EP1493744 - Tropane analogs and methods for inhibition of monoamine transport [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 01.10.2010 Database last updated on 03.09.2024 | Most recent event Tooltip | 28.09.2012 | Lapse of the patent in a contracting state New state(s): LU | published on 31.10.2012 [2012/44] | Applicant(s) | For all designated states ORGANIX, INC. 65 Cummings Park Woburn, MA 01801 / US | For all designated states President and Fellows of Harvard College 17 Quincy Street Cambridge, MA 02138 / US | For all designated states Meltzer, Peter C. 8 Rumford Road Lexington, MA 02173 / US | [N/P] |
Former [2009/48] | For all designated states ORGANIX, INC. 65 Cummings Park Woburn, MA 01801 / US | ||
For all designated states President and Fellows of Harvard College 17 Quincy Street Cambridge, MA 02138 / US | |||
For all designated states Meltzer, Peter C. 8 Rumford Road Lexington, MA 02173 / US | |||
Former [2005/01] | For all designated states ORGANIX, INC. 65 Cummings Park Woburn, MA 01801 / US | ||
For all designated states PRESIDENT AND FELLOWS OF HARVARD COLLEGE 17 Quincy Street Cambridge Massachusetts 02138 / US | |||
For all designated states Meltzer, Peter C. 8 Rumford Road Lexington, MA 02173 / US | Inventor(s) | 01 /
Madras, Bertha K. 32 Montrose Road Newton MA 02158 / US | 02 /
Blundell, Paul 26 Squire Road Winchester MA 01890 / US | 03 /
Chen, Zhengming Apartment 7 50, Mill Street Woburn MA 01801 / US | 04 /
Meltzer, Peter C. 8 Rumford Road Lexington MA 02173 / US | [2005/01] | Representative(s) | Hofer, Dorothea, et al Prüfer & Partner GbR Patentanwälte Sohnckestrasse 12 81479 München / DE | [N/P] |
Former [2005/01] | Hofer, Dorothea, Dipl.-Phys., et al Prüfer & Partner GbR Patentanwälte Harthauser Strasse 25 d 81545 München / DE | Application number, filing date | 04018348.5 | 10.07.1998 | [2005/01] | Priority number, date | US19970893921 | 11.07.1997 Original published format: US 893921 | [2005/01] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP1493744 | Date: | 05.01.2005 | Language: | EN | [2005/01] | Type: | B1 Patent specification | No.: | EP1493744 | Date: | 25.11.2009 | Language: | EN | [2009/48] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 21.09.2004 | Classification | IPC: | C07D451/02, C07D311/00, C07C255/00, C07C69/74, C07C233/00, C07C205/00, C07C49/115, C07C49/105, C07C41/00, C07C33/34, C07D493/08, C07F7/22, A61K31/46, A61K31/35, A61P25/30 | [2008/32] | CPC: |
C07D451/02 (EP,US);
A61K31/18 (EP,US);
A61K31/198 (EP,US);
A61K31/405 (EP,US);
A61K51/0448 (EP,US);
A61P25/00 (EP);
A61P25/30 (EP);
A61P43/00 (EP);
C07C69/753 (EP,US);
C07D451/06 (EP,US);
C07D471/08 (EP,US);
C07D493/08 (EP,US);
|
Former IPC [2005/01] | C07D451/02, C07D311/00, C07C255/00, C07C69/74, C07C233/00, C07C205/00, C07C49/115, C07C49/105, C07C41/00, C07C33/34, C07D493/08, C07F7/22, A61K31/46, A61K31/35, A61P25/30, // (C07D451/02, 209:00, 205:00),(C07D493/08, 307:00, 305:00) | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2005/01] | Title | German: | Tropananloga und Methoden zur Hemmung des Transports von Monoaminen | [2005/01] | English: | Tropane analogs and methods for inhibition of monoamine transport | [2005/01] | French: | Analogues de tropanes et procédés pour inhiber le transport de monoamines | [2005/01] | Examination procedure | 04.07.2005 | Examination requested [2005/42] | 08.03.2007 | Despatch of a communication from the examining division (Time limit: M06) | 18.09.2007 | Reply to a communication from the examining division | 04.10.2007 | Despatch of a communication from the examining division (Time limit: M04) | 14.02.2008 | Reply to a communication from the examining division | 21.07.2008 | Communication of intention to grant the patent | 28.11.2008 | Fee for grant paid | 28.11.2008 | Fee for publishing/printing paid | Parent application(s) Tooltip | EP98934396.7 / EP0996619 | Opposition(s) | 26.08.2010 | No opposition filed within time limit [2010/44] | Fees paid | Renewal fee | 03.08.2004 | Renewal fee patent year 03 | 03.08.2004 | Renewal fee patent year 04 | 03.08.2004 | Renewal fee patent year 05 | 03.08.2004 | Renewal fee patent year 06 | 03.08.2004 | Renewal fee patent year 07 | 29.07.2005 | Renewal fee patent year 08 | 25.07.2006 | Renewal fee patent year 09 | 25.07.2008 | Renewal fee patent year 11 | 28.07.2009 | Renewal fee patent year 12 | Penalty fee | Additional fee for renewal fee | 31.07.2007 | 10   M06   Fee paid on   31.01.2008 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 25.11.2009 | BE | 25.11.2009 | CY | 25.11.2009 | DK | 25.11.2009 | FI | 25.11.2009 | IT | 25.11.2009 | NL | 25.11.2009 | SE | 25.11.2009 | GR | 26.02.2010 | ES | 08.03.2010 | PT | 25.03.2010 | GB | 10.07.2010 | IE | 10.07.2010 | LU | 10.07.2010 | CH | 31.07.2010 | LI | 31.07.2010 | MC | 31.07.2010 | FR | 02.08.2010 | [2012/44] |
Former [2011/35] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
DK | 25.11.2009 | ||
FI | 25.11.2009 | ||
IT | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
GR | 26.02.2010 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
GB | 10.07.2010 | ||
IE | 10.07.2010 | ||
CH | 31.07.2010 | ||
LI | 31.07.2010 | ||
MC | 31.07.2010 | ||
FR | 02.08.2010 | ||
Former [2011/32] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
DK | 25.11.2009 | ||
FI | 25.11.2009 | ||
IT | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
GR | 26.02.2010 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
GB | 10.07.2010 | ||
CH | 31.07.2010 | ||
LI | 31.07.2010 | ||
MC | 31.07.2010 | ||
FR | 02.08.2010 | ||
Former [2011/20] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
DK | 25.11.2009 | ||
FI | 25.11.2009 | ||
IT | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
GR | 26.02.2010 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
CH | 31.07.2010 | ||
LI | 31.07.2010 | ||
MC | 31.07.2010 | ||
Former [2011/14] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
DK | 25.11.2009 | ||
FI | 25.11.2009 | ||
IT | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
GR | 26.02.2010 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
MC | 31.07.2010 | ||
Former [2011/11] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
DK | 25.11.2009 | ||
FI | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
GR | 26.02.2010 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
MC | 31.07.2010 | ||
Former [2010/49] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
DK | 25.11.2009 | ||
FI | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
GR | 26.02.2010 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
Former [2010/35] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
DK | 25.11.2009 | ||
FI | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
Former [2010/32] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
FI | 25.11.2009 | ||
NL | 25.11.2009 | ||
SE | 25.11.2009 | ||
ES | 08.03.2010 | ||
PT | 25.03.2010 | ||
Former [2010/31] | AT | 25.11.2009 | |
BE | 25.11.2009 | ||
CY | 25.11.2009 | ||
FI | 25.11.2009 | ||
SE | 25.11.2009 | ||
PT | 25.03.2010 | ||
Former [2010/30] | AT | 25.11.2009 | |
CY | 25.11.2009 | ||
FI | 25.11.2009 | ||
SE | 25.11.2009 | ||
PT | 25.03.2010 | ||
Former [2010/25] | CY | 25.11.2009 | |
FI | 25.11.2009 | ||
SE | 25.11.2009 | ||
PT | 25.03.2010 | ||
Former [2010/22] | FI | 25.11.2009 | |
SE | 25.11.2009 | ||
PT | 25.03.2010 | Documents cited: | Search | [X]US5276211 (NARULA ANUBHAV P S [US], et al) [X] 1-24 * the whole document *; | [X] - BLOUGH B E ET AL, "SYNTHESIS AND TRANSPORTER BINDING PROPERTIES OF 3BETA-(4'-ALKYL-, 4'-ALKENYL-, AND 4'-ALKYNYLPHENYL)NORTROPANE- 2BETA-CARBOXYLIC ACID METHYL ESTERS: SEROTONIN TRANSPORTER SELECTIVE ANALOGS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1996), vol. 39, ISSN 0022-2623, pages 4027 - 4035, XP002914104 [X] 1-24 * the whole document * DOI: http://dx.doi.org/10.1021/jm960409s | [X] - DAVIES H M L ET AL, "SYNTHESIS OF 3BETA-ARYL-8-AZABICYCLOÚ3.2.1OCTANES WITH HIGH BINDING AFFINITIES AND SELECTIVITIES FOR THE SEROTONIN TRANSPORTER SITE", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1996), vol. 39, ISSN 0022-2623, pages 2554 - 2558, XP002914106 [X] 1-24 * the whole document * DOI: http://dx.doi.org/10.1021/jm9600508 | [X] - SIMONI D ET AL, "METHOXYLATION OF COCAINE REDUCES BINDING AFFINITY AND PRODUCES COMPOUNDS OF DIFFERENTIAL BINDING AND DOPAMINE UPTAKE INHIBITORY ACTIVITY: DISCOVERY OF A WEAK COCAINE ANTAGONIST", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1993), vol. 36, ISSN 0022-2623, pages 3975 - 3977, XP002914111 [X] 1-24 * the whole document * DOI: http://dx.doi.org/10.1021/jm00076a028 | [XP] - MELTZER P C ET AL, "2-CARBOMETHOXY-3-ARYL-8-OXABICYCLOÚ3.2.1OCTANES: POTENT NON-NITROGEN INHIBITORS OF MONOAMINE TRANSPORTERS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (19970815), vol. 40, no. 17, ISSN 0022-2623, pages 2661 - 2673, XP002914112 [XP] 1-24 * the whole document * DOI: http://dx.doi.org/10.1021/jm9703045 |