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Extract from the Register of European Patents

EP About this file: EP1499329

EP1499329 - USE OF XENON FOR THE CONTROL OF NEUROLOGICAL DEFICITS ASSOCIATED WITH CARDIOPULMONARY BYPASS [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  21.04.2012
Database last updated on 29.07.2024
Most recent event   Tooltip17.04.2015Change - lapse in a contracting state
New state(s): CY, NL, TR
published on 20.05.2015  [2015/21]
Applicant(s)For all designated states
Protexeon Limited
Aldwych House, 81 Aldwich
London WC2B 4HN / GB
[2009/15]
Former [2005/04]For all designated states
Protexeon Limited
Aldwych House, 81 Aldwich
London WC2B 4HN / GB
Inventor(s)01 / FRANKS, N.P.@Blackett Lab.@Imp. College of Science
Technology and Medicine
Prince Consort Road
London SW7 2BZ / GB
02 / MAZE, M.@Sir Ivan Magill Dept. of Anaesthetics, @Imperial College School of Medicine
Chelsea and Westminsterter Hosp.
369 Fulham Road
London SW10 9NH / GB
 [2012/21]
Former [2009/15]01 / FRANKS, N.P. Blackett Lab. Imp. College of Science
Technology and Medicine Prince Consort Road
London SW7 2BZ / GB
02 / MAZE, M. Sir Ivan Magill Dept. of Anaesthetics, Imperial College School of Medicine
Chelsea and Westminsterter Hosp. 369 Fulham Road
London SW10 9NH / GB
Former [2005/04]01 / FRANKS, N.P. Blackett Lab. Imp. College of Science
Technology and Medicine Prince Consort Road
London SW7 2BZ / GB
02 / MAZE, M. Sir Ivan Magill Dept. of Anaesthetics
Chelsea and Westminsterter Hosp. 369 Fulham Road
London SW10 9NH / GB
Representative(s)Clyde-Watson, Zöe, et al
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
[N/P]
Former [2012/21]Clyde-Watson, Zöe, et al
D Young & Co LLP 120 Holborn
London EC1N 2DY / GB
Former [2005/04]Clyde-Watson, Zöe, et al
D Young & Co 120 Holborn
London EC1N 2DY / GB
Application number, filing date03725356.401.05.2003
[2005/04]
WO2003GB01867
Priority number, dateGB2002000999801.05.2002         Original published format: GB 0209998
[2005/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03092707
Date:13.11.2003
Language:EN
[2003/46]
Type: A1 Application with search report 
No.:EP1499329
Date:26.01.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 13.11.2003 takes the place of the publication of the European patent application.
[2005/04]
Type: B1 Patent specification 
No.:EP1499329
Date:08.04.2009
Language:EN
[2009/15]
Type: B2 New European patent specification 
No.:EP1499329
Date:23.05.2012
Language:EN
[2012/21]
Search report(s)International search report - published on:EP13.11.2003
ClassificationIPC:A61K33/00, A61P25/28, A61P41/00, A61K9/72
[2005/04]
CPC:
A61K33/00 (EP,US); A61P25/00 (EP); A61P25/28 (EP);
A61P41/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/04]
TitleGerman:VERWENDUNG VON XENON ZUR KONTROLLE VON NEUROLOGISCHEN DEFIZITEN IM ZUSAMMENHANG MIT KARDIOPULMONALEM BYPASS[2005/04]
English:USE OF XENON FOR THE CONTROL OF NEUROLOGICAL DEFICITS ASSOCIATED WITH CARDIOPULMONARY BYPASS[2005/04]
French:UTILISATION DU XENON DANS LA SURVEILLANCE DES DEFICITS NEUROLOGIQUES ASSOCIES A LA CIRCULATION EXTRACORPORELLE[2005/04]
Entry into regional phase17.11.2004National basic fee paid 
17.11.2004Designation fee(s) paid 
17.11.2004Examination fee paid 
Examination procedure26.11.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
17.11.2004Examination requested  [2005/04]
11.01.2005Amendment by applicant (claims and/or description)
22.04.2008Despatch of a communication from the examining division (Time limit: M04)
19.08.2008Reply to a communication from the examining division
03.11.2008Communication of intention to grant the patent
19.02.2009Fee for grant paid
19.02.2009Fee for publishing/printing paid
Opposition(s)Opponent(s)01  04.12.2009    ADMISSIBLE
L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE
75, Quai d'Orsay
75007 Paris / FR
Opponent's representative
Pittis, Olivier, et al, et al
L'Air Liquide, S.A.
Direction de la Propriété Intellectuelle
75, Quai d'Orsay
75321 Paris Cedex 07 / FR
 [N/P]
Former [2010/02]
Opponent(s)01  04.12.2009    ADMISSIBLE
L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE
75, Quai d'Orsay
75007 Paris / FR
Opponent's representative
Pittis, Olivier, et al, et al
L'Air Liquide, S.A., Direction de la Propriété Intellectuelle, 75, Quai d'Orsay
75321 Paris Cedex 07 / FR
12.02.2010Invitation to proprietor to file observations on the notice of opposition
19.08.2010Reply of patent proprietor to notice(s) of opposition
07.07.2011Legal effect of interlocutory decision in opposition
07.07.2011Date of oral proceedings
05.10.2011Despatch of interlocutory decision in opposition
05.10.2011Despatch of minutes of oral proceedings
20.01.2012Despatch of communication that the patent will be maintained as amended
30.03.2012Fee for printing new specification paid
Fees paidRenewal fee
10.05.2005Renewal fee patent year 03
22.03.2006Renewal fee patent year 04
15.05.2007Renewal fee patent year 05
20.03.2008Renewal fee patent year 06
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competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT08.04.2009
CY08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
SK08.04.2009
TR08.04.2009
IE01.05.2009
LU01.05.2009
MC31.05.2009
BG08.07.2009
GR09.07.2009
PT08.09.2009
HU09.10.2009
NL01.12.2011
[2015/21]
Former [2011/31]AT08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
SK08.04.2009
IE01.05.2009
LU01.05.2009
MC31.05.2009
BG08.07.2009
GR09.07.2009
PT08.09.2009
HU09.10.2009
Former [2011/21]AT08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
SK08.04.2009
IE01.05.2009
LU01.05.2009
MC31.05.2009
BG08.07.2009
GR09.07.2009
PT08.09.2009
Former [2010/48]AT08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
SK08.04.2009
IE01.05.2009
MC31.05.2009
BG08.07.2009
GR09.07.2009
PT08.09.2009
Former [2010/21]AT08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
SK08.04.2009
IE01.05.2009
MC31.05.2009
BG08.07.2009
PT08.09.2009
Former [2010/18]AT08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
SK08.04.2009
MC31.05.2009
BG08.07.2009
PT08.09.2009
Former [2010/10]AT08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
SK08.04.2009
MC31.05.2009
PT08.09.2009
Former [2010/09]AT08.04.2009
CZ08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
RO08.04.2009
SI08.04.2009
MC31.05.2009
PT08.09.2009
Former [2010/08]AT08.04.2009
DK08.04.2009
EE08.04.2009
FI08.04.2009
SI08.04.2009
MC31.05.2009
PT08.09.2009
Former [2010/04]AT08.04.2009
FI08.04.2009
SI08.04.2009
MC31.05.2009
PT08.09.2009
Former [2009/49]AT08.04.2009
FI08.04.2009
SI08.04.2009
PT08.09.2009
Former [2009/36]SI08.04.2009
Cited inInternational search[X]WO0053192  (AGA AB [SE], et al) [X] 1-32 * the whole document * * page 5, lines 11-20 * * page 6, lines 7-25 * * claims 1-3,9-19 *;
 [YD]WO0076545  (IMPERIAL COLLEGE [GB], et al) [YD] 1-32 * the whole document * * page 17, lines 15-32 * * page 23, line 24 - page 24, line 25; example 4 * * page 18, lines 26-33 *;
 [YD]WO0108692  (IMPERIAL COLLEGE [GB], et al) [YD] 1-32 * the whole document * * page 1, lines 1-15 * * page 20, lines 19,20 ** page 6, lines 26-29 *;
 [PX]  - MA DAQING ET AL, "Xenon Attenuates Cardiopulmonary Bypass-Induced Neurologic and Neurocognitive Dysfunction in the Rat.", ANESTHESIOLOGY ABSTRACTS OF SCIENTIFIC PAPERS ANNUAL MEETING, 2002 Annual Meeting of the American Society of Anesthesiologists;Orlando, FL, USA; October 12-16, 2002, 2002, (2002), no. 2002, pages Abstract No. A - 807, XP001154264 [PX] 1-32 * the whole document *
 [YD]  - GARDNER T J ET AL, "Stroke following coronary artery bypass grafting: a ten-year study.", THE ANNALS OF THORACIC SURGERY. UNITED STATES DEC 1985, (198512), vol. 40, no. 6, ISSN 0003-4975, pages 574 - 581, XP009015316 [YD] 1-32 * the whole document *
 [Y]  - GROCOTT H P ET AL, "Neurological injury during cardiopulmonary bypass in the rat.", PERFUSION. ENGLAND JAN 2001, (200101), vol. 16, no. 1, ISSN 0267-6591, pages 75 - 81, XP009015397 [Y] 1-32 * the whole document * * abstract *
OppositionZA981958
 WO0053192
    - "Xenon als Inhalationsnarkotikum" of Universität Ulm, uni ulm intern, pages 13-14, no 210, January 1997
    - Can J. Physiol Pharmacol, vol. 60, no 11
    - Acta Neuropathol., vol. 90, no 3
    - "Xenon preconditioning reduces brain damage from neonatal asphyxia in rats" Daqing Ma et al., Imperial College London, Journal of Cerebral Blood Flow & Metabolism, 2006, 26, 199-208
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.