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Extract from the Register of European Patents

EP About this file: EP1620562

EP1620562 - MODULATION OF TELOMERE-INITIATED CELL SIGNALING [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  14.10.2011
Database last updated on 29.10.2024
Most recent event   Tooltip14.10.2011Application deemed to be withdrawnpublished on 16.11.2011  [2011/46]
Applicant(s)For all designated states
Trustees of Boston University
One Sherborn Street
Boston, MA 02215 / US
[2006/05]
Inventor(s)01 / GILCHREST, Barbara, A.
67 Walnut Place
Brookline, MA 02146 / US
02 / ELLER, Mark
49 Warren Avenue, No. 4
Boston, MA 02116 / US
 [2006/05]
Representative(s)den Hartog, Jeroen H.J., et al
Hoyng Rokh Monegier LLP
Rembrandt Tower, 31st Floor
Amstelplein 1
1096 HA Amsterdam / NL
[N/P]
Former [2011/43]den Hartog, Jeroen H.J., et al
Hoyng Monegier LLP Rembrandt Tower, 31st Floor Amstelplein 1
1096 HA Amsterdam / NL
Former [2008/34]Rasser, Jacobus Cornelis, et al
Howrey LLP Rembrandt Tower, 31st Floor Amstelplein 1
1096 HA Amsterdam / NL
Former [2006/05]Rasser, Jacobus Cornelis, et al
Howrey Simon Arnold & White P.O. Box 94361
1090 GJ Amsterdam / NL
Application number, filing date04702134.014.01.2004
[2006/05]
WO2004US00819
Priority number, dateWO2003US1139311.04.2003         Original published format: PCT/US0311/393
[2006/05]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004094655
Date:04.11.2004
Language:EN
[2004/45]
Type: A2 Application without search report 
No.:EP1620562
Date:01.02.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 04.11.2004 takes the place of the publication of the European patent application.
[2006/05]
Search report(s)International search report - published on:US14.09.2006
(Supplementary) European search report - dispatched on:EP29.05.2007
ClassificationIPC:C07H21/04, A01N43/04, C12Q1/68, C12P19/34, C12N5/00
[2006/45]
CPC:
C12Q1/6886 (EP); A61P17/00 (EP); A61P17/16 (EP);
A61P35/00 (EP); A61P35/02 (EP); A61P37/06 (EP);
A61P43/00 (EP); C12Q2600/136 (EP) (-)
Former IPC [2006/05]C12Q1/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2006/05]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:MODULATION DER TELOMERINITIIERTEN ZELLSIGNALISIERUNG[2006/05]
English:MODULATION OF TELOMERE-INITIATED CELL SIGNALING[2006/05]
French:MODULATION DE SIGNALISATION CELLULAIRE INITIEE PAR TELOMERE[2006/05]
Entry into regional phase10.11.2005National basic fee paid 
10.11.2005Search fee paid 
10.11.2005Designation fee(s) paid 
10.11.2005Examination fee paid 
Examination procedure10.11.2005Amendment by applicant (claims and/or description)
10.11.2005Examination requested  [2006/05]
27.08.2009Despatch of a communication from the examining division (Time limit: M06)
04.03.2010Reply to a communication from the examining division
10.11.2010Despatch of a communication from the examining division (Time limit: M06)
21.05.2011Application deemed to be withdrawn, date of legal effect  [2011/46]
27.06.2011Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2011/46]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  27.08.2009
Fees paidRenewal fee
10.11.2005Renewal fee patent year 03
21.02.2007Renewal fee patent year 04
28.03.2008Renewal fee patent year 05
14.01.2009Renewal fee patent year 06
13.01.2010Renewal fee patent year 07
14.01.2011Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.01.200704   M06   Fee paid on   21.02.2007
31.01.200805   M06   Fee paid on   28.03.2008
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Documents cited:Search[X]WO9949042  (ICOS CORP [US]) [X] 4,5 * page 36, lines 10-18 *;
 [X]WO03012125  (RIGEL PHARMACEUTICALS INC [US], et al) [X] 1-11,13,15,47-51,53-55 * abstract * * page 29, line 6 - page 33, line 12; figure 29 *;
 [X]  - ELLER MARK S ET AL, "Induction of a p95/Nbs1-mediated S phase checkpoint by telomere 3' overhang specific DNA.", FASEB JOURNAL, (200302), vol. 17, no. 2, ISSN 0892-6638, pages 152 - 162, XP002417039 [X] 53-56 * abstract * * page 152, column 1, paragraph 2 - page 153, column 2, paragraph 2 * * page 159, column 2, paragraph 2 - page 160, column 2, paragraph 2 * * figure 9 *

DOI:   http://dx.doi.org/10.1096/fj.02-0197com
 [X]  - PAULL TANYA T ET AL, "A mechanistic basis for Mre11-directed DNA joining at microhomologies", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (20000606), vol. 97, no. 12, ISSN 0027-8424, pages 6409 - 6414, XP002417040 [X] 1-4,8,9,53-55 * abstract * * page 6409, column 1, paragraph 2 - column 2, paragraph 3 * * page 6411, column 1, paragraph 4 - page 6412, column 2, paragraph 1 * * page 6413, column 2, paragraphs 2-4 *

DOI:   http://dx.doi.org/10.1073/pnas.110144297
 [A]  - LI GUANG-ZHI ET AL, "Evidence that exposure of the telomere 3' overhang sequence induces senescence.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (20030121), vol. 100, no. 2, ISSN 0027-8424, pages 527 - 531, XP002972897 [A] * abstract * * page 528, column 2, paragraph 1 * * page 529, column 1, paragraph 2 - page 531, column 2, paragraph 2; figure 5 *

DOI:   http://dx.doi.org/10.1073/pnas.0235444100
 [A]  - PETRINI J H J ET AL, "ISOLATION AND CHARACTERIZATION OF THE HUMAN MRE11 HOMOLOGUE", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, (199509), vol. 29, no. 1, ISSN 0888-7543, pages 80 - 86, XP002941671 [A] * abstract *

DOI:   http://dx.doi.org/10.1006/geno.1995.1217
 [PX]  - XU M ET AL, "Treatment of cells with Mre11 siRNA increases radiation sensitivity and reduces heat induced radiosensitization.", INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, & 45TH ANNUAL MEETING OF THE AMERICAN SOCIETY FOR THERAPEUTIC RADIOLOGY AND ONCOLOGY; SALT LAKE CITY, UTAH, USA; OCTOBER 19-23, 2003, (2003), vol. 57, no. 2 Supplement, ISSN 0360-3016, pages S144 - S145, XP002417041 [PX] 4,5 * abstract *

DOI:   http://dx.doi.org/10.1016/S0360-3016(03)00909-X
International search[X]US5958680  (VILLEPONTEAU BRYANT [US], et al);
 [X]  - ANSELMET ET AL., "Non-antisense cellular responses to oligonucleotides", FEBS LETTERS, (20020116), vol. 510, no. 3, pages 175 - 180, XP004332636

DOI:   http://dx.doi.org/10.1016/S0014-5793(01)03248-3
 [X]  - GLUKHOV ET AL., "Inhibition of telomerase activity of melanoma cells in vitro by antisense oligonucleotides", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (19980720), vol. 248, no. 2, pages 368 - 371, XP000961269

DOI:   http://dx.doi.org/10.1006/bbrc.1998.8801
 [X]  - ZHIHUI ET AL., "Inhibitory effect of a liposome-mediated antisense oligodeoxynucleotide on telomerase activity in a human gastric cancer cell line", CHINESE JOURNAL OF DIGESTIVE DISEASES, (2001), vol. 2, pages 65 - 68, XP003012222

DOI:   http://dx.doi.org/10.1046/j.1443-9573.2001.00031.x
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