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EP1566383

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Extract from the Register of European Patents

EP About this file: EP1566383

EP1566383 - Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 20.10.2006 Database last updated on 08.10.2024
Most recent event Tooltip	20.10.2006	Application deemed to be withdrawn	published on 22.11.2006 [2006/47]
Applicant(s)	For all designated states Lonza AG Münchensteinerstrasse 38 4052 Basel / CH
	[2005/34]
Inventor(s)	01 / Michel, Dominique Rue du Stade 22 3960 Sierre / CH
	[2005/34]
Application number, filing date	04003809.3	19.02.2004
	[2005/34]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	EP1566383
	Date:	24.08.2005
	Language:	EN
	[2005/34]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	31.08.2004
Classification	IPC:	C07D333/20, C07D333/22, C07C213/00, C07B53/00	[2005/34]
	CPC:	C07D333/22 (EP); C07D333/20 (EP); C07B2200/07 (EP)
Designated contracting states	(deleted) [2006/20]
Former [2005/34]	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, RO, SE, SI, SK, TR
Title	German:	Verfahren zur Herstellung von enantiomerenreinen 1-substituierten 3-Aminoalkoholen	[2005/34]
	English:	Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols	[2005/34]
	French:	Procédé de préparation des enantiomers pures des dérivés de 3-aminoalcools substitués	[2005/34]
Examination procedure	27.09.2005	Application deemed to be withdrawn, date of legal effect [2006/47]
	21.06.2006	Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time [2006/47]
Fees paid	Penalty fee
	Penalty fee Rule 85a EPC 1973
	04.04.2006	AT M01 Not yet paid
	04.04.2006	BE M01 Not yet paid
	04.04.2006	BG M01 Not yet paid
	04.04.2006	CH M01 Not yet paid
	04.04.2006	CY M01 Not yet paid
	04.04.2006	CZ M01 Not yet paid
	04.04.2006	DE M01 Not yet paid
	04.04.2006	DK M01 Not yet paid
	04.04.2006	EE M01 Not yet paid
	04.04.2006	ES M01 Not yet paid
	04.04.2006	FI M01 Not yet paid
	04.04.2006	FR M01 Not yet paid
	04.04.2006	GB M01 Not yet paid
	04.04.2006	GR M01 Not yet paid
	04.04.2006	HU M01 Not yet paid
	04.04.2006	IE M01 Not yet paid
	04.04.2006	IT M01 Not yet paid
	04.04.2006	LU M01 Not yet paid
	04.04.2006	MC M01 Not yet paid
	04.04.2006	NL M01 Not yet paid
	04.04.2006	PT M01 Not yet paid
	04.04.2006	RO M01 Not yet paid
	04.04.2006	SE M01 Not yet paid
	04.04.2006	SI M01 Not yet paid
	04.04.2006	SK M01 Not yet paid
	04.04.2006	TR M01 Not yet paid
	Penalty fee Rule 85b EPC 1973
	04.04.2006	M01 Not yet paid
	Additional fee for renewal fee
	28.02.2006	03 M06 Not yet paid
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	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[Y]JPH0570412 ;
		[Y]EP0457559 (LILLY CO ELI [US]) [Y] 1-12 * page 5, paragraph 1; examples 1,4; claims 1,6 * * page 3, lines 16-19 *;
		[X]US6008412 (RATZ ANDREW MICHAEL [US]) [X] 12 * column 2; examples 1-3,7,8,10; claims 3,4,7,8 *;
		[X]WO03070720 (DEGUSSA [DE], et al) [X] 12 * Scheme 1; page 10, line 28 - page 13, line 13; examples 5,8-10 *;
		[A]WO2004005239 (LONZA AG [CH], et al) [A] 12 * page 6, lines 23-30; examples 9,10; claims 1,5,10,11 * * page 4, line 8 - page 5, line 9 *;
		[A]WO2004005307 (LONZA AG [CH], et al) [A] 12* examples 1,2; claims 1,13-16 *;
		[X] - BECKER H G O ET AL, "Eine einfache Synthese von sekundären Mannich-Basen", WISSENSCHAFTLICHE ZEITSCHRIFT DER TECHNISCHEN HOCHSCHULE FÜR CHEMIE, (1969), vol. 11, no. 1, pages 38 - 41, XP009034925 [X] 8 * Formula 2a on page 38 *
		[X] - SAKAI, KENICHI ET AL, "Resolution of 3-(methylamino)-1-(2-thienyl)propan-1-ol, a new key intermediate for duloxetine, with (S)-mandelic acid", TETRAHEDRON: ASYMMETRY , 14(12), 1631-1636 CODEN: TASYE3; ISSN: 0957-4166, (2003), XP002293165 [X] 12 * page 1632, column 1, paragraph 1; figure 1; tables 1-4 * DOI: http://dx.doi.org/10.1016/S0957-4166(03)00315-X
		[X] - ROBERTSON D W ET AL, ABSOLUTE CONFIGURATIONS AND PHARMACOLOGICAL ACTIVITIES OF THE OPTICAL ISOMERS OF FLUOXETINE, A SELECTIVE SEROTONIN-UPTAKE INHIBITOR, JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, PAGE(S) 1412-1417, (19880701), ISSN 0022-2623, XP000568845 [X] 12 * Scheme 1 on page 1413; page 1416, column 1, paragraph 6 * DOI: http://dx.doi.org/10.1021/jm00402a027
		[Y] - SAKURABA S ET AL, "EFFICIENT ASYMMETRIC HYDROGENATION OF BETA- AND GAMMA-AMINO KETONE DERIVATIVES LEADING TO PRACTICAL SYNTHESIS OF FLUOXETINE AND EPROZINOL", CHEMICAL AND PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOCIETY OF JAPAN. TOKYO, JP, (1995), vol. 43, no. 5, ISSN 0009-2363, pages 748 - 753, XP001071298 [Y] 1-12 * page 751, column 1, paragraph 5 - column 2, paragraph 1; table 1 *
		[Y] - DATABASE WPI, 0, Derwent World Patents Index, Database accession no. 1993-131254, XP002293166 & JPH0570412 A 19930323 (FUJISAWA PHARM CO LTD) [Y] 1-12 * column A *

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