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Extract from the Register of European Patents

EP About this file: EP1539221

EP1539221 - TRANSFERRIN FUSION PROTEIN LIBRARIES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.10.2010
Database last updated on 31.08.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For all designated states
Biorexis Pharmaceutical Corporation
235 East 42nd Street
New York, NY 10017-5755 / US
[2008/26]
Former [2007/51]For all designated states
Biorexis Pharmaceutical Corporation
3400 Horizon Drive
King of Prussia, PA 19406-2675 / US
Former [2007/07]For all designated states
BioRexis Technology, Inc.
103 Foulk Road, Suite 202
Wilmington, DE 19803 / US
Former [2005/24]For all designated states
Biorexis Pharmaceutical Corporation
3400 Horizon Drive
King of Prussia, PA 19406-2675 / US
Inventor(s)01 / PRIOR, Christopher, P.
c/o Biorexis Pharmaceutical Corporation 235 East 42nd Street
New York, NY 10017-5755 / US
02 / TURNER, Andrew, J.
203 Alumni Avenue
Durham NG 27713 / US
03 / SADEGHI, Homayoun
5708 Martin Hills Lane
Hillsborough, NC 27278 / US
 [2009/52]
Former [2005/24]01 / PRIOR, Christopher, P.
3400 Horizon Drive
King of Prussia, PA 19406-2675 / US
02 / TURNER, Andrew, J.
3400 Horizon Drive
King of Prussia, PA 19406-2675 / US
03 / SADEGHI, Homayoun
3400 Horizon Drive
King of Prussia, PA 19406-2675 / US
Representative(s)Cripps, Joanna Elizabeth, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2005/24]Cripps, Joanna Elizabeth, et al
Mewburn Ellis LLP York House 23 Kingsway
London WC2B 6HP / GB
Application number, filing date03751903.028.08.2003
[2005/24]
WO2003US26779
Priority number, dateUS20020406977P30.08.2002         Original published format: US 406977 P
US2003038406010.03.2003         Original published format: US 384060
US20030485404P09.07.2003         Original published format: US 485404 P
[2005/24]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004020588
Date:11.03.2004
Language:EN
[2004/11]
Type: A2 Application without search report 
No.:EP1539221
Date:15.06.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 11.03.2004 takes the place of the publication of the European patent application.
[2005/24]
Type: B1 Patent specification 
No.:EP1539221
Date:23.12.2009
Language:EN
[2009/52]
Search report(s)International search report - published on:US21.04.2005
(Supplementary) European search report - dispatched on:EP03.07.2007
ClassificationIPC:A61K38/40, A61K38/16, A61K38/41, C07K14/79
[2007/31]
CPC:
C12N15/1037 (EP); C12N15/1044 (EP); C12N15/62 (EP);
C07K2319/31 (EP); C07K2319/75 (EP)
Former IPC [2005/24]A61K38/40, C07K14/79, C07K16/46
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/24]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:TRANSFERRIN-FUSIONSPROTEINBIBLIOTHEKEN[2005/24]
English:TRANSFERRIN FUSION PROTEIN LIBRARIES[2005/24]
French:BANQUES DE PROTEINES DE FUSION DE LA TRANSFERINE[2005/24]
Entry into regional phase21.03.2005National basic fee paid 
21.03.2005Search fee paid 
21.03.2005Designation fee(s) paid 
21.03.2005Examination fee paid 
Examination procedure21.03.2005Examination requested  [2005/24]
01.10.2007Despatch of a communication from the examining division (Time limit: M06)
21.05.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
10.07.2008Reply to a communication from the examining division
03.07.2009Communication of intention to grant the patent
28.09.2009Fee for grant paid
28.09.2009Fee for publishing/printing paid
Opposition(s)24.09.2010No opposition filed within time limit [2010/48]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
10.07.2008Request for further processing filed
10.07.2008Full payment received (date of receipt of payment)
Fees paidRenewal fee
24.08.2005Renewal fee patent year 03
14.08.2006Renewal fee patent year 04
22.08.2007Renewal fee patent year 05
21.08.2008Renewal fee patent year 06
20.08.2009Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT23.12.2009
BE23.12.2009
CY23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
SK23.12.2009
TR23.12.2009
BG23.03.2010
GR24.03.2010
PT23.04.2010
HU24.06.2010
LU28.08.2010
CH31.08.2010
LI31.08.2010
MC31.08.2010
[2012/47]
Former [2012/44]AT23.12.2009
BE23.12.2009
CY23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
SK23.12.2009
BG23.03.2010
GR24.03.2010
PT23.04.2010
HU24.06.2010
LU28.08.2010
CH31.08.2010
LI31.08.2010
MC31.08.2010
Former [2012/42]AT23.12.2009
BE23.12.2009
CY23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
SK23.12.2009
BG23.03.2010
GR24.03.2010
PT23.04.2010
HU24.06.2010
CH31.08.2010
LI31.08.2010
MC31.08.2010
Former [2011/20]AT23.12.2009
BE23.12.2009
CY23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
SK23.12.2009
BG23.03.2010
GR24.03.2010
PT23.04.2010
CH31.08.2010
LI31.08.2010
MC31.08.2010
Former [2011/15]AT23.12.2009
BE23.12.2009
CY23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
SK23.12.2009
BG23.03.2010
GR24.03.2010
PT23.04.2010
MC31.08.2010
Former [2010/48]AT23.12.2009
BE23.12.2009
CY23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
SK23.12.2009
BG23.03.2010
GR24.03.2010
PT23.04.2010
Former [2010/39]AT23.12.2009
BE23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
SK23.12.2009
BG23.03.2010
PT23.04.2010
Former [2010/37]AT23.12.2009
BE23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
BG23.03.2010
PT23.04.2010
Former [2010/36]AT23.12.2009
CZ23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
BG23.03.2010
PT23.04.2010
Former [2010/35]AT23.12.2009
EE23.12.2009
RO23.12.2009
SI23.12.2009
BG23.03.2010
PT23.04.2010
Former [2010/30]AT23.12.2009
SI23.12.2009
Former [2010/23]SI23.12.2009
Documents cited:Search[PX]WO03020746  (BIOREXIS PHARMACEUTICAL CORP [US], et al) [PX] 1-54 * page 20; example -; claim - *;
 [A]  - PARK E ET AL, "Production and characterization of fusion proteins containing transferrin and nerve growth factor", JOURNAL OF DRUG TARGETING, HARWOOD ACADEMIC PUBLISHERS GMBH, DE, (1998), vol. 6, no. 1, ISSN 1061-186X, pages 53 - 64, XP002960815 [A] * abstract *
 [A]  - PARISE F ET AL, "Construction and in vitro functional evaluation of a low-density lipoprotein receptor/transferrin fusion protein as a therapeutic tool for familial hypercholesterolemia", HUMAN GENE THERAPY, MARY ANN LIEBERT, NEW YORK ,NY, US, (19990501), vol. 10, no. 7, ISSN 1043-0342, pages 1219 - 1228, XP009057500 [A] * abstract *

DOI:   http://dx.doi.org/10.1089/10430349950018201
International search[Y]US5026651  (BOWMAN BARBARA H [US], et al);
 [Y]US5986067  (FUNK WALTER D [US], et al);
 [X]US2003221201  (PRIOR CHRISTOPHER P [US], et al);
 [X]  - SHIN ET AL., "Transferin-antibody fusion proteins are effective in brain targeting", PROC. NATL. ACAD. SCI. USA, (199503), vol. 92, pages 2820 - 2824, XP001126925

DOI:   http://dx.doi.org/10.1073/pnas.92.7.2820
 [X]  - ALI ET AL., "Trasnferin trojan horses as a rational approach for the biological delivery of therapeutic peptide domains", J. BIOL. CHEM., (19990820), vol. 274, no. 24, pages 24066 - 24073, XP002985527

DOI:   http://dx.doi.org/10.1074/jbc.274.34.24066
 [Y]  - GALLOP ET AL., "Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries", J. MED. CHEM., (19940429), vol. 37, no. 9, pages 1234 - 1251, XP002911078
 [A]  - MACGILLIVRAY ET AL., "The primary structure of human serum transferin", J. BIOL. CHEM., (19830325), vol. 258, no. 6, pages 3543 - 3553, XP002985528
ExaminationUS5672683
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.