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Extract from the Register of European Patents

EP About this file: EP1493744

EP1493744 - Tropane analogs and methods for inhibition of monoamine transport [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  01.10.2010
Database last updated on 03.09.2024
Most recent event   Tooltip28.09.2012Lapse of the patent in a contracting state
New state(s): LU		published on 31.10.2012  [2012/44]
Applicant(s)For all designated states
ORGANIX, INC.
65 Cummings Park
Woburn, MA 01801 / US
For all designated states
President and Fellows of Harvard College
17 Quincy Street
Cambridge, MA 02138 / US
For all designated states
Meltzer, Peter C.
8 Rumford Road
Lexington, MA 02173 / US
[N/P]
Former [2009/48]For all designated states
ORGANIX, INC.
65 Cummings Park
Woburn, MA 01801 / US
For all designated states
President and Fellows of Harvard College
17 Quincy Street
Cambridge, MA 02138 / US
For all designated states
Meltzer, Peter C.
8 Rumford Road
Lexington, MA 02173 / US
Former [2005/01]For all designated states
ORGANIX, INC.
65 Cummings Park
Woburn, MA 01801 / US
For all designated states
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
17 Quincy Street
Cambridge Massachusetts 02138 / US
For all designated states
Meltzer, Peter C.
8 Rumford Road
Lexington, MA 02173 / US
Inventor(s)01 / Madras, Bertha K.
32 Montrose Road
Newton MA 02158 / US
02 / Blundell, Paul
26 Squire Road
Winchester MA 01890 / US
03 / Chen, Zhengming
Apartment 7 50, Mill Street
Woburn MA 01801 / US
04 / Meltzer, Peter C.
8 Rumford Road
Lexington MA 02173 / US
 [2005/01]
Representative(s)Hofer, Dorothea, et al
Prüfer & Partner GbR
Patentanwälte
Sohnckestrasse 12
81479 München / DE
[N/P]
Former [2005/01]Hofer, Dorothea, Dipl.-Phys., et al
Prüfer & Partner GbR Patentanwälte Harthauser Strasse 25 d
81545 München / DE
Application number, filing date04018348.510.07.1998
[2005/01]
Priority number, dateUS1997089392111.07.1997         Original published format: US 893921
[2005/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1493744
Date:05.01.2005
Language:EN
[2005/01]
Type: B1 Patent specification 
No.:EP1493744
Date:25.11.2009
Language:EN
[2009/48]
Search report(s)(Supplementary) European search report - dispatched on:EP21.09.2004
ClassificationIPC:C07D451/02, C07D311/00, C07C255/00, C07C69/74, C07C233/00, C07C205/00, C07C49/115, C07C49/105, C07C41/00, C07C33/34, C07D493/08, C07F7/22, A61K31/46, A61K31/35, A61P25/30
[2008/32]
CPC:
C07D451/02 (EP,US); A61K31/18 (EP,US); A61K31/198 (EP,US);
A61K31/405 (EP,US); A61K51/0448 (EP,US); A61P25/00 (EP);
A61P25/30 (EP); A61P43/00 (EP); C07C69/753 (EP,US);
C07D451/06 (EP,US); C07D471/08 (EP,US); C07D493/08 (EP,US);
A61K2123/00 (EP,US); A61K38/00 (EP,US); C07C2602/44 (EP,US) (-)
Former IPC [2005/01]C07D451/02, C07D311/00, C07C255/00, C07C69/74, C07C233/00, C07C205/00, C07C49/115, C07C49/105, C07C41/00, C07C33/34, C07D493/08, C07F7/22, A61K31/46, A61K31/35, A61P25/30, // (C07D451/02, 209:00, 205:00),(C07D493/08, 307:00, 305:00)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2005/01]
TitleGerman:Tropananloga und Methoden zur Hemmung des Transports von Monoaminen[2005/01]
English:Tropane analogs and methods for inhibition of monoamine transport[2005/01]
French:Analogues de tropanes et procédés pour inhiber le transport de monoamines[2005/01]
Examination procedure04.07.2005Examination requested  [2005/42]
08.03.2007Despatch of a communication from the examining division (Time limit: M06)
18.09.2007Reply to a communication from the examining division
04.10.2007Despatch of a communication from the examining division (Time limit: M04)
14.02.2008Reply to a communication from the examining division
21.07.2008Communication of intention to grant the patent
28.11.2008Fee for grant paid
28.11.2008Fee for publishing/printing paid
Parent application(s)   TooltipEP98934396.7  / EP0996619
Opposition(s)26.08.2010No opposition filed within time limit [2010/44]
Fees paidRenewal fee
03.08.2004Renewal fee patent year 03
03.08.2004Renewal fee patent year 04
03.08.2004Renewal fee patent year 05
03.08.2004Renewal fee patent year 06
03.08.2004Renewal fee patent year 07
29.07.2005Renewal fee patent year 08
25.07.2006Renewal fee patent year 09
25.07.2008Renewal fee patent year 11
28.07.2009Renewal fee patent year 12
Penalty fee
Additional fee for renewal fee
31.07.200710   M06   Fee paid on   31.01.2008
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
IT25.11.2009
NL25.11.2009
SE25.11.2009
GR26.02.2010
ES08.03.2010
PT25.03.2010
GB10.07.2010
IE10.07.2010
LU10.07.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
FR02.08.2010
[2012/44]
Former [2011/35]AT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
IT25.11.2009
NL25.11.2009
SE25.11.2009
GR26.02.2010
ES08.03.2010
PT25.03.2010
GB10.07.2010
IE10.07.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
FR02.08.2010
Former [2011/32]AT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
IT25.11.2009
NL25.11.2009
SE25.11.2009
GR26.02.2010
ES08.03.2010
PT25.03.2010
GB10.07.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
FR02.08.2010
Former [2011/20]AT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
IT25.11.2009
NL25.11.2009
SE25.11.2009
GR26.02.2010
ES08.03.2010
PT25.03.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
Former [2011/14]AT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
IT25.11.2009
NL25.11.2009
SE25.11.2009
GR26.02.2010
ES08.03.2010
PT25.03.2010
MC31.07.2010
Former [2011/11]AT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
NL25.11.2009
SE25.11.2009
GR26.02.2010
ES08.03.2010
PT25.03.2010
MC31.07.2010
Former [2010/49]AT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
NL25.11.2009
SE25.11.2009
GR26.02.2010
ES08.03.2010
PT25.03.2010
Former [2010/35]AT25.11.2009
BE25.11.2009
CY25.11.2009
DK25.11.2009
FI25.11.2009
NL25.11.2009
SE25.11.2009
ES08.03.2010
PT25.03.2010
Former [2010/32]AT25.11.2009
BE25.11.2009
CY25.11.2009
FI25.11.2009
NL25.11.2009
SE25.11.2009
ES08.03.2010
PT25.03.2010
Former [2010/31]AT25.11.2009
BE25.11.2009
CY25.11.2009
FI25.11.2009
SE25.11.2009
PT25.03.2010
Former [2010/30]AT25.11.2009
CY25.11.2009
FI25.11.2009
SE25.11.2009
PT25.03.2010
Former [2010/25]CY25.11.2009
FI25.11.2009
SE25.11.2009
PT25.03.2010
Former [2010/22]FI25.11.2009
SE25.11.2009
PT25.03.2010
Documents cited:Search[X]US5276211  (NARULA ANUBHAV P S [US], et al) [X] 1-24 * the whole document *;
 [X]  - BLOUGH B E ET AL, "SYNTHESIS AND TRANSPORTER BINDING PROPERTIES OF 3BETA-(4'-ALKYL-, 4'-ALKENYL-, AND 4'-ALKYNYLPHENYL)NORTROPANE- 2BETA-CARBOXYLIC ACID METHYL ESTERS: SEROTONIN TRANSPORTER SELECTIVE ANALOGS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1996), vol. 39, ISSN 0022-2623, pages 4027 - 4035, XP002914104 [X] 1-24 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm960409s
 [X]  - DAVIES H M L ET AL, "SYNTHESIS OF 3BETA-ARYL-8-AZABICYCLOÚ3.2.1OCTANES WITH HIGH BINDING AFFINITIES AND SELECTIVITIES FOR THE SEROTONIN TRANSPORTER SITE", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1996), vol. 39, ISSN 0022-2623, pages 2554 - 2558, XP002914106 [X] 1-24 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm9600508
 [X]  - SIMONI D ET AL, "METHOXYLATION OF COCAINE REDUCES BINDING AFFINITY AND PRODUCES COMPOUNDS OF DIFFERENTIAL BINDING AND DOPAMINE UPTAKE INHIBITORY ACTIVITY: DISCOVERY OF A WEAK COCAINE ANTAGONIST", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1993), vol. 36, ISSN 0022-2623, pages 3975 - 3977, XP002914111 [X] 1-24 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm00076a028
 [XP]  - MELTZER P C ET AL, "2-CARBOMETHOXY-3-ARYL-8-OXABICYCLOÚ3.2.1OCTANES: POTENT NON-NITROGEN INHIBITORS OF MONOAMINE TRANSPORTERS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (19970815), vol. 40, no. 17, ISSN 0022-2623, pages 2661 - 2673, XP002914112 [XP] 1-24 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm9703045
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.