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Extract from the Register of European Patents

EP About this file: EP1492571

EP1492571 - RADIOLABELLED QUINOLINE AND QUINOLINONE DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  13.04.2018
Database last updated on 25.09.2024
FormerGrant of patent is intended
Status updated on  22.06.2017
Most recent event   Tooltip13.04.2018Application deemed to be withdrawnpublished on 16.05.2018  [2018/20]
Applicant(s)For all designated states
Janssen Pharmaceutica NV
Turnhoutseweg 30
2340 Beerse / BE
[N/P]
Former [2005/01]For all designated states
JANSSEN PHARMACEUTICA N.V.
Turnhoutsebaan 30
2340 Beerse / BE
Inventor(s)01 / LESAGE, Anne S.J., Janssen Pharmaceutica N.V.
Turnhoutseweg 30
B-2340 Beerse / BE
02 / BISCHOFF, François P., Janssen Pharmaceutica N.V.
Turnhoutseweg 30
B-2340 Beerse / BE
03 / JANSSEN, Cornelus G.M., Janssen Pharmaceutica N.V.
Turnhoutseweg 30
B-2340 Beerse / BE
04 / LAVREYSEN, Hilde, Janssen Pharmaceutica N.V.
Turnhoutseweg 30
B-2340 Beerse / BE
 [2005/01]
Representative(s)Daelemans, Frank F.R., et al
Janssen Pharmaceutica N.V. J&J Patent Law Department Turnhoutseweg 30
2340 Beerse / BE
[2007/43]
Former [2005/01]Van Borm, Werner, et al
Janssen Pharmaceutica N.V. J & J Patent Law Department Beerse Turnhoutseweg 30
2340 Beerse / BE
Application number, filing date03745282.826.03.2003
[2005/01]
WO2003EP03240
Priority number, dateEP2002007625429.03.2002         Original published format: EP 02076254
[2005/01]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03082350
Date:09.10.2003
Language:EN
[2003/41]
Type: A2 Application without search report 
No.:EP1492571
Date:05.01.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 09.10.2003 takes the place of the publication of the European patent application.
[2005/01]
Search report(s)International search report - published on:EP04.03.2004
ClassificationIPC:A61K51/04, // A61K101:00
[2005/01]
CPC:
A61K51/0459 (EP,US); A61K51/04 (KR); A61K51/0463 (EP,US);
A61P25/00 (EP); A61P25/02 (EP); A61P25/04 (EP);
A61P25/08 (EP); A61P25/14 (EP); A61P25/16 (EP);
A61P25/18 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P25/30 (EP); A61P3/08 (EP);
A61P31/18 (EP); A61P43/00 (EP); A61P9/10 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/01]
Extension statesAL29.10.2004
LT29.10.2004
LV29.10.2004
MK29.10.2004
TitleGerman:RADIOAKTIV MARKIERTE CHINOLIN- UND CHINOLINON-DERIVATE UND IHRE VERWENDUNG ALS METABOTROPE GLUTAMAT-REZEPTOR-LIGANDEN[2005/01]
English:RADIOLABELLED QUINOLINE AND QUINOLINONE DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS[2005/01]
French:DERIVES RADIOMARQUES DE QUINOLINE ET DE QUINOLINONE ET LEUR UTILISATION EN TANT QUE LIGANDS DU RECEPTEUR METABOTROPIQUE DU GLUTAMATE[2005/01]
Entry into regional phase29.10.2004National basic fee paid 
29.10.2004Designation fee(s) paid 
29.10.2004Examination fee paid 
Examination procedure04.09.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
29.10.2004Examination requested  [2005/01]
15.10.2010Despatch of a communication from the examining division (Time limit: M06)
01.03.2011Reply to a communication from the examining division
17.09.2013Despatch of a communication from the examining division (Time limit: M04)
15.01.2014Reply to a communication from the examining division
16.02.2016Despatch of a communication from the examining division (Time limit: M06)
17.08.2016Reply to a communication from the examining division
23.06.2017Communication of intention to grant the patent
04.11.2017Application deemed to be withdrawn, date of legal effect  [2018/20]
21.12.2017Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2018/20]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.10.2010
Fees paidRenewal fee
31.03.2005Renewal fee patent year 03
31.03.2006Renewal fee patent year 04
02.04.2007Renewal fee patent year 05
31.03.2008Renewal fee patent year 06
31.03.2008Renewal fee patent year 07
31.03.2010Renewal fee patent year 08
31.03.2011Renewal fee patent year 09
31.03.2012Renewal fee patent year 10
02.04.2013Renewal fee patent year 11
31.03.2014Renewal fee patent year 12
31.03.2015Renewal fee patent year 13
31.03.2016Renewal fee patent year 14
31.03.2017Renewal fee patent year 15
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Cited inInternational search[Y]JP2000169450  ;
 [Y]WO9427605  (OREGON STATE [US], et al) [Y] 1-20 * example - *;
 [Y]WO9605818  (NPS PHARMA INC [US]) [Y] 1-20* example 3 *;
 [Y]WO9903822  (UNIV GEORGETOWN [US], et al) [Y] 1-20 * example - * * claim - *;
 [DY]WO9926927  (NPS PHARMA INC [US], et al) [DY] 1-20 * example - * * claim - *;
 [PX]WO0228837  (JANSSEN PHARMACEUTICA NV [BE], et al) [PX] 1-20 * table 10 *;
 [Y]  - PATENT ABSTRACTS OF JAPAN, (20001013), vol. 2000, no. 09, & JP2000169450 A 20000620 (KYORIN PHARMACEUT CO LTD) [Y] 1-20 * abstract *
 [Y]  - STONE T W, "Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, (200004), vol. 21, no. 4, ISSN 0165-6147, pages 149 - 154, XP004196017 [Y] 1-20 * abstract * * figures 1,2 *

DOI:   http://dx.doi.org/10.1016/S0165-6147(00)01451-6
 [Y]  - SING-YUEN S ET AL, "3-Hydroxy-quinolin-2-ones: inhibitors of [H]-glycine binding to the site associated with the NMDA receptor", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, (19960305), vol. 6, no. 5, ISSN 0960-894X, pages 499 - 504, XP004135016 [Y] 1-20 * abstract * * page 501 * * page 502; table . *

DOI:   http://dx.doi.org/10.1016/0960-894X(96)00031-5
 [Y]  - DABHI T P ET AL, "POTENTIAL ANTIMICROBIAL AGENTS: SYNTHESIS OF N,N-DIARYL/N,N-DIALKYL/N-ARYL-N-ALKYL-(2-ARYL/STYRYL-6-ACETYLQUINOLIN -4-YL)-FORMAMIDES", INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, R.S. VERMA, LUCKNOW, IN, (199210), vol. 2, no. 2, ISSN 0971-1627, pages 137 - 138, XP000943434 [Y] 1-20 * the whole document *
 [Y]  - BHATT D J ET AL, "STUDIES ON CHALCONES: PREPARATION AND ANTIMICROBIAL ACTIVITY OF 2-ARYL-4-CARBOXY-6-ACETYLQUINOLINE AND 2-ARYL-4-CARBOXY-6- BENZALACETOQUINOLINES", JOURNAL OF THE INDIAN CHEMICAL SOCIETY, THE INDIAN CHEMICAL SOCIETY, CALCUTTA, IN, (198409), vol. 61, no. 9, ISSN 0019-4522, pages 816 - 818, XP000943275 [Y] 1-20 * the whole document *
 [DY]  - MUTEL VINCENT ET AL, "Characterization of (3H)quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.", JOURNAL OF NEUROCHEMISTRY, (200012), vol. 75, no. 6, ISSN 0022-3042, pages 2590 - 2601, XP002226239 [DY] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1046/j.1471-4159.2000.0752590.x
 [Y]  - PENG C T ET AL, "AN EVALUATION OF DIFFERENT METHODS FOR TRITIUM LABELLING", FUSION TECHNOLOGY, AMERICAN NUCLEAR SOCIETY. LAGRANGE PARK, ILLINOIS, US, (19920301), vol. 21, no. 2 PT 2, ISSN 0748-1896, pages 307 - 311, XP000271846 [Y] 1-20 * the whole document *
 [Y]  - BRUNDISH ET AL, "Tritium labeling by selective debromination", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, SUSSEX, GB, (1988), vol. 25, no. 12, ISSN 0362-4803, pages 1361 - 1369, XP002079113 [Y] 1-20 * the whole document *
by applicant   - PATENT ABSTRACTS OF JAPAN, (2000), vol. 2000, no. 9
    - TRENDS IN PHARMACOLOGICAL SCIENCES, (2000), vol. 21, no. 4, pages 149 - 154
    - BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (1996), vol. 6, no. 5, pages 499 - 504
    - JOURNAL OF NEUROCHEMISTRY, (2000), vol. 75, no. 6, pages 2590 - 2601
    - FUSION TECHNOLOGY, (1992), vol. 21, no. 2, pages 307 - 311
    - JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, (1988), vol. 25, no. 12, pages 1361 - 1369
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.