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Extract from the Register of European Patents

EP About this file: EP1475439

EP1475439 - Control of metabolism with compositions of the human 2-oxoglutarate carrier [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  02.05.2008
Database last updated on 19.10.2024
Most recent event   Tooltip02.05.2008Application deemed to be withdrawnpublished on 04.06.2008  [2008/23]
Applicant(s)For all designated states
Genentech, Inc.
1 DNA Way
South San Francisco, CA 94080-4990 / US
[N/P]
Former [2004/46]For all designated states
Genentech, Inc.
1 DNA Way
South San Francisco, CA 94080-4990 / US
Inventor(s)01 / Adams, Sean
2308 Casa Bona Avenue
Belmont, CA 94002 / US
02 / Yu, Xing Xian
117 W. Hillsdale Boulevard, Apt. Nr. E
San Mateo, CA 94403 / US
 [2004/46]
Representative(s)MacLean, Martin Robert, et al
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2004/46]MacLean, Martin Robert, et al
Mathys & Squire 100 Gray's Inn Road
London WC1X 8AL / GB
Application number, filing date04019057.122.06.2001
[2004/46]
Priority number, dateUS20000213307P22.06.2000         Original published format: US 213307 P
[2004/46]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1475439
Date:10.11.2004
Language:EN
[2004/46]
Type: A3 Search report 
No.:EP1475439
Date:05.01.2005
[2005/01]
Search report(s)(Supplementary) European search report - dispatched on:EP23.11.2004
ClassificationIPC:C12N15/12, C12N5/10, C07K14/47, C12Q1/68, G01N33/50, G01N27/26, A61K31/713, // A61P3/00, A61P3/04
[2004/46]
CPC:
G01N33/5079 (EP); A61P3/00 (EP); A61P3/04 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/46]
TitleGerman:Metabolismuskontrolle mittels Zusamensetzungen des humanen 2-oxoglutarat-Trägers[2004/46]
English:Control of metabolism with compositions of the human 2-oxoglutarate carrier[2004/46]
French:Contrôle du métabolisme avec des compositions contenant le transporteur de 2-oxoglutarate[2004/46]
Examination procedure11.08.2004Examination requested  [2004/46]
10.07.2007Despatch of a communication from the examining division (Time limit: M04)
21.11.2007Application deemed to be withdrawn, date of legal effect  [2008/23]
18.01.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/23]
Parent application(s)   TooltipEP01950401.8  / EP1294881
Fees paidRenewal fee
11.08.2004Renewal fee patent year 03
11.08.2004Renewal fee patent year 04
14.06.2005Renewal fee patent year 05
27.03.2006Renewal fee patent year 06
14.06.2007Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO9964458  (UNIV BOSTON [US]) [A] 1-26 * See abstract, claim 6 and Example 3. *;
 [X]  - VIDAL-PUIG ANTONIO J ET AL, "Energy metabolism in uncoupling protein 3 gene knockout mice", JOURNAL OF BIOLOGICAL CHEMISTRY, (20000526), vol. 275, no. 21, ISSN 0021-9258, pages 16258 - 16266, XP002303864 [X] 23-25,27-29 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.M910179199
 [A]  - HUIZING M ET AL, "HUMAN MITOCHONDRIAL TRANSMEMBRANE METABOLITE CARRIERS: TISSUE DISTRIBUTION AND ITS IMPLICATION FOR MITOCHONDRIAL DISORDERS", JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, PLENUM PUBLISHING, NEW YORK, NY, US, (199806), vol. 30, no. 3, ISSN 0145-479X, pages 277 - 284, XP008016733 [A] * page 281, column 1, paragraph 2; table 1 *

DOI:   http://dx.doi.org/10.1023/A:1020501021222
 [A]  - SCHOLZ THOMAS D ET AL, "Ontogeny of malate-aspartate shuttle capacity and gene expression in cardiac mitochondria", AMERICAN JOURNAL OF PHYSIOLOGY, (199803), vol. 274, no. 3 PART 1, ISSN 0002-9513, pages C780 - C788, XP002303865 [A] * figures 4c,5c *
 [A]  - ZHANG CHEN-YU ET AL, "Assessment of uncoupling activity of uncoupling protein 3 using a yeast heterologous expression system.", FEBS LETTERS, (19990423), vol. 449, no. 2-3, ISSN 0014-5793, pages 129 - 134, XP002200190 [A] * figure 3 *

DOI:   http://dx.doi.org/10.1016/S0014-5793(99)00441-X
 [A]  - DAS KALLOL ET AL, "Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue.", BIOCHEMICAL JOURNAL, (19991201), vol. 344, no. 2, ISSN 0264-6021, pages 313 - 320, XP008003598 [A] * the whole document *

DOI:   http://dx.doi.org/10.1042/0264-6021:3440313
 [A]  - WALKER JOHN E ET AL, "The mitochondrial transport protein superfamily.", JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, (1993), vol. 25, no. 5, ISSN 0145-479X, pages 435 - 446, XP002089542

DOI:   http://dx.doi.org/10.1007/BF01108401
 [A]  - JEZEK P ET AL, "Fatty acid cycling mechanism and mitochondrial uncoupling proteins", BIOCHIMICA ET BIOPHYSICA ACTA. BIOENERGETICS, AMSTERDAM, NL, (19980610), vol. 1365, no. 1-2, ISSN 0005-2728, pages 319 - 327, XP004338771

DOI:   http://dx.doi.org/10.1016/S0005-2728(98)00084-X
 [A]  - YU AND GIBBS, "Homo sapiens clone 24408 2-oxoglutarate carrier protein mRNA, complete cds.", EMBL, EBI, Hinxton, UK, (19991205), Database accession no. AF070548, XP002200191 [A] * the whole document *
 [PX]  - YU XING XIAN ET AL, "Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: Contrast with the unique cold-induced mitochondrial carrier CGI-69.", BIOCHEMICAL JOURNAL, (20010115), vol. 353, no. 2, ISSN 0264-6021, pages 369 - 375, XP001059156 [PX] 1-26 * the whole document *

DOI:   http://dx.doi.org/10.1042/0264-6021:3530369
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