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Extract from the Register of European Patents

EP About this file: EP1601772

EP1601772 - MODIFIED TERT PROMOTER WITH ENHANCED TUMOR-SPECIFICITY AND STRENGTH AND RECOMBINANT VECTOR COMPRISING THE SAME [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  28.11.2008
Database last updated on 13.11.2024
Most recent event   Tooltip12.11.2010Lapse of the patent in a contracting state
New state(s): GR		published on 15.12.2010  [2010/50]
Applicant(s)For all designated states
Industry-Academic Cooperation Foundation, Yonsei University
134, Sinchon-dong Seodaemun-gu
Seoul 120-749 / KR
[2008/25]
Former [2006/13]For all designated states
Industry-Academic Cooperation Foundation
Yonsei University 134, Sinchon-dong, Seodaemun-gu Seoul
120-749 / KR
Former [2005/49]For all designated states
Yun, Chae-Ok
101, TaeHang Villa, 551-15 Banpo-dong, Seocho-gu
Seoul 137-807 / KR
For all designated states
KIM, Joo-Hang
C-1007 Twinbil, Mok 5-dong, Yangcheon-gu
Seoul 158-055 / KR
Inventor(s)01 / YUN, Chae-Ok
301, Bienetre, 86-5, Banpo4-dong, Seocho-gu
Seoul 137-805 / KR
02 / KIM, Joo-Hang
C-1007 Twinville, Mok 5-dong, Yangcheon-gu
Seoul 158-055 / KR
03 / YANG, Jai-Myung
A-1306 Kyeongbok, 276 Nonhyeon-dong, Gangnam-gu
Seoul 135-010 / KR
 [2007/12]
Former [2005/49]01 / YUN, Chae-Ok
101, TaeHang Villa, 551-15 Banpo-dong, Seocho-gu
Seoul 137-807 / KR
02 / KIM, Joo-Hang
C-1007 Twinbil, Mok 5-dong, Yangcheon-gu
Seoul 158-055 / KR
03 / YANG, Jai-Myung
A-1306 Kyeongbok, 276 Nonhyeon-dong, Gangnam-gu
Seoul 135-010 / KR
Representative(s)Schnabel, Jörg, et al
Habermann, Hruschka & Schnabel
Montgelasstrasse 2
81679 München / DE
[N/P]
Former [2006/13]Schnabel, Jörg, et al
Habermann, Hruschka & Schnabel Montgelasstrasse 2
81679 München / DE
Former [2005/49]Schnabel, Jörg
Habermann, Hruschka & Schnabel Montgelasstrasse 2
81679 München / DE
Application number, filing date04715577.527.02.2004
[2005/49]
WO2004KR00427
Priority number, dateKR2003001236427.02.2003         Original published format: KR 2003012364
[2005/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004076668
Date:10.09.2004
Language:EN
[2004/37]
Type: A1 Application with search report 
No.:EP1601772
Date:07.12.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 10.09.2004 takes the place of the publication of the European patent application.
[2005/49]
Type: B1 Patent specification 
No.:EP1601772
Date:23.01.2008
Language:EN
[2008/04]
Search report(s)International search report - published on:KR10.09.2004
(Supplementary) European search report - dispatched on:EP13.07.2006
ClassificationIPC:C12N15/52, C12N7/00, A61K35/76
[2005/49]
CPC:
C12N15/86 (EP,US); C12N15/52 (KR); A61K38/45 (EP,US);
A61P35/00 (EP); C12N9/1276 (EP,US); A61K48/00 (EP,US);
C12N2710/10343 (EP,US); C12N2830/008 (EP,US); C12N2830/85 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/49]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:MODIFIZIERTER TERT-PROMOTOR MIT VERBESSERTER TUMORSPEZIFITÄT UND STÄRKE SOWIE DIESEN ENTHALTENDER REKOMBINANTER VEKTOR[2005/49]
English:MODIFIED TERT PROMOTER WITH ENHANCED TUMOR-SPECIFICITY AND STRENGTH AND RECOMBINANT VECTOR COMPRISING THE SAME[2005/49]
French:PROMOTEUR DE TERT MODIFIE PRESENTANT UNE SPECIFICITE DE TUMEUR ET UNE RESISTANCE AMELIOREES ET VECTEUR RECOMBINANT COMPRENANT LEDIT PROMOTEUR[2005/49]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase26.09.2005National basic fee paid 
26.09.2005Search fee paid 
26.09.2005Designation fee(s) paid 
26.09.2005Examination fee paid 
Examination procedure27.12.2004Request for preliminary examination filed
International Preliminary Examining Authority: KR
26.09.2005Examination requested  [2005/49]
17.11.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
09.08.2007Communication of intention to grant the patent
13.11.2007Fee for grant paid
13.11.2007Fee for publishing/printing paid
Opposition(s)24.10.2008No opposition filed within time limit [2009/01]
Request for further processing for:20.11.2006Request for further processing filed
20.11.2006Full payment received (date of receipt of payment)
Request granted
01.12.2006Decision despatched
Fees paidRenewal fee
26.09.2005Renewal fee patent year 03
09.02.2007Renewal fee patent year 04
14.12.2007Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT23.01.2008
CY23.01.2008
CZ23.01.2008
DK23.01.2008
EE23.01.2008
FI23.01.2008
IT23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
TR23.01.2008
IE27.02.2008
LU27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
GR24.04.2008
ES04.05.2008
PT23.06.2008
HU24.07.2008
[2010/50]
Former [2010/38]AT23.01.2008
CY23.01.2008
CZ23.01.2008
DK23.01.2008
EE23.01.2008
FI23.01.2008
IT23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
TR23.01.2008
IE27.02.2008
LU27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
HU24.07.2008
Former [2010/34]AT23.01.2008
CY23.01.2008
CZ23.01.2008
DK23.01.2008
EE23.01.2008
FI23.01.2008
IT23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
IE27.02.2008
LU27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
HU24.07.2008
Former [2010/33]AT23.01.2008
CY23.01.2008
CZ23.01.2008
DK23.01.2008
EE23.01.2008
FI23.01.2008
IT23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
IE27.02.2008
LU27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
Former [2009/41]AT23.01.2008
CY23.01.2008
CZ23.01.2008
DK23.01.2008
EE23.01.2008
FI23.01.2008
IT23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
IE27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
Former [2009/35]AT23.01.2008
CY23.01.2008
CZ23.01.2008
DK23.01.2008
EE23.01.2008
FI23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
IE27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
Former [2009/11]AT23.01.2008
CZ23.01.2008
DK23.01.2008
EE23.01.2008
FI23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
IE27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
Former [2009/08]AT23.01.2008
CZ23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
IE27.02.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
Former [2008/49]AT23.01.2008
CZ23.01.2008
DK23.01.2008
FI23.01.2008
NL23.01.2008
RO23.01.2008
SI23.01.2008
SK23.01.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
Former [2008/46]AT23.01.2008
DK23.01.2008
FI23.01.2008
SI23.01.2008
MC28.02.2008
BG23.04.2008
SE23.04.2008
ES04.05.2008
PT23.06.2008
Former [2008/44]AT23.01.2008
FI23.01.2008
SI23.01.2008
BG23.04.2008
ES04.05.2008
PT23.06.2008
Former [2008/42]AT23.01.2008
FI23.01.2008
BG23.04.2008
ES04.05.2008
PT23.06.2008
Former [2008/39]AT23.01.2008
FI23.01.2008
BG23.04.2008
ES04.05.2008
Former [2008/36]FI23.01.2008
ES04.05.2008
Documents cited:Search[X]WO03013555  (UNIV TEXAS [US], et al) [X] 1-28 * the whole document *;
 [X]  - KIRCH HANS-CHRISTOPH ET AL, "Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system", ONCOGENE, (20021114), vol. 21, no. 52, ISSN 0950-9232, pages 7991 - 8000, XP002387757 [X] 1-28 * the whole document *

DOI:   http://dx.doi.org/10.1038/sj.onc.1205965
 [X]  - WICK ET AL, "Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT)", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER, AMSTERDAM, NL, (19990517), vol. 232, ISSN 0378-1119, pages 97 - 106, XP004166807 [X] 1-5 * figure 3 *

DOI:   http://dx.doi.org/10.1016/S0378-1119(99)00108-0
 [X]  - GREENBERG R A ET AL, "TELOMERASE REVERSE TRANSCRIPTASE GENE IS A DIRECT TARGET OF C-MYC BUT IS NOT FUNCTIONALLY EQUIVALENT IN CELLULAR TRANSFORMATION", ONCOGENE, BASINGSTOKE, HANTS, GB, (1999), vol. 18, ISSN 0950-9232, pages 1219 - 1226, XP000939120 [X] 1-5 * figure 3 *

DOI:   http://dx.doi.org/10.1038/sj.onc.1202669
International search[X]WO0046355  (GERON CORP [US], et al);
 [XP]  - EUNHEE KIM ET AL., "Ad-mTERT-d19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner.", HUMAN GENE THERAPY, (200310), vol. 14, pages 1415 - 1428, XP008057972

DOI:   http://dx.doi.org/10.1089/104303403769211637
 [X]  - SATORU KYO ET AL., "SP1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).", NUCLEIC ACID RESEARCH, (2000), vol. 28, no. 3, pages 669 - 677, XP008057985

DOI:   http://dx.doi.org/10.1093/nar/28.3.669
 [X]  - MASAHIRO TAKAKURA ET AL., "Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transriptional activation in immortilized and cancer cell.", CANCER RESEARCH, (199902), vol. 59, no. 3, pages 551 - 557, XP002105209
 [X]  - IZUMI HORIKAWA ET AL., "Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene.", CANCER RESEARCH, (199902), vol. 59, no. 4, pages 826 - 830, XP002105210
 [Y]  - JAESUNG KIM ET AL, "EVALUATION OF E1B GENEATTENUATED REPLICATING ADENOVIRUSES FOR CANCER GENE THERAPY", CANCER GENE THERAPY, (2002), vol. 9, pages 725 - 736, XP008057984

DOI:   http://dx.doi.org/10.1038/sj.cgt.7700494
 [Y]  - KRISHNA J.FISHER ET AL, "RECOMBINANT ADENOVIRUS DELETED OF ALL VIRAL GENES FOR GENE THERAPY CYSTIC FIBROSIS", VIROLOGY, (1996), vol. 217, no. 1, pages 11 - 22, XP000619165

DOI:   http://dx.doi.org/10.1006/viro.1996.0088
 [Y]  - RAJENDRA KUMAR-SINGH ET AL, "ENCAPSIDATED ADENOVIRUS MINICHROMOSOMES ALLOW DELIVERY AND EXPRESSION OF A 14 KB DYSTROPHIN DNA TO MUSCLE CELLS", HUMAN MOLECULAR GENETICS, (1996), vol. 5, no. 7, pages 913 - 921, XP000791220

DOI:   http://dx.doi.org/10.1093/hmg/5.7.913
 [Y]  - BASSIMA ABDALLAH ET AL, "NON VIRAL GENE TRASFER: APPLICATIONS IN DEVELOPMENT BIOLOGY AND GENE THERAPY", BIOLOGY OF THE CELL, (1995), vol. 85, no. 1, pages 1 - 7, XP001010029

DOI:   http://dx.doi.org/10.1016/0248-4900(96)89122-2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.