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Extract from the Register of European Patents

EP About this file: EP1597265

EP1597265 - GLYCOSOLATED ENKEPHALIN AGENTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  20.02.2009
Database last updated on 18.11.2024
Most recent event   Tooltip20.02.2009Application deemed to be withdrawnpublished on 25.03.2009  [2009/13]
Applicant(s)For all designated states
The Arizona Board of Regents on behalf of the University of Arizona
P.O. Box 210158
Tucson AZ 85721-0158 / US
[N/P]
Former [2005/47]For all designated states
The Arizona Board of Regents on behalf of the University of Arizona
888 N. Euclid Avenue, Room 204, P.O. Box 210158
Tucson, AZ 85721-0158 / US
Inventor(s)01 / POLT, Robin, L.
2608 North Martin Avenue
Tucson, AZ 85719 / US
02 / BILSKY, Edward, J.
P.O. Box 248
Biddeford Pool, ME 04006 / US
 [2005/47]
Representative(s)Duckworth, Timothy John
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2005/47]Duckworth, Timothy John
J.A. Kemp & Co., 14 South Square, Gray's Inn
London WC1R 5JJ / GB
Application number, filing date04714123.924.02.2004
[2005/47]
WO2004US05340
Priority number, dateUS20030449989P25.02.2003         Original published format: US 449989 P
[2005/47]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004075843
Date:10.09.2004
Language:EN
[2004/37]
Type: A2 Application without search report 
No.:EP1597265
Date:23.11.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 10.09.2004 takes the place of the publication of the European patent application.
[2005/47]
Search report(s)International search report - published on:US17.03.2005
(Supplementary) European search report - dispatched on:EP20.03.2007
ClassificationIPC:A61K38/14, A61K38/33
[2007/16]
CPC:
C07K14/70 (EP,US); A61K38/33 (EP,US); A61K9/0019 (EP,US);
A61P25/04 (EP); A61P29/00 (EP)
Former IPC [2005/47]C07H5/06, C07H7/00, C07H9/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/47]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:GLYCOSYLIERTE ENKEPHALINMITTEL[2005/47]
English:GLYCOSOLATED ENKEPHALIN AGENTS[2005/47]
French:AGENTS ENCEPHALINIQUES GLYCOSOLES[2005/47]
Entry into regional phase13.06.2005National basic fee paid 
13.06.2005Search fee paid 
13.06.2005Designation fee(s) paid 
13.06.2005Examination fee paid 
Examination procedure07.09.2004Request for preliminary examination filed
International Preliminary Examining Authority: US
13.06.2005Examination requested  [2005/47]
05.06.2007Amendment by applicant (claims and/or description)
22.02.2008Despatch of a communication from the examining division (Time limit: M06)
04.09.2008Application deemed to be withdrawn, date of legal effect  [2009/13]
10.10.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2009/13]
Fees paidRenewal fee
14.02.2006Renewal fee patent year 03
14.02.2007Renewal fee patent year 04
13.02.2008Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XY]  - ELMAGBARI NURA ET AL, "Antinociceptive structure activity studies with novel opioid glycopeptides", FASEB JOURNAL, & ANNUAL MEETING OF THE FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY ON EXPERIMENTAL BIOL; ORLANDO, FLORIDA, USA; MARCH 31-APRIL 04, 2001, (20010308), vol. 15, no. 5, ISSN 0892-6638, page A915, XP008075623 [X] 1,4-6,8 * abstract * [Y] 1-10
 [X]  - MITCHELL S A ET AL, "Solid-phase synthesis of o-linked glycopepetide analoguesof enkephalin", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, US, (2001), vol. 66, ISSN 0022-3263, pages 2327 - 2342, XP002983423 [X] 1,4-6 * abstract * * page 2328, column 1, paragraphs 2,3 * * page 2328, column 2, paragraphs 1,2 *

DOI:   http://dx.doi.org/10.1021/jo005712m
 [Y]  - BILSKY EDWARD J ET AL, "Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability", JOURNAL OF MEDICINAL CHEMISTRY, (20000629), vol. 43, no. 13, ISSN 0022-2623, pages 2586 - 2590, XP002421956 [Y] 1-10 * abstract * * page 2587, column 1, paragraph 3; figure 1; compounds 1,2 *

DOI:   http://dx.doi.org/10.1021/jm000077y
International search[Y]US4407794  (ROQUES BERNARD [FR], et al);
 [A]US5767254  (POLT ROBIN L [US])
 [X]  - HORVAT ET AL., "A new utility of O-glycosylpseudoureas for synthesis of glucopeptides and (1->6)-disaccharides", SYNTHESIS, (1986), vol. 3, pages 209 - 211, XP008075680

DOI:   http://dx.doi.org/10.1055/s-1986-31617
 [X]  - MITCHELL ET AL., "Solid-phase synthesis of o-linked glycopepetide analoguesof enkephalin", J. ORG. CHEM., (2001), vol. 66, pages 2327 - 2342, XP002983423

DOI:   http://dx.doi.org/10.1021/jo005712m
 [X]  - ELMAGBARI ET AL., "Antinociceptive structure activity studies with novel opioid glycopeptides", FASEB J., (20010308), vol. 15, no. 5, page A915, XP008075623
 [XP]  - PALIAN ET AL., "Glycopeptide-membrane interaction: glycosyl enkephalin analogues adopt turn conformations by NMR and CD in amphipathic media", JACS, (200304), vol. 125, pages 5823 - 5831, XP002983424

DOI:   http://dx.doi.org/10.1021/ja0268635
 [XP]  - POLT ET AL., "Glycosylated enkephalins penetrate the blood-brain barrier adsportive endocytosis-analgesia superior to morphine", ABSTRACT OF PAPERS: 225TH ACS NAT'I MTG, NEW ORLEANS, LA, USA, (20030323), XP008075621
 [A]  - EGLETON ET AL., "Improved bioavailability to the brain of glycosylated met-enkephalin analogs", BRAIN RESEARCH, (2001), vol. 881, pages 37 - 46, XP002234522

DOI:   http://dx.doi.org/10.1016/S0006-8993(00)02794-3
Examination   - POLT R. ET AL, "Glycopeptide analgesics", DRUGS OF THE FUTURE, (20010601), vol. 26, no. 6, doi:10.1358/dof.2001.026.06.668342, pages 561 - 576, XP007904099

DOI:   http://dx.doi.org/10.1358/dof.2001.026.06.668342
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.