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Extract from the Register of European Patents

EP About this file: EP1501837

EP1501837 - CASCADE ESTERS OF CAMPTOTHECINS AND METHODS OF TREATING CANCER USING THESE COMPOUNDS [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  23.01.2009
Database last updated on 08.10.2024
Most recent event   Tooltip06.05.2011Change - representativepublished on 08.06.2011  [2011/23]
Applicant(s)For all designated states
THE STEHLIN FOUNDATION FOR CANCER RESEARCH
1315 St. Joseph Parkway
Houston, TX 77002 / US
[2005/05]
Inventor(s)01 / ZHISONG, Cao
16123 Affirmed Way
Friendswood, TX 77546 / US
02 / BEPPINO, Giovanella, C.
6030 Yarwell
Houston, TX 77096 / US
 [2005/05]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[N/P]
Former [2011/23]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Leopoldstrasse 4
80802 München / DE
Former [2005/05]Grünecker, August, Dipl.-Ing.
Patentanwälte Grünecker, Kinkeldey, Stockmair & Partner Maximilianstrasse 58
80538 München / DE
Application number, filing date03733873.822.04.2003
[2005/05]
WO2003US12399
Priority number, dateUS2002013977806.05.2002         Original published format: US 139778
[2005/05]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03095460
Date:20.11.2003
Language:EN
[2003/47]
Type: A1 Application with search report 
No.:EP1501837
Date:02.02.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 20.11.2003 takes the place of the publication of the European patent application.
[2005/05]
Search report(s)International search report - published on:EP20.11.2003
ClassificationIPC:C07D491/22, A61K31/435, A61P35/00, // (C07D491/22, 331:00, 221:00, 221:00), C07D209:00
[2005/05]
CPC:
C07D491/22 (EP,US); A61P35/00 (EP); A61P43/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/05]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:CAMPTOTHECIN KASKADEN ESTERS UND IHRE VERWENDUNG IN METHODEN ZUR BEHANDLUNG VON KREBS[2005/05]
English:CASCADE ESTERS OF CAMPTOTHECINS AND METHODS OF TREATING CANCER USING THESE COMPOUNDS[2005/05]
French:ESTERS EN CASCADE DE CAMPTOTHECINE ET TECHNIQUES DE TRAITEMENT UTILISANT CES COMPOSES[2005/05]
Entry into regional phase03.11.2004National basic fee paid 
03.11.2004Designation fee(s) paid 
03.11.2004Examination fee paid 
Examination procedure03.11.2004Amendment by applicant (claims and/or description)
03.11.2004Examination requested  [2005/05]
11.03.2005Despatch of a communication from the examining division (Time limit: M07)
13.10.2005Reply to a communication from the examining division
27.07.2006Despatch of a communication from the examining division (Time limit: M04)
01.12.2006Reply to a communication from the examining division
23.06.2008Date of oral proceedings
08.10.2008Minutes of oral proceedings despatched
09.10.2008Despatch of communication that the application is refused, reason: substantive examination [2009/09]
19.10.2008Application refused, date of legal effect [2009/09]
Divisional application(s)EP08011270.9   Application deemed to be withdrawn  : 22.07.2008
Fees paidRenewal fee
27.04.2005Renewal fee patent year 03
17.03.2006Renewal fee patent year 04
27.04.2007Renewal fee patent year 05
25.04.2008Renewal fee patent year 06
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Cited inInternational search[A]US5880131  (GREENWALD RICHARD B [US], et al) [A] 1,7 * column 19, line 5 - line 7; claim 1 *;
 [X]US5965566  (GREENWALD RICHARD B [US], et al) [X] 1,21 * example 3 *;
 [A]US6040313  (WALL MONROE E [US], et al) [A] 1,7 * claim 1 * * column 7, line 20 - line 36 *;
 [A]US2001031761  (CAO ZHISONG [US], et al) [A] 1,7* paragraphs [0052] , [0054]; claim 1 *;
 [A]US6350756  (YANG LI-XI [US], et al) [A] 1,7 * column 3, line 45 - line 64; claim 1 *;
 [A]US2002049324  (CAO ZHISONG [US], et al) [A] 1,7 * paragraphs [0036] , [0042]; claim 1 *;
 [X]  - GREENWALD R B ET AL, "CAMPTOTHECIN-20-PEG ESTER TRANSPORT FORMS: THE EFFECT OF SPACER GROUPS ON ANTITUMOR ACTIVITY", BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER SCIENCE LTD, GB, (1998), vol. 6, ISSN 0968-0896, pages 551 - 562, XP000985272 [X] 1,21 * page 560, column 1; example 15 * * page 557, column 2, line 5 - line 7 *

DOI:   http://dx.doi.org/10.1016/S0968-0896(98)00005-4
 [A]  - WALL M E ET AL, "Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (199302), vol. 36, ISSN 0022-2623, pages 2689 - 2700, XP002122403 [A] 1,7 * page 2693, column 1; examples 7G,7J,7L *

DOI:   http://dx.doi.org/10.1021/jm00070a013
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.