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Extract from the Register of European Patents

EP About this file: EP1546350

EP1546350 - CELLS OVEREXPRESSING LIPOYL-PROTEIN LIGASE B-GENE FOR FERMENTATIVE PRODUCTION OF R-ALPHA-LIPONIC ACID [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.09.2006
Database last updated on 30.09.2024
Most recent event   Tooltip06.11.2009Change - representativepublished on 09.12.2009  [2009/50]
Applicant(s)For all designated states
Consortium für elektrochemische Industrie GmbH
Zielstattstrasse 20
81379 München / DE
[2005/26]
Inventor(s)01 / DASSLER, Tobias
Himalajastrasse 14
81825 München / DE
 [2005/26]
Representative(s)Potten, Holger, et al
Wacker Chemie AG
Zentralbereich Patente, Marken und Lizenzen
Hanns-Seidel-Platz 4
81737 München / DE
[N/P]
Former [2009/50]Potten, Holger, et al
Wacker Chemie AG Zentralbereich Patente, Marken und Lizenzen Hanns-Seidel-Platz 4
81737 München / DE
Former [2005/26]Potten, Holger, et al
Wacker-Chemie GmbH Zentralbereich PML, Hanns-Seidel-Platz 4
81737 München / DE
Application number, filing date03810946.825.09.2003
[2005/26]
WO2003EP10687
Priority number, dateDE200214599302.10.2002         Original published format: DE 10245993
[2005/26]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report
No.:WO2004044211
Date:27.05.2004
Language:DE
[2004/22]
Type: A1 Application with search report 
No.:EP1546350
Date:29.06.2005
Language:DE
The application published by WIPO in one of the EPO official languages on 27.05.2004 takes the place of the publication of the European patent application.
[2005/26]
Search report(s)International search report - published on:EP27.05.2004
ClassificationIPC:C12P7/42, C12N15/63, C12N1/21, C07D339/04
[2005/26]
CPC:
C12N9/93 (EP,US); C12N15/63 (EP,US); C12P11/00 (EP,US);
C12P17/00 (EP,US)
Designated contracting statesDE,   FR,   GB,   IT [2006/04]
Former [2005/26]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:ZELLEN DIE, EIN LIPOYL-PROTEIN-LIGASE B-GEN ÖBEREXPRIMIEREN, ZUR FERMENTATIVEN HERSTELLUNG VON R-ALPHA-LIPONSÄURE[2005/27]
English:CELLS OVEREXPRESSING LIPOYL-PROTEIN LIGASE B-GENE FOR FERMENTATIVE PRODUCTION OF R-ALPHA-LIPONIC ACID[2005/26]
French:CELLULES SUREXPRIMANT UN GENE DE LIGASE B DE PROTEINE LIPOYLE PERMETTANT DE PRODUIRE PAR FERMENTATION DE L'ACIDE LIPOIQUE R-ALPHA[2005/26]
Former [2005/26]ZELLEN DIE, EIN LIPOYL-PROTEIN-LIGASE B-GEN BEREXPRIMIEREN, ZUR FERMENTATIVEN HERSTELLUNG VON R-ALPHA-LIPONS URE
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase24.03.2005National basic fee paid 
24.03.2005Designation fee(s) paid 
24.03.2005Examination fee paid 
Examination procedure24.03.2005Examination requested  [2005/26]
10.08.2005Despatch of a communication from the examining division (Time limit: M04)
15.12.2005Reply to a communication from the examining division
25.01.2006Despatch of a communication from the examining division (Time limit: M02)
05.04.2006Application deemed to be withdrawn, date of legal effect  [2006/42]
11.05.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2006/42]
Fees paidRenewal fee
21.09.2005Renewal fee patent year 03
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[X]DE10042739  (DEGUSSA [DE]) [X] 8 * example 2; claims 1-5 *;
 [XD]  - REED K E ET AL, "LIPOIC ACID METABOLISM IN ESCHERICHIA COLI: SEQUENCING AND FUNCTIONAL CHARACTERIZATION OF LIPA AND LIPB GENES", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, (199303), vol. 175, no. 5, ISSN 0021-9193, pages 1325 - 1336, XP008025890 [XD] 1-10 * the whole document *
 [XY]  - VAISVILA ROMAS ET AL, "The LipB protein is a negative regulator of dam gene expression in Escherichia coli", BIOCHIMICA ET BIOPHYSICA ACTA, (20001115), vol. 1494, no. 1-2, ISSN 0006-3002, pages 43 - 53, XP004275790 [X] 1-10 * the whole document * [Y] 11-13

DOI:   http://dx.doi.org/10.1016/S0167-4781(00)00209-8
 [X]  - JORDAN SEAN W ET AL, "A new metabolic link: The acyl carrier protein of lipid synthesis donates lipoic acid to the pyruvate dehydrogenase complex in Escherichia coli and mitochondria", JOURNAL OF BIOLOGICAL CHEMISTRY, (1997), vol. 272, no. 29, ISSN 0021-9258, pages 17903 - 17906, XP002268661 [X] 1-10 * page 17905, column L, paragraph 2 *

DOI:   http://dx.doi.org/10.1074/jbc.272.29.17903
 [X]  - MORRIS TIMOTHY W ET AL, "Lipoic Acid Metabolism in Escherichia coli: The lplA and lipB Genes Define Redundant Pathways for Ligation of Lipoyl Groups to Apoprotein", JOURNAL OF BACTERIOLOGY, (1995), vol. 177, no. 1, ISSN 0021-9193, pages 1 - 10, XP002268660 [X] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1002/path.1711770102
 [X]  - YASUNO R ET AL, "Biosynthesis of lipoic acid in arabidopsis: cloning and characterization of the cDNA for lipoic acid synthase", PLANT PHYSIOLOGY, AMERICAN SOCIETY OF PLANT PHYSIOLOGISTS, ROCKVILLE, MD, US, (1998), vol. 118, ISSN 0032-0889, pages 935 - 943, XP002961224 [X] 8 * the whole document *

DOI:   http://dx.doi.org/10.1104/pp.118.3.935
 [X]  - CHEN X J, "Cloning and characterization of the lipoyl-protein ligase gene LIPB from the yeast Kluyveromyces lactis: Synergistic respiratory deficiency due to mutations in LIPB and mitochondrial F-1-ATPase subunits", MOLECULAR AND GENERAL GENETICS, (1997), vol. 255, no. 3, ISSN 0026-8925, pages 341 - 349, XP002268663 [X] 8 * the whole document *

DOI:   http://dx.doi.org/10.1007/s004380050505
 [Y]  - MCFARLAN SARA ET AL, "Production of alpha-lipoic acid by a recombinant organism", ABSTRACTS OF PAPERS AMERICAN CHEMICAL SOCIETY, 224th National Meeting of the American Chemical Society;Boston, MA, USA; August 18-22, 2002, (20020818), vol. 224, no. 1-2, ISSN 0065-7727, page BIOT 220, XP008027301 [Y] 11-13 * the whole document *
 [PX]  - JORDAN SEAN W ET AL, "The Escherichia coli lipB gene encodes lipoyl (octanoyl)-acyl carrier protein:protein transferase.", JOURNAL OF BACTERIOLOGY, (200303), vol. 185, no. 5, ISSN 0021-9193, pages 1582 - 1589, XP002268662 [PX] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1128/JB.185.5.1582-1589.2003
 [AD]  - GOPALAN A S ET AL, "STEREOCHEMICAL CONTROL OF YEAST REDUCTIONS: SYNTHESIS OF R-(+)-ALPHA-LIPOIC ACID", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (1989), vol. 30, no. 42, ISSN 0040-4039, pages 5705 - 5708, XP001018157 [AD] * the whole document *

DOI:   http://dx.doi.org/10.1016/S0040-4039(00)76176-4
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.