsingh 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	11 / MOYES, Christopher Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB
	[2005/19]
Former [2005/05]	01 / JIAO, Richard 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	02 / GOBLE, Stephen, D. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	03 / MILLS, Sander, G. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	04 / MORRIELLO, Gregori 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	05 / PASTERNAK, Alexander 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	06 / YANG, Lihu 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	07 / ZHOU, Changyou 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	08 / BUTORA, Gabor 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	09 / KOTHANDARAMAN, Shankaran 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	10 / GUIADEEN, Deodialsingh 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US
	11 / MOYES, Christopher Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB
Representative(s)	Man, Jocelyn, et al Merck & Co., Inc. European Patent Department Merck Sharp & Dohme Limited Hertford Road, Hoddesdon Hertfordshire, EN11 9BU / GB
	[N/P]
Former [2006/48]	Man, Jocelyn, et al Merck & Co., Inc. European Patent Department Merck Sharp & Dohme Limited, Hertford Road, Hoddesdon Hertfordshire, EN11 9BU / GB
Former [2005/05]	Man, Jocelyn Merck & Co.,Inc., European Patent Department, Terlings Park, Eastwick Road Harlow, Essex CM20 2QR / GB
Application number, filing date	03719958.5	25.04.2003
	[2005/05]
	WO2003US13121
Priority number, date	US20020376407P	29.04.2002 Original published format: US 376407 P
	[2005/05]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO03093231
	Date:	13.11.2003
	Language:	EN
	[2003/46]
	Type:	A2 Application without search report
	No.:	EP1501803
	Date:	02.02.2005
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 13.11.2003 takes the place of the publication of the European patent application.
	[2005/05]
	Type:	B1 Patent specification
	No.:	EP1501803
	Date:	13.08.2008
	Language:	EN
	[2008/33]
Search report(s)	International search report - published on:	US	12.08.2004
	(Supplementary) European search report - dispatched on:	EP	09.03.2006
Classification	IPC:	C07D217/00, A61K31/47, C07D405/12, C07D401/12, C07D217/06, A61P29/00	[2006/17]
	CPC:	C07D231/12 (EP,US); A61P1/04 (EP); A61P11/00 (EP); A61P11/06 (EP); A61P13/12 (EP); A61P21/04 (EP); (+) A61P29/00 (EP); A61P3/10 (EP); A61P33/10 (EP); A61P35/00 (EP); A61P37/02 (EP); A61P37/08 (EP); A61P43/00 (EP); C07D217/06 (EP,US); C07D233/56 (EP,US); C07D249/08 (EP,US); C07D401/12 (EP,US); C07D401/14 (EP,US); C07D405/12 (EP,US); C07D405/14 (EP,US); C07D491/04 (EP,US); C07D491/052 (EP,US) (-)
	Former IPC [2005/05]	C07D217/00, A61K31/47
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, RO, SE, SI, SK, TR [2005/05]
Extension states	AL	Not yet paid
	LT	14.02.2005
	LV	14.02.2005
	MK	Not yet paid
Title	German:	TETRAHYDROPYRANYLCYCLOPENTYLTETRAHYDROISOCHINO-LINMODULATOREN DER CHEMOKINREZEPTORAKTIVITÄT	[2005/05]
	English:	TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY	[2005/05]
	French:	MODULATEURS DE L'ACTIVITE DES RECEPTEURS DES CHIMIOKINES A BASE DE TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE	[2005/05]
Entry into regional phase	29.11.2004	National basic fee paid
	29.11.2004	Search fee paid
	14.02.2005	Designation fee(s) paid
	14.02.2005	Examination fee paid
Examination procedure	18.11.2003	Request for preliminary examination filed International Preliminary Examining Authority: US
	08.11.2004	Amendment by applicant (claims and/or description)
	14.02.2005	Examination requested [2005/15]
	25.01.2008	Communication of intention to grant the patent
	04.06.2008	Fee for grant paid
	04.06.2008	Fee for publishing/printing paid
Opposition(s)	14.05.2009	No opposition filed within time limit [2009/30]
Fees paid	Renewal fee
	04.04.2005	Renewal fee patent year 03
	27.03.2006	Renewal fee patent year 04
	10.04.2007	Renewal fee patent year 05
	18.03.2008	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	AT	13.08.2008
	BE	13.08.2008
	CY	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	IT	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	TR	13.08.2008
	BG	13.11.2008
	SE	13.11.2008
	GR	14.11.2008
	ES	24.11.2008
	PT	13.01.2009
	HU	14.02.2009
	IE	25.04.2009
	LU	25.04.2009
	MC	30.04.2009
	[2011/43]
Former [2011/31]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	IT	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	SE	13.11.2008
	GR	14.11.2008
	ES	24.11.2008
	PT	13.01.2009
	HU	14.02.2009
	IE	25.04.2009
	LU	25.04.2009
	MC	30.04.2009
Former [2011/21]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	IT	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	SE	13.11.2008
	GR	14.11.2008
	ES	24.11.2008
	PT	13.01.2009
	IE	25.04.2009
	LU	25.04.2009
	MC	30.04.2009
Former [2010/48]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	IT	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	SE	13.11.2008
	GR	14.11.2008
	ES	24.11.2008
	PT	13.01.2009
	IE	25.04.2009
	MC	30.04.2009
Former [2010/21]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	IT	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	SE	13.11.2008
	ES	24.11.2008
	PT	13.01.2009
	IE	25.04.2009
	MC	30.04.2009
Former [2010/09]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	IT	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	SE	13.11.2008
	ES	24.11.2008
	PT	13.01.2009
Former [2009/39]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	IT	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	ES	24.11.2008
	PT	13.01.2009
Former [2009/36]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	EE	13.08.2008
	FI	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	ES	24.11.2008
	PT	13.01.2009
Former [2009/25]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	FI	13.08.2008
	NL	13.08.2008
	RO	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	ES	24.11.2008
	PT	13.01.2009
Former [2009/24]	AT	13.08.2008
	BE	13.08.2008
	CZ	13.08.2008
	DK	13.08.2008
	FI	13.08.2008
	NL	13.08.2008
	SI	13.08.2008
	SK	13.08.2008
	BG	13.11.2008
	ES	24.11.2008
Former [2009/23]	AT	13.08.2008
	BE	13.08.2008
	DK	13.08.2008
	FI	13.08.2008
	NL	13.08.2008
	SI	13.08.2008
	BG	13.11.2008
	ES	24.11.2008
Former [2009/19]	AT	13.08.2008
	BE	13.08.2008
	DK	13.08.2008
	FI	13.08.2008
	NL	13.08.2008
	SI	13.08.2008
	ES	24.11.2008
Former [2009/15]	AT	13.08.2008
	FI	13.08.2008
	NL	13.08.2008
	SI	13.08.2008
	ES	24.11.2008
Former [2009/12]	FI	13.08.2008
	NL	13.08.2008
	ES	24.11.2008
Former [2009/09]	NL	13.08.2008
	ES	24.11.2008
Documents cited:	Search	[ ] - No further relevant documents disclosed
	International search	[A]US5691321 (SCHAPER WOLFGANG [DE], et al);
		[A] - VAN RIPER ET AL, "Characterization and species distribution of high affinity GTP-coupled receptorsfor human rantes and monocyte chemoattractant protein 1", J. EXP. MED., (199303), vol. 177, pages 851 - 856, XP002978102 DOI: http://dx.doi.org/10.1084/jem.177.3.851
	Examination	WO0213824

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