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Extract from the Register of European Patents

EP About this file: EP1513932

EP1513932 - TRANSGENIC CLAWED FROG EMBRYOS AND USE THEREOF AS DETECTORS OF ENDOCRINE DISRUPTERS IN THE ENVIRONMENT [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.05.2016
Database last updated on 07.10.2024
Most recent event   Tooltip17.08.2018Lapse of the patent in a contracting state
New state(s): BG		published on 19.09.2018  [2018/38]
Applicant(s)For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-
3, rue Michel-Ange
75016 Paris / FR
For all designated states
MUSEUM NATIONAL D'HISTOIRE NATURELLE
57, rue Cuvier
75231 Paris Cedex 05 / FR
[2015/28]
Former [2006/30]For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
3, rue Michel Ange
75016 Paris / FR
For all designated states
MUSEUM NATIONAL D'HISTOIRE NATURELLE
57, rue Cuvier
75231 Paris Cedex 05 / FR
Former [2006/28]For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
3, rue Michel Ange
75016 Paris / FR
For all designated states
MUSEUM NATIONAL D'HISTOIRE NATURELLE
43, Rue Cuvier
75231 Paris Cedex 05 / FR
Former [2005/11]For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
3, rue Michel Ange
75016 Paris / FR
Inventor(s)01 / DEMENEIX, Barbara
69, rue Broca
F-75013 Paris / FR
02 / TURQUE, Nathalie
106, rue de l'Université
F-75007 Paris / FR
 [2005/11]
Representative(s)Regimbeau
20, rue de Chazelles
75847 Paris Cedex 17 / FR
[2012/49]
Former [2005/11]Ahner, Francis, et al
Cabinet Régimbeau 20, rue de Chazelles
75847 Paris cedex 17 / FR
Application number, filing date03756011.727.05.2003
[2005/11]
WO2003FR01598
Priority number, dateFR2002000666930.05.2002         Original published format: FR 0206669
[2005/11]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO03102176
Date:11.12.2003
Language:FR
[2003/50]
Type: A1 Application with search report 
No.:EP1513932
Date:16.03.2005
Language:FR
The application published by WIPO in one of the EPO official languages on 11.12.2003 takes the place of the publication of the European patent application.
[2005/11]
Type: B1 Patent specification 
No.:EP1513932
Date:08.07.2015
Language:FR
[2015/28]
Search report(s)International search report - published on:EP11.12.2003
ClassificationIPC:C12N15/00, A01K67/027, C12N15/85, G01N33/50, C12N5/10
[2005/11]
CPC:
C12N15/8509 (EP,US); A01K67/0275 (EP,US); G01N33/5014 (EP,US);
A01K2217/05 (EP,US); A01K2227/50 (EP,US); A01K2267/0393 (EP,US);
G01N2333/4606 (EP,US); G01N2500/10 (EP,US); G01N2520/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2015/28]
Former [2005/11]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:TRANSGENE XENOPUS EMBRYOS ZUR ERKENNUNG VON ENDOKRINEN UMWELTSTÖRUNGEN[2005/11]
English:TRANSGENIC CLAWED FROG EMBRYOS AND USE THEREOF AS DETECTORS OF ENDOCRINE DISRUPTERS IN THE ENVIRONMENT[2005/11]
French:EMBRYONS TRANSGÉNIQUES DE XÉNOPE ET LEURS UTILISATIONS POUR LA DÉTECTION DE PERTURBATEURS ENDOCRINIENS DANS L'ENVIRONNEMENT[2015/01]
Former [2005/11]EMBRYONS TRANSGENIQUES DE XENOPE ET LEURS UTILISATIONS POUR LA DETECTION DE PERTURBATEURS ENDOCRINIENS DAN L ENVIRONNEMENT
Entry into regional phase06.12.2004National basic fee paid 
06.12.2004Designation fee(s) paid 
06.12.2004Examination fee paid 
Examination procedure29.12.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
06.12.2004Examination requested  [2005/11]
21.01.2008Despatch of a communication from the examining division (Time limit: M06)
07.07.2008Reply to a communication from the examining division
10.08.2009Despatch of a communication from the examining division (Time limit: M06)
18.12.2009Reply to a communication from the examining division
24.01.2011Despatch of a communication from the examining division (Time limit: M06)
05.07.2011Reply to a communication from the examining division
30.11.2012Despatch of a communication from the examining division (Time limit: M06)
29.05.2013Reply to a communication from the examining division
21.11.2014Cancellation of oral proceeding that was planned for 25.11.2014
25.11.2014Date of oral proceedings (cancelled)
21.01.2015Communication of intention to grant the patent
21.05.2015Fee for grant paid
21.05.2015Fee for publishing/printing paid
21.05.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.01.2008
Opposition(s)11.04.2016No opposition filed within time limit [2016/24]
Fees paidRenewal fee
06.12.2004Renewal fee patent year 03
30.05.2006Renewal fee patent year 04
29.05.2007Renewal fee patent year 05
29.05.2008Renewal fee patent year 06
25.05.2009Renewal fee patent year 07
28.05.2010Renewal fee patent year 08
30.05.2011Renewal fee patent year 09
28.05.2012Renewal fee patent year 10
24.06.2013Renewal fee patent year 11
26.05.2014Renewal fee patent year 12
28.05.2015Renewal fee patent year 13
Penalty fee
Additional fee for renewal fee
31.05.201311   M06   Fee paid on   24.06.2013
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.05.2003
AT08.07.2015
BG08.07.2015
CY08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
NL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
TR08.07.2015
GR09.10.2015
PT09.11.2015
[2018/38]
Former [2018/29]HU27.05.2003
AT08.07.2015
CY08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
NL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
TR08.07.2015
GR09.10.2015
PT09.11.2015
Former [2018/28]HU27.05.2003
AT08.07.2015
CY08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
MC08.07.2015
NL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
GR09.10.2015
PT09.11.2015
Former [2017/40]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
NL08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/36]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
RO08.07.2015
SE08.07.2015
SI08.07.2015
SK08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/23]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
RO08.07.2015
SE08.07.2015
SK08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/22]AT08.07.2015
CZ08.07.2015
DK08.07.2015
EE08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/21]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
IT08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/20]AT08.07.2015
DK08.07.2015
ES08.07.2015
FI08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/11]AT08.07.2015
ES08.07.2015
FI08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/10]ES08.07.2015
FI08.07.2015
SE08.07.2015
GR09.10.2015
PT09.11.2015
Former [2016/09]FI08.07.2015
GR09.10.2015
Cited inInternational search[Y]US5571722  (ROSSON REINHARDT A [US]) [Y] 1-33 * the whole document *;
 [Y]US5612184  (ROSSON REINHARDT A [US]) [Y] 33 * the whole document *;
 [Y]WO9303179  (BIO TECH RESOURCES [US]) [Y] 22-27 * the whole document *;
 [Y]EP1130086  (DEUTSCHES KREBSFORSCH [DE], et al) [Y] 1-27 * the whole document *;
 [A]EP1180684  (UNIV HIROSHIMA PRESIDENT [JP]) [A] 22,24,27 * the whole document *;
 [A]WO9830715  (CALIFORNIA INST OF TECHN [US], et al) [A] 1 * the whole document *;
 [A]US5094944  (HAYES KENNETH R [US]) [A] 1,22 * the whole document *;
 [A]WO9828971  (UNIV TECHNOLOGY CORP [US], et al) [A] 1 * the whole document *;
 [A]WO0188115  (FOND JEAN DAUSSET CEPH [FR], et al) [A] 1 * the whole document *;
 [XY]  - OOFUSA K, TOOI O, KASHIWAGI A, KASHIWAGI K, KONDO Y, WATANABE Y, SAWADA T, FUJIKAWA K, YOSHIZATO K., "Expression of thyroid hormone receptor betaA gene assayed by transgenic Xenopus laevis carrying its promoter sequences.", MOL CELL ENDOCRINOL, (20010705), vol. 181, no. 1-2, pages 97 - 110, XP002234275 [X] 1-6,11,13-18,24,27 * the whole document * [Y] 1-33

DOI:   http://dx.doi.org/10.1016/S0303-7207(01)00529-9
 [XY]  - DE LUZE A, SACHS L, DEMENEIX B., "Thyroid hormone-dependent transcriptional regulation of exogenous genes transferred into Xenopus tadpole muscle in vivo.", PROC NATL ACAD SCI U S A., (199308), vol. 90, no. 15, pages 7322 - 7326, XP002253795 [X] 1-5,8,9,11,13-19 * the whole document * [Y] 11-33

DOI:   http://dx.doi.org/10.1073/pnas.90.15.7322
 [PXY]  - SACHS LM, JONES PL, HAVIS E, ROUSE N, DEMENEIX BA, SHI YB., "Nuclear receptor corepressor recruitment by unliganded thyroid hormone receptor in gene repression during Xenopus laevis development.", MOL CELL BIOL., (200212), vol. 22, no. 24, pages 8527 - 8538, XP002253796 [PX] 1-5,8,9,11,13-19 * the whole document * [Y] 11-33

DOI:   http://dx.doi.org/10.1128/MCB.22.24.8527-8538.2002
Examination   - ZOELLER R THOMAS ET AL, "Thyroid hormone, brain development, and the environment", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (200206), Database accession no. PREV200200399959
    - FURLOW J DAVID ET AL, "In vitro and in vivo analysis of the regulation of a transcription factor gene by thyroid hormone during Xenopus laevis metamorphosis", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (199912), Database accession no. PREV200000049749
    - FOSTER ROSEMARY ET AL, "Multiple SW16-dependent cis-acting elements control SW14 transcription through the cell cycle", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1993), Database accession no. PREV199396040121
    - FURLOW, J.D. AND BROWN, D.D., "Xenopus laevis TH/bZIP B gene promoter region, and exon 1", GENBANK, Database accession no. AF192492
    - ERICA GIES, "Unhealthy Glow: Fluorescent Tadpoles Expose Chemical Contamination", SCIENTIFIC AMERICAN, (20130207), URL: http://www.scientificamerican.com/article/transgenic-tadpole-glows-to-reveal-chemical-contamination/
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.