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Extract from the Register of European Patents

EP About this file: EP1485360

EP1485360 - SODIUM CHANNEL BLOCKERS [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 22.06.2012 Database last updated on 24.01.2025
Most recent event Tooltip	22.06.2012	No opposition filed within time limit	published on 25.07.2012 [2012/30]
Applicant(s)	For all designated states Parion Sciences, Inc. 2525 Meridian Parkway Suite 260 Durham, NC 27713 / US
	[N/P]
Former [2011/33]	For all designated states Parion Sciences, Inc. 2525 Meridian Parkway, Suite 260 Durham, NC 27713 / US
Former [2005/14]	For all designated states Parion Sciences, Inc. 2525 Meridian Parkway, Suite 260 Durham, NC 27713 / US
Former [2004/51]	For all designated states Johnson, Michael R. 53524 Bickett Chapel Hill, NC 27517 / US
Inventor(s)	01 / JOHNSON, Michael, R. 53524 Bickett Chapel Hill, NC 27517 / US
	[2005/14]
Former [2004/51]	01 / see applicant ...
Representative(s)	Reitstötter Kinzebach Patentanwälte Postfach 86 06 49 81633 München / DE
	[N/P]
Former [2009/25]	Reitstötter - Kinzebach Patentanwälte Postfach 86 06 49 81633 München / DE
Former [2004/51]	Goulard, Sophie, et al Cabinet ORES, 36,rue de St Pétersbourg 75008 Paris Cedex / FR
Application number, filing date	03742810.9	19.02.2003
	[2004/51]
	WO2003US04817
Priority number, date	US20020076571	19.02.2002 Original published format: US 76571
	[2004/51]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO03070182
	Date:	28.08.2003
	Language:	EN
	[2003/35]
	Type:	A2 Application without search report
	No.:	EP1485360
	Date:	15.12.2004
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 28.08.2003 takes the place of the publication of the European patent application.
	[2004/51]
	Type:	B1 Patent specification
	No.:	EP1485360
	Date:	17.08.2011
	Language:	EN
	[2011/33]
Search report(s)	International search report - published on:	US	24.12.2003
	(Supplementary) European search report - dispatched on:	EP	01.06.2006
Classification	IPC:	C07D241/26, C07D241/24, A61K31/4965, A61P7/10	[2006/25]
	CPC:	A61K31/4965 (EP,KR,US); A61K31/497 (EP,US); A61K31/706 (EP,KR,US); A61K45/06 (KR,US); A61P1/00 (EP); A61P1/02 (EP); (+) A61P1/04 (EP); A61P1/10 (EP); A61P11/00 (EP); A61P11/02 (EP); A61P11/06 (EP); A61P11/08 (EP); A61P11/10 (EP); A61P11/12 (EP); A61P13/00 (EP); A61P13/02 (EP); A61P15/02 (EP); A61P15/08 (EP); A61P17/00 (EP); A61P17/16 (EP); A61P27/02 (EP); A61P27/16 (EP); A61P29/00 (EP); A61P37/00 (EP); A61P37/02 (EP); A61P43/00 (EP); A61P7/00 (EP); A61P7/10 (EP); A61P9/12 (EP); C07D241/26 (EP,US); C07D241/30 (KR); C07D241/32 (EP,KR,US); C07D405/12 (EP,KR,US); C07H15/26 (EP,KR,US) (-)
	Former IPC [2004/51]	C07D241/28, C07D241/24, A61K31/4965, A61P7/10
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, SE, SI, SK, TR [2004/51]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
Title	German:	NATRIUMKANALBLOCKER	[2004/51]
	English:	SODIUM CHANNEL BLOCKERS	[2004/51]
	French:	BLOQUEURS DE CANAUX SODIUM	[2004/51]
Entry into regional phase	17.09.2004	National basic fee paid
	17.09.2004	Search fee paid
	17.09.2004	Designation fee(s) paid
	17.09.2004	Examination fee paid
Examination procedure	22.09.2003	Request for preliminary examination filed International Preliminary Examining Authority: US
	20.09.2004	Amendment by applicant (claims and/or description)
	20.09.2004	Examination requested [2004/51]
	28.01.2008	Despatch of a communication from the examining division (Time limit: M06)
	09.07.2008	Reply to a communication from the examining division
	22.09.2008	Despatch of a communication from the examining division (Time limit: M06)
	14.01.2009	Reply to a communication from the examining division
	29.07.2009	Despatch of a communication from the examining division (Time limit: M04)
	01.12.2009	Reply to a communication from the examining division
	31.01.2011	Communication of intention to grant the patent
	08.06.2011	Fee for grant paid
	08.06.2011	Fee for publishing/printing paid
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 28.01.2008
Opposition(s)	21.05.2012	No opposition filed within time limit [2012/30]
Fees paid	Renewal fee
	14.02.2005	Renewal fee patent year 03
	14.02.2006	Renewal fee patent year 04
	14.02.2007	Renewal fee patent year 05
	13.02.2008	Renewal fee patent year 06
	13.02.2009	Renewal fee patent year 07
	24.02.2010	Renewal fee patent year 08
	23.02.2011	Renewal fee patent year 09
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X]WO0023023 (UNIV NORTH CAROLINA [US]) [X] 1-6,88-104 * the whole document *;
		[X]WO0105773 (UNIV NORTH CAROLINA [US], et al) [X] 1-6,88-104 * page 1, paragraph 4 - page 6; claim - *;
		[X] - MARIA GIANNAKU,J. DOW, "characterization of the drosophila melanogaster alkali-metal/proton exchanger", THE JOURNAL OF EXPERIMENTAL BIOLOGY, gb, (2001), vol. 204, no. 21, pages 3703 - 3716, XP002381331 [X] 1-6,88-104 * page 3703 - page 3706 *
		[X] - P. BARBRY ET AL., "biochemical identification of 2 types of phenamil binding sites associated with amiloride-sensitive na+ channels", BIOCHEMISTRY., USAMERICAN CHEMICAL SOCIETY. EASTON, PA., (1989), vol. 28, no. 9, pages 3744 - 3749, XP002381332 [X] 1-6,88-104 * page 3744 - page 3745 * DOI: http://dx.doi.org/10.1021/bi00435a018
		[X] - P. BARBRY ET AL., "[3H]phenamil binding protein of the renal epithelium na+ channel.", BIOCHEMISTRY., USAMERICAN CHEMICAL SOCIETY. EASTON, PA., (1990), vol. 29, no. 4, pages 1039 - 1045, XP002381333 [X] 1-6,88-104 * page 1039 - page 1041 * DOI: http://dx.doi.org/10.1021/bi00456a028
		[X] - J. VELLY ET AL., "effects of amiloride and its analogues", EUROPEAN JOURNAL OF PHARMACOLOGY, (1988), vol. 149, no. 1-2, pages 97 - 105, XP002381334 [X] 1-6,88-104 * page 97 - page 102; table 1 * DOI: http://dx.doi.org/10.1016/0014-2999(88)90047-7
		[X] - TH. KLEYMAN ET AL., "the cellular pool of na+ channels in the amphibian cell line a6", JOURNAL OF BIOLOGICAL CHEMISTRY., USAMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, AL., (19890715), vol. 264, no. 20, pages 11995 - 12000, XP002381335 [X] 1-6,88-104 * page 11995 - page 11997; figure 1 *
	International search	[X]US3313813 (CRAGOE JR EDWARD J);
		[X]US3573306 (SHEPARD KENNETH L, et al);
		[X] - BICKING ET AL., "Pyrazine diuretics. I. N-amidino-3-amino-6-halopyrazine carboxamides", J. MED. CHEM., (1965), vol. 8, no. 5, pages 638 - 642, XP002967520 DOI: http://dx.doi.org/10.1021/jm00329a017
		[X] - EPAND ET AL., "Reversal of intrinsic multidrug resistance in Chinese hamster ovary cells by amiloride analogs", BRITISH JOURNAL OF CANCER, (1991), vol. 63, no. 2, pages 247 - 251, XP002967521

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